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Boston University Photonics Center Annual Report 2018
Boston University Photonics Center Annual Report 2018 Letter from the Director THIS ANNUAL REPORT summarizes activities of the Boston University Photonics Center for the 2017-2018 academic year. In it, you will find quantitative and descriptive information regarding our photonics programs in education, interdisciplinary research, business innovation, and technology development. Located at the heart of Boston University’s urban campus, the Photonics Center is an interdisciplinary hub for education, research, scholarship, innovation, and technology development associated with practical uses of light. Our nine-story building houses world-class research facilities and shared laboratories dedicated to photonics research, and sustains the work of 58 faculty members, 12 staff members, and more than 100 graduate students and postdoctoral fellows. Over the past year, the Center achieved the three main goals of the strategic plan that our community committed itself to nearly six years ago. Our first strategic goal was to strengthen the Center’s research foundation, which we quantified succinctly as sustained grant income of $20M per year by Photonics Center researchers. At the time of our strategic plan, our annual grant income was about half that, and Center operations were substantially leveraged by a single DoD Technology Over the past Translation Contract that ended in 2011. In the years since, we have focused year, the Center our efforts on supporting and catalyzing new research grants by our faculty, and achieved the three the effort has paid off. Our average grant support over the past four years has main goals of the exceeded our target, and this year our grant income was about $21M. -
Advances in Optics for Biotechnology, Medicine and Surgery XV
Program Advances in Optics for Biotechnology, Medicine and Surgery XV July 23 - 26, 2017 Westin Snowmass Snowmass Village, Colorado, USA Conference Chairs Peter So Massachusetts Institute of Technology, USA Kate Bechtel Triple Ring Technologies, USA Ivo Vellekoop University of Twente, The Netherlands Michael Choma Yale University, USA Engineering Conferences International 32 Broadway, Suite 314 - New York, NY 10004, USA www.engconfintl.org – [email protected] The Westin Snowmass Resort 100 Elbert Lane, PO Box 5009 Snowmass Village, Colorado, 81615 United States +1-970-923-8200 Engineering Conferences International (ECI) is a not-for-profit global engineering conferences program, originally established in 1962, that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines. ECI BOARD MEMBERS Barry C. Buckland, President Mike Betenbaugh Nick Clesceri Peter Gray Michael King Raymond McCabe David Robinson Eugene Schaefer P. Somasundaran Chair of ECI Conferences Committee: Nick Clesceri ECI Technical Liaison for this conference: Brian Wilson ECI Executive Director: Barbara K. Hickernell ECI Associate Director: Kevin M. Korpics ©Engineering Conferences International Previous conferences in this series: Future Directions for Lasers in Medicine and Surgery February 26-March 3, 1989 Palm Coast, Florida Conference Chairs: Ronald W. Waynant, FDA, USA Ashley J. Welch, University of Texas-Austin, USA Future Directions for Lasers in Medicine and Surgery II February 24-March 1, 1991 Palm Coast, Florida Conference Chairs: Thomas F. Deutsch, Wellman Labs, MA General, USA Ronald W. Waynant, FDA/CDRH, USA Future Directions for Lasers in Medicine and Surgery III February 27-March 4, 1993 Palm Coast, Florida Conference Chair: Joseph T. -
Short Course 2
SHORT COURSE 2: Functional, Structural, and Molecular Imaging, and Big Data Analysis Organized by Ed Boyden, PhD, and Kwanghun Chung,NEW PhD COVER TK Short Course 2 Functional, Structural, and Molecular Imaging, and Big Data Analysis Organized by Ed Boyden, PhD, and Kwanghun Chung, PhD Please cite articles using the model: [AUTHOR’S LAST NAME, AUTHOR’S FIRST & MIDDLE INITIALS] (2018) [CHAPTER TITLE] Functional, Structural, and Molecular Imaging, and Big Data Analysis. (Boyden E, Chung K, eds) pp. [xx-xx]. Washington, DC : Society for Neuroscience. All articles and their graphics are under the copyright of their respective authors. Cover graphics and design © 2018 Society for Neuroscience. SHORT COURSE 2 Functional, Structural, and Molecular Imaging, and Big Data Analysis Organized by Ed Boyden, PhD, and Kwanghun Chung, PhD Friday, November 2, 2018 8 a.m.