Curriculum Vitae

PERSONAL INFORMATION Adamos Hadjipanayis

WORK EXPERIENCE

November 2013- Present Assistant Professor of Paediatrics European University CYPRUS (Cyprus)

May 1994- Present Assistant director Ministry of Health (Cyprus) Primary and secondary care Paediatrics

January 1994-April 1994 Paediatrician Self-employment (Cyprus) Private practice

EDUCATION AND TRAINING

May 1998-July 1998 Post Doctoral Training in Pediatric Nephrology, Fulbright Scholarship The Childrens Hospital of Philadelphia, USA (United States) Pediatric Nephrology

January 1993-September 1999 PhD University of Athens (Greece) Epilepsy in Children with Cerebral Palsy

December 1988-October 1993 Specialization: Pediatrics Ayia Sophia Childrens Hospital, University of Athens (Greece) Specialist in paediatrics

ADDITIONAL INFORMATION

Expertise 1. Expert in information technology and pediatrics.

Publications 1.Hadjipanayis A., Giannopoulos A., Fesatidou M. Spontaneous expulsion of a foreign body in a child who was hospitalized for recurrent pneumonia. Paeditriki. 1989;52: 250-256. 2.Hadjipanayis A., Tsoumakas K. The muocopolysanccharidoses (Review article). Annules Clinicae Pediatricae Universitatis Atheniensis. 1992; 39(4):241-251. 3.Hadjipanayis A., Theodoridou M., Tzannetou K., Zoumboulakis D. Iron Deficiency Anemia due to Ancylostomiasis. Paediatriki. 1993; 56:182-184. 4.Hadjipanayis A., Papathanasiou-Klontza D., Liakopoulou M., Anastasea-Vlahou K. Munchausen syndrome by Proxy. Iatriki. 1993;64(4):407-410. 5.Hadjipanayis A., Tsoumakas k., Manolaki M., Konstantopoulos A. Morquio B syndrome. Paediatriki. 1993;56:196-199. 6.Youroukos S., Hadjipanayis A., Hadjichristodoulou C., Kattamis C. Motor milestones in children with cerebral palsy. Developmental Medicine and Child Neurology. 1995;37(72):135-136. 7.Hadjipanayis A., Youroukos S., Hadjichristodoulou C., Kattamis C. Kinetic development of children with encephalic paralysis. Medical Line 1995;17:9. 8.Hadjipanayis A. Television and Child. The periscope of the Health Inspector. 1996;1:30-31.

16/12/2020 European Medicine Agency Page 1/21 9.Hadjipanayis A., Hadjichristodoulou C., Youroukos S. Epilepsy in children with cerebral palsy. Developmental medicine and child neurology 1997;39:659-663. 10.Hadjipanayis A., Hajiroussos V., Sidera M. Juveline Adamantiades-Behcets disease: a case report. Paediatriki 1999;62:223-226.

11.Hadjipanayis A., Anastasiades E. Haemolytic Uraemic syndrome in children. Paediatriki 1999; 62:325-331. 12.Hadjipanayis A., Hadjichristodoulou C., Kallias M., Sava K., Petsa A., Demetriadou K., Christodoulou C., Constantinou A., Sidera M. Prevalence of antibodies to Hepatitis A among children and adolescents in Larnaca area, Cyprus. Eur J. Epidemiol 1999; 15:903-905. 13.Hadjipanayis A., Hadjichristodoulou C., Kallias M., Sava K., Petsa A., Demetriadou K., Christodoulou C., Constantinou A., Sidera M. Prevalence of antibodies to hepatitis A among children and adolescents in Larnaca area, Cyprus. Pediatriki Bulletin 1999;1:1-5. 14.Onoufriou M., Hadjipanayis A., Petsa A., Kallias M., Sidera M. Acute hemiparesis in a ten year old child with allergic purpura. Pediatriki Bulletin 1999;1:22-24. 15.Hadjipanayis A., Sidera M. Water poisoning of infant boy, 19 months old. Iatriki 2000;78(1):66-67. 16.Onoufriou M., Hadjipanayis A., Sidera M. Autoimmune haemolytic anemia in girl infant 10 months old. Pediatriki Bulletin 2000;2:11-13. 17.Hadjipanayis A., Spyrou S., Sidera M. Acute osteomyelitis due to the Serratia marcescens virus in a two month old infant. Pediatriki Bulletin 2000;2:9-10. 18.Hadjipanayis A., Sidera M. Streptococcus pneumoniae meningitis with initial normal cerebrospinal findings in a non-immunocompromised patient. Pediatriki 2001;64(1):85-86. 19.Hadjipanayis A., Vasilliadou A. Calcinevrin inhibitors. Are they safe in the treatment of eczema?. Pediatriki Bulletin. 2005;9:55-56. 20.Hadjipanayis A., Stephanides K. Infant with hypokalemic, hypochloremic metabolic alkalosis and loss of weight. Pediatriki. 2005;68:461-466. 21.M. Theodoridou, A. Hadjipanayis, N. Persianis, S. Makri, C. Hadjichristodoulou. Pertussis outbreak detected by active surveillance in Cyprus in 2003. Eurosurveillance 2007;12(5). 22.A. J. Nicholson, S. Del Torso, A. Hadjipanayis, D. Van Esso. Childhood obesity - A public health crisis across the European Union. Pediatriki 2007;70:103-106. 23.Darina OFlanagan, H Zhao, C Joseph, N Phin, O Gryniewicz, J Kolbusz, M Rosinska, A Zielinski, P Stefanoff, C Ihekweazu, N Maxwell, S Organ, I Oliver, M Theodoridou, A Hadjipanagis, N Persianis, S Makri, C Hadjichristodoulou, JC Semenza, G Nichols, E Garcia-Pachon, I Escribano, JC Rodriguez, M Ruiz, JM Ramos, JF Navarro, G Royo, L Santos, J Simões, R Costa, S Martins, H Lecour, C Gauci, T Melillo Fenech, H Gilles, S OBrien, J Mamo, I Stabile, N Calleja, F Ruggeri, L Cuschieri, M Pires de Miranda, M Carmo Gomes, H Rebelo de Andrade, MW Kroneman, GA van Essen, Karl Ekdahl, Ines Steffens, Jeremy Duns, Kathrin Hagmaier, Renata Mikolajczyk, Mike Catchpole, Germany Johan Giesecke, Sweden Herman Goossens, Karl Kristinsson, Irena Klavs, Richard Pebody, Panayotis T Tassios, Sylvie van der Werf. Peer-reviewed European information on communicable disease surveillance and control. April-June 2007; 12(3 6). 24.M Theodoridou, A Hadjipanagis, N Persianis, S Makri, C Hadjichristodoulou. Detección de un brote de tos ferina mediante vigilancia activa en Chipre en 2003. Eurosurveillance, 2007:12 (5), 11-12 25.Adamos Hadjipanayis. Paidiatros.com. Paediatriki 2009;72:70. 26.Andromachi Katsonouri, Adamos Hadjipanayis, Eleni Demetriou, Nikos Michael, Stella Canna-Michaelidou. Human biomonitoring in Cyprus: Cotinine in children - the impact of smoking, 2004-2008. BEH Special edition / 16 june 2009:23-27. 27.S. del Torso, D. van Esso, A. Gerber, A. Drabik, A. Hadjipanayis, A. Nicholson, Z. Grossman. European Academy of Paediatrics Research in Ambulatory Setting network (EAPRASnet): a multi-national general paediatric research network for better child health. Child Care Health Dev. 2010 May;36(3):385-91. 28.Diego van Esso, Stefano del Torso, Adamos Hadjipanayis et al. Paediatric primary care in

16/12/2020 European Medicine Agency Page 2/21 Europe: variation between countries. Arch Dis Child. 2010 Oct;95(10):791-5. 2010 Apr 19. 29.A Hadjipanayis, E Peile, CJ Stefanidis. Disorders of the urinary tract European Mastercourse in Paediatrics. 2010/1, Elsevier 30.Grossman Z, van Esso D, Del Torso S, Hadjipanayis A, Drabik A, Gerber A, Miron D. Primary care pediatricians perceptions of vaccine refusal in Europe. Pediatr Infect Dis J. 2011 Mar;30(3):255-256. 31.Rousounidis A, Papaevangelou V, Hadjipanayis A, Panagakou S, Theodoridou M, Syrogiannopoulos G, Hadjichristodoulou C. Descriptive study on parents' knowledge, attitudes and practices on antibiotic use and misuse in children with upper respiratory tract infections in Cyprus. Int J Environ Res Public Health. 2011 Aug;8(8):3246-62. 2011 Aug 5. 32.Tycho J. Zuzaka, Johanna Bonkova, Domenico Caredduc, Miklos Garami , Adamos Hadjipanayis, Janez Jazbec, Joav Merrick, Joyce Miller, Candan Ozturk, Ingrid A.L. Persson, Guenka Petrova, Pablo Saz Peiro, Simon Schraub, A. Paula Simoes-Wust, Aslak Steinsbekk, Karin Stockert, Assena Stoimenova, Jan tyczynskiq, Alexandra Tzenova-Savovak, Soren Ventegodtg, Arine M. Vlieger, Alfred Langlers. Use of complementary and alternative medicine by children in Europe: Published data and expert perspectives. Complement Ther Med (2012), doi:10.1016/j.ctim.2012.01.001 33.Papaevangelou V, Rousounides A, Hadjipanagis A, Katsioulis A, Theodoridou M, Hadjichristodoulou C. Decrease of antibiotic consumption in children with upper respiratory tract infections after implementation of an intervention program in Cyprus. Antimicrob Agents Chemother. 2012 Mar;56(3):1658-61. Epub 2011 Dec 12. 34.Zachi Grossman, Stefano del Torso, Adamos Hadjipanayis, Diego van Esso, Anna Drabik, Mike Sharland. Antibiotic prescribing for upper respiratory infections: European primary paediatricians knowledge, attitudes and practice. Acta Paediatrica 2012 Sep;101(9):935-40. doi: 10.1111/j.1651-2227.2012.02754.x. 2012 Jul 7. 35.Panagakou SG, Papaevangelou V, Chadjipanayis A, Syrogiannopoulos GA, Theodoridou M, Hadjichristodoulou CS. Risk factors of antibiotic misuse for upper respiratory infections in children: Results from a cross sectional knowledge - attitude - practices study in Greece. ISRN Pediatr. 2012;2012:685302. doi: 10.5402/2012/685302. 2012 Nov 1. 36.S del Torso, D van Esso, A Hadijpanayis, Z Grossman. Research Networks in Pediatric Primary Care: Eaprasnet. Archives of Disease in Childhood, 2012: 97 (Suppl 2), A39-A39 37.Kerstin Beckera, Margarete Seiwerta, Ludwine Casteleynb, Reinhard Joasc, AnkeJoasc,Pierre Biotd, Dominique Aertsd, Argelia Castanoe, Marta Estebane, JurgenAngererf,Holger M. Kochf, Greet Schoetersg, Elly Den Hondg, Ovnair Sepaih, KarenExleyh,Lisbeth E. Knudseni, Milena Horvatj, Louis Bloemenk, Marike Kolossa-Gehringa,DEMOCOPHES consortium (Aerts D, Biot P, Katsonouri A, Hadjipanayis A, Cerna M, Krskova A, Knudsen LE, Nielsen JK, Kolossa-Gehring M, Becker K, Rudnai P, Középesy S, Mulcahy M, Burns D, Gutleb A, Fischer M, Ligocka D, Jakubowski M, Reis MF, Namorado S, Gurzau ES, Lupsa IR, Halzlova K, Jajcaj M, Horvat M, Mazej D, Castano A, Esteban M, Berglund M, Larsson K, Crettaz P, Sepai O, Lehmann A, Exley K.). A systematic approach for designing a HBM Pilot Study for Europe. Int J Hyg Environ Health. 2013 Jul 8. pii: S1438-4639(13)00098-9. doi: 10.1016/j.ijheh.2013.07.004 38.Katsonouri Andromachi. Hadjipanayis Adamos, Lavranos Giagkos. - DEMOCOPHES, . CMJ 2013;27 (4):20-24. 39.Katsonouri Andromachi. Hadjipanayis Adamos, Lavranos Giagkos. : COPHES: Consortium to perform Human biomonitoring on a European scale, 2009-2012. CMJ 2014;28 (1):28-32. 40.Neocleous V, Costi C, Kyriakou C, Kyriakides TC, Shammas C, Skordis N, Toumba M, Kyriakou S, Koliou M, Kousparou M, Onoufriou M, Hadjipanayis A, Iasonides M, Atamyan VN, Pierides A, Christophidou-Anastasiadou V, Tanteles GA, Phylactou LA. Familial mediterranean fever associated with MEFV mutations in a large cohort of cypriot patients. Ann Hum Genet. 2014 Nov 13. doi: 10.1111/ahg.12087. 41.Fiddicke U, Becker K, Schwedler G, Seiwert M, Joas R, Joas A, Biot P, Aerts D, Casteleyn L, Dumez B, Castaño A, Esteban M6, Angerer J, Koch HM, Schoeters G, Hond ED, Sepai O, Exley K,

