2021 Business Economic Outlook
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“I Have SMA, SMA Doesn't Have Me”- a Qualitative Snapshot Into The
“I have SMA, SMA doesn’t have me”- A Qualitative Snapshot into the Challenges, Successes, and Quality of Life of Adolescents and Young Adults with SMA Allison Joy Mazzella ( [email protected] ) Cure SMA https://orcid.org/0000-0002-0346-8659 Mary Curry Cure SMA Lisa Belter Cure SMA Rosangel Cruz Cure SMA Jill Jarecki Cure SMA Research Keywords: Spinal Muscular Atrophy, Quality of Life in SMA Adolescents and Young Adults, Qualitative Research, Emotional Health, Disability, Peer-Support Group, Accessibility, Fatigue, Dependence. Posted Date: October 19th, 2020 DOI: https://doi.org/10.21203/rs.3.rs-49014/v2 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Version of Record: A version of this preprint was published on February 22nd, 2021. See the published version at https://doi.org/10.1186/s13023-021-01701-y. Page 1/29 Abstract Background: With the approval of three treatments for spinal muscular atrophy (SMA) and several promising therapies on the horizon, the SMA adolescent and young adult populations are expected to evolve in the coming years. It is imperative to understand this cohort as it exists today to provide optimal care and resources, as well as to assess possible treatment effects over time. In 2018, Cure SMA launched two initiatives geared towards understanding adolescents and young adults with SMA, ages 12- 25. First, Cure SMA launched a Quality of Life (QoL) survey to capture quantitative and qualitative information on this specic age demographic. Concurrently, Cure SMA invited SMA-affected individuals, ages 12-25, to create a three-minute video on their everyday experiences living with SMA. -
Of 4 2020 Annual Report on the Administration of Colorado Parks
2020 Annual Report on the Administration of Colorado Parks and Wildlife February 2021 To: House Agriculture, Livestock, and Water Committee Senate Agriculture and Natural Resources Committee I. Statutory Requirements On June 6, 2011, Governor Hickenlooper signed Senate Bill 11-208 into law, merging the Division of Parks and Outdoor Recreation and the Division of Wildlife into the Division of Parks and Wildlife, referred to herein as Colorado Parks and Wildlife or CPW. On June 4, 2012, House Bill 12-1317 was signed into law to finalize the merger of the Divisions and to create the Parks and Wildlife Commission. Among the requirements of HB 12-1317 is the delivery to the Legislature of an annual report, more fully described below: C.R.S. 33-9-106 (2) “Beginning in 2013 AND NOTWITHSTANDING SECTION 24-1-136 (11), C.R.S., the executive director shall report annually to the joint house agriculture, livestock, and natural resources committee and the senate agriculture, natural resources, and energy committee, or any successor committees, regarding the administration of the division, including an evaluation of division resources and their utilization and an identification of opportunities for efficiencies. Each such report must summarize stakeholder outreach conducted during the prior year and must also identify disposition of assets and cost savings, both planned and realized, since the previous year, including savings pertaining to personnel, equipment, services, and provisioning.” II. Division Resource Utilization Utilization of division resources is reported to the Parks and Wildlife Commission. The FY 19-20 report on sources and uses of funds is available on the Commission’s website. -
Pine River Ranches CWPP Has Been Developed in Response to the Healthy Forests Restoration Act of 2003 (HFRA)
