marine drugs Review Oxidative Stress and Marine Carotenoids: Application by Using Nanoformulations Yasin Genç 1, Hilal Bardakci 2, Çi˘gdemYücel 3, Gökçe ¸SekerKaratoprak 4, Esra Küpeli Akkol 5,* , Timur Hakan Barak 2 and Eduardo Sobarzo-Sánchez 6,7,* 1 Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Sıhhiye, 06100 Ankara, Turkey;
[email protected] 2 Department of Pharmacognosy, Faculty of Pharmacy, Acibadem Mehmet Ali Aydınlar University, 34752 Istanbul, Turkey;
[email protected] (H.B.);
[email protected] (T.H.B.) 3 Department of Pharmaceutical Technology, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey;
[email protected] 4 Department of Pharmacognosy, Faculty of Pharmacy, Erciyes University, 38039 Kayseri, Turkey;
[email protected] 5 Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, 06330 Ankara, Turkey 6 Instituto de Investigación e Innovación en Salud, Facultad de Ciencias de la Salud, Universidad Central de Chile, Santiago 8330507, Chile 7 Department of Organic Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, 15782 Santiago de Compostela, Spain * Correspondence:
[email protected] (E.K.A.);
[email protected] (E.S.-S.); Tel.: +90-312-2023185 (E.K.A.); +90-569-53972783 (E.S.-S.); Fax: +90-312-2235018 (E.K.A.) Received: 27 June 2020; Accepted: 11 August 2020; Published: 13 August 2020 Abstract: Carotenoids are natural fat-soluble pigments synthesized by plants, algae, fungi and microorganisms. They are responsible for the coloration of different photosynthetic organisms. Although they play a role in photosynthesis, they are also present in non-photosynthetic plant tissues, fungi, and bacteria. These metabolites have mainly been used in food, cosmetics, and the pharmaceutical industry.