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Ripe Opportunities for Regional Collaboration in East Asia 26 July 2001 Nature 412: 6845 (2001) © Macmillan Publishers Ltd. Ripe opportunities for regional collaboration in east 361 Asia East Asian collaboration in molecular biology could enhance the scientific viability of the region, but it requires more enthusiastic support from potential participants — particularly Japan. Back from the brink 361 The government's threat to suspend clinical trials at America's largest medical school highlights an impasse over funding. Johns Hopkins researchers fume over government 363 crackdown Drugs approval process gets speed treatment 364 Scientists fear new guidelines will stifle basic research 364 'Political fix' saves Kyoto deal from collapse 365 US rejects bioweapon inspections 365 Author of anti-encryption program faces jail 366 NASA mission has wind in its sails 366 Physicists rally behind linear-collider plan 367 Sea lions massacred in Galapagos for sex organs 367 news in brief 368 Building a biopolis 370 Having established itself as a financial and manufacturing centre, Singapore now wants to become a leading player in advanced biological research. David Cyranoski assesses the scientific ambitions of a vibrant city-state. Picture perfect 372 Medical imaging techniques are being adapted to study gene expression and other cellular activities in living animals. Corie Lok talks to the pioneers who are watching cells at work in their natural habitat. Framework welcome, but could do with fine-tuning 375 Let's get details sorted out, timescales defined, postdocs funded, entrepreneurs trained. Climate-change strategy needs to be robust 375 When three's not a crowd 375 Medicine as performance 377 JOHN HARLEY WARNER reviews Bodies Politic: Disease, Death and Doctors in Britain, 1650–1900 by Roy Porter Early British modern medicine can be considered as a type of theatre. The director's tale 378 SUSAN WRIGHT reviews The Recombinant DNA Controversy: A Memoir. Science, Politics and the Public Interest 1974–1981 by Donald S. Fredrickson Mitigating mutations 379 ANDREW BERRY reviews The Cooperative Gene: How Mendel's Demon Explains the Evolution of Complex Beings/Mendel's Demon: Gene Justice and the Complexity of Life by Mark Ridley To begin at the beginning 380 SEAN J. MORRISON reviews Stem Cell Biology edited by Daniel R. Marshak, Richard L. Gardner and David Gottlieb Through the eye of the camera? 380 Reactions of a chemical nature 381 GEORGES BRAM reviews Nationalizing Science: Adolphe Wurtz and the Battle for French Chemistry by Alan J. Rocke Science in culture 382 MARTIN KEMP Celebrating science 383 JOHN CARMODY Scientists feel passion, but they need to convey it in their writing, too. Ultradivided matter 385 PIERRE-GILLES DE GENNES Caught in the crossflow 387 ELIZABETH L. BRAINERD Suspension-feeding fishes filter water through complex structures in their throats. Food particles could clog the filters, but the fishes have a cunning system to prevent that happening. Chemistry: How green was my ester 388 GIORGIO STRUKUL Hydrogen peroxide is an ideal oxidant. It cannot yet be used widely, because viable catalysts aren't available for many industrially important processes. But there are encouraging indications of progress. Neurobiology: Feeling bumps and holes 389 J. RANDALL FLANAGAN AND SUSAN J. LEDERMAN We use our hands as well as our eyes to perceive physical objects. New insight into how our hands feel a surface may have implications for developing virtual-reality tools such as training devices for surgeons. Condensed-matter physics: In search of soft solutions 391 DOUGLAS DURIAN AND HAIM DIAMANT Physicists are turning their attention to delicate forms of matter, some of which appear mundane, but all of which are hard to understand. Fortunately, different materials share similar properties and problems. Chemistry: Rings of destruction 392 TOMAS GANZ Many organisms use natural peptides to ward off microbes, but it's proved hard to make similar molecules for medical use. A ring-shaped peptide that might puncture microbial membranes could be the way forward. Dyslexia: Talk of two theories 393 FRANCK RAMUS One possible reason why people with dyslexia have problems in learning to read is that some neuronal pathways involved in vision and hearing are damaged. That theory may need to be revised. Planetary science: Uncool Callisto 395 KRISTIN A. BENNETT Models of heat convection suggested that any liquid on Callisto, one of Jupiter's moons, must be frozen. But those models did not take into account the different properties a surface layer of ice might have. Population ecology: Birds in a buffer state 396 RORY HOWLETT The Icelandic population of black-tailed godwits, which winter in Britain, has been increasing, so poor British estuarine habitats must be used as well as good ones. This might provide a mechanism for population control. 