–6 p.m. Location: San Diego Convention Center • Room: 6CF TIME TOPIC SPEAKER 7:30–8 a.m. CHECK-IN Ed Boyden, PhD • Massachusetts Institute of Technology 8–8:10 a.m. Opening Remarks Kwanghun Chung, PhD • Massachusetts Institute of Technology Advanced Optical Methods for Multi-Scale Optical Probing and 8:10–8:50 a.m. Valentina Emiliani, PhD • Paris Descartes University Manipulation of Neural Circuits 8:50–9:30 a.m. Optical Imaging of Neural Ensemble Dynamics in Behaving Animals Mark Schnitzer, PhD • Stanford University 9:30–10:10 a.m. High-Resolution and High-Speed In Vivo Imaging of the Brain Na Ji, PhD • University of California, Berkeley 10:10–10:30 a.m. BREAK High-Speed Volumetric Microscopy and Wide-Field Optical 10:30–11:10 a.m. -
Tuesday, May 21, 2019
CME-accredited ICMIC Seminar Series 2003 – 2018 Jerry Glickson, PhD NMR Studies of Lonidamine: Stoll 11/14/18 Professor of Radiology Mechanism of Action and Effects Conference University of Pennsylvania on Melanoma and other Cancers Room David Bonekamp, PhD Professor Radiomics and Deep Learning in Stoll Deutsches 11/7/18 Oncology: Examples in Prostate, Conference Krebsforschungszentrum Brain and Breast Cancer Room German Cancer Research Center Mass Spectrometric Imaging and Zoltan Takats, PhD Stoll In-vivo Mass Spectrometry - A 10/24/18 Professor of Analytical Chemistry Conference New Era in Understanding Tissue Imperial College of London Room Biology Elizabeth Hillman, PhD Capturing Dynamic Brain and Stoll Professor of Biomedical Tissue Function with High-speed, 10/17/18 Conference Engineering Multi-scale Optical Imaging and Room Columbia University Microscopy Norma Kanarek, PhD, MPH Stoll Big Picture Cancer Prevention 9/26/18 Associate Professor Conference and Control JHU JHBSPH & SKCCC Room Sridhar Nimmagadda, PhD A non-invasive Tool to Quantify Stoll 08/29/18 Associate Professor the Activity of PD-L1 Therapeutics Conference JHU Dept. of Radiology at the Tumor Room Sanjay Jain, M.D. Stoll Professor Imaging of Infections: Bench to 07/25/18 Conference JHU Dept. of Pediatric Infectious Bedside Room Disease Nimmi Ramanujam, PhD Robert Carr Jr. Professor of Innovations to Accelerate Stoll Biomedical Engineering 5/9/18 Improved Access across the Conference Professor of Pharmacology & Cancer Care Continuum Room Cancer Biology Duke University -
Programme Booklet Elwell Web
THEO MURPHY INTERNATIONAL SCIENTIFIC MEETING ON Making light work: illuminating the future of biomedical optics Monday 8 November – Wednesday 10 November 2010 The Kavli Royal Society International Centre, Chicheley Hall, Buckinghamshire Organised by Professor Clare Elwell, Professor Jeremy Hebden, Professor Paul Beard, Professor Elizabeth Hillman and Professor Chris Cooper - Programme and abstracts - Speaker biographies - Notes - Participant list - Publication order form The abstracts that follow are provided by the presenters and the Royal Society takes no responsibility for their content. 2 Making light work: illuminating the future of biomedical optics Monday 8 – Wednesday 10 November 2010 Organised by Professor Clare Elwell, Professor Jeremy Hebden, Professor Paul Beard, Professor Elizabeth Hillman and Professor Chris Cooper Day 1 – Monday 8 November 2010 12.00 Registration and lunch* 13.00 Welcome by Professor Clare Elwell , Organiser Welcome by Professor Sir Peter Knight FRS , Principal, The Kavli Royal Society International Centre SESSION 1 – CURRENT STATUS AND INNOVATIONS IN OPTICAL TECHNOLOGIES Chairs – Professor Joseph Culver, Washington University in St Louis, USA Professor Matthias Kohl-Bareis, University of Applied Sciences Koblenz, Germany 13.15 ‘Near-infrared spectroscopy and imaging of living systems’: from 1996 to 2010 and beyond Professor Clare Elwell, University College London, UK 13.40 Discussion 14.00 Blood flow monitors & other recent developments in diffuse optics Professor Arjun Yodh, University of Pennsylvania, -
A Picosecond Optoelectronic Cross Correlator Using a Gain Modulated Avalanche Photodiode for Measuring the Impulse Response of Tissue
