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Chapter 4: Assessing the Threat of Genetic Erosion
Chapter 4: Assessing the threat of genetic erosion P. Mathur Bioversity International Sub-Regional Office for South Asia ew Delhi, India E-mail: [email protected] Abstract The world community has confirmed its commitment to the conservation of plant genetic resources that provide valuable traits for meeting the challenges of the future, such as adapting crops to changing climatic conditions or disease outbreaks. However, this plant diversity is threatened by “genetic erosion”, a term coined by scientists for the loss of individual genes or combinations of genes, such as those found in locally adapted landraces. One of the main causes of genetic erosion is the replacement of local varieties by modern varieties. Other causes include environmental degradation, urbanization and land clearing through deforestation and bush fires. Genetic erosion can also occur on the level of germplasm collections and genebanks due to improper management and inadequate regeneration procedures. There is a need to strengthen the conservation and sustainable use of plants and seed systems, and the crucial linkages between them, through a combination of appropriate policies, use of scientific information, farmers’ knowledge, and action. Traditionally, efforts to counter genetic erosion have concentrated on conserving seeds in crop genebanks ( ex situ ). Today, it has become clear that the best strategy combines ex situ conservation with on-the-ground ( in situ ) conservation by farmers in their agro-ecosystems and of crop wild relatives in, for example, areas protected for their environmental value. While such mechanisms are vital, the sustainable use of plant genetic resources is likewise essential because plant genetic diversity increases options and provides insurance against future adverse conditions, such as extreme and variable environments. -
Genetic and Demographic Dynamics of Small Populations of Silene Latifolia
Heredity (2003) 90, 181–186 & 2003 Nature Publishing Group All rights reserved 0018-067X/03 $25.00 www.nature.com/hdy Genetic and demographic dynamics of small populations of Silene latifolia CM Richards, SN Emery and DE McCauley Department of Biological Sciences, Vanderbilt University, PO Box 1812, Station B, Nashville, TN 37235, USA Small local populations of Silene alba, a short-lived herbac- populations doubled in size between samples, while others eous plant, were sampled in 1994 and again in 1999. shrank by more than 75%. Similarly, expected heterozygosity Sampling included estimates of population size and genetic and allele number increased by more than two-fold in diversity, as measured at six polymorphic allozyme loci. individual populations and decreased by more than three- When averaged across populations, there was very little fold in others. When population-specific change in number change between samples (about three generations) in and change in measures of genetic diversity were considered population size, measures of within-population genetic together, significant positive correlations were found be- diversity such as number of alleles or expected hetero- tween the demographic and genetic variables. It is specu- zygosity, or in the apportionment of genetic diversity within lated that some populations were released from the and among populations as measured by Fst. However, demographic consequences of inbreeding depression by individual populations changed considerably, both in terms gene flow. of numbers of individuals and genetic composition. Some Heredity (2003) 90, 181–186. doi:10.1038/sj.hdy.6800214 Keywords: genetic diversity; demography; inbreeding depression; gene flow Introduction 1986; Lynch et al, 1995), the interaction of genetics and demography could also influence population persistence How genetics and demography interact to influence in common species, because it is generally accepted that population viability has been a long-standing question in even many abundant species are not uniformly distrib- conservation biology. -
Evolution, Dynamic Expression Changes and Regulatory Characteristics of Gene Families Involved in the Glycerophosphate Pathway O
