DOCSLIB.ORG

OICR Strategic Plan 2010-2015 Was Generated in Parallel with the Pan-Canadian Cancer Research Strategy 2010-2014 and the National Breast Cancer Research Framework

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
OICR Strategic Plan 2010-2015 Was Generated in Parallel with the Pan-Canadian Cancer Research Strategy 2010-2014 and the National Breast Cancer Research Framework Strategic Plan 2010-2015 OICR timeline from 2000 to 2010 The Government of The Government of Ontario Ontario asked Dr. Cabinet approved created the Ontario Cancer OCRN’s board of Calvin Stiller to lead a the Stiller Committee Research Network (OCRN), a directors held its group to recommend recommendation to three-year initiative with three OCRN was first meeting. how a $50 million focus on translational components: The Government of incorporated Mr. George Glover investment in cancer research related to Cancer Research Fund Ontario hired as a federal was appointed the research could have development of new Virtual Information Network Dr. Robert Phillips to not-for-profit first chair of the the greatest impact. cancer therapies. Tumour Bank Network. set up and run OCRN. corporation. board of directors. 05 . 2000 12 . 2000 11 . 2001 09 . 2000 09 . 2001 01 . 2002 Dr. Bette Stephenson The Ontario Innovation Trust provided The Government of Ontario Drs. funding to explore what it would announced it would spend Stephenson The Government of take for Ontario to make a significant $1 billion over 10 years to and Stiller The Cancer Ontario announced impact on cancer; Mr. George Connell, create a cancer research Dr. John Evans submitted Research $50 million in Dr. Louis Siminovitch, Dr. Charles institute; Drs. Bette was appointed their report Fund held additional funding for Hollenberg, Ms. Michele Noble and Stephenson and Calvin Stiller chair of OCRN’s to the its first grant OCRN, extending its Dr. Patrick Lafferty began work on a were asked to spearhead the board of Government competition. mandate to four years. proposal. development of the institute. directors. of Ontario. 05. 2002 07 . 2002 10 . 2003 06 . 2002 03 . 2003 01 . 2004 OCRN’s board of directors was expanded to include Dr. Elizabeth Eisenhauer Dr. Phillip Sharp The Government representatives of the University OICR appointed Dr. Elizabeth Eisenhauer, of Ontario Health Network (UHN) (Princess Director, Investigational New Drug Program OICR’s board announced its Margaret Hospital), Cancer Ontario Premier Dalton NCIC Clinical Trials Group, Professor, Department of directors intent to create Care Ontario, the Council of McGuinty announced the of Oncology, Queen’s University and Co-Chair began a a new cancer Ontario Universities and the launch of the Ontario Institute Canadian Cancer Research Alliance and Dr. Phillip search for research institute Council of Academic Hospitals for Cancer Research (OICR) Sharp, Institute Professor, Center for Cancer the founding and asked OCRN of Ontario. It became the at a news conference at the Research, Massachusetts Institute of Technology, President to evolve into the founding board of directors of Hospital for Sick Children as co-chairs of, as well as seven members to, its and Scientific new institute. the new institute. in Toronto. Scientific Advisory Board (SAB). Director. 05. 2005 12. 2005 01. 2006 06 . 2005 12 . 2005 The Ministry of Research OICR joined the RNAi and Innovation Consortium based at the approved OICR’s Broad Institute of Harvard strategic plan. and MIT. The Consortium Dr. Hudson began The SAB will create research The Premier of Ontario consultation held its first 02. 2007 reagents consisting of announced the creation of the Dr. Tom Hudson was with the Ontario meeting specific RNAi inhibitors Cancer Stem Cell Consortium appointed President cancer research and Dr. Robert targeting human and at an event at MaRS with and Scientific Director. community and discussed Sutherland was mouse genes which will California Governor Arnold Dr. Phillips was external experts to strategic appointed be used to discover key Schwarzenegger. He also appointed Deputy develop a strategic directions Vice-President, genes underlying normal announced $30 million in Director. research plan. for OICR. Commercialization. physiology and disease. funding for this initiative. 07. 2006 03. 2007 05 . 2007 06 . 2006 09 . 2006 04 . 