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Logistic Regression, Dependencies, Non-Linear Data and Model Reduction
COMP6237 – Logistic Regression, Dependencies, Non-linear Data and Model Reduction Markus Brede [email protected] Lecture slides available here: http://users.ecs.soton.ac.uk/mb8/stats/datamining.html (Thanks to Jason Noble and Cosma Shalizi whose lecture materials I used to prepare) COMP6237: Logistic Regression ● Outline: – Introduction – Basic ideas of logistic regression – Logistic regression using R – Some underlying maths and MLE – The multinomial case – How to deal with non-linear data ● Model reduction and AIC – How to deal with dependent data – Summary – Problems Introduction ● Previous lecture: Linear regression – tried to predict a continuous variable from variation in another continuous variable (E.g. basketball ability from height) ● Here: Logistic regression – Try to predict results of a binary (or categorical) outcome variable Y from a predictor variable X – This is a classification problem: classify X as belonging to one of two classes – Occurs quite often in science … e.g. medical trials (will a patient live or die dependent on medication?) Dependent variable Y Predictor Variables X The Oscars Example ● A fictional data set that looks at what it takes for a movie to win an Oscar ● Outcome variable: Oscar win, yes or no? ● Predictor variables: – Box office takings in millions of dollars – Budget in millions of dollars – Country of origin: US, UK, Europe, India, other – Critical reception (scores 0 … 100) – Length of film in minutes – This (fictitious) data set is available here: https://www.southampton.ac.uk/~mb1a10/stats/filmData.txt Predicting Oscar Success ● Let's start simple and look at only one of the predictor variables ● Do big box office takings make Oscar success more likely? ● Could use same techniques as below to look at budget size, film length, etc. -
Heteroscedastic Errors
Heteroscedastic Errors ◮ Sometimes plots and/or tests show that the error variances 2 σi = Var(ǫi ) depend on i ◮ Several standard approaches to fixing the problem, depending on the nature of the dependence. ◮ Weighted Least Squares. ◮ Transformation of the response. ◮ Generalized Linear Models. Richard Lockhart STAT 350: Heteroscedastic Errors and GLIM Weighted Least Squares ◮ Suppose variances are known except for a constant factor. 2 2 ◮ That is, σi = σ /wi . ◮ Use weighted least squares. (See Chapter 10 in the text.) ◮ This usually arises realistically in the following situations: ◮ Yi is an average of ni measurements where you know ni . Then wi = ni . 2 ◮ Plots suggest that σi might be proportional to some power of 2 γ γ some covariate: σi = kxi . Then wi = xi− . Richard Lockhart STAT 350: Heteroscedastic Errors and GLIM Variances depending on (mean of) Y ◮ Two standard approaches are available: ◮ Older approach is transformation. ◮ Newer approach is use of generalized linear model; see STAT 402. Richard Lockhart STAT 350: Heteroscedastic Errors and GLIM Transformation ◮ Compute Yi∗ = g(Yi ) for some function g like logarithm or square root. ◮ Then regress Yi∗ on the covariates. ◮ This approach sometimes works for skewed response variables like income; ◮ after transformation we occasionally find the errors are more nearly normal, more homoscedastic and that the model is simpler. ◮ See page 130ff and check under transformations and Box-Cox in the index. Richard Lockhart STAT 350: Heteroscedastic Errors and GLIM Generalized Linear Models ◮ Transformation uses the model T E(g(Yi )) = xi β while generalized linear models use T g(E(Yi )) = xi β ◮ Generally latter approach offers more flexibility. -
Logistic Regression Maths and Statistics Help Centre
Logistic regression Maths and Statistics Help Centre Many statistical tests require the dependent (response) variable to be continuous so a different set of tests are needed when the dependent variable is categorical. One of the most commonly used tests for categorical variables is the Chi-squared test which looks at whether or not there is a relationship between two categorical variables but this doesn’t make an allowance for the potential influence of other explanatory variables on that relationship. For continuous outcome variables, Multiple regression can be used for a) controlling for other explanatory variables when assessing relationships between a dependent variable and several independent variables b) predicting outcomes of a dependent variable using a linear combination of explanatory (independent) variables The maths: For multiple regression a model of the following form can be used to predict the value of a response variable y using the values of a number of explanatory variables: y 0 1x1 2 x2 ..... q xq 0 Constant/ intercept , 1 q co efficients for q explanatory variables x1 xq The regression process finds the co-efficients which minimise the squared differences between the observed and expected values of y (the residuals). As the outcome of logistic regression is binary, y needs to be transformed so that the regression process can be used. The logit transformation gives the following: p ln 0 1x1 2 x2 ..... q xq 1 p p p probabilty of event occuring e.g. person dies following heart attack, odds ratio 1- p If probabilities of the event of interest happening for individuals are needed, the logistic regression equation exp x x .... -
Power Comparisons of the Mann-Whitney U and Permutation Tests