www.nature.com/scientificreports OPEN Evolution, dynamic expression changes and regulatory characteristics of gene families Received: 2 October 2018 Accepted: 14 August 2019 involved in the glycerophosphate Published: xx xx xxxx pathway of triglyceride synthesis in chicken (Gallus gallus) Liyu Yang1, Ziming Liu1, Kepeng Ou2, Taian Wang1, Zhuanjian Li1,3,4, Yadong Tian1,3,4, Yanbin Wang1,3,4, Xiangtao Kang1,3,4, Hong Li1,3,4 & Xiaojun Liu1,3,4 It is well documented that four gene families, including the glycerophosphate acyltransferases (GPATs), acylglycerophosphate acyltransferases (AGPATs), lipid phosphate phosphohydrolases (LPINs) and diacylglycerol acyltransferases (DGATs), are involved in the glycerophosphate pathway of de novo triglyceride (TG) biosynthesis in mammals. However, no systematic analysis has been conducted to characterize the gene families in poultry. In this study, the sequences of gene family members in the glycerophosphate pathway were obtained by screening the public databases. The phylogenetic tree, gene structures and conserved motifs of the corresponding proteins were evaluated. Dynamic expression changes of the genes at diferent developmental stages were analyzed by qRT-PCR. The regulatory characteristics of the genes were analyzed by in vivo experiments. The results showed that the GPAT, AGPAT and LPIN gene families have 2, 7 and 2 members, respectively, and they were classifed into 2, 4 and 2 cluster respectively based on phylogenetic analysis. All of the genes except AGPAT1 were extensively expressed in various tissues. Estrogen induction upregulated the expression of GPAM and AGPAT2, downregulated the expression of AGPAT3, AGPAT9, LPIN1 and LPIN2, and had no efect on the expression of the other genes. These fndings provide a valuable resource for further investigation of lipid metabolism in liver of chicken. -
Distinguishing Pleiotropy from Linked QTL Between Milk Production Traits
Cai et al. Genet Sel Evol (2020) 52:19 https://doi.org/10.1186/s12711-020-00538-6 Genetics Selection Evolution RESEARCH ARTICLE Open Access Distinguishing pleiotropy from linked QTL between milk production traits and mastitis resistance in Nordic Holstein cattle Zexi Cai1*†, Magdalena Dusza2†, Bernt Guldbrandtsen1, Mogens Sandø Lund1 and Goutam Sahana1 Abstract Background: Production and health traits are central in cattle breeding. Advances in next-generation sequencing technologies and genotype imputation have increased the resolution of gene mapping based on genome-wide association studies (GWAS). Thus, numerous candidate genes that afect milk yield, milk composition, and mastitis resistance in dairy cattle are reported in the literature. Efect-bearing variants often afect multiple traits. Because the detection of overlapping quantitative trait loci (QTL) regions from single-trait GWAS is too inaccurate and subjective, multi-trait analysis is a better approach to detect pleiotropic efects of variants in candidate genes. However, large sample sizes are required to achieve sufcient power. Multi-trait meta-analysis is one approach to deal with this prob- lem. Thus, we performed two multi-trait meta-analyses, one for three milk production traits (milk yield, protein yield and fat yield), and one for milk yield and mastitis resistance. Results: For highly correlated traits, the power to detect pleiotropy was increased by multi-trait meta-analysis com- pared with the subjective assessment of overlapping of single-trait QTL confdence intervals. Pleiotropic efects of lead single nucleotide polymorphisms (SNPs) that were detected from the multi-trait meta-analysis were confrmed by bivariate association analysis. The previously reported pleiotropic efects of variants within the DGAT1 and MGST1 genes on three milk production traits, and pleiotropic efects of variants in GHR on milk yield and fat yield were con- frmed. -
Crop Genetic Resources Bulletin Number 2 an Economic Appraisal May 2005 Kelly Day Rubenstein, Paul Heisey, Robbin Shoemaker, John Sullivan, and George Frisvold