Pine River Ranches Community Wildfire Protection Plan July 2012 Prepared for: Pine River Ranches Land Owners Association Bayfield, Colorado and Upper Pine River Fire Protection District Bayfield, Colorado Prepared by: Short Forestry, LLC 9582 Road 35.4 Mancos, Colorado 81328 Table of Contents 1. INTRODUCTION......................................................................................................... 3 2. BACKGROUND ........................................................................................................... 3 A. Location..................................................................................................................... 3 B. Community ............................................................................................................... 3 C. Local Fire History .................................................................................................... 4 D. Recent Wildfire Preparedness Activities ............................................................... 5 3. PLAN AREA ................................................................................................................. 5 A. Boundaries ................................................................................................................ 5 B. Private Land Characteristics .................................................................................. 6 C. Public Land Characteristics.................................................................................... 7 D. Fire Protection......................................................................................................... -
Understanding and Mapping Variability of the Niobrara Formation
UNDERSTANDING AND MAPPING VARIABILITY OF THE NIOBRARA FORMATION ACROSS WATTENBERG FIELD, DENVER BASIN by Nicholas Matthies A thesis submitted to the Faculty and the Board of Trustees of the Colorado School of Mines in partial fulfillment of the requirements for the degree of Master of Science (Geology). Golden, Colorado Date________________ Signed:____________________________________ Nicholas Matthies Signed:____________________________________ Dr. Stephen A. Sonnenberg Thesis Advisor Golden, Colorado Date:_______________ Signed:____________________________________ Dr. Paul Santi Professor and Head Department of Geology and Geological Engineering ii ABSTRACT Wattenberg Field has been a prolific producer of oil and gas since the 1970s, and a resurgence of activity in recent years in the Niobrara Formation has created the need for a detailed study of this area. This study focuses on mapping regional trends in stratigraphy, structure, and well log properties using digital well logs, 3D seismic data, and core X-ray diffraction data. Across Wattenberg, the Niobrara is divided into the Smoky Hill Member (made up of A Chalk, A Marl, B Chalk, B Marl, C Chalk, C Marl, and Basal Chalk/Marl) and the Fort Hays Limestone Member. Directly beneath the Niobrara, the Codell Sandstone is the uppermost part of the Carlile Formation. Stratigraphic trends in these units are primarily due to differential compaction and compensational sedimentation. The largest structural trend is a paleo-high that runs east-west to northeast-southwest across the middle of the field. It has a relief of about 100 ft, and is 20 mi wide. The A Chalk and A Marl show evidence of submarine erosion over this area. Faults mapped from 3D seismic data are consistent with previously published data on a proposed polygonal fault system in the Denver Basin. -
GROUNDWATER LEVELS in the DENVER BASIN BEDROCK AQUIFERS 2017
GROUNDWATER LEVELS in the DENVER BASIN BEDROCK AQUIFERS 2017 by Andrew D. Flor John W. Hickenlooper Robert W. Randall Governor Executive Director, DNR Kevin G. Rein Matthew A. Sares State Engineer Manager, Hydrogeology Section GROUNDWATER LEVELS IN THE DENVER BASIN BEDROCK AQUIFERS 2017 This report updates basic data concerning the depth to and elevation of groundwater in the four main Denver Basin bedrock aquifers collected during the spring and summer of 2017. The report is organized first by aquifer, then by well name. Well completion information is provided, where available. Wells that may be completed in more than one aquifer are listed according to the uppermost aquifer. Approximately 95 water-level measurements in this year’s report were obtained by Division of Water Resources (Division) personnel. A total of six wells have been instrumented with data loggers to collect daily water-level data. These include the following: - four wells in the Castle Rock area that monitor all four Denver Basin aquifers; CO3_LTDW (DB-204), CO3_TKD (DB-205), CO6_KA (DB-206) and CO3_KLF (DB-203); and - two wells near Golden in the Pleasant View Metropolitan District are completed in the Arapahoe (DB-201) and Laramie-Fox Hills (DB-200) aquifers. Water-level data from 126 cooperator wells are also included in this report. Personnel from cooperating water districts and municipalities graciously provided these data upon request. The Division appreciates the cooperation of the many entities that provide water-level information. Recent Legislation has directed the Division of Water Resources, in consultation with the Colorado Water Conservation Board, to encourage qualified parties to submit water level data for inclusion in the statewide water level database. -