16/12/2020 European Medicine Agency Page 3/21 Knudsen LE, Horvat M, Bloemen L, Katsonouri A, Hadjipanayis A, Cerna M, Krsková A, Jensen JF, Nielsen JK, Rudnai P, Közepésy S, Gutleb AC, Fischer ME, Ligocka D, Kamiska J, Reis MF, Namorado S, Lupsa IR, Gurzau AE, Halzlová K, Mazej D, Tratnik JS, Rivas TC, Gómez S, Berglund M, Larsson K, Lehmann A, Crettaz P, Dewolf MC, Burns D, Kellegher A, Kolossa-Gehring M. Lessons learnt on recruitment and fieldwork from a pilot European human biomonitoring survey. Environmental Research 11/2014; 42.Adamos Hadjipanayis, Zachi Grossman, Stefano del Torso, Diego van Esso, Hans Juergen Dornbusch, Artur Mazur, Anna Drabik, Giovanni Montini. Current primary care management of children aged 136 months with urinary tract infections in Europe: large scale survey of paediatric practice. Arch Dis Child 2014; Apr;100(4):341-7. 43.Stylianos Kephalopoulos, Éva Csobod, Yuri Bruinen de Bruin, Eduardo de Oliveira Fernandes, Paolo Carrer, Corinne Mandin, Marianne Stranger, Isabella Annesi-Maesano, Marcia Giacomini, Ellen Koudijs, Hans Moshammer, Peter Rudnai, Joana Madureira, Dejan Mumovic, Dainius Martuzeviius , Edvinas Krugly, Anne Hyvärinen, Martin Täubel , Kati Järvi, Zorica Zivkovic, Helena Kazmarová, Michal Jajcaj and Henrieta Savinová, Vasiliki Assimakopoulos , Margarita-Niki Assimakopoulos, John Bartzis , Krystallia Kalimeri, Eugen S. Gurzau and Iulia Neamtiu, Peter van den Hazel, Stephen Montefort, Adamos Hadjipanayis, Eduart Cani. Guidelines for healthy environments within European schools. SINPHONIE Schools Indoor Pollution and Health Observatory Network in Europe. Regional Environmental. European Union, 2014. 44.Smolders R, Den Hond E, Koppen G, Govarts E, Willems H, Casteleyn L, Kolossa-Gehring M, Fiddicke U, Castaño A,Koch HM, Angerer J, Esteban M, Sepai O, Exley K, Bloemen L, Horvat M, Knudsen LE, Joas A, Joas R, Biot P,Aerts D, Katsonouri A, Hadjipanayis A, Cerna M, Krskova A, Schwedler G, Seiwert M, Nielsen JK, Rudnaim, Berglund M, Larsson K, Grandér M, Casteleyn L, Kolossa-Gehring M, Schwedler G, Castaño A, Esteban M, Angerer J, Koch HM, Schindler BK, Schoeters G, Smolders R, Exley K, Sepai O, Blumen L, Horvat M, Knudsen LE, Mørck TA, Joas A, Joas R, Biot P, Aerts D, De Cremer K, Van Overmeire I, Katsonouri A, Hadjipanayis A, Cerna M, Krskova A, Nielsen JK, Jensen JF, Rudnai P, Kozepesy S, Griffin C, Nesbitt I, Gutleb AC, Fischer ME, Ligocka D, Jakubowski M, Reis MF, Namorado S, Lupsa IR, Gurzau AE, Halzlova K, Jajcaj M, Mazej D, Tratnik JS, Lopez A, Cañas A, Lehmann A, Crettaz P, Hond ED, Govarts E. Exposure determinants of cadmium in European mothers and their children. Environ Res. 2014 Nov 20. pii: S0013-9351(14)00382-X. doi: 10.1016/j.envres.2014.09.042. 45.Joas A, Knudsen LE, Kolossa-Gehring M, Sepai O, Casteleyn L, Schoeters G, Angerer J, Castaño A, Aerts D, Biot P,Horvat M, Bloemen L, Reis MF, Lupsa IR, Katsonouri A, Cerna M, Berglund M, Crettaz P, Rudnai P, Halzlova K, Mulcahy M, Gutleb AC, Fischer ME, Becher G, Fréry N, Jensen G, Van Vliet L, Koch HM, Hond ED,Fiddicke U, Esteban M, Exley K, Schwedler G, Seiwert M, Ligocka D, Hohenblum P, Kyrtopoulos S, Botsivali M,DeFelip E, Guillou C, Reniero F, Grazuleviciene R, Veidebaum T, Mørck TA, Nielsen JK, Jensen JF, Rivas TC,Sanchez J, Koppen G, Smolders R, Kozepesy S, Hadjipanayis A, Krskova A, Mannion R, Jakubowski M, Fucic JA, Pereira-Miguel J, Gurzau AE, Jajcaj M, Mazej D, Tratnik JS, Lehmann A, Larsson K, Dumez B, Joas R. Policy recommendations and cost implications for a more sustainable framework for European human biomonitoring surveys. Environ Res. 2014 Dec 16. pii: S0013-9351(14)00375-2. doi: 10.1016/j.envres.2014.10.012. 46.Exley K, Cano N, Aerts D, Biot P, Casteleyn L, Kolossa-Gehring M, Schwedler G, Castaño A, Angerer J, Koch HM, Esteban M, Schoeters G, Den Hond E, Horvat M10, Bloemen L, Knudsen LE, Joas R, Joas A, Dewolf MC, Van de Mieroop E, Katsonouri A, Hadjipanayis A, Cerna M, Krskova A, Becker K, Fiddicke U, Seiwert M, Mørck TA,Rudnai P, Kozepesy S, Cullen E, Kellegher A, Gutleb AC, Fischer ME, Ligocka D, Kamiska J, Namorado S,Fátima Reis M, Lupsa IR, Gurzau AE, Halzlova K, Jajcaj M, Mazej D, Tratnik JS, Huetos O, López A, Berglund M, Larsson K, Sepai O . Communication in a Human biomonitoring study: Focus group work, public engagement and lessons learnt in 17 European countries. Environ Res. 2014 Dec 11. pii: S0013-9351(14)00452-6. doi: 10.1016/j.envres.2014.12.003. 47.Fucic A, Plavec D, Casteleyn L, Aerts D, Biot P, Katsonouri A, Cerna M, Knudsen LE, Castano A, Rudnai P, Gutleb A, Ligocka D, Lupsa IR, Berglund M, Horvat M, Halzlova K, Schoeters G,

16/12/2020 European Medicine Agency Page 4/21 Koppen G, Hadjipanayis A, Krskova A, Középesy S, Arendt M, Fischer ME7, Janasik B, Gurzau AE, Gurzau ES, Grandér M, Larsson K, Jajcaj M, Kolossa-Gehring M, Sepai O, Exley K, Bartolome M, Cutanda F, Mazej D, Nielsen JK, Snoj-Tratnik J, Schwedler G, Fiddicke U, Seiwert M, Govarts E, Den Hond E, Koch HM, Lopez A, Joas A, Joas R. Gender differences in cadmium and cotinine levels in prepubertal children. Environ Res. 2014 Dec 18. pii: S0013-9351(14)00371-5. doi: 10.1016/j.envres.2014.10.008. 48.E. Efstathiou, A. Hadjipanayis, M. Alexandrou, C. Zachariadou, P. Petrou, L. Panayiotou, A. Petsa, V. Papaevangelou. Antibiotic resistance f streptococcus pneumoniae among healthy nasopharyngeal carriers 6 To 36 months f age: Data from a nation-wide surveillance study in Cyprus. Archives of Disease in Childhood 10/2014; 99(Suppl 2): A228-A228. DOI:10.1136/archdischild-2014-307384.624 49.P,Közepesy S, Evans DS, Ryan MP, Gutleb AC, Fischer ME, Ligocka D, Jakubowski M, Reis MF, Namorado S,Lupsa IR, Gurzau AE, Halzlova K, Fabianova E, Mazej D, Tratnik Snoj J, Gomez S, González S, Berglund M,Larsson K, Lehmann A, Crettaz P, Schoeters G. Interpreting biomarker data from the COPHES/DEMOCOPHES twin projects: Using external exposure data to understand biomarker differences among countries. Environ Res. 2014 Oct 14. pii: S0013-9351(14)00276-X. doi: 10.1016/j.envres.2014.08.016. 50.Castaño A, Cutanda F, Esteban M, Pärt P, Navarro C, Gómez S, Rosado M, López A, López E, Exley K, Schindler BK, Govarts E, Casteleyn L,Kolossa-Gehring M, Fiddicke U, Koch H, Angerer J, Hond ED, Schoeters G, Sepai O, Horvat M, Knudsen L, Aerts D, Joas A, Biot P, Joas R,Jiménez-Guerrero JA, Diaz G, Pirard C, Katsonouri A, Cerna M, Gutleb AC, Ligocka D, Reis FM, Berglund M, Lupsa IR, Halzlová K, Charlier C, Cullen E, Hadjipanayis A, Krsková A, Jensen JF, Nielsen JK, Schwedler G, Wilhelm M, Rudnai P, Középesy S, Davidson F, Fischer ME, Janasik B, Namorado S, Gurzau AE, Jajcaj M, Mazej D, Tratnik JS, Larsson K, Lehmann A, Crettaz P, Lavranos G, Posada M. Fish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries. Environ Res. 2015 Feb 6. pii: S0013-9351(14)00393-4. doi: 10.1016/j.envres.2014.10.029. 51.A Hadjipanayis. IS-064 Do Apps Make Paediatricans Life Easier and How? Archives of Disease in Childhood, 2014: 99 (Suppl 2), A20-A20 52.Casteleyn L, Dumez B, Becker K, Kolossa-Gehring M, Den Hond E, Schoeters G, Castaño A, Koch HM, Angerer J, Esteban M, Exley K, Sepai O,Bloemen L, Horvat M, Knudsen LE, Joas A, Joas R, Biot P, Koppen G, Dewolf MC, Katsonouri A, Hadjipanayis A, Cerná M, Krsková A,Schwedler G, Fiddicke U, Nielsen JK, Jensen JF, Rudnai P, Közepésy S, Mulcahy M, Mannion R, Gutleb AC, Fischer ME, Ligocka D,Jakubowski M, Reis MF, Namorado S, Lupsa IR, Gurzau AE, Halzlova K, Jajcaj M, Mazej D, Tratnik Snoj J, Posada M, López E, Berglund M,Larsson K, Lehmann A, Crettaz P, Aerts D. A pilot study on the feasibility of European harmonized Human Biomonitoring: Strategies towards a common approach, challenges and opportunities. Environ Res. 2015 Mar 4. pii: S0013-9351(14)00392-2. doi: 10.1016/j.envres.2014.10.028. 53.Den Hond E, Govarts E, Willems H, Smolders R, Casteleyn L, Kolossa-Gehring M, Schwedler G, Seiwert M, Fiddicke U, Castaño A, Esteban M, Angerer J, Koch HM, Schindler BK, Sepai O, Exley K, Bloemen L, Horvat M, Knudsen LE, Joas A, Joas R, Biot P, Aerts D, Koppen G, Katsonouri A, Hadjipanayis A, Krskova A,Maly M, Mørck TA, Rudnai P, Kozepesy S, Mulcahy M, Mannion R, Gutleb AC, Fischer ME, Ligocka D, Jakubowski M, Reis MF, Namorado S, Gurzau AE, Lupsa IR, Halzlova K, Jajcaj M, Mazej D, Tratnik JS, López A, Lopez E, Berglund M, Larsson K, Lehmann A, Crettaz P, Schoeters G. First steps toward harmonized human biomonitoring in Europe: Demonstration project to perform human biomonitoring on a european scale. Environ Health Perspect. 2015 Mar;123(3):255-63. doi: 10.1289/ehp.1408616. 54.Katsonouri A., Fischer M.E., Hadjipanayis A., Arendt M., Lavranos G., Hoffmann L., Maurer- Chronakis K., Guignard C., Fragopoulou C., Cocco E., Anastasi E., Pilavakis D., Efstathiou E., Demetriou L., Hadjiefthychiou A., Demetriou E., Aerts D., Casteleyn L., Biot P., Kolossa-Gehrin M., Den Hond E., Schoeters G., Castaño A., Esteban M., Fiddicke U., Exley K., Sepai O., Gutleb A.C. Harmonized european human biomonitoringin small countries: challenges, opportunities and lessons learned in Cyprus and Luxembourg from the DEMOCOPHES study. Biomonitoring 2015; 2: 21-34.