A Picosecond Optoelectronic Cross Correlator using a Gain Modulated Avalanche Photodiode for Measuring the Impulse Response of Tissue. David R. Kirkby B.Sc. M.Sc. Department of Medical Physics and Bioengineering, University College London. Thesis submitted for the degree of Doctor of Philosophy (Ph.D.) at the University of London. Supervisor: Professor David T. Delpy, FRS. Second supervisor: Dr. Mark Cope. April 1999. 2 Abstract Human tissue is relatively transparent to light between 700 and 1000 nm in the near infra- red (NIR). NIR spectroscopy is a technique that can measure non-invasively and safely, the optical properties of tissue. Several different types of spectroscopic instrumentation have currently been developed, ranging from simple continuous intensity systems, through to complex time and frequency resolved techniques. This thesis describes the development of a near infra-red time-resolved system, using an inexpensive avalanche photodiode (APD) detector and a microwave step recovery diode (SRD) in a novel way to implement a totally electronic cross- correlator, with no moving parts. The aim of the work was to develop a simple instrument to monitor scattering changes in tissue during laser induced thermal therapy. The APD was gain-modulated by rapidly varying the bias voltage using electrical pulses generated by the SRD (120 ps full width half maximum (FWHM) and8Vinamplitude). The resulting cross-correlator had a temporal resolution of 275 ps FWHM - significantly faster than the 750 ps FWHM of the APD when operating with a conventional fixed bias voltage. Spurious responses caused by the SRD were observed, which were removed by the addition of Schottky diodes on the SRD’s output, although this slightly degraded the system temporal resolution from 275 to 380 ps FWHM. -
Core Faculty
CORE FACULTY Elham Azizi Elham Azizi utilizes an interdisciplinary approach combining cutting-edge single-cell Assistant Professor, Biomedical Engineering; Herbert genomic technologies with statistical machine learning techniques, to characterize & Florence Irving Assistant Professor of Cancer complex populations of interacting cells in the tumor microenvironment as well as Data Research (in the Herbert and Florence Irving their dysregulated circuitry. Elham was a postdoctoral fellow at the Memorial Sloan Institute for Cancer Dynamics and in the Herbert Irving Kettering Cancer Center and Columbia University (2014-2019). She received a PhD in Comprehensive Cancer Center) Bioinformatics from Boston University (2014), an MS degree in Electrical Engineering also from Boston University (2010) and a BS in Electrical Engineering from Sharif Machine learning in single cell analysis and cancer. University of Technology (2008). She is a recipient of the NIH NCI Pathway to Independence Award, the Tri-Institutional Breakout Prize for Junior Investigators, and an American Cancer Society Postdoctoral Fellowship. She joined the faculty of Columbia Biomedical Engineering and the Herbert and Florence Irving Institute for Cancer Dynamics in January 2020. Tal Danino Tal Danino’s research explores the emerging field of synthetic biology, focusing on Associate Professor, Biomedical Engineering; engineering bacteria gene circuits to create novel behaviors that have biomedical Director, Synthetic Biological Systems Laboratory applications. The interaction of microbes and tumors is a major target of his work, where DNA sequences and synthetic biology approaches are used to program Synthetic biology. Engineering gene circuits in microbes. bacteria as diagnostics and therapeutics in cancer. Danino also brings this science outside the laboratory as a TED Fellow and through science-art projects. -
Innovations in High Contrast, High Resolution Imaging Technologies
