Supplemental Table 2: Bovine Top 50 Upregulated with Known Function Associated with Ang II

Gene Name Abbreviation Fold Increase

Nuclear subfamily 4, group A, member 3 NR4A3 27.4 subfamily 4, group A, member 2 NR4A2 10.6 Murine FBJ osteosarcoma viral (v-fos) oncogene homolog FOS 8.1 TIS21 NR4A1 7.1 Highly similar to H. sapiens SNF1-like kinase (SNF1LK) SNF1LK 6.2 Coagulation factor III [thromboplastin, tissue factor] F3 5.1 Similar to Dual specificity phosphatase 1 (MAP kinase phosphatase-1) MKP-1 4.9 Steroidogenic acute regulatory protein STAR 4.2 Synaptonemal complex protein 3 SYCP3 4.0 Highly Similar to GDNF family receptor alpha 2 preproprotein GFRA2 4.0 Highly similar to H. sapiens HECT domain containing 1 HECTD1 3.5 Similar to Canis familiaris fosB protein FOSB 3.5 Highly similar to regulator of G-protein signalling 2 RGS2 3.3 factor jun-B JUNB 3.2 Highly similar H. sapiens dickkopf homolog 2 DKK2 3.1 Dysbindin (dystrobrevin binding protein 1) domain containing 1 DTNBP1 3.1 VEGF-receptor, flt-receptor protein VEGFR 3.0 Highly similar to H. sapiens similar to 5-nucleotidase, cytosolic II-like 1 protein 5NCIIP 2.9 Early growth response protein 1 EGR1 2.9 RTP801 RTP801 2.9 Calcipressin 1 DSCR1 2.8 Nuclear factor regulated NFIL3 gene NFIL3 2.8 AE binding protein 2, transcript variant 1 AEPB2 2.8 Not56-like protein, transcript variant 1 (LOC614624), NOT56 2.8 Mitogen-inucible gene 6 protein MIG6 2.8 8 open reading frame 4 C8ORF4 2.7 Cysteine-rich, angiogenic inducer, 61 CYR61 2.7 Serum-inducible kinase, transcript variant 1 PLK2 2.7 Cxorf5 (71-7A) protein (LOC526925) OFD1 2.7 Highly similar to H. sapiens D10 (HOXD10) HOXD10 2.7 Fibroblast growth factor 9 transcript varient 1 (glia-activating factor) FGF9 gene FGF9 2.7 v-jun avian sarcoma virus 17 oncogene homolog JUN 2.7 DNase1-Like III protein DNAS1L3 2.7 Guanylate cyclase activator 1B GUCA1B 2.6 Cyclic-AMP-dependent ATF-3 (Activating transcription factor 3) (Liver regeneration factor 1) (LRF-1) ATF-3 2.5 Transcribed locus, highly similar to X82209.2 H. sapiens mRNA for MN1 protein MN1 2.5 C13orf3 protein, transcript variant 1 C13ORF3 2.4 Nuclear factor, interleukin 3 regulated NFIL3 2.4 ATPase, Na+/K+ transporting, beta 3 polypeptide (ATP1B3) ATP1B3 2.4 Chain 67 (MHC67) gene, exon 40 MHC67 2.3 Syndecan 4 SDC4 2.3 Cysteine/histidine-rich 1 (CYHR1), transcript variant 2 CYHR1 2.3 Gamma-butyrobetaine 2-oxoglutarate dioxygenase, transcript 1 BBOX1 2.3 Wdr45 like (MGC139599) WDR45 2.3 IMP (inosine monophosphate) dehydrogenase 1 (IMPDH1) IMPDH1 2.3 Growth arrest and DNA-damage-inducible, alpha, mRNA GADD45A 2.3 receptor gamma chain variable region BVG3.1 BVG3.1 2.3 Cyclic nucleotide gated channel alpha 3 CNGA3 2.3 protein homologous to Zfp-36 in mouse, also tristetraprolin (zpf-36) ZFP36 2.3 Gamma-parvin, transcript variant 4 PARVG 2.3 CD84 antigen (leukocyte antigen) CD84 2.3