16/12/2020 European Medicine Agency Page 5/21 55.Hadjipanayis A, Efstathiou E, Neubauer D. Benign paroxysmal torticollis of infancy: an underdiagnosed condition. J Paediatr Child Health. 2015 Jul;51(7):674-8. doi: 10.1111/jpc.12841. 56.Tom Stiris, Stefano del Torso, Jean-Christophe Mercier, Shimon Barak, Bjorn Wettergrem, Robert Ross-Russell, Arunas Valiulis, Adamos Hadjipanayis. Improving paediatric care in the community. The Lancet 2015;385 (9977):1505. 57.Pietro Ferraraemail, Maria Amato, Adamos Hadjipanayis, Stefano del Torso, Tom Stiris. The rights of children arriving in Europe. The Lancet 2015 Nov 14; 386 (10007):1939-1940. 58.Hans Jürgen Dornbusch, Tom Stiris, Stefano del Torso, Robert Ross-Russell, Jernej Zavrsnik, Björn Wettergren, Jean-Christophe Mercier, Arunas Valiulis and Adamos Hadjipanayis. Human papillomavirus vaccination crisis in Japan. Journal of Paediatrics and Child Health 2015;51: 1146-1147. 59.Jacek Karas, Shai Ashkenazi, Alfredo Guarino, Andrea Lo Vecchio, Raanan Shamir, Yvan Vandenplas, Hania Szajewska, Penelope A Bryant, Suzanne L Boyce, Emma King, Antonio Clavenna, R Perchard, D MacDonald, J Say, J Pitts, S Pye, J Allgrove, K Banerjee, R Amin, Adamos Hadjipanayis, Zachi Grossman, Stefano del Torso, Diego van Esso, Hans Juergen Dornbusch, Artur Mazur, Anna Drabik, Giovanni Montini, Céline Marsaud, Sylvie Rossignol, Patrick Tounian, Irène Netchine, Béatrice Dubern, Indi Trehan, Mark J Manary, Gemma Buckley, Katherine Belessiotis, Ina Schim van der Loeff, Krishna Jada, Virginia A Hill, Miwako Nagasaka, Ichiro Morioka, Tomoyuki Yokota, Kaori Fujita, Daisuke Kurokawa, Tsubasa Koda, Akio Shibata, Hideto Yamada, Yoshiya Ito, Eiko Uchino, Chika Shirai, Kazumoto Iijima, Michael Parker, Maria Bitner-Glindzicz. Child health. Archives of Disease in Childhood 2015:100 (4), 359-363 60.Adamos Hadjipanayis, Alexios Klonis, Omar Assem Abdel-Mannan, Alastair G Sutcliffe. Smartphone use in paediatric practice: a national survey. Journal MTM 5:1:3-8, 2016. doi:10.7309/jmtm.5.1.2. 61.Julia A. Bielicki, Charlotte I.S. Barker, Alike W. van der Velden, Mike Sharland1, Diego van Esso, Adamos Hadjipanayis, Stefano del Torso and Zachi Grossman, Antibiotic preferences for childhood pneumonia vary by physician type and European region. ERJ Open Research. ERJ Open Res 2016; 2: 00001-2016 - DOI: 10.1183/23120541.00001-2016. 62.Neocleous V, Byrou S, Toumba M, Costi C, Shammas C, Kyriakou C, Christophidou-Anastasiadou V, Tanteles GA, Hadjipanayis A and Phylactou LA. Evidence of digenic inheritance in auto-inflammation-associated genes. J Genet. 2016 Dec;95(4):761-766. doi:10.1007/s12041-016-0691-5. 63.Zachi Grossman, Stefano del Torso, Diego van Esso, Jochen Ehrich, Peter Altorjai, Artur Mazur, Corinne Wyder, Ana Margarida Neves, Hans Jurgen Dornbusch, Elke Jaeger Roman, Antonella Santucci, Adamos Hadjipanayis Primary care paediatricians' use of electronic health records in Europe. Child Care Health Dev. 2016 Nov;42(6):928-933. doi: 10.1111/cch.12374. 64.Hadjipanayis A, Efstathiou E, Alexandrou M, Panayiotou L, Zachariadou C, Petrou P, Papaevangelou V. Nasopharyngeal Pneumococcal carriage among healthy children in Cyprus post widespread simultaneous implementation of PCV10 and PCV13 Vaccines. PLoS One. 2016 Oct 5;11(10):e0163269. DOI: 10.1371/journal.pone.0163269. 65.Elisavet Efstathiou, Sophia Papamichalopoulou, George Georgiou and Adamos Hadjipanayis. Rapid onset of purpuric rash in an otherwise healthy 6-month-old infant. Clin Pediatr (Phila). 2016 Oct 23 DOI: 10.1177/0009922816674524. 66.Adamos Hadjipanayis, Tom Stiris, Stefano del Torso, Jean-Christophe Mercier, Arunas Valiulis, Jonas Ludvigsson. Europe needs to protect children and youths against secondhand smoke. Eur J Pediatr. 2016 Nov 14. DOI: 10.1007/s00431-016-2805-8. 67.Adamos Hadjipanayis. Fever phobia for parents and physicians. Eur J Pediatr (2016) 175: 1393. doi:10.1007/s00431-016-2785-8. 68.Jonas Ludvigsson, Tom Stiris, Stefano del Torso, Jean-Christophe Mercier, Arunas Valiulis, Adamos Hadjipanayis. European Academy of Paediatrics statement: Vision zero for child deaths in traffic accidents. Eur J Pediatr. 2017 Feb;176(2):291-292 DOI: 10.1007/s00431-016-2836-1. 69.A Hadjipanayis. Interdisciplinary Session 22: Temperature management: Different conditions,

16/12/2020 European Medicine Agency Page 6/21 different approach. European journal of pediatrics, 2016, 175 (11), 1425-1425 70.Dornbusch HJ, Hadjipanayis A, Del Torso S, Mercier JC, Wyder C, Schrier L, Ross-Russell R, Stiris T, Ludvigsson JF. We strongly support childhood immunisation-statement from the European Academy of Paediatrics (EAP). Eur J Pediatr. 2017 Mar 10. doi: 10.1007/s00431-017-2885-0. 71.Grossman Z, Hadjipanayis A, Stiris T, Del Torso S, Mercier JC, Valiulis A, Shamir R. Vitamin D in European children-statement from the European Academy of Paediatrics (EAP). Eur J Pediatr. 2017 Apr 12. doi: 10.1007/s00431-017-2903-2. 72. JF Ludvigsson, A Hadjipanayis, S Torso, JC Mercier, A Valiulis, T Stiris. Appropriate use of antibiotics is vital for public health. Acta Paediatr. 2017 May;106(5):691. doi: 10.1111/apa.13772. 73.Mazur A, Dembinski L, Schrier L, Hadjipanayis A, Michaud PA. European Academy of Paediatric consensus statement on successful transition from paediatric to adult care for adolescents with chronic conditions. Acta Paediatr. 2017 May 4. doi: 10.1111/apa.13901. 74.Hadjipanayis A. Are we too afraid of fever? Archives of Disease in Childhood 2017; 102 (Suppl 2), A6-A6 75.Hadjipanayis A, T Stiris, S del Torso, JC Mercier. Europos pediatr akademijos pareikimas: Europa turi apsaugoti vaikus ir jaunuolius nuo pasyvaus rkymo. VAIKØ PULMONOLOGIJA, 3. 2017 76.Taminskiene V, Vaitkaitiene E, Valiulis A, Turner S, Hadjipanayis A, Stukas R, Valiulis A. The self-reported quality of life of Lithuanian children with asthma was comparable to Western populations. Acta Paediatr. 2017 Nov 6. doi: 10.1111/apa.14140. 77.Adamos Hadjipanayis, Elisavet Efstathiou, Leda Theophilou, George Chrousos. Reversible brain lesion following growth hormone replacement therapy in an adolescent. BMJ Case Reports 2017; doi:10.1136/bcr-2017-221885 78.Artur Mazur, Margherita Caroli, Igor Radziewicz-Winnicki, Paulina Nowicka, Daniel Weghuber, David Neubauer, ukasz Dembinski, Francis P. Crawley, Martin White1, Adamos Hadjipanayis. Reviewing and addressing the link between mass media and the increase in obesity among European children: The European Academy of Paediatrics (EAP) and The European Childhood Obesity Group (ECOG) consensus statement. Acta Paediatrica 2017 October 20, DOI:10.1111/apa.14136 79.SZILVIA KÖZÉPESY, KATALIN KOVÁCS, MIKLÓS NÁRAY, ESZTER TÓTH, TERÉZIA CSAJA, ERZSÉBET FRANKÓ, ARANKA KOVÁCS, MIHÁLY JÁNOS VARR, ELLY DEN HOND, EVA GOVARTS5 , HANNY WILLEMS, ROEL SMOLDERS, LUDWINE CASTELEYN, MARIKE KOLOSSA-GEHRING, GERDA SCHWEDLER, ARGELIA CASTAÑO , MARTA ESTEBAN , JÜRGEN ANGERER , HOLGER M. KOCH , BIRGIT K. SCHINDLER , OVNAIR SEPAI, KAREN EXLEY, LOUIS BLOEMEN, MILENA HORVAT, LISBETH E. KNUDSEN, ANKE JOAS, REINHARD JOAS1, PIERRE BIOT, DOMINIQUE AERTS, GUDRUN KOPPEN, MARGARETE SEIWER, ULRIKE FIDDICKE , ANDROMACHI KATSONOURI, ADAMOS HADJIPANAYIS, ANDREA KRSKOVA, MAREK MALY, MILENA CERNA, THIT A. MØRCK, MAURICE MULCAHY, RORY MANNION, ARNO C. GUTLEB, MARC FISCHER, DANUTA LIGOCKA, MAREK JAKUBOWSKI, M. FÁTIMA REIS, SÓNIA NAMORADO, ANCA E. GURZAU, IOANA-RODICA LUPSA, KATARINA HALZLOVA, MICHAL JAJCAJ, DARJA MAZEJ, JANJA SNOJ TRATNIK, ANA LOPE8 , ESTRELLA LOPEZ , MARIKA BERGLUND. Democophes Hu A Human Biomonitoring Study for the Assessment of Environmental Exposures of School-Aged Children and their Mothers in Hungary. Central European Journal of Occupational and Environmental Medicine, 2017; 23 (3-4); · 191-216 80.A. CarrascoSanz, I. LeivaGea, L. MartinAlvarez, S. del Torso, D. van Esso, A. Hadjipanayis, A. Kadir, J. RuizCanela, O. PerezGonzalez, Z. Grossman. Migrant children's health problems, care needs, and inequalities: European primary care paediatricians' perspective. Child Care Health Dev. 2017;15. DOI: 10.1111/cch.12538 81.Pierre-André Michaud, Lenneke Schrier, Robert Ross-Russel, Laila van der Heijden, Lien Dossche, Sian Copley, Tommaso Alterio, Artur Mazur, Lukasz Dembinski, Adamos Hadjipanayis, Stefano del Torso, Helena Fonseca, Anne-Emmanuelle Ambresin. Paediatric departments need to improve residents training in adolescent medicine and health: A position paper of the European Academy of Paediatrics. Eur J Pediatr. 2017 Dec 21. doi: 10.1007/s00431-017-3061-2 82.Lenneke Schrier, Adamos Hadjipanayis, Stefano del Torso, Tom Stiris, Marieke Emonts, Hans