2007 OICR invested in five signature initiatives: OICR contributed funding Cancer Stem Cell OICR launched for the creation of the Centre Program ($17 million); the Intellectual for Probe Development and One Millimetre Cancer Property Commercialization (CPDC), Challenge ($12.5 million); Development and a Centre of Excellence for OICR awarded Imaging Pipeline Commercialization The Terry Fox Foundation Commercialization and Research, up to $500,000 Platform ($10 million); Program (IPDCP) announced the creation of the funded by the federal Networks each to four Cancer Research Fund to facilitate the Terry Fox Research Institute of Centres of Excellence. The recipients to ($8.7 million); and state- development and (TFRI). The TFRI established CPDC is the world’s first facility OICR hosted continue the of-the-art equipment in commercialization nodes across Canada and focusing on all areas related to its first Annual early commercial 11 research institutions of cancer-related launched the Ontario node in the development of molecular Scientific development of across Ontario discoveries. partnership with OICR. imaging probes. Meeting. their discoveries. ($9.8 million). 10. 2007 02. 2008 07 . 2007 02 . 2008 04 . 2008 04 . 2008 The Canadian Partnership Against Cancer (CPAC) announced the launch of The Canadian OICR invested The Premier of Ontario announced Partnership for Tomorrow Project with $42 $500,000 in DVS the launch of the International Cancer million in funding. The Project will study 300,000 Sciences Inc., for a Genome Consortium (ICGC) at a Canadians to explore how genetics, environment, novel technology news conference at MaRS. OICR was lifestyle and behaviours contribute to the OICR and the TFRI to facilitate the selected by the Consortium to house development of cancer. OICR is a partner in launched the Selective identification of the Data Coordination Centre and the project; its Ontario Health Study will follow Therapies Target biomarkers to study host the Secretariat for the ICGC. 150,000 people in Ontario for 20 years. Identification Program. and diagnose cancer. 06. 2008 07 . 2008 04 . 2008 06 . 2008 GE Healthcare announced that The Premier of Ontario OICR received Hamilton is the first site in the announced funding of $12.5 million world to receive new prototype $10 million through OICR from the Canada technologies for molecular breast OICR invested for the Ontario Regional Foundation The ICGC announced imaging research because of the $2.25 million in Biotherapeutics Program for Innovation the launch of eight strong research partnerships among five promising (ORBiT) to develop to support the cancer genome OICR-funded scientists at the early stage cancer therapies based on cells, Pancreatic Cancer projects by 11 Dr. Stiller was Centre for Probe Development and technologies genes and viruses, which Genome Project funding organizations. appointed Commercialization and the oncology to continue the can be programmed to and the Data Ontario scientists chair of OICR’s and nuclear medicine programs at early commercial target diseased tissue Coordination are sequencing board of McMaster University and Hamilton development of without harming normal Centre for the ICGC. pancreatic cancer. directors. Health Sciences. these discoveries. tissue. 01. 2009 04. 2009 06. 2009 11 . 2008 01. 2009 06 . 2009 Pfizer Global Research and Development announced an investment of $6 million in the POP-CURE Project, a partnership of Pfizer, OICR, and the Ontario Cancer Dr. Nicole Onetto Dr. Eric Lander Institute, the research arm of UHN’s Dr. Phillips retired as Deputy Director Princess Margaret Hospital. POP-CURE of OICR and Dr. Nicole Onetto was will discover and validate new targets for appointed Deputy Director. Dr. Sharp Mr. Frank Stonebanks the diagnosis, prognosis and treatment resigned as co-chair of the SAB. Dr. Sutherland retired as Vice- of colorectal cancer. The Government Dr. Eric Lander, President and Founding President, Commercialization and of Ontario awarded $900,000 to Pfizer Director of the Broad Institute of MIT Mr. Frank Stonebanks was appointed through its Biopharmaceutical Investment and Harvard was appointed co-chair of Vice-President, Commercialization Program for the POP-CURE project. the SAB (with Dr. Eisenhauer). and Chief Commercial Officer. 11. 2009 07 . 2009 02 . 2010 Table of Contents Background.......................................................................................... 5 Grand Challenges in Cancer Research....................................................... 9 Accelerating Translation – OICR’s Translation Priorities............................... 10 Innovation Programs.............................................................................. 23 Technology Platforms............................................................................. 