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N°46 ISSN 1286-0107 2004 • No 46 • p.S1-S115 21st World Congress of the International Union of Angiology May 22-26, 2004 - Rome, Italy AIMS AND SCOPE Phlebolymphology is an international scientific journal entirely devoted to Advisory board venous disease. The aim of Phlebolymphology is to PRESIDENT provide doctors with updated and H. PARTSCH, MD interesting information on phlebology Past President of the Union Internationale de Phlébologie and lymphology written by well- Baumeistergasse 85 known specialists from different A 1160 Vienna, Austria countries worldwide. Phlebolymphology is scientifically MEMBERS supported by a prestigious editorial board. C. ALLEGRA, MD Phlebolymphology has been publish- Head, Dept of Angiology ed four times per year since 1994, President of the Union Internationale de Phlébologie and, thanks to its high scientific level, Hospital S. Giovanni Via S. Giovanni Laterano, 155 - 00184, Rome, Italy was included in the EMBASE data- base in 1998. P. COLERIDGE SMITH, MD Senior Lecturer and Consultant Surgeon, University College London Medical School Phlebolymphology is made up of The Middlesex Hospital Mortimer Street - London W1N 8AA, UK several sections: editorial, articles on phlebology and lymphology, M. COSPITE, MD news, review, and congress calendar. Head, Dept of Angiology University Clinic, Palermo, Italy G. JANTET, MD Consultant Vascular Surgeon Past President of the Union Internationale de Phlébologie 14, rue Duroc, 75007 Paris, France P. S. MORTIMER, MD Consultant Skin Physician & Senior Lecturer in Medicine (Dermatology) St George’s Hospital - Black Shaw Road, London SW17 OQT, UK A. N. NICOLAIDES, MD P. O. Box 23462, 1683 Nicosia, Cyprus M. PERRIN, MD Vascular Surgeon Past President of the Société de Chirurgie Vasculaire de Langue Française Past President of the Société Française de Phlébologie Past President of the European Venous Forum 26, Chemin de Décines - 69680 Chassieu, France L. THIERY, MD Angiologist & Surgeon Consultant, University Hospital Gent - Korte Meer 12, 900 Gent, Belgium V. WIENERT, MD CITED/ABSTRACTED Head, Dept of Phlebology IN EMBASE/Excerpta Medica University Clinic - Pauwelstrasse, 51000 Aachen, Germany © 2004 Les Laboratoires Servier - All rights reserved throughout the world and in all languages. EDITORIAL The 21st World Congress of the International Union of Angiology was held in Rome, from May 21 to 26, 2004. This Congress is always a major opportunity for an overview of current scientific progress in this field. The international parti- cipation featured over 200 world experts in the fields of vascular medicine and biology, interventional radiology, cardiology, vascular, and endovascular surgery. During daily lectures, world-renowned invited speakers, who are recognized for their significant contribution to research or clinical investigations in the field of venous diseases, reflected on their work and its repercussions. Talks by these renowned specialists alternated with plenary sessions, which covered the many facets of arterial, venous, and lymphatic diseases. In order to promote the work of a wide range of speakers and young scientists, the best abstracts on each topic were selected for free communications or poster sessions. In addition, several prizes were granted for oral presentations and articles (eg, the IASACO Prize and the IUA Prize). Unfortunately, it was only possible for the participants to attend a small number of the presentations. Therefore, the Medical Reporters Academy, a team of medical reporters organized by Servier International and chaired by Prof Nicolaides, has collected as much information as possible on the many presentations, not only for those who were present at the Congress in Rome, but also for those who were unable to attend. These articles are presented in this issue, and we hope that you will enjoy reading them. The Medical Reporter’Academy team PHLEBOLYMPHOLOGY 2004 S1 MEDICAL REPORTERS’ ACADEMY (MRA) The reports from the International Congress of Angiology were prepared by the following members of the MRA team: Grzegorz BIOLIK Elena IBORRA Patricia SENET Ul. Malwy 15 Institu Catalá de la Salut Hôpital Charles Foix 40-748 Katowice, Poland Ciutat Sanitaria i Universitaria Pavillon de l’Orbe de Bellvitge 7, avenue de la République Yves BLOMME Servicio de Angiología y 94205 Ivry-sur-Seine, France Volkskliniek Cirurgía Vascular Tichelrei Feixa Llarga s/n B-9000 Gent, Belgium 08907 L'Hospitalet de Llobregat Chaired by Vadim BOGATCHEV Barcelona, Spain 1 Gradskaya Hospital Andrew NICOLAIDES 8-6, Leninsky Prospect Daniele RIGHI P.O. Box 23462 117049 Moscow, Russia Viale Mamiani, n. 24 1683 Nicosia, 50137 Firenze, Italy Cyprus Andrzej GABRUSIEWICZ Klinika Chirurgii Naczyniowej Manuel RIMBAU MUNOZ I Angiologii CMKP Plaza Weyler N°9 2° Piso ul. Ceglowska 80 07001 Palma de Mallorca, 01-809 Warszawa, Poland Spain S2 PHLEBOLYMPHOLOGY 2004 CONTENTS Part 1 • Does peripheral vasomotion reflect coronary vasomotion? A. Pepe, M. Lombardi, I. Takacs, V. Positanoc, E. Hoffman, G. Panzarella, E. Picano PREVENTION OF VASCULAR DISEASES . .S9 Part 2 EXPANDING ROLE OF THROMBOPROPHYLAXIS: BENFITING THE MEDICAL PATIENT INVESTIGATIONS OF VASCULAR DISEASES . .S19 • Venous thromboembolism in medical patients: burden of the disease – W. Ageno SYMPOSIUM IUA/SIDV (ITALIAN SOCIETY FOR VASCULAR • State-of-the-art thrombopropylaxis in medical INVESTIGATION) patients – D. Imberti • Treatment of postcatheterization femoral false • Optimizing management of the medical patient aneurysms, usefulness of color Doppler – in the future – C. Cimminiello J. P. Laroche • Cural arterial, intraoperative, and venous duplex UPDATE ON THE PREVENTION OF VENOUS scanning – H. Van Damme, D. Ubbink THROMBOEMBOLISM • Pentasaccharides and melagatran – B. Bergqvist Oral communications • Venous thromboembolism in patients with • Real-time ultrasound evaluation in PTA stenting – cancer – A. K. Kakkar A. Amato • Extended prophylaxis – O. Dahl • Utility of D-dimer in diagnosis of deep vein • Treatment at home – H. Partsch thrombosis in hospitalized patients at high risk of venous thromboembolism – F. Verlato, A. • Duration of anticoagulant therapy – R. Hull Bertagnin, G. Camporese, M. Nardi, G. M. Andreozzi • The appropriate use of the duplex scan in ASA IN THE PREVENTION OF CARDIOVASCULAR DISEASES carotid arterty disease – T. Mehta, I. Chetter, • The rationale for using aspirin in metabolic A. Venkatasubrama, K. Mylankal, B. Ray, syndromes – G. Davi, A. Falco P. McCollum • Meta-analysis of randomized trials of aspirin • Duplex sonography in obstructive aortoiliac versus control in low-risk populations – disease: the diagnostic value of flow reversal in C. Baigent the inferior epigastric artery – M. Haumer, • Aspirin resistance – C. Patrono R. A. Bucek, M. Schillinger, A. Haumer, M. Reiter, J. Lammer, E. Minar • Determinants of the risk of upper gastrointestinal bleeding complications – • Noninvasive foot blood volume measurement in L. A. Garcia Rodriguez the assessment of limb ischemia – T. Kanetaka, T. Komiyama, A. Onozuka, T. Miyata, H. Shigematsu Oral communications • Carotid and femoral artery intimal-medial thick- Part 3 ness as an early predictor of arterial occlusive disease in patients with diabetes – A. Mozaini, M. THERAPY OF VASCULAR DISEASES . .S25 Aslam, K. Humphries, N. Stanfield A Pharmacotherapy . .S26 • Endothelium-dependent vasodilatation predicts restenosis after coronary stenting – R. Melfi, Lectures G. Patti, C. Goffredo, A. D’Ambrosio, L. Lassandro • Selective factor Xa inhibition: role in acute coro- Pepe, G. P. Carboni, M. Chello, G. Di Sciascio nary syndromes – A. G. G. Turpie PHLEBOLYMPHOLOGY 2004 S3 • Heparins, oral anticoagulants, and ASA: • State-of-the-art in elastic compression – C. Moffat survival of the fittest – J. Fareed • Compression therapy in CVD-epidemiological • Response to variations in antiplatelet drugs: data from the Bonn Vein Study – E. Rabe clinical manifestations – H. K. Breddin • Monitoring in DVT evaluation – P. Antignani • Compression therapy reduces symptoms and NEW AND OLD HEPARINS signs of acute deep vein thrombosis and post- • Serum transaminases do not increase after a thrombotic syndrome – H. Partsch 4-week administration of fondaparinux. No episodes of thrombocytopenia after 4 weeks of C Surgery . .S46 fondaparinux in major orthopedic surgery – M. R. Larsen Lectures • Innovation and challenges. The vascular sur- • Inhibition of thrombin activatable fibrinolytic geon at the crossroads – J. Fernandes e Fernandes inhibitor by heparin and defibritide – M. Florian • Minimally invasive treatment of varicose veins – • Thrombin activatable fibrinolytic inhibitor J. Bergan (TAFI) modulation by heparin: influence of endogenous variables – M. Florian • Is carotid intervention before coronary bypass grafting necessary? – N. Angelides • Generic versions of commercially available low- molecular-weight heparin (LMWHs): product individuality in therapeutic FROM ANGIOPLASTY TO STENT AND ELUTING STENTS: implications – J. Maddineni ADVANCES AND CONTROVERSIES IN INTERVENTIONAL THERAPY NEW EVIDENCE ON CARDIOVASCULAR EFFECTS OF STATINS • Carotid artery stenting with wallstents: stent inhealing and arterial remodeling – H. Ehringer • New evidences on CV event reduction with • Carotid stenting: indications and patient statins in type 2 diabetic patients – H. Colhoun selection – G. Biasi • The antiatherothrombotic effects of statins: • PTA/stent is the first option for proximal aortoi- the ATROCAP study results – M. Cortellaro liac stenosing disease – J.