16/12/2020 European Medicine Agency Page 7/21 Juergen Dornbusch. European Antibiotic Awareness Day 2017: training the next generation of health care professionals in antibiotic stewardship. European Journal of Pediatrics, 2017. DOI: 10.1007/s00431-017-3055-0 83.Adamos Hadjipanayis, Zachi Grossman, Stefano del Torso, Kyriaki Michailidou, Diego Van Esso, Rita Cauwels. Oral health training, knowledge, attitudes and practices of primary care paediatricians: a European survey. European journal of pediatrics https://doi.org/10.1007/s00431-018-3108-z. 84.Michaud PA, Schrier L, Ross-Russel R, van der Heijden L, Dossche L, Copley S, Alterio T7, Mazur A, Dembinski L, Hadjipanayis A, Del Torso S, Fonseca H, Ambresin AE. Paediatric departments need to improve residents' training in adolescent medicine and health: a position paper of the European Academy of Paediatrics. Eur J Pediatr. 2018 Apr;177(4):479-487. doi: 10.1007/s00431-017-3061-2. Epub 2017 Dec 21. 85.Ewald DA, Huss G, Auras S, Caceres JR, Hadjipanayis A, Geraedts M. Development of a core set of quality indicators for paediatric primary care practices in Europe, COSI-PPC-EU. Eur J Pediatr. 2018 Apr 14. doi: 10.1007/s00431-018-3140-z. 86.Jernej Zavrnik, Tom Stiris, Lenneke Schrier, Robert Ross Russell, Stefano del Torso, Arunas Valiulis, Jean-Christophe Mercier, Károly Illy, Adamos Hadjipanayis. Basic training requirements for health care professionals who care for children Eur J Pediatr. 2018 Apr 14. DOI : 10.1007/s00431-018-3150-x 87.Adamos Hadjipanayis, Francis P. Crawley, Tom Stiris, David Neubauer, Pierre-André Michaud. Child trafficking in Europe: what is the paediatricians role? A statement by the European Academy of Paediatrics. European Journal of Pediatrics. Doi: 10.1007/s00431-018-3190-2 88.Z Grossman, A Hadjipanayis, A Degani, E Somekh. Tracking Changes in Vaccine Attitudes and Decisions: Results from 2008 and 2016 Parental Surveys. Pediatr Infect Dis J. 2018 Jul 11. doi: 10.1097/INF.0000000000002147 89.Adamos Hadjipanayis, Elisavet Efstathioua, Kyriaki Michaelidou, Vasiliki Papaevangelou. Adherence to pneumococcal conjugate vaccination schedule and uptake rate as compared to the established diphtheria-tetanus-acellular pertussis vaccination in Cyprus. Vaccine. https://doi.org/10.1016/j.vaccine.2018.08.021 90.Adamos Hadjipanayis. Compliance with vaccination schedules. Human Vaccines & Immunotherapeutics. Accepted author version posted online: 14 Dec 2018, Published online: 16 Jan 2019. https://doi.org/10.1080/21645515.2018.1556078 91.Vaida Taminskiene, Tomas Alasevicius, Algirdas Valiulis, Egle Vaitkaitiene, Rimantas Stukas, Adamos Hadjipanayis, Steve Turner, Arunas Valiulis. Quality of life of the family of children with asthma is not related to asthma severity. Eur J Pediatr. 2019 Jan 4. doi: 10.1007/s00431-018-3306-8. 92.A. Valiulis, J. Bousquet, A. Veryga8, U. Suprun, D. Sergeenko, S. Cebotari, D. Borelli, S. Pietikainen, J. Banys, I. Agache, N. E. Billo, A. Bush, I. Chkhaidze, L. Dubey, W. J. Fokkens, J. Grigg, T. Haahtela, K. Julge, O. Katilov, N. Khaltaev, M. Odemyr, S. Palkonen, R. Savli, A. Utkus, V. Vilc, T. Alasevicius, A. Bedbrook, M. Bewick, J. ChorostowskaWynimko, E. Danila, A. Hadjipanayis, R. Karseladze, V. Kvedariene, E. Lesinskas, L. Münter, B. Samolinski, S. Sargsyan, B. Sitkauskiene, D. Somekh, L. Vaideliene, A. Valiulis and P. W. Hellings. Vilnius Declaration on chronic respiratory diseases: multisectoral care pathways embedding guided selfmanagement, mHealth and air pollution in chronic respiratory diseases. Clin Transl Allergy. 2019 Jan 28;9:7. doi: 10.1186/s13601-019-0242-2. eCollection 2019. 93.P Fanis, E Efstathiou, V Neocleous, LA Phylactou, A Hadjipanayis. A novel heterozygous duplication of the SLC12A3 gene in two Gitelman syndrome pedigrees: indicating a founder effect. Journal of Genetics (2019) 98 (1), 5. 94.Adamos Hadjipanayis, Elisavet Efstathiou, Antonia Hadjieftychiou, Lia Demetriou, Giagkos Lavranos, Andromachi Katsonouri. Challenges in implementing of school-based recruitment for human biomonitoring research. JOURNAL OF ENVIRONMENTAL AND OCCUPATIONAL SCIENCE (2019) 8 (1), 1-7

16/12/2020 European Medicine Agency Page 8/21 95.Dere K, Weghuber D, Caroli M, Koletzko B, Thivel D, Frelut M, Socha P, Grossman Z, Hadjipanayis A, Wyszyska J, Mazur A. Consumption of Sugar-Sweetened Beverages in Paediatric Age: A Position Paper of the European Academy of Paediatrics and the European Childhood Obesity Group. Ann Nutr Metab 2019;74:296302 https://doi.org/10.1159/000499828 96. A Hadjipanayis, E Efstathiou, V Papaevangelou. Hepatotoxicity in an Adolescent with Black Iced Tea Overconsumption Pediatr Gastroenterol Hepatol Nutr. 2019 Jul;22(4):387-391. doi: 10.5223/pghn.2019.22.4.387. Epub 2019 Jun 19. 97.Hadjipanayis A, Efstathiou E, Altorjai P, Stiris T, Valiulis A, Koletzko B, Fonseca H. Social media and children. What is the paediatricians role? Eur J Pediatr. 2019 Oct;178(10):1605-1612. doi: 10.1007/s00431-019-03458-w. Epub 2019 Aug 30. 98.Ketil Størdal, Corinne Wyder, Andreas Trobisch, Zachi Grossman, Adamos Hadjipanayis. Overtesting and overtreatment - statement from the European Academy of Paediatrics (EAP). Eur J Pediatr. 2019 Oct;178(10):1605-1612. doi: 10.1007/s00431-019-03458-w. Epub 2019 Aug 30. 99.Berthold Koletzko, Karin Bergmann, J Thomas Brenna, Philip Calder, Cristina Campoy, M Tom Clandinin, John Colombo, Mandy Daly, Tamás Descsi, Hans Demmelmair, Magnus Domellöf, Nataa Fidler Mi, Ines Gonzalez-Casanova, Johannes B van Goudoever, Adamos Hadjipanayis, Olle Hernell, Alexandre Lapillonne, Silke Mader, Camilia R Martin, Valerie Matthäus, Usha Ramakrishan, Cornelius M Smuts, Sean JJ Strain, Conny Tanjung, Patrick Tounian, Susan E Carlson. Choices for adding long-chain polyunsaturated fatty acids to infant formula. A position paper of the European Academy of Pediatrics and the Child Health Foundation. American Journal of Clinical Nutrition. 2019/9/6. https://eprints.soton.ac.uk/id/eprint/434154 100.Adamos Hadjipanayis, Hans Jürgen Dornbusch, Zachi Grossman, Leda Theophilou, Joe Brierley. Mandatory vaccination: a joint statement of the Ethics and Vaccination working groups of the European Academy of Paediatrics. European Journal of Pediatrics 2019. DOI: 10.1007/s00431-019-03523-4 101.Hadjipanayis A, van Esso D, Del Torso S, Dornbusch HJ, Michailidou K, Minicuci N, Pancheva R, Mujkic A, Geitmann K, Syridou G, Altorjai P, Pasinato A, Valiulis A, Soler P, Cirstea O, Illy K, Mollema L, Mazur A, Neves A, Zavrsnik J20, Lapii F, Efstathiou E, Kamphuis M, Grossman Z. Vaccine confidence among parents: Large scale study in eighteen European countries. Vaccine. 2019 Dec 14. pii: S0264-410X(19)31622-6. doi: 10.1016/j.vaccine.2019.11.068. 102.Schrier L, Hadjipanayis A, Stiris T, Ross-Russell RI, Valiulis A, Turner MA, Zhao W, De Cock P, de Wildt SN, Allegaert K, van den Anker J. Off-label use of medicines in neonates, infants, children, and adolescents: a joint policy statement by the European Academy of Paediatrics and the European society for Developmental Perinatal and Pediatric Pharmacology. Eur J Pediatr. 2020 Jan 3. doi: 10.1007/s00431-019-03556-9. 103.Pierre-André Michaud, Richard Bélanger, Artur Mazur, Adamos Hadjipanayis & Anne-Emmanuelle Ambresin How can primary care practitioners address substance use by adolescents? A position paper of the EUROPEAN academy of PAEDIATRICS. European Journal of Pediatrics. https://doi.org/10.1007/s00431-020-03596-6 104.Hans Jürgen Dornbusch, Timo Vesikari, Alfredo Guarino, Andrea LoVecchio, Adamos Hadjipanayis, Berthold Koletzko. Rotavirus vaccination for all children or subgroups only? Comment of the European Academy of Paediatrics (EAP) and the European Society for Paediatric Infectious Diseases (ESPID) recommendation group for rotavirus vaccination. European Journal of Pediatrics. https://doi.org/10.1007/s00431-020-03608-5 105.Barbara Rath, Lea Seeber, Wolfgang Maurer, Armin Haghi, Stefano del Torso, Hans Juergen Dornbusch, Adamos Hadjipanayis, Andreas Trobisch. Strengthening Education and knowledge on immunization. A joint initiative for the EU Coalition for Vaccination. February 29, 2020 106.Jonathan D Klein, Berthold Koletzko, Mortada H El-Shabrawi, Adamos Hadjipanayis, Naveen Thacker, Zulfiqar Bhutta. Promoting and supporting childrens health and healthcare during COVID-19International Paediatric Association Position Statement. Arch Dis Child. 2020 May 7. pii: archdischild-2020-319370. doi: 10.1136/archdischild-2020-319370 107.Juan Emmanuel Dewez, Ruud G Nijman, Stefano del Torso, Zachi Grossman, Adamos

16/12/2020 European Medicine Agency Page 9/21 Hadjipanayis, Diego Van Esso, David Bath, Marieke Emonts, Emma Lim, Alec Miners, Lucy Pembrey, Shunmay YeungThe availability and use of diagnostic tests for the management of acute childhood infections in Europe: the protocol for a cross-sectional survey of paediatricians. London School of Hygiene & Tropical Medicine. 2020/3/2 108.Hadjipanayis A, Efstathiou E Editorial Commentary on the paper Mandatory Vaccination in Europe. Transl Pediatr 2020;9(3):206-209. doi: 10.21037/tp-20-128 109.Lopes H, Middleton J, De Guchtenaere A, Hadjipanayis A. ASPHER statement on the use of masks by children. ASPHER (2020). DOI: 10.13140/RG.2.2.17790.61762 110.Jochen Ehrich, Massimo Pettoello Mantovani, Eleanor Molloy, Reinhold Kerbl, Mehmet Vural, Simon Lenton, Stefano del Torso, Adamos Hadjipanayis, Björn Wettergren, Zachi Grossman. The challenges of adapting hospital care for children. The Changing Role of the Hospital in European Health Systems. 2020 https://www.euro.who.int/__data/assets/pdf_file/0010/448048/Changing-role-of-hospitals-eng.pdf 111.Pierre-André Michaud, Richard Bélanger, Artur Mazur, Adamos Hadjipanayis, Anne-Emmanuelle Ambresin. How can primary care practitioners address substance use by adolescents? A position paper of the EUROPEAN academy of PAEDIATRICS. Eur J Pediatr. 2020 Aug;179(8):1297-1305. doi: 10.1007/s00431-020-03596-6. Epub 2020 Feb 20. 112.Ramen Munir Baloch, Cara Nichole Maesano, Jens Christoffersen, Soutrik Banerjee, Marta Gabriel, Éva Csobod, Eduardo de Oliveira Fernandes, Isabella Annesi-Maesano, Péter Szuppinger, Réka Prokai, Petur Farkas, Cecilia Fuzi, Eduart Cani, Jasna Draganic, Eszter Réka Mogyorosy, Zorica Korac, Gabriela Ventura, Joana Madureira, Inês Paciência, Anabela Martins, Ricardo Pereira, Elisabete Ramos, Peter Rudnai, Anna Páldy, Gyula Dura, Tímea Beregszászi, Éva Vaskövi, Donát Magyar, Tamás Pándics, Zsuzsanna Remény-Nagy, Renáta Szentmihályi, Orsolya Udvardy, Mihály J Varró, Stylianos Kephalopoulos, Dimitrios Kotzias, Josefa Barrero-Moreno, Rahmije Mehmeti, Aida Vilic, Daniel Maestro, Hanns Moshammer, Gabriela Strasser, Piegler Brigitte, Philipp Hohenblum, Eddy Goelen, Marianne Stranger, Maarten Spruy, Momchil Sidjimov, Adamos Hadjipanayis, Andromachi Katsonouri-Sazeides, Eleni Demetriou, Ruzana Kubinova, Helena Kazmarová, Beatricia Dlouha, Bohumil Kotlík, Helen Vabar, Juri Ruut, Meelis Metus, Kristiina Rand, Antonina Järviste, Aino Nevalainen, Anne Hyvarinen, Martin Täubel, Kati Järvi, Corinne Mandin, Bruno Berthineau, Heinz-Joern Moriske, Marcia Giacomini, Anett Neumann, John Bartzis, Krystallia Kalimeri, Dikaia Saraga, Mattheos Santamouris, Margarita Niki Assimakopoulos, Vasiliki Asimakopoulos, Paolo Carrer, Andrea Cattaneo, Salvatore Pulvirenti, Franco Vercelli, Fabio Strangi, Elida Omeri, Silvia Piazza, Andrea D'Alcamo, Anna Clara Fanetti, Piersante Sestini, Magdalini Kouri, Giovanni Viegi, Sandra Baldacci, Sara Maio, Vincenzo Franzitta, Salvatore Bucchieri, Fabio Cibella, Margherita Neri, Dainius Martuzeviius, Edvinas Krugly, Stephen Montefort, Peter Fsadni, Piotr Z Brewczyski, Ewa Krakowiak, Jolanta Kurek, Elbieta Kubarek, Agnieszka Wlazo, Carlos Borrego, Célia Alves, Joana Valente, Eugen Gurzau, Cristina Rosu, Gabriela Popita, Iulia Neamtiu, Cristina Neagu, Dan Norback, Phylomena Bluyssen, Michel Bohms, Peter Van Den Hazel, Flemming Cassee, Yuri Bruinen de Bruin, Alena Bartonova, Aileen Yang, Katarína Halzlová, Michal Jajcaj, Milada Kániková, Olga Miklankova, Marianna Vítkivá, Milena Jovsevic-Stojanovic, Marija Zivkovic, Zarko Stevanovic, Ivan Lazovic, Zana Stevanovic, Zorica Zivkovic, Sofija Cerovic, Jasmina Jocic-Stojanovic, Dejan Mumovic, Paula Tarttelin, Lia Chatzidiakou, Evangelia Chatzidiakou, Marie-Christine Dewolf. Indoor air pollution, physical and comfort parameters related to schoolchildren's health: Data from the European SINPHONIE study. Sci Total Environ. 2020 Jun 6;739:139870. doi: 10.1016/j.scitotenv.2020.139870. 113.Juan Emmanuel Dewez, Ruud G Nijman, Stefano del Torso, Zachi Grossman, Adamos Hadjipanayis, Diego Van Esso, David Bath, Marieke Emonts, Emma Lim, Alec Miners, Lucy Pembrey, Shunmay Yeung. The availability and use of diagnostic tests for the management of acute childhood infections in Europe: the protocol for a cross-sectional survey of paediatricians. London School of Hygiene & Tropical Medicine, London, United Kingdom. 2020. DOI: https://doi.org/10.17037/PUBS.04656309

Projects 1.MOCHA Models of Child Health Appraised. Horizon 2020 project

16/12/2020 European Medicine Agency Page 10/21 Co-leader of WP H: The Role of Electronic Records and Data to Support Effective Models. A forty months project starting June 2015. 2.Paediatricians practices and perspectives concerning Urinary Tract Infections (UTIs) in children 1 to 36 months of age This research was carried out by European Academy of paediatrics Research in ambulatory Settings (EAPRASnet). January to March 2013 Project leader 3.Pneumococcal carriage in Cyprus in children aged 6-36 months Coordinator and scientific advisor. The project is funded by GSK and takes place in cooperation with the following institutions: 2nd Department of Paediatrics, Athens University, Childrens General Hospital of Athens Panayiotis & Aglaia Kyriakou Athens Department of Paediatrics Larnaca Hospital Microbiology Laboratory Larnaca Hospital This project began on May, 2012 and will be completed on November, 2014. 4.Demonstration Of A Study To Coordinate And Perform Human Biomonitoring On A European Scale DEMOCOPHES The DEMOCOPHES pilot study will look at biomarkers for mercury, cadmium, phthalates as well as environmental tobacco smoke in human hair and urine. The project will collect samples and data from 120 mother-child pairs in each participating country. The project is funded by Life. The project started in September 2010 and is expected to be completed in November 2012. Coordinators for Cyprus: Dr Adamos Hadjipanayis Dr Andromachi Katsonouri For more information you can visit the website of the project http://www.eu-hbm.info/democophes 5.Schools Indoor Pollution and Health: Observatory Network in Europe SINPHONIE Thirty-six environment and health institutions from 25 countries are participating in the SINPHONIE research project in order to implement Regional Priority Goal III (RPG3) of the Childrens Environment and Health Action Plan for Europe (CEHAPE), which is to prevent and reduce respiratory disease due to outdoor and indoor air pollution. The project is funded by DG Sanco. The project started in October 2010 and is expected to be completed in September 2012. Scientific coordinator for Cyprus: Adamos Hadjipanayis For more information you can visit the website of the project http://www.sinphonie.eu/ 6.Consortium to Perform Human Biomonitoring on a European Scale COPHES. The main objective of COPHES is the development of a functional framework allowing the collection of comparable HBM data throughout Europe. The project is funded by FP7. The project started in December 2009. Adamos Hadjipanayis: co manager for Cyprus. For more information you can visit the website of the project http://www.eu-hbm.info/cophes 7.Homes and cars smoke free. Coordinator and scientific advisor. The project is funded by the Research Promotion Foundation of Cyprus and takes place in cooperation with the following institutions: Cyprus Pediatric Society State General Lab University of Athens National parents association

16/12/2020 European Medicine Agency Page 11/21 This project began on April 12, 2009 and completed on July 11, 2011. 8.EAPRASnet (European Academy of Paediatrics Research in Ambulatory Settings network). Member of the steering committee. Started in January 2009 9.Use and abuse of antibiotics in upper respiratory tract infections. Coordinator and scientific advisor. The project is funded by the Research Promotion Foundation of Cyprus and takes place in cooperation with the following institutions: Cyprus Pediatric Society University of Thessaly Ministry of Health, Cyprus This project began on November 8, 2005 and is expected to be completed on November 8, 2008. 10.Task-Force in Europe for Drug Development for the Young. This project is funded by the 6th Framework of European Union (FP6-Contract LSHB-CT-2005-005216). Initiated in 2005 and is expected to be completed in 2008. Twelve European countries participate. Participate as a representative of Cyprus and of the European Academy of Pediatrics. 11.Use of mobile phones by children. Research project funded by the National Committee Environment and Childs Health. Implemented in 2006. Coordinator and scientific advisor of the project. 12.Registration of rare infectious diseases Chief researcher in the specific project, which has been funded by the Research Promotion Foundation of Cyprus and was implemented in 2005. The following institutions also participated: Cyprus Pediatric Society Hellenic Pediatric Society University of Athens University of Thessaly Cyprus Ministry of Health 13.Passive smoking. Research project which has been funded by the National Committee for the Environment and Childs Health. Implemented between November 2004-March 2005. Coordinator and scientific advisor of the project. 14.Serological and molecular epidemiology of Mediterranean spotted fever in Cyprus. Research project implemented in 1994-1995 by the University of Crete. Participated as researcher from Cyprus. 15.Epilepsy in children with Cerebral palsy. Research project subsidized by the Greek Ministry of Health. Coordinator and scientific advisor. Implemented in 1993-1996.