A Report from the Economic Research Service United States Department www.ers.usda.gov of Agriculture Economic Information Crop Genetic Resources Bulletin Number 2 An Economic Appraisal May 2005 Kelly Day Rubenstein, Paul Heisey, Robbin Shoemaker, John Sullivan, and George Frisvold Abstract: Crop genetic resources are the basis of agricultural production, and significant economic benefits have resulted from their conservation and use. However, crop genetic resources are largely public goods, so private incentives for genetic resource conservation may fall short of achieving public objectives. Within the U.S. germplasm system, certain crop collec- tions lack sufficient diversity to reduce vulnerability to pests and diseases. Many such genetic resources lie outside the United States. This report examines the role of genetic resources, genetic diversity, and efforts to value genetic resources. The report also evaluates economic and institutional fac- tors influencing the flow of genetic resources, including international agree- ments, and their significance for agricultural research and development in the United States. Keywords: Genetic resources, genetic diversity, germplasm, R&D, interna- tional transfer of genetic resources, in situ conservation, ex situ conserva- tion, gene banks, intellectual property. Acknowledgments: The authors wish to thank Allan Stoner, Henry Shands, and Peter Bretting for their thoughtful reviews and their valuable comments. Thanks for reviews above and beyond the call of duty belong to June Blalock, whose patience and insight were critical to the production of this report. We also thank Joe Cooper who reviewed portions of the manuscripts. Keith Wiebe provided helpful guidance in the development of the final draft. We thank Dale Simms for his excellent editorial work and Susan DeGeorge for her help with graphics and layout. -
UNIVERSITY of CALIFORNIA, SAN DIEGO Early Signaling in Plant
UNIVERSITY OF CALIFORNIA, SAN DIEGO Early Signaling in plant immunity A dissertation submitted in partial satisfaction of the requirements for the degree Doctor of Philosophy in Biology by Tenai E. Eguen Committee in charge: Professor Steven Briggs, Chair Professor Marty Yanofsky, Co-Chair Professor Tracy Johnson Professor Bernhard Palsson Professor Yunde Zhao 2013 Copyright Tenai E. Eguen, 2013 All rights reserved The Dissertation of Tenai E. Eguen is approved, and it is acceptable in quality and form for publication on microfilm and electronically: _______________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ ________________________________________________________________________ Chair University of California, San Diego 2013 iii DEDICATION This dissertation is dedicated to all my friends and family who were supportive during my graduate studies. It is also dedicated to all the students, colleagues and my committee members who contributed to the success of this research. iv TABLE OF CONTENTS Signature Page ................................................................................................................................ iii Dedication ....................................................................................................................................... iv Table of Contents ............................................................................................................................ -
Contemporary Agriculture Vol
Contemporary Agriculture Vol. 67, No. 1, Pp. 1 - 8, 2018. The Serbian Journal of Agricultural Sciences ISSN (Online) 2466-4774 UDC: 63(497.1)(051)-“540.2” www.contagri.info Review paper UDC: 582.542.11 DOI: 10.2478/contagri-2018-0001 AGROBIODIVERSITY GENETIC VARIABILITY UTILIZATION IN ORGANIC FOOD PRODUCTION* Miodrag DIMITRIJEVIĆ1♦, Sofija PETROVIĆ, Borislav BANJAC, Goran BARAĆ, Velimir MLADENOV1 Summary The food production at the global level is about to meet its border. Industrialization of agriculture correlates with an explosive enlargement of human population, during XX and at the beginning of XXI centuries. An ongoing process of environmental erosion has been speeding up during that period, not only in our physical surrounding, but also in biodiversity. A new direction in agricultural food production is in demand. Organic food production has been recognized as the way of providing safety and quality food, preserving the