G C A T T A C G G C A T genes Article Frameshift Variant in MFSD12 Explains the Mushroom Coat Color Dilution in Shetland Ponies Jocelyn Tanaka 1 , Tosso Leeb 2 , James Rushton 3, Thomas R. Famula 4, Maura Mack 1, Vidhya Jagannathan 2 , Christine Flury 5, Iris Bachmann 6, John Eberth 7, Sue M. McDonnell 8, Maria Cecilia T. Penedo 1 and Rebecca R. Bellone 1,9,* 1 Veterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, CA 95616, USA;
[email protected] (J.T.);
[email protected] (M.M.);
[email protected] (M.C.T.P.) 2 Institute of Genetics, University of Bern, 3001 Bern, Switzerland;
[email protected] (T.L.);
[email protected] (V.J.) 3 Rowe Equine Ltd, Wotton Under Edge, GLOS GL12 7PP, UK;
[email protected] 4 Department of Animal Science, University of California, One Shields Ave, Davis, CA 95616, USA;
[email protected] 5 School of Agricultural Forest and Food Sciences, Bern University of Applied Sciences, 3052 Zollikofen, Switzerland; christine.fl
[email protected] 6 Agroscope, Swiss National Stud Farm, 1580 Avenches, Switzerland;
[email protected] 7 College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY 40546, USA;
[email protected] 8 Havemeyer Equine Behavior Program, University of Pennsylvania School of Veterinary Medicine, New Bolton Center Department of Clinical Studies, Kennett Square, PA 19348, USA;
[email protected] 9 Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA * Correspondence:
[email protected]; Tel.: +1(530)-752-9299 Received: 30 September 2019; Accepted: 17 October 2019; Published: 19 October 2019 Abstract: Mushroom is a unique coat color phenotype in Shetland Ponies characterized by the dilution of the chestnut coat color to a sepia tone and is hypothesized to be a recessive trait.