Memberships Memberships 1.President of the European Academy of Pediatrics 2. Member of Cyprus Pediatric association 3. Memebr of the steering committee of EAPRASnet HONORS/DISTINCTIONS/AWARDS Greek Neurology Company prize for best publication in International Medical Journal in Epilepsy: May 1998 Fulbright Scholarship for professional training in Pediatric Neurology. U.S.A. October 1997 Award for best work at the Annual Panhellenic Medical Conference for the work: Tracing and standardization of Ricketsias in Cyprus using the PCR-RFLP technique. 1998 Funding from the Greek Ministry of Health to undertake a study for the subject: Epilepsy in Children with Cerebral Palsy September 1993 PARTICIPATION IN WORKSHOPS

I.ARPEC, Antimicrobial Resistance and Prescribing in European Children, 2 Day Conference - Royal College of Paediatrics and Child Health, London. 15th and 16th October 2009

16/12/2020 European Medicine Agency Page 12/21 II.Fifth Ministerial Conference on Environment and Health Parma, Italy, 1012 March 2010. Preparatory meeting 14-15 November 2009. III.Declaration of the Fifth Ministerial Conference on Environment and Health. 13-14 November 2009 IV.Capacity building to cope with health impacts of climate change. Limassol 1st September 2009. V.Moderator. The value of HPV vaccine in prophylaxis of cervical cancer and the other HPV-associated diseases. 27-29 March, Warsaw, Poland. VI.Moderator. Cervical cancer and Beyond: Implementing effective Primary Prevention Programs. Dubai 19-20 March 2009. VII.Europet. (www.europet.org). EUROPET is a European Pediatrics Thematic Network (Socrates programme) coordinated by the University of Oulu. The main objectives of the European Pediatrics Thematic Network (EUROPET) address educational, professional and regional issues in European pediatric education, aiming to achieve uniformly high standards of pediatric services across Europe. EUROPET supports European initiatives, arising from the Bologna Process using Tuning principles and represents an international collaboration between a number of European agencies and associations. Istanbul 11-12 April 2008. VIII.Attention Deficit Disorder With or Without Hyperactivity. 15-16 March 2008. Nicosia, Cyprus. IX.Moderator. Strategies for Vaccination at the international conference A new era in cervical cancer and genital warts prevention, Limassol, Cyprus. X.The Future of Our Children. Implementing the Commitments of the Fourth Ministerial Conference on Environment and Health Vienna, Austria, 13-15 June 2007. Representative of the Cyprus Ministry of Health. XI.10 May 2007, Cyprus. Workshop of Adolescent Medicine. Organized by Eurotech. XII.8 December 2006, Nicosia, Cyprus. Building the Capacities for Effective Diagnosis and Prevention of the Impacts of the Environment on Childrens Health. Organized by the National Committee on Environment and Children Health in cooperation with WHO/EURO. XIII.25 November 2005. Nicosia, Cyprus. Workshop on DEVELOPING a CEHAP for Cyprus. Implementing the Commitments of the Fourth Ministerial Conference on Environment and Health 2004, The Future of our Children. XIV.Organized by the National Committee on Environment and Children Health in Cooperation with WHO/EURO. XV.8-10 June 2005 Rome, Italy. Capacity building for health care providers on childrens health and environment building up a Train the trainers network. WHO XVI.5 December 2004. Nicosia, Cyprus. Building the Capacities for Effective Diagnosis and Prevention of the Impacts of the Environment on Childrens Health. Seminar for Pediatricians. Organized by the National Committee on Environment and Children Health in Cooperation with WHO/EURO. CONFERENCE ANNOUNCEMENTS / PRESENTATIONS

1.Karen Exley1, Greet Schoeters1 *, Den Hond Elly 1, Govarts Eva 1, Koppen Gudrun 1, Willems Hanny 1, Smolders Roel1 , Joas Reinhard 2, Casteleyn Ludwine3, Joas Anke2, Biot Pierre4, Aerts Dominique4, Angerer Juergen5, Berglund Marika6, Bloemen Louis7, Castano Argelia8, Cerna Milena9, Crettaz Pierre10, Esteban Marta8, , Fabianova Eleonora12, Fiddicke Ulrike13, Fischer Marc14, Gutleb Arno Christian15, Hadjipanayis Adamos16, Halzlova Katarina12, Horvat Milena17, Jakubowski Marek18, Katsonouri Andromachi19, Knudsen Lisbeth20, Koch Holger5, Kolossa-Gehring Marike13, Krskova Andrea9, Lehmann Andrea10, Ligocka Danuta18, Lupsa Ioana-Rodica21, Mazej Darja17, Mulcahy Maurice22, Namorado Sónia23, Nielsen Jeanette20, Reis M. Fátima23, Rudnai Peter24, Schwedler Gerda13, , Tratnik Snoj Janja 1 Sepai Ovnair1. Human Biomonitoring A Harmonised European Approach: EU and UK Results. Public Health England Annual Conference 10-11 September 2013 2.Smolders Roel1*, Den Hond Elly 1, Govarts Eva 1, Koppen Gudrun 1, Willems Hanny 1, Joas Reinhard 2, Casteleyn Ludwine3, Joas Anke2, Biot Pierre4, Aerts Dominique4, Angerer Juergen5, , Berglund Marika6, Bloemen Louis7, Castano Argelia8, Cerna Milena9, Crettaz Pierre10, Esteban

16/12/2020 European Medicine Agency Page 13/21 Marta8, Exley Karen11, Fabianova Eleonora12, Fiddicke Ulrike13, Fischer Marc14, Gutleb Arno Christian15, Hadjipanayis Adamos16, Halzlova Katarina12, Horvat Milena17, Jakubowski Marek18, Katsonouri Andromachi19, Knudsen Lisbeth20, Koch Holger5, Kolossa-Gehring Marike13, Krskova Andrea9, Lehmann Andrea10, Ligocka Danuta18, Lupsa Ioana-Rodica21, Mazej Darja17, Mulcahy Maurice22, Namorado Sónia23, Nielsen Jeanette20, Reis M. Fátima23, Rudnai Peter24, Schwedler Gerda13, Sepai Ovnair11, Tratnik Snoj Janja 17, Greet Schoeters1. Interpreting biomarker data from the COPHES-DEMOCOPHES twin projects: Using lifestyle and environmental data to understand biomarker differences among countries. Ninth International Symposium on Biological Monitoring 2013. 9-11 September 2013, Manchester, UK 3.Stella Canna Michaelidou, Andromachi Katsonouri, Eleni Demetriou, Mr. Nikos Michael and Adamos Hadjipanayis. ANTISMOKING CAMPAIGN AND EVALUATION OF CHILDREN EXPOSURE TO PASSIVE SMOKING IN CYPRUS. INCHES 6th INTERNATIONAL CONFERENCE ON CHILDREN'S HEALTH AND THE ENVIRONMENT,14-16 November 2011, LOTZ Poland 4.A. Katsonouri, E. Demetriou, N. Michael, D. Evangelidou and A. Hadjipanayis. ASSESSMENT OF THE EXPOSURE OF CYPRIOT CHILDREN TO ENVIRONMENTAL TOBACCO SMOKE. MESAEP - Mediterranean Scientific Association of Environmental Protection. September 24-27, 2011, Ioannina - Greece 5.Adamos Hadjipanayis. The first universal hearing screening program in the Mediterranean: CYPRUS. 29th UMEMPS CONGRESS UNION OF MIDDLE EASTERN AND MEDITERRANEAN PEDIATRIC SOCIETIES. 14-17 September 2005. 6.Adamos Hadjipanayis. Changing Epidemiology of Pertussis in Cyprus. International Network of Pediatric Surveillance Units. Lisbon 2004. 7.Adamos Hadjipanayis. Seroprevalence Study of Hepatitis A in Children and Teenagers in the Larnaca district. Panhellenic Pediatric Conference. Kos 2000. 8.Adamos Hadjipanayis. Seroprevalence l Study of Hepatitis A in Children and Teenagers in Larnaca district. 17th Pancyprian Medical Conference. Nicosia 1999 9.Adamos Hadjipanayis. Fever of Unknown Causes. 2nd Scientific Plenary of Larnaca Hospital 1999. 10.Adamos Hadjipanayis. Prenatal Hydronephrosis. 2nd Scientific Plenary of Larnaca Hospital 1999 11.Adamos Hadjipanayis. Juvenile type of Adamantiade-Behcet Syndrome. 16th Pancyprian Medical Conference. Nicosia 1998 12.Adamos Hadjipanayis. Recurrent Hemolytic Uraemic Syndrome. Panhellenic Medical Conference. Greece 1997 13.Adamos Hadjipanayis. Serological and Molecular Epidemiology of Mediterranean Spotted Fever in Cyprus. 4th Scientific Meeting of European Society of Chemotherapy. 1996 14.Adamos Hadjipanayis. Detection and typing of rickettsial strains in ticks from Cyprus with the technique PCR-RFLP. 22nd Panhellenic Medical Conference. Greece 1996 15.Adamos Hadjipanayis. Motor Milestones in Children with Cerebral Palsy. The 1st Congress of the European Pediatric Neurology Society in conjunction with the 1st Interim Meeting of the European Society for Pediatric Neurosurgery. Israel 1995 16.Adamos Hadjipanayis. Cerebral Palsy. Clinical Forms, Accompanying problems, Prognostic Indicators. Panhellenic Neurological Conference. Greece 1995 17.Adamos Hadjipanayis. Cerebral Palsy in Greece. Panhellenic Pediatric Conference 1994 18.Adamos Hadjipanayis. Heterogenic imaging findings in children with spastic hemiplegia. Panhellenic Paediatric Neurology Conference, Greece 1993 19.Adamos Hadjipanayis. Comparative Study between the pharyngeal coating culture and strept-test for the diagnosis of streptococcus tonsillitis. Panhellenic Pediatric Conference. Greece 1992 20.Adamos Hadjipanayis. Aspiration of Foreign body. Five-year Experience. Panhellenic Medical Conference. Greece 1990 21.Adamos Hadjipanayis. Vaccination State in Kavalas Area. Conference of Mediterranean and Middle East countries, Greece 1990

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SPEECHES / LECTURES A. Invited Speaker at International Conferences

1.Opening the 32nd Congress of the Polish Pediatric Society, Krakov, 19-22 June 2013 2.Anaphylaxis. Primary paediatrician perspectives. «Curso de Formação Avançada em Alergologia Pediátrica». (Module 7: Allergic Diseases and Community). 20th April 2012. Lisbon 3.Pros and Cons of websites and online data collection in pediatric research in ambulatory settings. 5th Europaediatrics Congress. 23-26 June, 2011, Vienna 4.General Pediatric consultants in Europe. First International Congress on Pediatric Primary Care. 11-13 May 2011. Tel Aviv, Israel. 5.Breast-feeding vs. formula: What is right and when for which baby? 6th Cyprus Dietetic and Nutrition Association Conference with International Participation. Theme: Life Cycle Nutrition. 23 26 September 2010. Hilton Cyprus, Nicosia Cyprus 6.Closing remarks at the international conference A New Era in Cervical Cancer and Genital Warts Prevention, Limassol, Cyprus. 7.Plenary speaker at the WORLD PEDIATRIC CONFERENCE 2007. Round table discussion on the subject Primary Care Pediatrics. Spoke on The future role of the Pediatrician in Europe. 8.Plenary Speaker at the PanEuropean Pediatric Conference. Information Technology. 14th Congress of the European Society for Ambulatory Pediatrics. Milan 2003 9.Pediatric Approach to Urological Problems. Invited speaker at the roundtable discussion of the 5th Scientific Meeting of Pediatricians to Eastern Macedonia and Thace, Samos 2000.