26 Translation Programs............................................................................. 29 Other OICR Initiatives............................................................................ 32 Conclusion............................................................................................ 33 OICR Leaders........................................................................................ 34 Board of Directors.................................................................................. 38 Scientific Advisory Board......................................................................... 39 Background Vision The Ontario Institute for Cancer Research (OICR), launched December 2, 2005, is a new centre of excellence that is moving the province
Load more

Recommended publications
  • C. Elegans Whole Genome Sequencing Reveals Mutational Signatures Related to Carcinogens and DNA Repair Deficiency
    Downloaded from genome.cshlp.org on September 28, 2021 - Published by Cold Spring Harbor Laboratory Press C. elegans whole genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency Authors: Bettina Meier * (1); Susanna L Cooke * (2); Joerg Weiss (1); Aymeric P Bailly (1,3); Ludmil B Alexandrov (2); John Marshall (2); Keiran Raine (2); Mark Maddison (2); Elizabeth Anderson (2); Michael R Stratton (2); Anton Gartner * (1); Peter J Campbell * (2,4,5). * These authors contributed equally to this project. Institutions: (1) Centre for Gene Regulation and Expression, University of Dundee, Dundee, UK. (2) Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. (3) CRBM/CNRS UMR5237, University of Montpellier, Montpellier, France. (4) Department of Haematology, University of Cambridge, Cambridge, UK. (5) Department of Haematology, Addenbrooke’s Hospital, Cambridge, UK. Address for correspondence: Dr Peter J Campbell, Dr Anton Gartner, Cancer Genome Project, Centre for Gene Regulation and Expression, Wellcome Trust Sanger Institute, The University of Dundee, Hinxton CB10 1SA, Dow Street, Cambridgeshire, Dundee DD1 5EH UK. UK. Tel: +44 (0) 1223 494745 Phone: +44 (0) 1382 385809 Fax: +44 (0) 1223 494809 E-mail: [email protected] E-mail: [email protected] Running title: mutation profiling in C. elegans Keywords: mutation pattern, genetic and environmental factors, C. elegans, cisplatin, aflatoxin B1, whole-genome sequencing. Downloaded from genome.cshlp.org on September 28, 2021 - Published by Cold Spring Harbor Laboratory Press ABSTRACT Mutation is associated with developmental and hereditary disorders, ageing and cancer. While we understand some mutational processes operative in human disease, most remain mysterious.
    [Show full text]
  • Abstracts In
    ECCB 2014 Accepted Posters with Abstracts G: Bioinformatics of health and disease G01: Emile Rugamika Chimusa, Jacquiline Wangui Mugo and Nicola Mulder. Leveraging ancestry along the genome of admixed individuals to resolve missing heritability in disease scoring statistics Abstract: Human genetics has been haunted by the mystery of “missing heritability” of common traits. Although studies have discovered several variants associated with common diseases and traits, these variants typically appear to explain only a minority of the heritability. Resolving missing heritability, the difference between phenotypic variance explained by associated SNPs and estimates of narrow-sense heritability (h2), will inform strategies for disease mapping and prediction of complex traits. Among biased estimates of h2 due to epistatic interactions and rare variants not captured by genotyping arrays have been cited to be the most can be the most explanations for missing heritability. Here, we present an approach for estimating heritability of traits based on sharing local ancestry segments between pairs of unrelated individuals in an admixed population. From simulation data and real data, we demonstrated that our approach outperformed current approaches for estimating heritability of traits and holds values in admixture mapping for deconvoluting genes underlying ethnic differences in complex diseases risk. G02: Sylvain Mareschal, Pierre-Julien Viailly, Philippe Bertrand, Fabienne Desmots-Loyer, Elodie Bohers, Catherine Maingonnat, Karen Leroy, Thierry Fest and Fabrice Jardin. Next- Generation Sequencing applied to tailor targeted therapies in lymphoma: the RELYSE project Abstract: Non-Hodgkin Lymphomas (NHL) are lymphoid cell malignancies accounting for about 4% of all cancers, with an incidence rate of 12 cases per 100,000 and per year in Europe.