Power Comparisons of the Mann-Whitney U and Permutation Tests Abstract: Though the Mann-Whitney U-test and permutation tests are often used in cases where distribution assumptions for the two-sample t-test for equal means are not met, it is not widely understood how the powers of the two tests compare. Our goal was to discover under what circumstances the Mann-Whitney test has greater power than the permutation test. The tests’ powers were compared under various conditions simulated from the Weibull distribution. Under most conditions, the permutation test provided greater power, especially with equal sample sizes and with unequal standard deviations. However, the Mann-Whitney test performed better with highly skewed data. Background and Significance: In many psychological, biological, and clinical trial settings, distributional differences among testing groups render parametric tests requiring normality, such as the z test and t test, unreliable. In these situations, nonparametric tests become necessary. Blair and Higgins (1980) illustrate the empirical invalidity of claims made in the mid-20th century that t and F tests used to detect differences in population means are highly insensitive to violations of distributional assumptions, and that non-parametric alternatives possess lower power. Through power testing, Blair and Higgins demonstrate that the Mann-Whitney test has much higher power relative to the t-test, particularly under small sample conditions. This seems to be true even when Welch’s approximation and pooled variances are used to “account” for violated t-test assumptions (Glass et al. 1972). With the proliferation of powerful computers, computationally intensive alternatives to the Mann-Whitney test have become possible. -
Generalized Linear Models
CHAPTER 6 Generalized linear models 6.1 Introduction Generalized linear modeling is a framework for statistical analysis that includes linear and logistic regression as special cases. Linear regression directly predicts continuous data y from a linear predictor Xβ = β0 + X1β1 + + Xkβk.Logistic regression predicts Pr(y =1)forbinarydatafromalinearpredictorwithaninverse-··· logit transformation. A generalized linear model involves: 1. A data vector y =(y1,...,yn) 2. Predictors X and coefficients β,formingalinearpredictorXβ 1 3. A link function g,yieldingavectoroftransformeddataˆy = g− (Xβ)thatare used to model the data 4. A data distribution, p(y yˆ) | 5. Possibly other parameters, such as variances, overdispersions, and cutpoints, involved in the predictors, link function, and data distribution. The options in a generalized linear model are the transformation g and the data distribution p. In linear regression,thetransformationistheidentity(thatis,g(u) u)and • the data distribution is normal, with standard deviation σ estimated from≡ data. 1 1 In logistic regression,thetransformationistheinverse-logit,g− (u)=logit− (u) • (see Figure 5.2a on page 80) and the data distribution is defined by the proba- bility for binary data: Pr(y =1)=y ˆ. This chapter discusses several other classes of generalized linear model, which we list here for convenience: The Poisson model (Section 6.2) is used for count data; that is, where each • data point yi can equal 0, 1, 2, ....Theusualtransformationg used here is the logarithmic, so that g(u)=exp(u)transformsacontinuouslinearpredictorXiβ to a positivey ˆi.ThedatadistributionisPoisson. It is usually a good idea to add a parameter to this model to capture overdis- persion,thatis,variationinthedatabeyondwhatwouldbepredictedfromthe Poisson distribution alone. -
Research Report Statistical Research Unit Goteborg University Sweden
Research Report Statistical Research Unit Goteborg University Sweden Testing for multivariate heteroscedasticity Thomas Holgersson Ghazi Shukur Research Report 2003:1 ISSN 0349-8034 Mailing address: Fax Phone Home Page: Statistical Research Nat: 031-77312 74 Nat: 031-77310 00 http://www.stat.gu.se/stat Unit P.O. Box 660 Int: +4631 773 12 74 Int: +4631 773 1000 SE 405 30 G6teborg Sweden Testing for Multivariate Heteroscedasticity By H.E.T. Holgersson Ghazi Shukur Department of Statistics Jonkoping International GOteborg university Business school SE-405 30 GOteborg SE-55 111 Jonkoping Sweden Sweden Abstract: In this paper we propose a testing technique for multivariate heteroscedasticity, which is expressed as a test of linear restrictions in a multivariate regression model. Four test statistics with known asymptotical null distributions are suggested, namely the Wald (W), Lagrange Multiplier (LM), Likelihood Ratio (LR) and the multivariate Rao F-test. The critical values for the statistics are determined by their asymptotic null distributions, but also bootstrapped critical values are used. The size, power and robustness of the tests are examined in a Monte Carlo experiment. Our main findings are that all the tests limit their nominal sizes asymptotically, but some of them have superior small sample properties. These are the F, LM and bootstrapped versions of Wand LR tests. Keywords: heteroscedasticity, hypothesis test, bootstrap, multivariate analysis. I. Introduction In the last few decades a variety of methods has been proposed for testing for heteroscedasticity among the error terms in e.g. linear regression models. The assumption of homoscedasticity means that the disturbance variance should be constant (or homoscedastic) at each observation. -
An Introduction to Logistic Regression: from Basic Concepts to Interpretation with Particular Attention to Nursing Domain