B. Presentation to Medical Doctors at Local and National Conferences 1.Community acquired pneumonia. 2nd National Congress on Paediatric Infectious diseases. Limassol 27-28 June 2013 2.Cases of poisoning by environmental factors. Environmental impact on the child: From uncertainties to prevention and treatment. Institute of Neurology and Genetics, Nicosia, 11 October 2012 3.Pertussis. 1st National Congress on Paediatric Infectious diseases. Nicosia 9-10 June 2012 4.When to suspect child's exposure to environmental hazards. Impact of the environment on the child: Prevention the only option, Nicosia, 18 November 2011 5.Mobile Phones: Latest Developments. Impact of environment on the child: Prevention the only option, Nicosia, 18 November 2011. 6.Vaccine against human papillomavirus. Training course "Inter-ethnic relationships and health." Paphos, 1-13 November 2011 7.The effects of tobacco on childrens health. Data and Reality. Workshop on the occasion of World Tobacco Day. Journalists House, Nicosia. May 31 2011 8.Back pain in Children and Teenagers. Workshop, Larnaca general Hospital. Nicosia 18 October 2008 9.Back pain in Children and Teenagers. Pedo-orthopedic Conference. Nicosia 10 April 2008 10.Recent Developments on the HPV Vaccine. Pancyprian Conference of the Medical Association of Paphos Asklipios, Paphos 1-2 December 2007 11.Seminar Environment and Health. Interreg III. 26-28 November 2007. Participation with three different lectures. i. Passive Smoking and Asthma ii. Electromagnetic Radiation and Effects on Health iii. Mercury Poisoning 12.Pertussis vaccine. 10th Pancyprian Pediatric Congress. Challenges from Childhood to Adolescence. 10-11 November 2007 13.The implementation of the rights of children. 13th Pancyprian Conference on the Protection and Wellbeing of Children. 17-18 November 2007, Ayia Napa 14.HPV Vaccine and prevention methods. Three different speeches at pediatricians in Paphos,

16/12/2020 European Medicine Agency Page 15/21 Limassol and Larnaca. 2007 15.Information Technology in Medicine. Medical Association Galinou. 2007 16.Structuring the Possibilities of Effective Protection and Diagnosis of the Effects of the Environment in Children. Nicosia 2006 i. Mercury ii. Electromagnetic radiation 17.Electromagnetic radiation and child. 21st Pancyprian Pediatric Conference. Nicosia 19-20 November 2005 18.Pertussis. 4th Post-graduate Pediatric Seminar. Nicosia 2003 19.Itching and itching illnesses. 6th Scientific Plenary of Larnaca Hospital. Larnaca 22 June 12 2003 20.Respiratory Alkalosis. Galinou. Larnaca 29 May 2003 21.Fever. 5th Biplenary of Larnaca Hospital. 21-22 June 2002 22.Prenatal Hydronephrosis. Vesicoureteral reflux. Cyprus Pediatric Company. 28 February 2002 23.Acute Abdominal Pain. Famagusta Medical Association Galinos. 6 February 2002 24.Pan sinusitis in a five year old boy with extended fever. Famagusta Medical Association Galinos. December 2000 25.Meningitis with normal CSF. Bi-monthly presentations of interesting cases. Pediatric Clinic. Larnaca Hospital. February 2000 26.Water Poisoning. Bi-monthly presentations of interesting events. Pediatric Clinic. Larnaca Hospital. September 1999 27.Limping. Bi-monthly Presentations of Interesting Cases. Pediatric Clinic. Larnaca Hospital, January 1999 28.Hepatitis A, B,C,D, E, F. Contemporary Literary Data for Prevention. Invited speaker from the Medical Association Galinos 1998 29.Fever of Unknown Origin. Invited by the Association of Fellows and Members of the Royal Colleges of U.K. 19787 30.Asthma. Clinical Investigation. Invited Speaker From the Institutes of Biomedical Science 1997 C. Presentations to other groups

1.Presentation of seven different presentations in a workshop on "Advances in Clinical Pediatrics". Organized by the Ministry of Health and Cyprus Nurses Society, 23 and 24 May 2012 2."Environmental factors that affect the health and development of the fetus and child." National Committee "Environment and Health of the child. "Cleopatra Hotel. Nicosia, May 11, 2010. 3.Impact of environmental hazards on human health. Postgraduate courses Pedagogical Institute of Cyprus. May 10, 2010. Limassol 4.Vaccine against human papillomavirus. Seminar for teenagers. Interracial relationships and reproductive health. Limassol March 20-21 2010 5.Man's reproductive system. Seminar for teenagers. Interracial relationships and reproductive health. Limassol March 20-21 2010 6.Passive smoking and children. National conference of teachers working at kindergarten. Limassol, 6 November 2009 7.Mobile phone and children. National conference of teachers working at kindergarten. Limassol, 6 November 2009 8.Electromagnetic radiation and childs health. National Conference for Cypriot Mayors. Nicosia 23 March 2009. 9.My Child is Hyperactive. What Should I Expect From my Pediatrician? 1st Pancyprian Conference (ADHD). 15 March 2008. 10.Passive smoking and its effect to health. Presentation to the the teachers working in Nicosia district. 17 October 2008 11.Vaccinations and Their Usefulness. Ayia Napa, 23 November 2007 12.Use and Abuse of Antibiotics. Open Lectures to Parents. 2007 13.Prevention from HPV. Speeches Organized by the Cyprus Pediatric Company for the General

16/12/2020 European Medicine Agency Page 16/21 Public. Presented 11 Such Lectures. 14.Emergency Cases in Pediatric. Invited Speaker of the Ministry of Education. The Seminar Addressed the School Assistants/Escorts. 22 February 2007 15.Psycho development of Infant and Child. Ministry of Health, Nursing Visitors branch. 24 March 2006, Nicosia 16.Conditions of Safety in the Environment of the Child. 12th Pancyprian Conference of the Pancyprian Coordinating Committee of the Protection and Wellbeing of the Child. Kakopetria. 12-13 November 2005 17.Bird Flu. Larnaca 2005 18.Information Technology in Medicine. 10th Pancyprian Conference of Nursing. Nicosia 2003.

D. President/Coordinator at Round-Table Discussions

1.Lessons learned from the implementation of a harmonized European HPM pilot study. Human Biomonitoring: Linking Environment to Health and Supporting Policy, Larnaca 22-25 October 2012 2.Criteria to include a new vaccine in the routine immunization schedule of children. 11th Pancyprian Pediatric Conference. Nicosia 29-30 November 2008 3.Screening Issues. 2nd Congress of the EAP. Nice, October 24-28, 2008. 4.Social Paediatrics. 2nd Congress of the EAP. Nice, October 24-28, 2008. 5.Epidemiology. 2nd Congress of the EAP. Nice, October 24-28, 2008. 6.Evaluation and treatment of pain in pediatric practice. 3rd Europediatrics 2008. June 14-17, Turkey 7.5th Panhellenic Conference of Sub-specialties in Pediatrics. 8-9 March 2008. Athens 8.7th Medical Conference of Galinos. Larnaca 15-16 March 2008 9.Leading the Way for the Prevention of Cervical Cancer and Beyond. 29 Feb-2 March. Prague 2008 10.Strategies for Vaccination. A New Era in Cervical Cancer and Genital Warts Prevention. 20-21 October, Limassol, Cyprus CONFERENCE PARTICIPATION

1.2nd Pediatric conference on infectious diseases. 27-28 April 2013. Limassol 2.Conference of Makarios Hospital. Nicosia. 13-14 April 2013 3.14th Postgraduate workshop. The allergic child in clinical practice. Hotel "Great Britain", Athens, February 2, 2013. 4.European Academy of Pediatrics. 11-12 May 2012, Prague 5.1st Pediatric conference on infectious diseases. Hilton Nicosia, 9-10 June 2012. 6.5th Intensive conference on Adolescent Medicine, Athens, 16-17 March 2012 7.COPHES Omics and metals workshop. Copenhagen, 12-14 March 2012 8.1st International Conference on Nutrition and Growth, held in Paris March 1-3, 2012 9.Emotional concerns on the existence and the road to freedom. "An interview with Dr Irvin Yalom". February 25, 2012. Nicosia 10.The pediatric clinical practice. Mediterranean Hotel. Limassol January 18, 2012. 11.Impact of environment on the child: Prevention the only option, Nicosia, 18 November 2011 12.27th IPV Conference and clinical workshop, Berlin, Germany, September 17-22 2011 13.5th Europaediatrics Congress. 23-26 June, 2011, Vienna 14.1st Baltic Paediatric Congress together with spring conference of European Academy of Paediatrics and the annual conference of European Confederation of Primary Care Paediatricians. 19-22 May, 2011 15.The Toddler age: Nutrition and health challenges. Prague 19 March 2011. 16.3rd Congress of the EUROPEAN ACADEMY OF PAEDIATRIC SOCIETIES, October 23-26, 2010, Copenhagen, Denmark 17.6th Cyprus Dietetic and Nutrition Association Conference with International Participation. Theme: Life Cycle Nutrition. 23 26 September 2010. Hilton Cyprus, Nicosia Cyprus

16/12/2020 European Medicine Agency Page 17/21 18.European Academy of Pediatrics. 14-18 April 2010,Luxembourg 19.Hypercholesterolaemia in children and adolescents. Up to European guidelines for diagnosis and treatment. 16 April 2010, Luxembourg 20.Baby skin care: An evolving science. Frankfurt. March 17-18 2010. 21.Lessons Learned from conjugated vaccines. European Academy of Pediatrics. Brussels. 4 December 2009. 22.12th Pancyprian Pediatric Conference. Nicosia 28-29 November 2009 23.European Academy of Pediatrics. 24-26 April 2009,Porto, Portugal 24.Cervical cancer and Beyond: Implementing effective Primary Preventive Programs. Abu Dhabi. March 19-20, 2009. 25.11th Pancyprian Pediatric Conference. Nicosia 29-30 November 2008 26.2nd Congress of the EAP. Nice, October 24-28, 2008. 27.11 Scientific Plenary at Larnaca Hospital. Larnaca 18-19 October 2008 28.15th Paediatric Rheumatology European Society Congress, 14-17 September, London, UK 29.Pediatric meeting. Pediatric Clinic of Larnaca Hospital. Sandy Beach 21st of June 2008. 30.3rd Europediatrics 2008. June 14-17, Turkey 31.26th Annual Meeting of the European Society for Paediatric Infectious Diseases. Graz, Austria 13-17 May, 2008 32.European Academy of Pediatrics. 25-26 April 2008, Grado, Italy 33.Pedo-orthopedic conference. Nicosia 10 April 2008 34.5th Panhellenic Conference of Sub-specialties. 8-9 March 2008. Athens 35.Leading the way for the prevention of cervical cancer and beyond. 29 Feb-2 March. Prague 2008 36.7 December. HPV: Primary prevention of cancer and the challenge for the pediatrician. Brussels 2007 37.7-8 December. CESP meeting 2007. Brussels 2007 38.20-21 October. A new era in cervical cancer and genital warts prevention. Limassol-Cyprus 39.10th Pancyprian Pediatric Congress. Challenges from Childhood to Adolescence. 10-11 November 2007 40.10-12 May. CESP meeting 2007. Cyprus 2007 41.Developing the Possibilities of Effective Prevention and Diagnosis of the Effects of the Environment on the Health of the Child. Nicosia 8 Decemer 2006 42.9th Pancyprian Pediatric Conference. Nicosia 25-26 November 2006 43.8th International Symposium of Pediatrics. Paphos 27-28 October 2006 44.6 May 2006. 3rd Plenary of Pediatric Clinics of the Makarios Hospital in Nicosia. Conference room ARCHANGELOS. Nicosia 45.11-12 February 2006. 11th International Symposium of Prenatal Medicine. Limassol, Cyprus 46.Teddy Network of Excellence in a wider web of relations. Paris. 13-14 February 2006 47.9 December. Conference on vaccines. Brussels 2005