    [Show full text]
  • Canada Scientific Advisory Committee (CSAC)
    Canada Scientific Advisory Committee (CSAC) Alan Bernstein, PhD – Co-chairperson Canadian Institute for Advanced Research Toronto, Ontario Alan Bernstein is President of the Canadian Institute for Advanced Research (CIFAR), Canada’s global research institute. From 2008- 2011, Bernstein was the executive director of the Global HIV Vaccine Enterprise, an international alliance of researchers and funders charged with accelerating the search for an HIV vaccine. Previously, he served as the founding president of the Canadian Institutes of Health Research (2000-2007), Canada’s federal agency for the support of health research. In that capacity, he led the transformation of health research in Canada. After receiving his PhD from the University of Toronto, and following postdoctoral work in London, Bernstein joined the Ontario Cancer Institute (1974-1985). In 1985, he joined the new Samuel Lunenfeld Research Institute in Toronto, was named Associate Director in 1988 and then Director of Research (1994-2000). Internationally known for his contributions to our understanding of the molecular basis of cancer, Bernstein has made extensive contributions to the study of stem cells, hematopoiesis and cancer. He chairs or is a member of advisory and review boards in Canada, the US, UK and Italy. Bernstein has received numerous awards and honourary degrees for his contributions to science, including the 2008 Gairdner Wightman Award, induction into the Canadian Medical Hall of Fame, and the Henry G. Friesen International Prize in Health Research. He is a Senior Research Fellow of Massey College, received the Order of Ontario in 2018 and was appointed an Officer of the Order of Canada in 2002.
    [Show full text]
  • ANNUAL REPORT 2015/2016 Message from the Minister of Research, Innovation and Science
    ANNUAL REPORT 2015/2016 Message from the Minister of Research, Innovation and Science On behalf of the Government of Ontario I am pleased to have the opportunity to extend my thanks to the Ontario Institute for Cancer Research (OICR) for another successful year in its progress to meet the cancer challenge. A report issued recently by Cancer Care Ontario tells us that one in two Ontarians will develop cancer in their lifetime and cancer is the leading cause of death in the province. We have to do everything possible to alleviate the burden of cancer on Ontario families by improving the prevention, detection, diagnosis and treatment of cancer. We are proud of our investment in OICR over the last 10 years and recently approved the Institute’s Strategic Plan for 2016-2021. OICR has demonstrated leadership in the cancer community not only in its research programs but also in its focus on moving discoveries into the clinic. An example is the development of a novel oncolytic viral immunotherapy which is now in clinical trials. Through OICR’s commercialization partner, the Fight Against Cancer Innovation Trust, financial and in-kind support are attracted which makes it possible to accelerate development and therefore bring new hope to patients. The past year has been one of accomplishment and one of transition. Dr. Calvin Stiller, who was instrumental in the creation of the Institute, has stepped down as Chair of the Board of Directors. We are most grateful for his vision and leadership. Dr. Tom Hudson, who built the Institute, attracted talented researchers and launched provincial, national and international initiatives that are helping to make Ontario a world leader in cancer research, has moved on to the next phase of his career.
    [Show full text]
  • Human Genetics: International Projects and Personalized Medicine
    Drug Metabol Pers Ther 2016; 31(1): 3–8 Mini Review Maria Apellaniz-Ruiza, Cristina Gallegoa, Sara Ruiz-Pintoa, Angel Carracedo and Cristina Rodríguez-Antona* Human genetics: international projects and personalized medicine DOI 10.1515/dmpt-2015-0032 Received August 31, 2015; accepted October 19, 2015; previously Introduction published online November 18, 2015 Genetic variation databases describe naturally occur- Abstract: In this article, we present the progress driven ring genetic differences among individuals of the same by the recent technological advances and new revolu- species. This variation, accounting for 0.1% of our DNA tionary massive sequencing technologies in the field of [1], permits the flexibility and survival of a population human genetics. We discuss this knowledge in relation in the face of changing environmental circumstances, with drug response prediction, from the germline genetic but it also influences how people differ in their risk of variation compiled in the 1000 Genomes Project or in the disease or their response to drugs. It is well known that Genotype-Tissue Expression project, to the phenome- variability in response to drug therapy is the rule rather genome archives, the international cancer projects, such than the exception for most drugs, and these differences as The Cancer Genome Atlas or the International Cancer are among the major challenges in current clinical prac- Genome Consortium, and the epigenetic variation and its tice, drug development, and drug regulation [2, 3]. Thus, influence in gene expression, including the regulation of rather than accepting the “one drug fits all” approach, drug metabolism. This review is based on the lectures pre- researchers envision that drugs need to be tailored to fit sented by the speakers of the Symposium “Human Genet- the profile of each individual patient.
