Royal Free Sheila Sherlock Virtual Postgraduate Course 2021

Wed 24th March – Fri 26th March 2021

Day 1: Hepatology in the clinic

09.00-09.15 Opening welcome (Prof Massimo Pinzani) & Course introduction (Dr Nekisa Zakeri)

Each talk 20mins (+ 5mins for Q&As)

Session 1: Liver disease & Lifestyle. Chair: Prof Massimo Pinzani. 09.15-09.40 Alcohol-related liver disease (Prof Kevin Moore) 09.40-10.05 Non-alcoholic fatty liver disease (Dr Penny Manousou) 10.05-10.10 Discussion/interval 10.10-10.35 NAFLD: risk stratification & streamlining referrals (Prof Emmanuel Tsochatzis)

10.35-10.55 Coffee Break

Session 2: Viral & hereditary liver diseases. Chair: Dr Doug Macdonald. 10.55-11.20 Hepatitis B (Dr Doug Macdonald) 11.20-11.45 Hepatitis C (Prof William Rosenberg) 11.45-11.50 Discussion/interval 11.50-12.15 Hyperferritinaemia & hereditary haemochromatosis (Dr James Dooley)

12.15-13.00 Lunch Break

Section 3: Radiology & liver lesions. Chair: Dr Aileen Marshall. 13.00-13.25 Radiology cases (Dr Dominic Yu) 13.25-13.50 (Dr Aileen Marshall) 13.50-13.55 Discussion/interval 13.55-14.20 Immunotherapy-related liver complications (Dr Doug Macdonald)

14.20-14.40 Coffee Break

Session 4: Autoimmune liver diseases. Chair: Prof Doug Thorburn. 14.40-15.05 Primary Biliary Cholangitis (Prof Doug Thorburn) 15.05-15.30 (Dr Jon Potts) 15.30-15.40 Discussion/interval

Session 5: Pancreato-Biliary & hereditary liver diseases. Chair: Dr Jon Potts. 15.40-16.05 Primary Sclerosing Cholangitis (Prof Steve Pereira) 16.05-16.30 Wilson’s disease (Dr James Dooley)

16.30 Closing remarks

Day 2: Hepatology on the acute take

08.50-09.00 Opening welcome (Prof Massimo Pinzani)

Each talk 20mins (+ 5mins for Q&As)

Session 1: Cirrhosis & its complications. Chair: Prof Emmanuel Tsochatzis. 09.00-09.25 Cirrhosis: disease trajectory & ACLF (Prof Rajiv Jalan) 09.25-9.50 Ascites, SBP, Renal dysfunction (Prof Emmanuel Tsochatzis) 09.50-09.55 Discussion/interval 09.55-10.20 (Dr Jane MacNaughtan)

10.20-10.40 Coffee Break

Session 2: Cirrhosis & its complications. Chair: Dr David Patch. 10.40-11.05 Role of albumin in cirrhosis (Prof Alastair O’Brien) 11.05-11.30 Variceal bleeding (Prof Raj Mookerjee) 11.30-11.40 Discussion/interval 11.40-12.05 Variceal bleeding: ‘TIPSS & tricks’ (Dr David Patch)

12.05-12.50 Lunch break

Session 3: Sheila Sherlock Hepatology Symposium 2021. Chair: Prof Rajiv Jalan. 12.50-13.15 Sheila Sherlock Invited Lecture: Alcoholic hepatitis (Prof Philippe Mathurin) 13.15-13.55 Debate: ‘use of steroids in severe alcoholic hepatitis’ (Prof Philippe Mathurin vs. Prof Mark Thursz)

13.55-14.15 Coffee Break

Session 4: Challenging presentations of liver disease. Chair: Prof Massimo Pinzani. 14.15-14.45 Interactive Grand Round: Vascular liver diseases (Dr David Patch) 14.45-15.10 Drug induced liver injury (Prof Massimo Pinzani) 15.10-15.20 Discussion/interval

Session 5: Challenging presentations of liver disease. Chair: Dr Rachel Westbrook. 15.20-15.45 Deranged LFTs in pregnancy (Dr Rachel Westbrook) 15.45-16.10 Covid-19 & liver disease (Dr Gautam Mehta) 16.10-16.35 Covid-19: impact on liver services & (Dr Aileen Marshall)

16.35 Closing remarks

Day 3: Hepatology in the ICU & Liver transplantation

08.50-09.00 Opening welcome (Prof Massimo Pinzani)

Each talk 20mins (+ 5mins for Q&As)

Session 1: The sick liver patient. Chair: Dr Jennifer Ryan. 09.00-09.25 Escalation decisions & ceilings of care (Dr Philip Berry) 09.20-09.50 Acute liver failure (Dr Jennifer Ryan) 09.50-10.00 Discussion/interval

Session 2: Challenging presentations of liver disease. Chair: Dr Marsha Morgan. 10.00-10.25 Sarcopenia & nutrition in liver disease (Dr Marsha Morgan) 10.25-10.55 Thinking forward in liver disease: integrating palliative care (Dr Heather Lewis, Dr Philip Lodge)

10.55-11.15 Coffee Break

Session 3: Liver Transplantation: pre-transplant. Chair: Dr Rachel Westbrook. 11.15-11.40 Who & when to refer for liver transplantation? (Dr Rachel Westbrook) 11.40-12.05 Liver transplantation from retrieval to surgery (Prof Brian Davidson) 12.05-12.10 Discussion/interval

Session 4: Liver Transplantation: post-transplant. Chair: Dr Aileen Marshall. 12.10-12.35 Post-transplant care & complications: case discussions (Dr Aileen Marshall)

12.35 Closing statements (Prof Massimo Pinzani)