48.9-11 December. CESP meeting 2005. Brussels 2005 49. 8th Pancyprian Pediatric Conference. Nicosia. 19-20 November 2005 50.Postgraduate Seminar on Pediatrics. B Pediatric Clinic of the University of Athens. 5-6 November 2005. Athens 51.29th UMEMPS CONGRESS UNION OF MIDDLE EASTERN AND MEDITERRANEAN PEDIATRIC SOCIETIES. 14-17 September 2005. Istanbul 52.Capacity building for health care providers on childrens health and environment Building up a Train the trainers network, Rome, Italy 8-10 June 2005 53.7th Postgraduate Seminar of Pediatrics. Nicosia 2005 54.Hypertension. Larnaca 28 May 2005 55.28 April-1 May. CESP meeting 2005. Slovenia 56.Purpose and use of the Microbiological lab in Everyday Clinical practice. Hospital lab, Larnaca General Hospital. 24 March 2005

16/12/2020 European Medicine Agency Page 18/21 57.2nd Pancyprian Conference of Sub-specialties in Pediatrics. Limassol 26-27 February 2005 58.19 February 2005. The allergic child in clinical practice. B Pediatric Clinic of the University of Athens. Athens 2005 59.10 December. Conference on medicine/drugs to children. Brussels 2004 60.10 December. Conference on the flu vaccine. Brussels 2004 61.10-11 December. CESP meeting 2004. Brussels 62.Plenary on the environment and the child. World Health Organization. Cleopatra Hotel. Nicosia 5 December 2004 63.6th Postgraduate Seminar on Pediatrics. Nicosia 2004 64.7th Scientific Plenary at Larnaca Hospital. Larnaca 22 June 2004 65.5th Postgraduate Seminar on Pediatrics. Nicosia 2004

66.4th International Pedo-orthopedic Seminar. Nicosia. April 2004 67.1st Plenary on Pediatrics. Nicosia Makarios Hospital. 27 March 2004 68.13-14 March 2004. 3rd Panhellenic Conference on Pediatric Sub-specialties. Athens 2004 69.28-29 February 2004. 10th International Symposium on Prenatal Medicine. Limassol, Cyprus 70.6 December. CESP meeting 2003. Brussels 71.5 December. Conference on the chickenbox vaccine. Brussels 2003 72.4th Postgraduate Seminar on Pediatrics. Nicosia 2003 73.10th Pancyprian Nursing Conference. Nicosia 2003 74.7th International Symposium on Pediatrics. Limassol 2003 75.14th Congress of the European Society for Ambulatory Pediatrics, Milan 2003 76.6th Scientific Plenary at Larnaca Hospital. Larnaca 22 June 2003 77.3rd Postgraduate Seminar on Pediatrics. A Pediatric Clinic of the University of Athens. Nicosia 10-11 May 2003 78.1st Conference on Pediatric Sub-specialties. Limassol 1-2 February 2003 79.CESP meeting 2002. Brussels, 7 December 2002. 80.Conference on Pneumonococcus. Brussels, 6 December, 2002. 81.22nd Postgraduate Seminar on Pediatrics of the B Pediatric Clinic of the University of Athens, 23-24 November 2002. 82.5th Bi-plenary Session at Larnaca Hospital. Larnaca, June 2002 83.5th Medical Conference Galinou. Larnaca, Cyprus, 30-31 March 2002. 84.International Conference on Prenatal Medicine. Limassol, 2-3 March 2002. 85.3rd Pedo-orthopedic Conference. Nicosia, Cyprus, 7 March 2002. 86.Symposium of Pediatric Respiratory Illnesses. Nicosia, 12-13 January 2002. 87.1st Postgraduate Seminar on Pediatrics of the B Pediatric Clinic of the University of Athens. Nicosia, 17-18 November 2001. 88.CESP Annual meeting. Oslo, Norway, 24-27 May 2001. 89.Dyslexia. Pediatric Company of Cyprus. Speaker: Professor Pavlides. 17 March 2001 90.6th International Symposium on Pediatrics, Nicosia 2000 91.5th Scientific Meeting of the Pediatrics of Eastern Macedonia and Thrace, Samos 2000 92.International Conference on Prenatal Medicine, 2000 93.17th Pancyprian Medical Conference, 1999 94.2nd Scientific Plenary Session at Larnaca Hospital, 1999 95.14th Medical Conference Ippokratis 1999 96.4th Medical Conference Galinos 1999 97.16th Pancyprian Medical Conference, 1998 98.35th Panhellenic Pediatric Conference, 1997 99.8th Allergiological Symposium, Nicosia 1996 100.International Conference on Prenatal Medicine, 1996 101.23rd Conference of the Union on Pediatric Companies of the Middle East and Mediterranean, 1996 102.1st Conference of the European Pediatric and Neurological Company and the European

16/12/2020 European Medicine Agency Page 19/21 Pediatric Neurosurgery Company 103.33rd Panhellenic Pediatric Conference, 1995 104.5th International Symposium of Pediatric Company of Cyprus, 1994 105.13th Postgraduate Seminar on Pediatrics, 1993 106.30th Panhellenic Pediatric Conference, 1992 107.National Conference of Encephalic Paralysis, 1991 108.5th Seminar on Emergency and Intensive Pediatrics, 1991 109.4th Seminar on Newborns, 1991 110.3rd Yearly Seminar on Pediatric Hematology, 1990 111.23rd Pediatric Therapeutic Informative Meeting, 1990 112.28th Panhellenic Pediatric Conference, 1990 113.17th Conference on the Union of Pediatric Companies of Middle East and Mediterranean, 1990 114.8th Seminar on Genetic Medicine, 1989 115.2nd Annual Seminar on Pediatric Hematology, 1989 116.22nd Pediatric Therapeutic Informative Meeting, 1989 117.27th Panhellenic Pediatric Conference, 1989 118.International Seminar on Newborns, 1989

Other Relevant Information REVIEWER Reviewer of European Medicine Agency on Public health communication documents i.Referral procedure for metoclopramide-containing medicines (23/07/2013). ii.Referral procedure for codeine-containing medicines (26/06/2013).

Reviewer for Archives of Disease in Childhood. "Does prompt treatment of urinary tract infection in pre-school children prevent renal scarring: mixed retrospective and prospective audits". Reviewer for Archives of Disease in Childhood. "Guidelines to identify abnormalities after childhood urinary tract infections: a prospective audit". Reviewer for BMC Public Health. http://www.biomedcentral.com/ Reviewer of the 2nd Congress of the European Academy of Paediatrics- EAP, Nice, France 2008. Reviewer of the 3rd Congress of the European Academy of Paediatrics- EAP, Copenhagen, Denmark 2010.

OTHER SCIENTIFIC ACTIVITIES

1.Scientific director of the web page www.paidiatros.com which consists substantially of two totally different web pages. The first web page is directed toward the parents and the second is directed toward pediatricians. It is the official web page of the Pediatric Company of Cyprus. Has on average of 11,000-12,000 different visitors per month and about 300,000 hits per month. 2.Member of the Scientific Committee for the organization of the Pan-European Conference of Pediatrics (Europediatrics) 2008. In this committee there are 15 professors and pediatricians from all over Europe. A maximum of only one professor or doctor can participate from any one country. 3.Member of the National Committee Environment and Child Health. Appointed on 30 January 2004 and reappointed in May 2007 for another three years. This committee is appointed by the Council of Ministers with the following mandate: Prepares and coordinates the implementation of the National Action Scheme. Advises the Minister of Health in matters related to legislation and other procedures. It is the contact point of the National Point of Reference for the cooperation regarding the Environment-Child Health with the European Union, the World Health Organization and the other International Organizations. 4.Member of the committee Innovations in the Ministry of Health. This committee is appointed by the Minister of Health. Its purpose is to advice the Minister in matters such as: New tendencies in Medical Science and Public Health New therapies

16/12/2020 European Medicine Agency Page 20/21 Cooperations with centers and scientists abroad Etc 5.Committee for the review of the Booklet of Childs Health. Participated in the committee that reviewed and created the new booklet on childs health which was published in 2007. 6.Represented Cyprus in the European Academy of Pediatricians from 1999 to date. In this body there is only one representative from every nation of the European Union. Its task is, among other things, to accomplish the following: Streamline the political and strategic health tasks in the countries of the European Union Establishment of necessary criteria regarding sub-specialties in pediatrics Promotion of legislation at the European Union level regarding pediatric health Etc 7.Since 2005, member of the Executive Council of the European Academy of Pediatrics. Represent the Secondary Care for all the nations of the European Union. Secretary General of the European Academy of Paediatrics since December 2012 8.Member of the Cyprus Pediatric Association since 1994. Member of the Executive Council of the Pediatric Company of Cyprus since 1998 and Secretary since 2005. 9.Member of the scientific team for the support of the organization of the Association ADD-ADHD SUPPORT Cyprus.

CONFERENCE ORGANIZATION

Member of the organizational committee of many conferences including: 1.Cyprus Presidency Conference. Human Biomonitoring: Linking Environment to Health and Supporting Policy, Larnaca 22-25 October 2012 2.Pediatric meeting. Pediatric Clinic of Larnaca Hospital. Sandy Beach 21st of June 2008. 3.3rd Europediatrics 2008. June 14-17, Turkey 4.1st Pancyprian Conference for Parents and Teachers. Latsia, 5 April 2008, Nicosia 5.10-12 May. CESP meeting 2007. Cyprus 2007 6.10th Pancyprian Pediatric Congress. Challenges from Childhood to Adolescence. 10-11 November 2007 7.Developing the Possibilities of Effective Prevention and Diagnosis of the Effects of the Environment on the Health of the Child. Nicosia 8th December 2006 8.9th Pancyprian Pediatric Conference. Nicosia 25-26 November 2006 9.8th International Symposium of Pediatrics. Paphos 27-28 October 2006 10.8th Pancyprian Pediatric Conference. Nicosia 19-20 November 2005 11.7th Post-graduate Seminar in Pediatrics. Nicosia 2005 12.2nd Pancyprian Conference of Sub-specialties in Pediatrics. Limassol 26-27 February 2005

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