Arachnides 86, 2018
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Hox Gene Duplications Correlate with Posterior Heteronomy in Scorpions
Downloaded from http://rspb.royalsocietypublishing.org/ on February 17, 2015 Hox gene duplications correlate with posterior heteronomy in scorpions Prashant P. Sharma1, Evelyn E. Schwager2, Cassandra G. Extavour2 and Ward C. Wheeler1 rspb.royalsocietypublishing.org 1Division of Invertebrate Zoology, American Museum of Natural History, Central Park West at 79th Street, New York, NY 10024, USA 2Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA Research The evolutionary success of the largest animal phylum, Arthropoda, has been attributed to tagmatization, the coordinated evolution of adjacent metameres Cite this article: Sharma PP, Schwager EE, to form morphologically and functionally distinct segmental regions called Extavour CG, Wheeler WC. 2014 Hox gene tagmata. Specification of regional identity is regulated by the Hox genes, of duplications correlate with posterior which 10 are inferred to be present in the ancestor of arthropods. With six heteronomy in scorpions. Proc. R. Soc. B 281: different posterior segmental identities divided into two tagmata, the bauplan of scorpions is the most heteronomous within Chelicerata. Expression 20140661. domains of the anterior eight Hox genes are conserved in previously surveyed http://dx.doi.org/10.1098/rspb.2014.0661 chelicerates, but it is unknown how Hox genes regionalize the three tagmata of scorpions. Here, we show that the scorpion Centruroides sculpturatus has two paralogues of all Hox genes except Hox3, suggesting cluster and/or whole genome duplication in this arachnid order. Embryonic anterior expression Received: 19 March 2014 domain boundaries of each of the last four pairs of Hox genes (two paralogues Accepted: 22 July 2014 each of Antp, Ubx, abd-A and Abd-B) are unique and distinguish segmental groups, such as pectines, book lungs and the characteristic tail, while main- taining spatial collinearity. -
Scorpion Venom: New Promise in the Treatment of Cancer
Acta Biológica Colombiana ISSN: 0120-548X ISSN: 1900-1649 Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de Biología SCORPION VENOM: NEW PROMISE IN THE TREATMENT OF CANCER GÓMEZ RAVE, Lyz Jenny; MUÑOZ BRAVO, Adriana Ximena; SIERRA CASTRILLO, Jhoalmis; ROMÁN MARÍN, Laura Melisa; CORREDOR PEREIRA, Carlos SCORPION VENOM: NEW PROMISE IN THE TREATMENT OF CANCER Acta Biológica Colombiana, vol. 24, no. 2, 2019 Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de Biología Available in: http://www.redalyc.org/articulo.oa?id=319060771002 DOI: 10.15446/abc.v24n2.71512 PDF generated from XML JATS4R by Redalyc Project academic non-profit, developed under the open access initiative Revisión SCORPION VENOM: NEW PROMISE IN THE TREATMENT OF CANCER Veneno de escorpión: Una nueva promesa en el tratamiento del cáncer Lyz Jenny GÓMEZ RAVE 12* Institución Universitaria Colegio Mayor de Antioquia, Colombia Adriana Ximena MUÑOZ BRAVO 12 Institución Universitaria Colegio Mayor de Antioquia, Colombia Jhoalmis SIERRA CASTRILLO 3 [email protected] Universidad de Santander, Colombia Laura Melisa ROMÁN MARÍN 1 Institución Universitaria Colegio Mayor de Antioquia, Colombia Carlos CORREDOR PEREIRA 4 Acta Biológica Colombiana, vol. 24, no. 2, 2019 Universidad Simón Bolívar, Colombia Universidad Nacional de Colombia, Facultad de Ciencias, Departamento de Biología Received: 04 April 2018 ABSTRACT: Cancer is a public health problem due to its high worldwide Revised document received: 29 December 2018 morbimortality. Current treatment protocols do not guarantee complete remission, Accepted: 07 February 2019 which has prompted to search for new and more effective antitumoral compounds. Several substances exhibiting cytostatic and cytotoxic effects over cancer cells might DOI: 10.15446/abc.v24n2.71512 contribute to the treatment of this pathology. -