REGIONAL MEETING 1 APRIL 2020 1:00 - 5:00 P.M. Innovations in High Contrast, High Resolution Imaging Technologies MEETING HOSTS ALTON D. ROMIG, JR. Executive Officer, National Academy of Engineering S Alton D. Romig, Jr. is the executive officer of the National Academy of Engineering. Under Congressional charter, the Academy provides advice to the federal government, when requested, on matters of engineering and technology. As T executive officer, Dr. Romig is the chief operating officer responsible for the program, financial, and membership operations of the Academy, reporting to the NAE president. S He was previously vice president and general manager of Lockheed Martin Aeronautics Company Advanced Development Programs, better known as the Skunk Works®. He spent the majority of his career at Sandia National Laboratories, operated by the Lockheed Martin Corporation, having joined Sandia as a member of the technical staff in 1979 and moved through a succession of R&D management positions leading to his appointment as executive vice president in 2005. He served as deputy laboratories director O and chief operating officer until 2010, when he transferred to the Skunk Works. Dr. Romig serves or has served on a number of Advisory Committees including those at Univ of Washington, MIT, Ohio State, Purdue, Georgia Tech, the Colorado School of Mines and Sandia National Laboratories. He is also visiting Associate of Applied Physics and Materials Science at Cal Tech. Dr. Romig H is a member of the Board of Directors of Football Research, Inc., a non-profit entity created and supported by the National Football League to review engineering technology to improve the safety of the sport. -
Advances in Optics for Biotechnology, Medicine and Surgery XI Clinical Challenges and Research Solutions
Program Advances in Optics for Biotechnology, Medicine and Surgery XI Clinical Challenges and Research Solutions June 28 - July 2, 2009 Burlington, Vermont, USA Conference Co-chairs: Stephen A. Boppart University of Illinois at Urbana-Champaign, USA Jeremy C. Hebden University College London, UK Laura Marcu University of California, Davis, USA Engineering Conferences International 32 Broadway, Suite 314 New York, NY 10004, USA Phone: 1-212-514-6760, Fax: 1-212-514-6030 www.engconfintl.org – [email protected] Engineering Conferences International (ECI) is a not-for-profit global engineering conferences program, originally established in 1962, that provides opportunities for the exploration of problems and issues of concern to engineers and scientists from many disciplines. ECI BOARD MEMBERS Barry C. Buckland, President Peter Gray Allen I. Laskin Raymond McCabe David Robinson Jules Routbort William Sachs Eugene Schaefer P. Somasundaran Chair of ECI Conferences Committee: William Sachs ECI Technical Liaison for this conference: Richard Fein ECI Director: Barbara K. Hickernell ECI Associate Director: Kevin M. Korpics ©Engineering Conferences International Conference Sponsors This work has been supported by funding from the National Science Foundation. The Center for Biophotonics, an NSF Science and Technology Center, is managed by the University of California, Davis, under Cooperative Agreement No. PHY 0120999. Sunday, June 28, 2009 16:00 – 18:00 Conference check-in 18:00 – 19:30 Dinner Special Session A: International Perspectives on -
Ripe Opportunities for Regional Collaboration in East Asia
26 July 2001 Nature 412: 6845 (2001) © Macmillan Publishers Ltd. Ripe opportunities for regional collaboration in east 361 Asia East Asian collaboration in molecular biology could enhance the scientific viability of the region, but it requires more enthusiastic support from potential participants — particularly Japan. Back from the brink 361 The government's threat to suspend clinical trials at America's largest medical school highlights an impasse over funding. Johns Hopkins researchers fume over government 363 crackdown Drugs approval process gets speed treatment 364 Scientists fear new guidelines will stifle basic research 364 'Political fix' saves Kyoto deal from collapse 365 US rejects bioweapon inspections 365 Author of anti-encryption program faces jail 366 NASA mission has wind in its sails 366 Physicists rally behind linear-collider plan 367 Sea lions massacred in Galapagos for sex organs 367 news in brief 368 Building a biopolis 370 Having established itself as a financial and manufacturing centre, Singapore now wants to become a leading player in advanced biological research. David Cyranoski assesses the scientific ambitions of a vibrant city-state. Picture perfect 372 Medical imaging techniques are being adapted to study gene expression and other cellular activities in living animals. Corie Lok talks to the pioneers who are watching cells at work in their natural habitat. Framework welcome, but could do with fine-tuning 375 Let's get details sorted out, timescales defined, postdocs funded, entrepreneurs trained. Climate-change strategy needs to be robust 375 When three's not a crowd 375 Medicine as performance 377 JOHN HARLEY WARNER reviews Bodies Politic: Disease, Death and Doctors in Britain, 1650–1900 by Roy Porter Early British modern medicine can be considered as a type of theatre. -