environment in the same time. In the other hand new land areas have to be explored for agricultural use, in order to enhance food quantity to meeting the increasing demand for food. These targets set new requirements in plant breeding. To fulfill these requirements the genetic variability harbored in genetic resources has to be preserved, examined and put to good use. Key words: biodiversity, organic, agriculture, genetics, breeding, agriculture INTRODUCTION The human population is growing in a burst. The World entered 20th Century with about 1.5 billion inhabitants, and left it enriched by more than 6 billion. In just 100 years the increment was three time bigger than in all previous human history. At the moment there is more than 7 billion of us, as UN reported, summarized by Roser and Ortiz- Ospina (2017). -
Diversity on the Farm How Traditional Crops Around the World Help to Feed Us All, and Why We Should Reward the People Who Grow Them
Diversity on the Farm How traditional crops around the world help to feed us all, and why we should reward the people who grow them. FORD FOUNDATION By Charles C. Mann POLITICAL ECONOMY RESEARCH INSTITUTE UNIVERSITY OF MASSACHUSETTS Maize Front cover, left: Hector Diaz Castellano, a Zapotec small-holder, on his farm in the hills of southern Mexico; right: an array of native maize varieties. Above and right: Post-harvest survey of native maize varieties at INIFAP, an agricultural-research institute outside the city of Oaxaca; inside left: making the maize drink atole in a country market; inside right: rinsing off the lime used to process maize kernels for hand-made tortillas in Ítanoni, an unusual gourmet tortillería in Oaxaca city that may serve as one model for saving agricultural biodiversity. By Charles C. Mann Photographs by Peter Menzel Diversity on the Farm Subhead if any goes here for the development of wild corn and Maize heirloom varieties At Ítanoni, hand-made tortillas 2 Mission Statements 17 From the Stomach 23 The Best Tortillas from single varieties of native maize to the Heart in Mexico are cooked on traditional circular 3 Foreword clay griddles called comales. 25 Notes 5 Introduction 19 What We Can Do: Five Approaches 28 Credits 7 Building the Roof with 1. LABELING Stones from the Foundation 2. CROP IMPROVEMENT 3. REMOVING PERVERSE INCENTIVES 11 Conserving Agricultural Biodiversity 4. PAYING FOR CURRENTLY Copyright 2004 UNCOMPENSATED SERVICES by the Ford Foundation all rights reserved. 13 A Community Effort 5. INCREASING SOCIAL CAPITAL Mission Statements FORD FOUNDATION The Ford Foundation is a resource for innovative people and institutions worldwide. -
Genetic Erosion of Agrobiodiversity in India and Intellectual Property Rights: Interplay and Some Key Issues
Genetic Erosion of Agrobiodiversity in India and Intellectual Property Rights: Interplay and some Key Issues Sabuj Kumar Chaudhuri [SRF (UGC) NET], Department of Library and Information Science, Jadavpur University, Kolkata-32 [West Bengal], India. email: [email protected] Abstract Agrobiodiversity is the backbone of a nation’s food security and the basis of economic development as a whole. Over the years this diversity in India is under pressure due to the massive commercialisation of agriculture leading to the almost extinction of traditional farming systems. The top-down system of agricultural research, where farmers are seen merely as recipients of research rather than as participants in it, has contributed to an increased dependence on a relatively few plant varieties. This trend and the increasing industrialization of agriculture are key factors in what can only be called "genetic erosion". The term refers to both the loss of species and the reduction of variety. Behind this commercialization there lies the interest of the breeders for obtaining intellectual property rights. It has a very complicated relationship with this diversity. The paper highlights this relationship and provides some suggestions in order to rectify the current negative phenomenon. India’s agrobiodiversity is most significant one in the world. This diversity is the result of thousand of years of farmer’s selection, experimentation (even cross breeding) and propagation of desirable traits of desirable species in innumerable ways for their subsistence and cultural purposes. Over the years this unparallel diversity of various crops of India has been eroded. Replacement of landraces (a crop cultivar that evolved with and has been genetically improved by traditional agriculturists, but has not been influenced by modern breeding practices) or TVs (traditional varieties) by MVs (modern varieties) or HYVs (High Yielding Varieties) is one of the most important reasons. -