Small Molecules in the Venom of the Scorpion Hormurus Waigiensis
biomedicines Article Small Molecules in the Venom of the Scorpion Hormurus waigiensis Edward R. J. Evans 1, Lachlan McIntyre 2, Tobin D. Northfield 3, Norelle L. Daly 1 and David T. Wilson 1,* 1 Centre for Molecular Therapeutics, AITHM, James Cook University, Cairns, QLD 4878, Australia; [email protected] (E.R.J.E.); [email protected] (N.L.D.) 2 Independent Researcher, P.O. Box 78, Bamaga, QLD 4876, Australia; [email protected] 3 Department of Entomology, Tree Fruit Research and Extension Center, Washington State University, Wenatchee, WA 98801, USA; [email protected] * Correspondence: [email protected]; Tel.: +61-7-4232-1707 Received: 30 June 2020; Accepted: 28 July 2020; Published: 31 July 2020 Abstract: Despite scorpion stings posing a significant public health issue in particular regions of the world, certain aspects of scorpion venom chemistry remain poorly described. Although there has been extensive research into the identity and activity of scorpion venom peptides, non-peptide small molecules present in the venom have received comparatively little attention. Small molecules can have important functions within venoms; for example, in some spider species the main toxic components of the venom are acylpolyamines. Other molecules can have auxiliary effects that facilitate envenomation, such as purines with hypotensive properties utilised by snakes. In this study, we investigated some non-peptide small molecule constituents of Hormurus waigiensis venom using LC/MS, reversed-phase HPLC, and NMR spectroscopy. We identified adenosine, adenosine monophosphate (AMP), and citric acid within the venom, with low quantities of the amino acids glutamic acid and aspartic acid also being present. -
The Predation of an Adult Colubrid Snake, Sibynophis Triangularis, by the Scorpion Heterometrus Laoticus in the Sakaerat Biosphere Reserve
Captive & Field Herpetology Volume 4 Issue 1 2020 Inverting the Food Web: The Predation of an Adult Colubrid Snake, Sibynophis triangularis, by the Scorpion Heterometrus laoticus in the Sakaerat Biosphere Reserve Jack Christie1, Everett Madsen1, Surachit Waengsothorn1, Max Dolton Jones1, 2,* 1Sakaerat Environmental Research Station, Nakhon Ratchasima, Thailand. 2Suranree University of Technology, Nakhon Ratchasima, Thailand. *Corresponding author, e-mail: [email protected] Abstract: system they occupy, is a well-researched and understood topic (Belovsky & Slade 1993; The predation of vertebrates by large tropical Murkin & Batt 1987; Nordberg et al. 2018). invertebrates is a rare phenomenon in nature, This particularly pertains to the predation of though not unprecedented. Scorpions in invertebrates by larger vertebrate predators. particular are evolutionarily equipped to take However, there are far fewer instances of on such a task. Despite the hunting strategy invertebrates consuming vertebrate prey items and primarily insectivorous diet of scorpions, within the available literature. Scorpions are they are known to opportunistically prey upon primarily fossorial ambush predators, emerging small vertebrate prey such as lizards, frogs and from their burrows and lying in wait at the birds. Herein, we describe the observation of entrance for unsuspecting prey to wander too an adult Asian forest scorpion (Heterometrus close (Williams 1987). Scorpions typically laoticus; Scorpiones; Scorpionidae) predating exhibit an insectivorous diet, with the upon an adult triangle many-toothed snake exception of a few species (Williams 1987), (Sibynophis triangularis; Squamata: and have been known to prey on frogs, birds, Colubridae). Although the opportunistic lizards and even snakes (McCormick & Polis, predation on snakes by scorpions has been 1982). -
