Cyberknife Boost for Patients with Cervical Cancer Unable to Undergo Brachytherapy
ORIGINAL RESEARCH ARTICLE published: 21 March 2012 doi: 10.3389/fonc.2012.00025 CyberKnife boost for patients with cervical cancer unable to undergo brachytherapy Jonathan Andrew Haas 1*, Matthew R. Witten2, Owen Clancey 2, Karen Episcopia2, Diane Accordino1 and Eva Chalas 3 1 Division of Radiation Oncology, Winthrop-University Hospital, Mineola, NY, USA 2 Division of Medical Physics, Winthrop-University Hospital, Mineola, NY, USA 3 Division of Gynecologic Oncology, Winthrop-University Hospital, Mineola, NY, USA Edited by: Standard radiation therapy for patients undergoing primary chemosensitized radiation for Brian Timothy Collins, Georgetown carcinomas of the cervix usually consists of external beam radiation followed by an intra- Hospital, USA cavitary brachytherapy boost. On occasion, the brachytherapy boost cannot be performed Reviewed by: Sean Collins, Georgetown University due to unfavorable anatomy or because of coexisting medical conditions. We examined the Hospital, USA safety and efficacy of using CyberKnife stereotactic body radiotherapy (SBRT) as a boost Brian Timothy Collins, Georgetown to the cervix after external beam radiation in those patients unable to have brachytherapy Hospital, USA to give a more effective dose to the cervix than with conventional external beam radiation *Correspondence: alone. Six consecutive patients with anatomic or medical conditions precluding a tandem Jonathan Andrew Haas, Division of Radiation Oncology, and ovoid boost were treated with combined external beam radiation and CyberKnife boost Winthrop-University Hospital, 264 Old to the cervix. Five patients received 45 Gy to the pelvis with serial intensity-modulated radi- Country Road, Mineola, NY 11501, ation therapy boost to the uterus and cervix to a dose of 61.2Gy.These five patients received USA.
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