HCS Newsletter Spring 2016
The Histochemical Society Newsletter A Message from HCS President Elect, Margarida Barroso Journal of HistochemistryJHCMargarida & Cytochemistry Barroso is President-Elect of The Histochemical Society andAN INTERN anATION AAssociateL CELL BIOLOGY JOURN ALProfessor at the Albany Medical College, Albany, NewVolume York. 64 • Number Her 1 • JaN uarymain 2016 research goal is to accelerate pre-clinical drug discovery by developing novel imaging assays to screen and optimize Podocin Co-Localizing with α-Cateninthe delivery of targeted anti-cancer drugs. Research is focused on in the Chicken Glomerulus the visualization, quantitation and optimization of drug delivery into cancer cells using receptor-targeted approaches. Join or Renew your membership today! Basic cell biology questions such as iron-mediated endosome- mitochondria interactions as well as the organization and regulation NEW FOR 2016 - paid members of the endocytic recycling pathway in human cancer cell lines are also receive complimentary manuscript fees for JHC a major focus of Dr. Barroso’s research. Online subscription to the Journal of Histochemistry & Cytochemistry (print optional for regular and associate members) Official Journal of jhc.sagepub.com The Histochemical Society ISSN: 0022-1554 Eligibility for HCS sponsored meritorious awards for the HCS annual meeting at Experimental Biology and the IHCM course at MBL Opportunity to present papers, exchange ideas, and network with leading researchers in the field at HCS annual meetings Membership in FASEB Reduced registration for Experimental Biology meetings (HCS annual meetings held in Shown here is the mainstay of her research; the endocytic pathway conjunction with EB) as visualized by fluorescently labeled transferrin. The function of Affiliation with the transferrin is to carry iron into the cells via the transferrin receptor, International Federation of which is highly overexpressed in cancer cells. -
Research.Pdf (2.025Mb)
Frequency Domain Fluorescent Molecular Tomography and Molecular Probes for Small Animal Imaging ________________________________________________________________ A Dissertation Presented to The Faculty of the Graduate School University of Missouri, Columbia ________________________________________________________________ In Partial Fulfillment Of the Requirements for the Degree Doctor of Philosophy ________________________________________________________________ By NARESH GANDHI KUJALA Dr. Ping Yu Dissertation Supervisor JULY 2009 The undersigned, appointed by the Dean of the Graduate School, have examined the dissertation write up entitled: Frequency Domain Fluorescent Molecular Tomography and Molecular Probes for Small Animal Imaging Presented by NARESH GANDHI KUJALA A candidate for the degree of Doctor of Philosophy, and hereby certify that, in their opinion, it is worthy of acceptance. ______________________________ Dr. Ping Yu ______________________________ Dr. H. R. Chandrasekhar ______________________________ Dr. Meera Chandrasekhar ______________________________ Dr. Lixin Ma ______________________________ Dr. Shi-Jie Chen Dedicated to my parents: Kujala Narasimha and Bhanumathi Dedicated to my wife, son and daughter: Kujala Siriyala, Saichandra, and Medha ACKNOWLEDGEMENTS I would like to thank my supervisor Dr. Ping Yu, Assistant Professor of Physics and Astronomy, for his support, encouragement and guidance throughout the whole period of my Ph.D. studies. He provided superior guidance, and I have the deepest respect for him. I am forever indebted to him. I learned something new every time I talked with him. It has been a great privilege to know him and his examples have been highly motivating. I am grateful to Dr. Lixin Ma, Assistant Professor in the Department of Radiology, for her help in the development and evaluation of the MRI-Optical imaging of molecular probes. I appreciate her support and suggestions to me.