J Korean Acad Nurs Vol.43 No.2, 154 -164 J Korean Acad Nurs Vol.43 No.2 April 2013 http://dx.doi.org/10.4040/jkan.2013.43.2.154 An Introduction to Logistic Regression: From Basic Concepts to Interpretation with Particular Attention to Nursing Domain Park, Hyeoun-Ae College of Nursing and System Biomedical Informatics National Core Research Center, Seoul National University, Seoul, Korea Purpose: The purpose of this article is twofold: 1) introducing logistic regression (LR), a multivariable method for modeling the relationship between multiple independent variables and a categorical dependent variable, and 2) examining use and reporting of LR in the nursing literature. Methods: Text books on LR and research articles employing LR as main statistical analysis were reviewed. Twenty-three articles published between 2010 and 2011 in the Journal of Korean Academy of Nursing were analyzed for proper use and reporting of LR models. Results: Logistic regression from basic concepts such as odds, odds ratio, logit transformation and logistic curve, assumption, fitting, reporting and interpreting to cautions were presented. Substantial short- comings were found in both use of LR and reporting of results. For many studies, sample size was not sufficiently large to call into question the accuracy of the regression model. Additionally, only one study reported validation analysis. Conclusion: Nurs- ing researchers need to pay greater attention to guidelines concerning the use and reporting of LR models. Key words: Logit function, Maximum likelihood estimation, Odds, Odds ratio, Wald test INTRODUCTION The model serves two purposes: (1) it can predict the value of the depen- dent variable for new values of the independent variables, and (2) it can Multivariable methods of statistical analysis commonly appear in help describe the relative contribution of each independent variable to general health science literature (Bagley, White, & Golomb, 2001). -
T-Statistic Based Correlation and Heterogeneity Robust Inference
t-Statistic Based Correlation and Heterogeneity Robust Inference Rustam IBRAGIMOV Economics Department, Harvard University, 1875 Cambridge Street, Cambridge, MA 02138 Ulrich K. MÜLLER Economics Department, Princeton University, Fisher Hall, Princeton, NJ 08544 ([email protected]) We develop a general approach to robust inference about a scalar parameter of interest when the data is potentially heterogeneous and correlated in a largely unknown way. The key ingredient is the following result of Bakirov and Székely (2005) concerning the small sample properties of the standard t-test: For a significance level of 5% or lower, the t-test remains conservative for underlying observations that are independent and Gaussian with heterogenous variances. One might thus conduct robust large sample inference as follows: partition the data into q ≥ 2 groups, estimate the model for each group, and conduct a standard t-test with the resulting q parameter estimators of interest. This results in valid and in some sense efficient inference when the groups are chosen in a way that ensures the parameter estimators to be asymptotically independent, unbiased and Gaussian of possibly different variances. We provide examples of how to apply this approach to time series, panel, clustered and spatially correlated data. KEY WORDS: Dependence; Fama–MacBeth method; Least favorable distribution; t-test; Variance es- timation. 1. INTRODUCTION property of the correlations. The key ingredient to the strategy is a result by Bakirov and Székely (2005) concerning the small Empirical analyses in economics often face the difficulty that sample properties of the usual t-test used for inference on the the data is correlated and heterogeneous in some unknown fash- mean of independent normal variables: For significance levels ion. -
Variance Partitioning in Multilevel Logistic Models That Exhibit Overdispersion
J. R. Statist. Soc. A (2005) 168, Part 3, pp. 599–613 Variance partitioning in multilevel logistic models that exhibit overdispersion W. J. Browne, University of Nottingham, UK S. V. Subramanian, Harvard School of Public Health, Boston, USA K. Jones University of Bristol, UK and H. Goldstein Institute of Education, London, UK [Received July 2002. Final revision September 2004] Summary. A common application of multilevel models is to apportion the variance in the response according to the different levels of the data.Whereas partitioning variances is straight- forward in models with a continuous response variable with a normal error distribution at each level, the extension of this partitioning to models with binary responses or to proportions or counts is less obvious. We describe methodology due to Goldstein and co-workers for appor- tioning variance that is attributable to higher levels in multilevel binomial logistic models. This partitioning they referred to as the variance partition coefficient. We consider extending the vari- ance partition coefficient concept to data sets when the response is a proportion and where the binomial assumption may not be appropriate owing to overdispersion in the response variable. Using the literacy data from the 1991 Indian census we estimate simple and complex variance partition coefficients at multiple levels of geography in models with significant overdispersion and thereby establish the relative importance of different geographic levels that influence edu- cational disparities in India. Keywords: Contextual variation; Illiteracy; India; Multilevel modelling; Multiple spatial levels; Overdispersion; Variance partition coefficient 1. Introduction Multilevel regression models (Goldstein, 2003; Bryk and Raudenbush, 1992) are increasingly being applied in many areas of quantitative research. -