    [Show full text]
  • Princess Margaret Cancer Centre Annual Report
    2 015 A NNU A L REPORT 3 Leadership Message 4 Our Program 4 Who we are Welcome to the 2015 Annual Report for the Princess Margaret Cancer Centre at the University Health Network (UHN). This year proved to be both exciting and engaging as we continue to deliver revolutionary cancer care for our patients, and we are looking 6 Clinical Care forward to sharing the progress we have made. The 2015 edition showcases the recent 6 Our Clinical Programs LEADERSHIP activities and accomplishments of our people, departments, disease groups, and research and education programs. As one of the largest comprehensive cancer treatment facilities in the world, we have a great deal to share as we continue our efforts to be on the 8 Personalized Cancer Medicine MESSAGE frontiers of medical, surgical and radiation oncology, embracing the latest technology 8 Our Strategy and international best-practices, and setting standards for patient care. 9 We Are Transforming Patient Care In 2015, we celebrated 20 years of our presence on University Avenue; the hub of the discovery district. The move not only signified our commitment to meet the increased 11 We Are Augmenting Correlative Cancer Biology demands and evolving needs of our patients, but also encouraged collaboration, innovation, and research, enabling us to continue making progress in conquering cancer. 12 We Are Accelerating Guided Therapeutics Today, we again embrace change as we drive implementation of our space plan, with Marnie Escaf MHA, HBBA 15 We Are Expanding Novel Therapeutics Senior Vice President a focus on redeveloping facilities to improve the patient experience, including patient Executive Lead amenities, access, flow, and wayfinding.
    [Show full text]
  • Strategic Plan 2011-2016
    Strategic Plan 2011-2016 Wellcome Trust Sanger Institute Strategic Plan 2011-2016 Mission The Wellcome Trust Sanger Institute uses genome sequences to advance understanding of the biology of humans and pathogens in order to improve human health. -i- Wellcome Trust Sanger Institute Strategic Plan 2011-2016 - ii - Wellcome Trust Sanger Institute Strategic Plan 2011-2016 CONTENTS Foreword ....................................................................................................................................1 Overview .....................................................................................................................................2 1. History and philosophy ............................................................................................................ 5 2. Organisation of the science ..................................................................................................... 5 3. Developments in the scientific portfolio ................................................................................... 7 4. Summary of the Scientific Programmes 2011 – 2016 .............................................................. 8 4.1 Cancer Genetics and Genomics ................................................................................ 8 4.2 Human Genetics ...................................................................................................... 10 4.3 Pathogen Variation .................................................................................................. 13 4.4 Malaria
    [Show full text]
  • Germline Determinants of the Somatic Mutation Landscape in 2,642 Cancer Genomes
    bioRxiv preprint doi: https://doi.org/10.1101/208330; this version posted November 1, 2017. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Germline determinants of the somatic mutation landscape in 2,642 cancer genomes Sebastian M Waszak1*, Grace Tiao2*, Bin Zhu3*, Tobias Rausch1*, Francesc Muyas4,5#, Bernardo Rodríguez-Martín6,7#, Raquel Rabionet4#, Sergei Yakneen1#, Georgia Escaramis4,8, Yilong Li9, Natalie Saini10, Steven A Roberts11, German M Demidov4,5, Esa Pitkänen1; Olivier Delaneau12-14, Jose Maria Heredia-Genestar15, Joachim Weischenfeldt1,16, Suyash S Shringarpure17, Jieming Chen18; Hidewaki Nakagawa19, Ludmil B Alexandrov20, Oliver Drechsel4,5, L Jonathan Dursi21, Ayellet V Segre2, Erik Garrison9, Serap Erkek1, Nina Habermann1, Lara Urban22, Ekta Khurana23, Andy Cafferkey22, Shuto Hayashi24, Seiya Imoto25, Lauri A Aaltonen26, Eva G Alvarez6,7, Adrian Baez-Ortega27, Matthew Bailey33, Mattia Bosio4,5, Alicia L Bruzos6,7, Ivo Buchhalter28, Carlos D. Bustamante29, Claudia Calabrese22, Anthony DiBiase30, Mark Gerstein31-33, Aliaksei Z Holik4,5, Xing Hua3, Kuan-lin Huang34, Ivica Letunic35, Leszek J Klimczak36, Roelof Koster3, Sushant Kumar31, Mike McLellan34, Jay Mashl34, Lisa Mirabello3, Steven Newhouse22, Aparna Prasad4,5, Gunnar Rätsch37, Matthias Schlesner28, Roland Schwarz38, Pramod Sharma30, Tal Shmaya17, Nikos Sidiropoulos16, Lei Song3,