Pet Health and Happiness Is Our Primary Concern
Pet Health and Happiness Is Our Primary Concern CONCISE CARE SHEETS PINK-TOES find more caresheets at nwzoo.com/care AND TREE SPIDERS INTRO QUICK TIPS PSALMOPOEUS The tropics of the New World or Americas are home to many popular The Trinidad Chevron (Psalmopoeus tree-dwelling tarantulas. These include a wide variety of “Pink-toes” of the » 76-82°F with a drop in tem- cambridgei] and Venezuelan Suntiger (P. genus Avicularia, the closely related Antilles “pink-toe” or tree tarantula perature at night (72-76ºF) irminia) are the best known members of (Caribena versicolor), the lightning-fast and agile Tapinauchenius and » Requires 70-80% humidity, a genus popular with tarantula keepers. a handful of species of Psalmopoeus like the Venezuelan Suntiger and but also good ventilation. Both are fairly large (P. cambridgei can Trinidad Chevron. » Most species will eat a reach a legspan of seven inches) and variety of arthropods and make exceptional display subjects for These tarantulas are found in a variety of subtropical and tropical habitats, small vertebrates yet thrive the spacious vertically-oriented forest but their general care is similar enough to cover them all in a single care on roaches or crickets in terrarium. Psalmopoeus tarantulas are sheet. Optimal captive husbandry is focused on providing warm, humid captivity. very hardy and often more forgiving of air in an enclosure that allows for sufficient ventilation. It is a balancing drier conditions than other New World act of sorts, but the conscientious and cautious keeper soon learns to err arboreal tarantulas. Both the Chevron on the side of good airflow as it is easier to add moisture than to correct and Suntiger appreciate a couple of layers of vertical cork bark slabs to overly damp or stagnant conditions. -
Felipe Jun Fuzita Molecular Physiology of Digestion In
FELIPE JUN FUZITA MOLECULAR PHYSIOLOGY OF DIGESTION IN ARACHNIDA: FUNCTIONAL AND COMPARATIVE-EVOLUTIONARY APPROACHES Thesis presented to the Programa de Pós-Graduação Interunidades em Biotecnologia USP/Instituto Butantan/IPT, to obtain the Title of Doctor in Biotechnology. São Paulo 2014 FELIPE JUN FUZITA MOLECULAR PHYSIOLOGY OF DIGESTION IN ARACHNIDA: FUNCTIONAL AND COMPARATIVE-EVOLUTIONARY APPROACHES Thesis presented to the Programa de Pós-Graduação Interunidades em Biotecnologia USP/Instituto Butantan/IPT, to obtain the Title of Doctor in Biotechnology. Concentration area: Biotechnology Advisor: Dr. Adriana Rios Lopes Rocha Corrected version. The original electronic version is available either in the library of the Institute of Biomedical Sciences and in the Digital Library of Theses and Dissertations of the University of Sao Paulo (BDTD). São Paulo 2014 DADOS DE CATALOGAÇÃO NA PUBLICAÇÃO (CIP) Serviço de Biblioteca e Informação Biomédica do Instituto de Ciências Biomédicas da Universidade de São Paulo © reprodução total Fuzita, Felipe Jun. Molecular physiology of digestion in Arachnida: functional and comparative-evolutionary approaches / Felipe Jun Fuzita. -- São Paulo, 2014. Orientador: Profa. Dra. Adriana Rios Lopes Rocha. Tese (Doutorado) – Universidade de São Paulo. Instituto de Ciências Biomédicas. Programa de Pós-Graduação Interunidades em Biotecnologia USP/IPT/Instituto Butantan. Área de concentração: Biotecnologia. Linha de pesquisa: Bioquímica, biologia molecular, espectrometria de massa. Versão do título para o português: Fisiologia molecular da digestão em Arachnida: abordagens funcional e comparativo-evolutiva. 1. Digestão 2. Aranha 3. Escorpião 4. Enzimologia 5. Proteoma 6. Transcriptoma I. Rocha, Profa. Dra. Adriana Rios Lopes I. Universidade de São Paulo. Instituto de Ciências Biomédicas. Programa de Pós-Graduação Interunidades em Biotecnologia USP/IPT/Instituto Butantan III. -