Randomization Does Not Justify Logistic Regression
Statistical Science 2008, Vol. 23, No. 2, 237–249 DOI: 10.1214/08-STS262 c Institute of Mathematical Statistics, 2008 Randomization Does Not Justify Logistic Regression David A. Freedman Abstract. The logit model is often used to analyze experimental data. However, randomization does not justify the model, so the usual esti- mators can be inconsistent. A consistent estimator is proposed. Ney- man’s non-parametric setup is used as a benchmark. In this setup, each subject has two potential responses, one if treated and the other if untreated; only one of the two responses can be observed. Beside the mathematics, there are simulation results, a brief review of the literature, and some recommendations for practice. Key words and phrases: Models, randomization, logistic regression, logit, average predicted probability. 1. INTRODUCTION nπT subjects at random and assign them to the treatment condition. The remaining nπ subjects The logit model is often fitted to experimental C are assigned to a control condition, where π = 1 data. As explained below, randomization does not C π . According to Neyman (1923), each subject has− justify the assumptions behind the model. Thus, the T two responses: Y T if assigned to treatment, and Y C conventional estimator of log odds is difficult to in- i i if assigned to control. The responses are 1 or 0, terpret; an alternative will be suggested. Neyman’s where 1 is “success” and 0 is “failure.” Responses setup is used to define parameters and prove re- are fixed, that is, not random. sults. (Grammatical niceties apart, the terms “logit If i is assigned to treatment (T ), then Y T is ob- model” and “logistic regression” are used interchange- i served. -
Chapter 19: Logistic Regression
DISCOVERING STATISTICS USING SPSS Chapter 19: Logistic regression Smart Alex’s Solutions Task 1 A ‘display rule’ refers to displaying an appropriate emotion in a given situation. For example, if you receive a Christmas present that you don’t like, the appropriate emotional display is to smile politely and say ‘Thank you Why did you buy me this Auntie Kate, I’ve always wanted a rotting cabbage’. The crappy statistics textbook for Christmas, Auntie Kate? inappropriate emotional display is to start crying and scream ‘Why did you buy me a rotting cabbage, you selfish old bag?’ A psychologist measured children’s understanding of display rules (with a task that they could either pass or fail), their age (months), and their ability to understand others’ mental states (‘theory of mind’, measured with a false-belief task that they could pass or fail). The data are in Display.sav. Can display rule understanding (did the child pass the test: yes/no?) be predicted from the theory of mind (did the child pass the false-belief task: yes/no?), age and their interaction? The main analysis To carry out logistic regression, the data must be entered as for normal regression: they are arranged in the data editor in three columns (one representing each variable). Open the file Display.sav. Looking at the data editor, you should notice that both of the categorical variables have been entered as coding variables; that is, numbers have been specified to represent categories. For ease of interpretation, the outcome variable should be coded 1 (event occurred) and 0 (event did not occur); in this case, 1 represents having display rule understanding, and 0 represents an absence of display rule understanding. -
An Introduction to Biostatistics: Part 2
An introduction to biostatistics: part 2 Cavan Reilly September 4, 2019 Table of contents Statistical models Maximum likelihood estimation Linear models Multiple regression Confounding Statistical adjustments Contrasts Interactions Generalized linear models Logistic regression Model selection Statistical models Statistical models can be powerful tools for understanding complex relationships among variables. We will first suppose that we observe 2 continuous variables. Typically we would start out by looking at a scatterplot: so let's look at an example. Let's read in some data from the genetic association study we looked at in the previous lecture: fms=read.delim("http://www.biostat.umn.edu/~cavanr/FMS_data.txt") Statistical models Then we can just use the plot command as follows. > pdf("wght-hght.pdf") > plot(fms$Pre.height,fms$Pre.weight,xlab="Height",ylab="Weight") > dev.off() It looks like the 2 variables increase together, but we clearly don't have an equation like: Weight = β0 + β1Height; for 2 constants β0 and β1. Note: we look at the distribution of the response variable conditional on the explanatory variable. Correlation A commonly used measure of the extent to which 2 continuous variables have a linear association is the correlation coefficient. The cor function in R allows one to compute this summary. If it is positive then large values of one variable are generally associated with large values of the other. If it is negative then large values of one variables are associated with small values of the other. If the absolute value of the correlation coefficient exceeds 0.7 then there is a strong association, if less than 0.3 then weak, otherwise moderate.