    [Show full text]
  • Executive Summary Toward a Comprehensive Genomic Analysis
    National Cancer Institute and National Human Genome Research Institute National Institutes of Health U.S. Department of Health and Human Services Executive Summary Toward a Comprehensive Genomic Analysis of Cancer Convened by: Andrew von Eschenbach, M.D., Director, National Cancer Institute Francis Collins, M.D., Ph.D., Director, National Human Genome Research Institute July 20-22, 2005 The Ritz-Carlton Washington, DC Workshop Executive Summary Purpose of the Workshop “Toward a Comprehensive Genomic Analysis of Cancer” was co-organized by the National Cancer Institute (NCI) and the National Human Genome Research Institute (NHGRI) as part of their collaboration to implement the recommendation of the National Cancer Advisory Board’s Working Group on Biomedical Technology to initiate a pilot phase of the Human Cancer Genome Project (HCGP). The long-term goal of the HCGP is to develop a comprehensive catalog of the genomic changes that occur in tumors and obtain an in-depth understanding about the relation of these changes to the biological processes in cancer. Such a complete information set will potentially revolutionize the cancer research community’s strategies to develop and implement major new approaches to prevent, detect, diagnose, and treat cancer, through much more efficient clinical trials and accelerated introduction of more effective therapies. The workshop explored critical issues in cancer biology, genomic technologies, bioinformatics, and the bioethical, consent, and legal issues that must be factored into the design and implementation of a two- phase approach to an HCGP, starting with a focused pilot program. The aim of the pilot phase is to demonstrate that comprehensive characterization of a tumor type1, when analyzed in conjunction with carefully obtained, deep biological information about the tumor type, will facilitate the development of clinically meaningful applications in a way that has previously been unavailable to cancer researchers.
    [Show full text]
  • Human Genetics 1990–2009
    Portfolio Review Human Genetics 1990–2009 June 2010 Acknowledgements The Wellcome Trust would like to thank the many people who generously gave up their time to participate in this review. The project was led by Liz Allen, Michael Dunn and Claire Vaughan. Key input and support was provided by Dave Carr, Kevin Dolby, Audrey Duncanson, Katherine Littler, Suzi Morris, Annie Sanderson and Jo Scott (landscaping analysis), and Lois Reynolds and Tilli Tansey (Wellcome Trust Expert Group). We also would like to thank David Lynn for his ongoing support to the review. The views expressed in this report are those of the Wellcome Trust project team – drawing on the evidence compiled during the review. We are indebted to the independent Expert Group, who were pivotal in providing the assessments of the Wellcome Trust’s role in supporting human genetics and have informed ‘our’ speculations for the future. Finally, we would like to thank Professor Francis Collins, who provided valuable input to the development of the timelines. The Wellcome Trust is a charity registered in England and Wales, no. 210183. Contents Acknowledgements 2 Overview and key findings 4 Landmarks in human genetics 6 1. Introduction and background 8 2. Human genetics research: the global research landscape 9 2.1 Human genetics publication output: 1989–2008 10 3. Looking back: the Wellcome Trust and human genetics 14 3.1 Building research capacity and infrastructure 14 3.1.1 Wellcome Trust Sanger Institute (WTSI) 15 3.1.2 Wellcome Trust Centre for Human Genetics 15 3.1.3 Collaborations, consortia and partnerships 16 3.1.4 Research resources and data 16 3.2 Advancing knowledge and making discoveries 17 3.3 Advancing knowledge and making discoveries: within the field of human genetics 18 3.4 Advancing knowledge and making discoveries: beyond the field of human genetics – ‘ripple’ effects 19 Case studies 22 4.