CAMPUS MAP a - Boettcher Auditorium
A B C D E F G H I LEGEND ACADEMIC BUILDINGS B 1 Ammi Hyde Building D-8 U C H 2 Boettcher West D-7 T EL CAMPUS MAP A - Boettcher Auditorium BO 1 U University of Denver 3 Chambers Center for the Advancement of Women B-3 LE VA Light Rail Station 4 Craig Hall B-5 R 54 D 5 Daniels College of Business F-5 6 English Language Center I-3 7 Fisher Early Learning Center A-4 8 Frontier Hall B-5 9 Iliff School of Theology Campus E/F-6 E. COLORADO AVE 10 Johnson-McFarlane Hall B-6 A - Theatre: Black Box Studio & White Box Studio 11 Knoebel School of Hospitality Management C-5 12 Knudson Hall F-7 13 Margery Reed Building F-5 33 14 Mass Communications E-8 15 Metallurgy E-8 2 16 Newman Center for the Performing Arts/Lamont School of Music F-7 60 A - Trevorrow Hall 53 B - Hamilton Recital Hall C - Gates Concert Hall D - Byron Theatre SOUTH WILLIAMS ST SOUTH HIGH ST BUCH TEL BO 17 Olin Hall D-7 61 ULEVA RD 18 Physics Building D-8 EAST JEWELL AVE 48 EAST JEWELL AVE EAST JEWELL AVE 19 Ricketson Law Building E-4 59 20 Ricks Center for Gifted Children F-4 21 Ritchie School for Engineering & Computer Science E-7 22 Ruffatto Hall B-4 55 58 23 Seeley Mudd Science Building D-7 24 Shwayder Art Building D-3 24A A - Nagel Art Studios 3 25 Sie International Relations Complex D-6 A - Sié Chéou-Kang Center K 6 71 26 Sturm Hall C-4 3 24 27 Wesley Hall D-7 35 OTHER BUILDINGS/FACILITIES 28 Academic Office Annex E-8 SOUTH YORK ST SOUTH YORK EAST ASBURY AVE EAST ASBURY AVE 29 Anderson Academic Commons E-5 A - Main Library 26 44 30 Aspen Hall C-6 38 31 Buchtel Bungalow I-5 -
Full Prescribing Information for Systemic Corticosteroids (Equivalent to Oral Prednisolone at 1 Mg/Kg/Day) ZOLGENSMA
HIGHLIGHTS OF PRESCRIBING INFORMATION For patients with unremarkable findings, taper the corticosteroid dose These highlights do not include all the information needed to use over the next 28 days. If liver function abnormalities persist, continue ZOLGENSMA safely and effectively. See full prescribing information for systemic corticosteroids (equivalent to oral prednisolone at 1 mg/kg/day) ZOLGENSMA. until findings become unremarkable, and then taper the corticosteroid dose over the next 28 days. Consult expert(s) if patients do not respond ® ZOLGENSMA (onasemnogene abeparvovec-xioi) suspension, for adequately to the equivalent of 1 mg/kg/day oral prednisolone. (2.1) intravenous infusion Initial U.S. Approval: 2019 ---------------------DOSAGE FORMS AND STRENGTHS---------------------- ZOLGENSMA is a suspension for intravenous infusion, supplied as WARNING: ACUTE SERIOUS LIVER INJURY single-use vials. (3) See full prescribing information for complete boxed warning. ZOLGENSMA is provided in a kit containing 2 to 9 vials, as a combination of Acute serious liver injury and elevated aminotransferases can occur 2 vial fill volumes (either 5.5 mL or 8.3 mL). All vials have a nominal with ZOLGENSMA. (5.1) concentration of 2.0 × 1013 vector genomes (vg) per mL. Each vial of Patients with pre-existing liver impairment may be at higher risk. ZOLGENSMA contains an extractable volume of not less than either 5.5 mL (8.6) or 8.3 mL. (3) Prior to infusion, assess liver function of all patients by clinical -------------------------------CONTRAINDICATIONS------------------------------ examination and laboratory testing (e.g., hepatic aminotransferases None. (4) [aspartate aminotransferase (AST) and alanine aminotransferase (ALT)], total bilirubin, and prothrombin time). Administer systemic ------------------------WARNINGS AND PRECAUTIONS----------------------- corticosteroid to all patients before and after ZOLGENSMA infusion. -
History of Arapahoe County