100 and 50 years ago 394 Daedalus: Deft definitions 396 DAVID JONES This week, Daedalus embarks on an exploration of human emotions. After correlating maps of volunteers' brain activity with how the volunteers say they feel, Daedalus will be able to educate the emotionally confused as to their true state of mind. Chemistry beyond the molecule 397 GAUTAM R. DESIRAJU Supramolecular chemistry has grown in importance because it goes beyond the molecule — the focus of classical chemistry. It also offers a fresh interface with biological and materials science. Persistence of visual memory for scenes 401 DAVID MELCHER A medium-term memory may help us to keep track of objects during visual tasks. Bone histology: Evolution of growth pattern in birds 402 ANUSUYA CHINSAMY AND ANDRZEJ ELZANOWSKI Seed dispersal: Directed deterrence by capsaicin in 403 chillies JOSHUA J. TEWKSBURY AND GARY P. NABHAN Nanostructure: Epitaxial diamond polytypes on silicon 404 Y. LIFSHITZ, X. F. DUAN, N. G. SHANG, Q. LI, L. WAN, I. BELLO & S. T. LEE Dinosaurian growth rates and bird origins 405 KEVIN PADIAN, ARMAND J. DE RICQLÈS & JOHN R. HORNER The stability against freezing of an internal 409 liquid-water ocean in Callisto JAVIER RUIZ Evidence for recent climate change on Mars from the 411 identification of youthful near-surface ground ice JOHN F. MUSTARD, CHRISTOPHER D. COOPER & MOSES K. RIFKIN In situ detection of collisionless reconnection in the 414 Earth's magnetotail M. ØIEROSET, T. D. PHAN, M. FUJIMOTO, R. P. LIN & R. P. LEPPING Quantum-enhanced positioning and clock 417 synchronization VITTORIO GIOVANNETTI, SETH LLOYD & LORENZO MACCONE 420 Diamagnetic activity above Tc as a precursor to superconductivity in La2-xSrxCuO4 thin films IENARI IGUCHI, TETSUJI YAMAGUCHI & AKIRA SUGIMOTO Sn-zeolite beta as a heterogeneous chemoselective 423 catalyst for Baeyer–Villiger oxidations AVELINO CORMA, LASZLO T. NEMETH, MICHAEL RENZ & SUSANA VALENCIA Warm tropical ocean surface and global anoxia during 425 the mid-Cretaceous period PAUL A. WILSON AND RICHARD D. NORRIS Dinosaurian growth patterns and rapid avian growth 429 rates GREGORY M. ERICKSON, KRISTINA CURRY ROGERS & SCOTT A. YERBY Mealybug -proteobacterial endosymbionts contain 433 -proteobacterial symbionts CAROL D. VON DOHLEN, SHAWN KOHLER, SKYLAR T. ALSOP & WILLIAM R. MCMANUS The buffer effect and large-scale population regulation 436 in migratory birds JENNIFER A. GILL, KEN NORRIS, PETER M. POTTS, TÓMAS GRÉTAR GUNNARSSON, PHILIP W. ATKINSON & WILLIAM J. SUTHERLAND Crossflow filtration in suspension-feeding fishes 439 S. LAURIE SANDERSON, ANGELA Y. CHEER, JENNIFER S. GOODRICH, JENNY D. GRAZIANO & W. TODD CALLAN Natural conjugative plasmids induce bacterial biofilm 442 development JEAN-MARC GHIGO Force can overcome object geometry in the perception 445 of shape through active touch GABRIEL ROBLES-DE-LA-TORRE AND VINCENT HAYWARD Ubiquitination-dependent mechanisms regulate 449 synaptic growth and function AARON DIANTONIO, ALI P. HAGHIGHI, SCOTT L. PORTMAN, JASON D. LEE, ANDREW M. AMARANTO & COREY S. GOODMAN Antibacterial agents based on the cyclic D,L- 452 -peptide architecture SARA FERNANDEZ-LOPEZ, HUI-SUN KIM, ELLEN C. CHOI, MERCEDES DELGADO, JUAN R. GRANJA, ALISHER KHASANOV, KARIN KRAEHENBUEHL, GEORGINA LONG, DANA A. WEINBERGER, KEITH M. WILCOXEN & M. REZA GHADIRI RPA governs endonuclease switching during processing 456 of Okazaki fragments in eukaryotes SUNG-HO BAE, KWANG-HEE BAE, JUNG-AE KIM & YEON-SOO SEO 26 July 2001 Volume 412 Issue no 6845 Ripe opportunities for regional collaboration in east Asia East Asian collaboration in molecular biology could enhance the scientific viability of the region, but it requires more enthusiastic support from potential participants — particularly Japan. espite the flowering of scientific excellence in many east Asian between participant nations. Both EMBO and CERN, the European countries in recent years, researchers in that part of the world particle physics laboratory, were set up without relying on the European Din search of collaborators are often inclined to look right past Union or its predecessor organizations. each other to colleagues in the United States or Europe. The tendency The key challenge for IBMN is to obtain commitments from the persists despite the geographical convenience of local collaboration, strongest nations in the region — Japan, Australia and Singapore — in the common scientific and cultural heritage of the region, and the order to build the project’s momentum. Global experience suggests knowledge that major institutions in the United States, in particular, that collaboration cannot occur without top-level political commit- are liable to treat collaborators from abroad as junior partners.
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