The Quality of Care Among Older Adults with Diabetes Comorbid with Other Chronic Conditions
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The quality of care among older adults with diabetes comorbid with other chronic conditions by Yelena Petrosyan A thesis submitted in conformity with the requirements for the degree of Doctor of Philosophy (PhD) Institute of Health Policy, Management & Evaluation University of Toronto © Copyright by Yelena Petrosyan 2017 The quality of care among older adults with diabetes comorbid with other chronic conditions Yelena Petrosyan Doctor of Philosophy Institute of Health Policy, Management and Evaluation University of Toronto 2017 Abstract The management of people with multiple chronic conditions requires understanding the extent to which concurrent chronic conditions contribute and interact to affect the patient’s health status, as well as assessing the risk and benefits of various strategies for the treatment of complex needs in patients. A single condition focus in both clinical care and research remains and limits the assessment of care for people with multiple chronic conditions. The overall aim of this project was to evaluate the quality of overall care for older adults with selected disease combinations in ambulatory care settings. The first study aimed to identify a set of evidence-based and valid quality indicators for evaluating ambulatory care for older adults with selected chronic conditions, including diabetes, hypertension, chronic ischemic heart disease, major depression and osteoarthritis. The second study aimed to critically appraise the identified quality indicators and select a set of indicators for evaluating the quality of care for older adults with diabetes with comorbid concordant and discordant chronic conditions. The third study aimed to examine the difference in the quality of care between patients with 2 vs. 1 selected concordant vs. discordant comorbid conditions, and to examine associations of quality of care and hospitalizations among older adults with selected disease combinations. The study findings suggest that older adults with diabetes are at risk of suboptimal care with additional selected comorbid conditions, especially those with discordant comorbid ii conditions. The study findings also support the importance of continuity of care for older diabetes patients with comorbid chronic conditions. The study findings suggest that the likelihood of hospitalizations increases with the number of prescribed drugs among older adults with comorbidities. There is a need for a holistic approach in education and clinical care of older adults with diabetes taking into account concomitant conditions that affect patient’s health status. Future research is needed for measuring the quality of care in the larger diabetes population and reporting by different stratifications, including age, sex, primary care models to see if there are any patterns in certain groups and target the interventions towards improving practices for specific sub groups. iii Acknowledgments I would like to dedicate this work in memory of my mother, Hripsime Baghdasaryan. This work is also dedicated to my father, Rafael Petrosyan and brother, Armen Petrosyan for always supporting, helping, and encouraging me. Despite the fact that we have been living far apart during my graduate studies, their endless support and unconditional love have always been with me through all the ups and downs of this long journey. I would like to sincerely thank my supervisor, Dr. Walter Wodchis for his guidance and mentorship over the past four years. I am also grateful for all of the research opportunities that he exposed me to during past four years. I would like to express my appreciation to my thesis committee members, Dr. Jan Barnsley, Dr. Kerry Kuluski, and Dr. Barbara Liu for providing insightful comments and questions on my research as it developed. I would like to extend my sincere thanks to Yeva Sahakyan, who helped me to accomplish the systematic reviews. I would like to express thanks to Chris Bai and Andrew Calzavara, ICES UofT, for their continuous support. I would like to thank all of the health care providers/researchers who participated in this research. I would like to express sincere thanks to my colleagues and friends from the Toronto Health Economics and Technology Assessment (THETA) Collaborative, UofT, for nurturing environment and support over the past two years. I want to thank the Health System Performance Research Network (HSPRN) for providing me with financial support during my study years. iv Table of Contents Acknowledgments ......................................................................................................................... iv List of Tables ................................................................................................................................. ix List of Figures ............................................................................................................................... xii List of Appendices ....................................................................................................................... xiii CHAPTER 1: Introduction ............................................................................................................. 1 1.1 Chronic conditions, aging and multimorbidity ......................................................................... 1 1.2 Multimorbidity among patients with diabetes .......................................................................... 2 1.3 Multimorbiditiy’s issues/challenges ......................................................................................... 5 1.3.1 Multimorbidity: high health care utilization .............................................................. 5 1.3.2 Management of older adults with multiple chronic conditions ................................. 7 1.3.3 Multimorbidity: implications for primary care .......................................................... 9 1.3.4 Continuity of care .................................................................................................... 11 1.3.4 Quality indicators in health care .............................................................................. 13 1.4 Performance Measurement for People with Multimorbidity: Conceptual model ................... 15 1.5 Summary ................................................................................................................................. 19 1.6 Thesis project outline .............................................................................................................. 20 1.7 Broad project objectives ......................................................................................................... 21 CHAPTER 2: Systematic review of quality indicators for care for older adults with diabetes, hypertension, chronic ischemic heart disease, major depression and osteoarthritis ..................... 24 Abstract ......................................................................................................................................... 24 2.1 Introduction ............................................................................................................................. 26 2.2 Rationale for the study ............................................................................................................ 28 2.3 Study objectives ...................................................................................................................... 30 2.4 Methods .................................................................................................................................. 30 2.4.1 Search strategy ......................................................................................................... 30 2.4.2 Study selection ......................................................................................................... 32 2.4.3 Methodological assessment ..................................................................................... 34 2.4.4 Data extraction ......................................................................................................... 36 2.5 Results ..................................................................................................................................... 37 2.5.1 Systematic review of quality indicators for care for older adults with diabetes ...... 37 2.5.1.1 Search results ........................................................................................................ 37 v 2.5.1.2 Study characteristics ............................................................................................. 38 2.5.1.3 Methodological quality ......................................................................................... 40 2.5.1.4 Quality indicators .................................................................................................. 41 2.5.2 Systematic review of quality indicators for care for older adults with hypertension, and chronic ischemic heart disease ............................................................ 45 2.5.2.1 Search results ........................................................................................................ 45 2.5.2.2 Study characteristics ............................................................................................. 47 2.5.2.3 Methodological quality ......................................................................................... 49 2.5.2.4 Quality indicators .................................................................................................. 50 2.5.2.4.1 Quality