History of Arapahoe County Arapahoe County was named for the Arapaho Indians, one of the In the late 1820s, trappers searched larger tribes of plains Indians, who along with the Cheyenne occupied this region for beavers to supply Arapahoe County east of the foothills running into what is now western the great demand for mens beaver Kansas. Arapahoe County is Colorado’s first county, since almost hats. In the late 1830s and 1840s, half of the entire area now Colorado was Arapahoe County of the the demand shifted to buffalo Kansas territory. In 1861, when Kansas was made a state, Colorado skins. In 1832, the first trading was made a territory with Arapahoe County as one of the 17 original post on the South Platte River was counties. built on Cherry Creek, which was then part of Arapahoe County. The original Arapahoe County was 30 miles wide and extended from Sheridan Boulevard, the present western boundary of Denver, Adams In 1848, gold prospectors on and Arapahoe counties to the Kansas border. This peculiar shape was their way to California stopped in due to the practice of giving counties with large amounts of plains Colorado long enough to pan its territory at least some of the foothill territory where there was water streams. They found gold on West for mining and irrigation. Even though Arapahoe County did not Dartmouth Avenue, just west of reach the foothills, the streams running from the mountains supplied Englewood where Dry Creek flows water. As settlers came in and took up lands on the eastern portions into the Platte River. -
(719)846-1515
The Chronicle-News Trinidad, Colorado “Weekend Edition” Friday, Saturday & Sunday, May 28-30, 2021 Page 5 431 University Street, Trinidad, CO 81082 (719)846-1515 www.cotwrealestate.com TBD Vacant Land, Trinidad, 200 E Main St, Aguilar, CO 81082 | Listing Price $85,000 CO 81020 | Listing Price $199,000 214 E Kansas Ave, Trinidad, Beautiful Lot in Gated Fisher Peak Ranch Subdivision - Majestic 25110 N Ridgeline, Trinidad, Are you looking for a great place to run a successful business, look CO 81082 | Listing Price $119,000 Views of Colorado’s Newest State Park ‘’Fishers Peak’’. Views of the CO 81082 | Listing Price $795,000 no further than the Historical, Reputable and Famous Sunset Tavern Classic 1919 Bungalow in HistoricTrinidad. This Home is in a great Sangre De Cristo & Spanish Peaks Mountains along with views of the Large Acreage Hunting & Horse property located in the mountains NW in Aguilar, CO. This establishment has been in continual operation location just across from a beautiful park and walking distance to City of Trinidad. Build your Dream home, Hike on almost 55 acres. of Trinidad. This top of the mountain home sits at 7400’ in elevation for over 75 years. It has been recently renovated. The property has a downtown. New carpet, fresh paint and a Bright Spacious kitchen Close to Town, Trinidad Lake State Park and Highway of Legends offering a 360 degree vantage point, seclusion, tranquility and the quaint Bar/Restaurant on one side for your everyday operations and Scenic Byway. it adjoins the enormous Dance Hall with an additional large covered with traditional saltillo tiles and even a mudroom. -
SBDC-Annual-Report Min2.Pdf
2019 Colorado SBDC Network Overall Impact Numbers CENTER IMPACT AURORA-SOUTH CENTRAL EAST NUMBERS METRO BOULDER MOUNTAIN DENVER COLORADO Counseled Clients 560 646 34 996 599 Training Attendees 918 1,541 161 3,417 924 Jobs Created 114 243 - 334 127 Jobs Retained 65 429 - 407 53 Started Businesses 10 27 - 36 25 Increased Sales $5,184,442 $18,293,250 - $17,707,939 $9,767,825 Contracts $6,365,977 $47,280,715 - $12,858,655 $456,000 Capital Formation $6,526,101 $38,347,296 - $8,621,300 $10,171,184 CENTER IMPACT GRAND NORTHWEST NUMBERS JUNCTION LARIMER NORTH METRO COLORADO PIKES PEAK Counseled Clients 404 992 475 135 686 Training Attendees 574 1,144 370 161 2498 Jobs Created 137 173 54 31 221 Jobs Retained 105 418 79 43 279 Started Businesses 17 41 8 5 30 Increased Sales $3,793,460 $16,916,707 $8,401,301 $827,205 $13,915,276 Contracts $214,995 $1,436,927 $1,954,300 $220 $9,512,167 Capital Formation $2,121,216 $7,590,232 $5,243,687 $245,000 $15,794,694 CENTER IMPACT SAN LUIS SOUTHEAST SOUTHERN SOUTHWEST NUMBERS VALLEY COLORADO COLORADO COLORADO WEST CENTRAL Counseled Clients 45 65 163 301 219 Training Attendees 61 131 388 1,345 101 Jobs Created - - 3 85 78 Jobs Retained - - 3 47 19 Started Businesses - - - 21 7 Increased Sales - - $75,000 $2,501,300 $1,820,600 Contracts - - - $40,000 $200,000 Capital Formation - - $310,000 $4,029,800 $348,789 1 What is the Colorado SBDC? THE COLORADO SMALL BUSINESS DEVELOPMENT CENTER (SBDC) NETWORK IS DEDICATED TO HELPING EXISTING AND NEW BUSINESSES GROW AND PROSPER IN COLORADO BY PROVIDING FREE, CONFIDENTIAL CONSULTING AND NO OR The SBDC is LOW-COST TRAINING PROGRAMS AND WORKSHOPS. -