Sexual Dimorphism in the Asian Giant Forest Scorpion, Heterometrus Laoticus Couzijn, 1981
NU Science Journal 2007; 4(1): 42 - 52 Sexual Dimorphism in the Asian Giant Forest Scorpion, Heterometrus laoticus Couzijn, 1981 Ubolwan Booncham1*, Duangkhae Sitthicharoenchai2, Art-ong Pradatsundarasar2, Surisak Prasarnpun1 and Kumthorn Thirakhupt2 1Department of Biology, Faculty of Science, Naresuan University, Phitsanulok 65000 Thailand 2Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok 10400 Thailand *Corresponding author. E-mail address: [email protected] ABSTRACT Morphological characters of adult male and adult female giant forest scorpions, Heterometrus laoticus, in a mixed deciduous forest at Phitsanulok Wildlife Conservation Development and Extension Station showed sexual dimorphism. Among the observed characters, carapace width, chela length, chela width, telson length and shape of movable finger of adult male and female scorpions were obviously different. The pectines of males were also significantly longer, and the number of sensilla-bearing teeth in male scorpions was more than in females. Moreover, males had higher density of sensilla on the pectinal teeth than females. During the breeding season, mature males were mobile while mature females were mainly at their burrows. Keywords: Heterometrus laoticus, sexual dimorphism INTRODUCTION Sexual dimorphism is the difference in form between males and females of the same species. Sexual dimorphism, particularly sexual size dimorphism (SSD) has been observed in a large number of animal taxa (Blanckenhorn, 2005; Brown, 1996; David et al., 2003; Esperk and Tammaru, 2006; Herrel et al. 1999; Ozkan et al., 2006; Ranta et al. 1994; Shine, 1989; Walker and Rypstra, 2001 and Wangkulangkul, et al., 2005). Under the influence of natural and sexual selections, males and females often differ in costs and benefits of achieving some particular body sizes (Crowley, 2000; Gaffin and Broenell, 2001; Kladt, 2003; Mattoni, 2005). -
Target-Specificity in Scorpions
Toxins 2017, 9, 312, doi: 10.3390/toxins9100312 S1 of S3 Supplementary Materials: Target‐specificity in scorpions; Comparing lethality of scorpion venoms across arthropods and vertebrates Arie van der Meijden, Bjørn Koch, Tom van der Valk, Leidy J. Vargas‐Muñoz and Sebastian Estrada‐Gómez Table S1. Table with GenBank CO1 accession numbers. Voucher numbers refer to the specimens in the collection of CIBIO/InBio at the University of Porto. Species Voucher Accession number Androctonus australis Sc904 gi379647585 Leiurus quinquestriatus Sc1062 gi379647601 Buthus ibericus Sc112 gi290918312 Grosphus flavopiceus Sc1085 gi379647593 Centruroides gracilis gi71743793 Heterometrus laoticus Sc1084 gi555299473 Pandinus imperator Sc1050 gi379647587 Hadrurus arizonensis Sc1042 gi379647597 Iurus kraepelini Sc866 gi379647589 Table S2. Mean dry venom compound per individual. Several milkings were made per (sub)adult specimen in some cases. Species n Dry venom (mg) mg/milking Androctonus australis 21 23.5 1.12 Leiurus quinquestriatus 51 25.1 0.49 Buthus ibericus 47 41.6 0.89 Centruroides gracilis 42 22.5 0.54 Babycurus jacksoni 38 53.9 1.42 Grosphus grandidieri 19 103.9 5.47 Hadrurus arizonensis 9 75.3 8.37 Iurus sp.* 12 35.2 2.93 Heterometrus laoticus 21 119 5.67 Pandinus imperator 15 72.7 4.85 *2 I. dufoureius, 6 I. kraepelini, 4 I. sp. Toxins 2017, 9, 312, doi: 10.3390/toxins9100312 S2 of S3 Table S3. Toxicological analysis of the venom of Grosphus grandidieri. “Toxic” means that the mice showed symptoms such as: pain, piloerection, excitability, salivation, lacrimation, dyspnea, diarrhea, temporary paralysis, but recovered within 20 h. “Lethal” means that the mice showed some or all the symptoms of intoxication and died within 20 h after injection. -
