PRODUCT DATA SHEET Bioworld Technology,Inc.

DDX50 polyclonal antibody

Catalog: BS71842 Host: Rabbit Reactivity: Human,Mouse,Rat

BackGround: by affinity-chromatography using epitope-specific im- DEAD box proteins, characterized by the conserved motif munogen and the purity is > 95% (by SDS-PAGE). Asp-Glu-Ala-Asp (DEAD), are putative RNA . Applications: They are implicated in a number of cellular processes in- WB 1:200 - 1:2000 volving alteration of RNA secondary structure such as IHC 1:50 - 1:200 translation initiation, nuclear and mitochondrial splicing, IF1:50 - 1:200 and ribosome and spliceosome assembly. Based on their Storage&Stability: distribution patterns, some members of this DEAD box Store at 4°C short term. Aliquot and store at -20°C long protein family are believed to be involved in embryogen- term. Avoid freeze-thaw cycles. esis, spermatogenesis, and cellular growth and division. Specificity: This encodes a DEAD box that may be in- DDX50 polyclonal antibody detects endogenous levels of volved in ribosomal RNA synthesis or processing. This DDX50 protein. gene and DDX21, also called RH-II/GuA, have similar DATA: genomic structures and are in tandem orientation on 10, suggesting that the two arose by in evolution. This gene has on 2, 3 and 4. of this gene generates multiple transcript variants, but the full length nature of all the other variants but one has not been defined. Product: Western blot analysis of extracts of various cell lines, using DDX50 an- Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, tibody at 1:3000 dilution. 50% glycerol, pH7.2 Note: Molecular Weight: For research use only, not for use in diagnostic procedure. 105kDa Swiss-Prot: Q9BQ39 Purification&Purity: The antibody was affinity-purified from rabbit antiserum

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