    [Show full text]
  • (DMOH) Toronto General Hospital, University Health Network
    General & Consultative Academic Hematologist, Division of Medical Oncology and Hematology (DMOH) Toronto General Hospital, University Health Network The Department of Medicine, Faculty of Medicine at the University of Toronto and the Division of Medical Oncology and Hematology at the University Health Network (UHN) are seeking to recruit a general academic hematologist for the Toronto General Hospital’s Blood Disorders Program. The successful candidate will have an academic position of Clinician Investigator and must be eligible for a full-time clinical academic appointment at the rank of Lecturer or Assistant Professor at the University of Toronto. Effective start date is September 1, 2017, or shortly thereafter. The position is well suited to early career physicians with an interest in non- and pre-malignant hematology. Strong collaborative skills are required as there is an opportunity to form closer links with the malignant hematology clinics and with our principal referring internal stakeholders. The role will be primarily ambulatory clinic based, serving hematological complications from UHN’s Cardiac, Multi-Organ Transplant and Internal Medicine programs, as well as the local community. The candidate should have a strong academic interest in postgraduate MD teaching or in quality improvement/patient safety and uphold standards of excellence. Additional qualifications in these domains are preferred. The Blood Disorders Program is a core program within the Division of Medical Oncology & Hematology at the University Health Network. As one of the top health networks in the world, the University Health Network encompasses both the Princess Margaret Cancer Centre as well as the Toronto General Hospital along with each of their respective world-class research institutes: The Ontario Cancer Institute and Toronto General Research Institute.
    [Show full text]
  • Scientific Advisory Committee on Oncology Therapies (SAC-OT)
    Scientific Advisory Committee on Oncology Therapies (SAC-OT) Membership List Core Members Alexander H.G. Paterson, MD, FRCP, FACP, MBChB (Chair) Medical Oncologist, Department of Medical Oncology, Tom Baker Cancer Centre Professor, Department of Medicine and Oncology, University of Calgary Calgary, Alberta Biography: Alexander Paterson graduated Medicine from Edinburgh University, United Kingdom in 1977 and subsequently trained at St. Bartholomew’s Hospital and Royal Marsden, London, England. He is a Fellow of the Royal College of Physicians and has been a Medical Oncologist at the Tom Baker Cancer Centre in Calgary since 1990. He is also Professor in the Departments of Medicine and Oncology at the University of Calgary, Alberta since 1995. He is a member of the Alberta Out-of-Province/Country Health Services Appeal Panel and the Board of Directors of the National Surgical Adjuvant Breast and Bowel Project (NSAPB). He is also Chair of the NSABP Protocol B-34 and the Alberta Breast Cancer Programme. He has published over 100 articles, authored over 15 book chapters, is the Editor of Fundamental Problems in Breast Cancer (I and II) and contributes a regular column to Alberta Doctors’ Digest. He has given over 200 invited lectures. Rick Abbott, BScPharm, RPEBC Pharmacy Manager, Provincial Systemic Therapy, Dr. H. Bliss Murphy Cancer Centre, Eastern Health St. John’s, Newfoundland and Labrador Biography: Rick Abbott graduated from the School of Pharmacy in 1990 at the Memorial University of Newfoundland, St. John’s, Newfoundland and Labrador. He has been the Pharmacy Manager of the Provincial Systemic Therapy since 2002 and is actively involved in the Pharmacy Profession.
    [Show full text]