Caracterização Proteometabolômica Dos Componentes Da Teia Da Aranha Nephila Clavipes Utilizados Na Estratégia De Captura De Presas
UNIVERSIDADE ESTADUAL PAULISTA “JÚLIO DE MESQUITA FILHO” INSTITUTO DE BIOCIÊNCIAS – RIO CLARO PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS BIOLÓGICAS BIOLOGIA CELULAR E MOLECULAR Caracterização proteometabolômica dos componentes da teia da aranha Nephila clavipes utilizados na estratégia de captura de presas Franciele Grego Esteves Dissertação apresentada ao Instituto de Biociências do Câmpus de Rio . Claro, Universidade Estadual Paulista, como parte dos requisitos para obtenção do título de Mestre em Biologia Celular e Molecular. Rio Claro São Paulo - Brasil Março/2017 FRANCIELE GREGO ESTEVES CARACTERIZAÇÃO PROTEOMETABOLÔMICA DOS COMPONENTES DA TEIA DA ARANHA Nephila clavipes UTILIZADOS NA ESTRATÉGIA DE CAPTURA DE PRESA Orientador: Prof. Dr. Mario Sergio Palma Co-Orientador: Dr. José Roberto Aparecido dos Santos-Pinto Dissertação apresentada ao Instituto de Biociências da Universidade Estadual Paulista “Júlio de Mesquita Filho” - Campus de Rio Claro-SP, como parte dos requisitos para obtenção do título de Mestre em Biologia Celular e Molecular. Rio Claro 2017 595.44 Esteves, Franciele Grego E79c Caracterização proteometabolômica dos componentes da teia da aranha Nephila clavipes utilizados na estratégia de captura de presas / Franciele Grego Esteves. - Rio Claro, 2017 221 f. : il., figs., gráfs., tabs., fots. Dissertação (mestrado) - Universidade Estadual Paulista, Instituto de Biociências de Rio Claro Orientador: Mario Sergio Palma Coorientador: José Roberto Aparecido dos Santos-Pinto 1. Aracnídeo. 2. Seda de aranha. 3. Glândulas de seda. 4. Toxinas. 5. Abordagem proteômica shotgun. 6. Abordagem metabolômica. I. Título. Ficha Catalográfica elaborada pela STATI - Biblioteca da UNESP Campus de Rio Claro/SP Dedico esse trabalho à minha família e aos meus amigos. Agradecimentos AGRADECIMENTOS Agradeço a Deus primeiramente por me fortalecer no dia a dia, por me capacitar a enfrentar os obstáculos e momentos difíceis da vida. -
Anticoagulant Activity of Low-Molecular Weight Compounds from Heterometrus Laoticus Scorpion Venom
toxins Article Anticoagulant Activity of Low-Molecular Weight Compounds from Heterometrus laoticus Scorpion Venom Thien Vu Tran 1,2, Anh Ngoc Hoang 1, Trang Thuy Thi Nguyen 3, Trung Van Phung 4, Khoa Cuu Nguyen 1, Alexey V. Osipov 5, Igor A. Ivanov 5, Victor I. Tsetlin 5 and Yuri N. Utkin 5,* ID 1 Institute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City 700000, Vietnam; [email protected] (T.V.T.); [email protected] (A.N.H.); [email protected] (K.C.N.) 2 Vietnam Academy of Science and Technology, Graduate University of Science and Technology, Ho Chi Minh City 700000, Vietnam 3 Faculty of Pharmacy, Nguyen Tat Thanh University, Ho Chi Minh City 700000, Vietnam; [email protected] 4 Istitute of Chemical Technology, Vietnam Academy of Science and Technology, Ho Chi Minh City 700000, Vietnam; [email protected] 5 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia; [email protected] (A.V.O.); [email protected] (I.A.I.); [email protected] (V.I.T.) * Correspondence: [email protected] or [email protected]; Tel.: +7-495-336-6522 Academic Editor: Steve Peigneur Received: 9 September 2017; Accepted: 21 October 2017; Published: 26 October 2017 Abstract: Scorpion venoms are complex polypeptide mixtures, the ion channel blockers and antimicrobial peptides being the best studied components. The coagulopathic properties of scorpion venoms are poorly studied and the data about substances exhibiting these properties are very limited. During research on the Heterometrus laoticus scorpion venom, we have isolated low-molecular compounds with anticoagulant activity. -