Of 23 Case No: 19-L-0846 CIRCUIT COURT for the 20TH JUDICIAL CIRCUIT COUNTY of ST. CLAIR, STATE of ILLINOIS LISA MOORE
Electronically Filed Kahalah A. Clay Circuit Clerk CARMEN GLENN 19L0846 St. Clair County CIRCUIT COURT FOR THE 20TH JUDICIAL CIRCUIT 6/22/2020 10:42 AM COUNTY OF ST. CLAIR, STATE OF ILLINOIS 9555049 LISA MOORE, individually and on behalf of ) all others similarly situated, ) ) Plaintiff, ) v. ) No. 19-L-0846 ) KIMBERLY-CLARK WORLDWIDE, INC., ) ) Defendant. ) MOTION FOR FINAL APPROVAL OF CLASS ACTION SETTLEMENT AND MEMORANDUM IN SUPPORT THEREOF Plaintiff Lisa Moore (“Plaintiff”), by and through Class Counsel,1 respectfully submits this memorandum in support of Plaintiff’s Motion for Final Approval of Class Action Settlement. The Settlement Agreement (hereafter, “Settlement”) and its exhibits are attached as Exhibit 1 to the concurrently filed Declaration of Scott A. Bursor In Support Of Plaintiff’s Application For Attorneys’ Fees, Costs, And Class Service Awards (“Bursor Decl.”). On April 21, 2020, this Court granted preliminary approval to the parties’ Settlement Agreement and ordered that the Settlement Administrator execute the approved Notice Plan. See Order Granting Preliminarily Approval of Class Action Settlement. The tremendous response from Class Members confirms that the Settlement is fair and reasonable and provides outstanding relief to the Class. Although the claims deadline is not until August 18, 2020, the Claims Administrator estimates that upon receipt of 228,311 Claims, the entire $7,000,000 Benefit Fund will be exhausted. See Exhibit MFA1, the June 22, 2020 Decl. of Jeanne C. 1 All capitalized terms not otherwise defined herein shall have the same definitions as set out in the Settlement Agreement. Page 1 of 23 Case No: 19-L-0846 Finegan (“Finegan Decl.”) ¶ 31. -
Social-Ecological Climate Resilience Southwest Colorado
SOCIAL-ECOLOGICAL CLIMATE RESILIENCE SOUTHWEST COLORADO Colorado Natural Heritage Program Salt Lake Denver SERVING San Juan SOUTHWEST Mountains COLORADO & FOUR CORNERS where the Rocky Mountains dive into the Southwestern desert Flagstaff Albuquerque SANDSTONE & RED ROCK DESERT COLORADO PLATEAU MEETS THE ROCKIES Project Goals To integrate climate science into decision-making • Build knowledge of social-ecological climate vulnerabilities to inform planning • Create scenarios and ecological models to facilitate decision-making under uncertainty • Develop and prioritize adaptive capacities and institutional arrangements • Document best practices for bringing climate science into decision-making 69% TOTAL LAND BASE = PUBLIC LANDS • Range 40-89% IMAGE OF THE OLD WEST IMAGE OF NEW WEST TOURISM- 33% AG/RANCH- 1% MINERALS/ AMENITY/SECOND OIL & GAS- 8% HOMES - 15% Ecological-Climate-Social CLIMATE SYSTEM Project Focus Knowledge ECOLOGICAL SOCIAL Livelihoods Ecosystems SYSTEMS SYSTEM Governance Species Culture Functions Values Processes Choose four The How adaptation targets Understand Current Develop three Management and Context climate and narrative scenarios Monitor and Evaluate Develop Range of Future Changes Conduct interviews , focus groups, and workshops Implement Identify Priority Actions Concerns Develop Plan for Select Priority Action Strategies Develop ecological response models Modified from Stein et al. 2014, Cross et al, and a whole lot of others Priorities Capacity Policies Resources The What Understand Current Management and Context Invasives Drought Monitor and Flooding Evaluate Develop Range of Future Changes Fire Insects & Disease Implement Identify Priority Impacts Actions Concerns Concerns Conflicts Strategies Develop Plan for Select Priority Action Strategies Resources Barriers Coordinated Actions Practice changes Enabling conditions Policy Changes No Regrets Modified from Stein et al.