35Th International Society for Animal Genetics Conference 7
35th INTERNATIONAL SOCIETY FOR ANIMAL GENETICS CONFERENCE 7. 23.16 – 7.27. 2016 Salt Lake City, Utah ABSTRACT BOOK https://www.asas.org/meetings/isag2016 INVITED SPEAKERS S0100 – S0124 https://www.asas.org/meetings/isag2016 epigenetic modifications, such as DNA methylation, and measuring different proteins and cellular metab- INVITED SPEAKERS: FUNCTIONAL olites. These advancements provide unprecedented ANNOTATION OF ANIMAL opportunities to uncover the genetic architecture GENOMES (FAANG) ASAS-ISAG underlying phenotypic variation. In this context, the JOINT SYMPOSIUM main challenge is to decipher the flow of biological information that lies between the genotypes and phe- notypes under study. In other words, the new challenge S0100 Important lessons from complex genomes. is to integrate multiple sources of molecular infor- T. R. Gingeras* (Cold Spring Harbor Laboratory, mation (i.e., multiple layers of omics data to reveal Functional Genomics, Cold Spring Harbor, NY) the causal biological networks that underlie complex traits). It is important to note that knowledge regarding The ~3 billion base pairs of the human DNA rep- causal relationships among genes and phenotypes can resent a storage devise encoding information for be used to predict the behavior of complex systems, as hundreds of thousands of processes that can go on well as optimize management practices and selection within and outside a human cell. This information is strategies. Here, we describe a multi-step procedure revealed in the RNAs that are composed of 12 billion for inferring causal gene-phenotype networks underly- nucleotides, considering the strandedness and allelic ing complex phenotypes integrating multi-omics data. content of each of the diploid copies of the genome. -
OUR HOUSE DESIGNS ACTIVE LEATHER / FABRIC LIST - OCTOBER MARKET 2018 Listed Below Are All Leathers That Are Active
OUR HOUSE DESIGNS ACTIVE LEATHER / FABRIC LIST - OCTOBER MARKET 2018 Listed below are all leathers that are active. Please remove swatches that are not on this list. * REGULAR LEATHERS * Leather # Color Name Leather # Color Name Leather # Color Name 302A-51 Cherry 382A-71 Teal 404P-85 Tigers Eye 305A-81 Brown 383A-21 Citron 404P-86 Fudgesicle 333N-11 Storm Cloud 388A-81 Espresso 404P-87 Nutmeg 349A-71 Peacock 390N-81 Longhorn 406A-11 Ash 350A-71 Bell Pepper 398A-21 Sand 410A-11 Stone 351A-11 Ivory 398A-62 Black 412A-81 Dark Rum 351A-61 Crystal 398A-71 Hazy 416A-11 Mist 356A-81 Mulch 399P-81 Coconut Husk 416A-31 Heaven 357A-81 Terra 400P-11 Moon Dust 417A-31 Spa 359AC-21 Camel 400P-61 Asphalt 424A-61 Black 359AC-31 Sailor 400P-62 Ashe 425A-11 Hand Wipe 359AC-51 Cherry Red 400P-82 Umber 466A-82 Saddle 359AC-52 Brick 401A-31 Sapphire 490A-83 Wolf 359AC-61 Midnight 401A-71 Evergreen 494P-11 Opalite 359AC-62 Smoke 402N-31 Sailboat 494P-13 Sandstone 359AC-71 Fern 402N-61 Slate 494P-61 Flagstone 359AC-72 Aqua 402N-81 Molasses 494P-62 Agate 359AC-81 Tundra 403N-31 Dark Blue 494P-81 Bronzite 359AC-82 Milk Chocolate 404P-11 Shale 494P-82 Tiger Eye 359AC-83 Tile 404P-12 Cobblestone 494P-83 Marble 359AC-84 Hazy 404P-13 Malt 495P-11 Mink 359AC-85 Espresso 404P-14 Chantillie 495P-61 Lynx 369A-11 Hand Glazed 404P-21 Cider 522A-81 Brown 371P-11 Shadow 404P-31 Azure 524A-61 Hazy Black 371P-81 Mud Cakes 404P-32 Oceanic 531A-61 Fog 373P-11 Starlight 404P-52 Red Velvet 531A-81 Cashew 373P-12 Fog 404P-53 Bitters 531A-83 Espresso 378A-81 Pecan 404P-61 Heather -
Snomed Ct Dicom Subset of January 2017 Release of Snomed Ct International Edition
SNOMED CT DICOM SUBSET OF JANUARY 2017 RELEASE OF SNOMED CT INTERNATIONAL EDITION EXHIBIT A: SNOMED CT DICOM SUBSET VERSION 1.