Rossi Gf Me Rcla Par.Pdf (1.346Mb)
RESSALVA Atendendo solicitação da autora, o texto completo desta dissertação será disponibilizado somente a partir de 28/02/2021. UNIVERSIDADE ESTADUAL PAULISTA “JÚLIO DE MESQUITA FILHO” Instituto de Biociências – Rio Claro Departamento de Zoologia Giullia de Freitas Rossi Taxonomia e biogeografia de aranhas cavernícolas da infraordem Mygalomorphae RIO CLARO – SP Abril/2019 Giullia de Freitas Rossi Taxonomia e biogeografia de aranhas cavernícolas da infraordem Mygalomorphae Dissertação apresentada ao Departamento de Zoologia do Instituto de Biociências de Rio Claro, como requisito para conclusão de Mestrado do Programa de Pós-Graduação em Zoologia. Orientador: Prof. Dr. José Paulo Leite Guadanucci RIO CLARO – SP Abril/2019 Rossi, Giullia de Freitas R832t Taxonomia e biogeografia de aranhas cavernícolas da infraordem Mygalomorphae / Giullia de Freitas Rossi. -- Rio Claro, 2019 348 f. : il., tabs., fotos, mapas Dissertação (mestrado) - Universidade Estadual Paulista (Unesp), Instituto de Biociências, Rio Claro Orientador: José Paulo Leite Guadanucci 1. Aracnídeo. 2. Ordem Araneae. 3. Sistemática. I. Título. Sistema de geração automática de fichas catalográficas da Unesp. Biblioteca do Instituto de Biociências, Rio Claro. Dados fornecidos pelo autor(a). Essa ficha não pode ser modificada. Dedico este trabalho à minha família. AGRADECIMENTOS Agradeço ao meus pais, Érica e José Leandro, ao meu irmão Pedro, minha tia Jerusa e minha avó Beth pelo apoio emocional não só nesses dois anos de mestrado, mas durante toda a minha vida. À José Paulo Leite Guadanucci, que aceitou ser meu orientador, confiou em mim e ensinou tudo o que sei sobre Mygalomorphae. Ao meu grande amigo Roberto Marono, pelos anos de estágio e companheirismo na UNESP Bauru, onde me ensinou sobre aranhas, e ao incentivo em ir adiante. -
Journal of Cave and Karst Studies
March 2018 Volume 80, Number 1 JOURNAL OF ISSN 1090-6924 A Publication of the National CAVE AND KARST Speleological Society STUDIES DEDICATED TO THE ADVANCEMENT OF SCIENCE, EDUCATION, EXPLORATION, AND CONSERVATION Published By BOARD OF EDITORS The National Speleological Society Anthropology George Crothers http://caves.org/pub/journal University of Kentucky Lexington, KY Office [email protected] 6001 Pulaski Pike NW Huntsville, AL 35810 USA Conservation-Life Sciences Tel:256-852-1300 Julian J. Lewis & Salisa L. Lewis Lewis & Associates, LLC. [email protected] Borden, IN [email protected] Editor-in-Chief Earth Sciences Benjamin Schwartz Malcolm S. Field Texas State University National Center of Environmental San Marcos, TX Assessment (8623P) [email protected] Office of Research and Development U.S. Environmental Protection Agency Leslie A. North 1200 Pennsylvania Avenue NW Western Kentucky University Washington, DC 20460-0001 Bowling Green, KY [email protected] 703-347-8601 Voice 703-347-8692 Fax [email protected] Mario Parise University Aldo Moro Production Editor Bari, Italy Scott A. Engel [email protected] Knoxville, TN 225-281-3914 Exploration Paul Burger [email protected] National Park Service Eagle River, Alaska Journal Copy Editor [email protected] Linda Starr Microbiology Albuquerque, NM Kathleen H. Lavoie State University of New York Plattsburgh, NY [email protected] Paleontology Greg McDonald National Park Service Fort Collins, CO [email protected] Social Sciences Joseph C. Douglas The Journal of Cave and Karst Studies , ISSN 1090-6924, CPM Volunteer State Community College Number #40065056, is a multi-disciplinary, refereed journal pub- Gallatin, TN lished four times a year by the National Speleological Society.