Kazlouskaya V

MINISTRY OF HEALTH OF REPUBLIC OF BELARUS GOMEL STATE MEDICAL UNIVERSITY V. V. Kazlouskaya SELECTED LECTURES ON DERMATOLOGY Manual for foreign medical students Gomel GSMU 2008 УДК 616.5 (075.8)=20 ББК 55.8 К 59 Рецензеты: заведующий кафедрой дерматовенерологии УО «Витебский государственный медицинский университет», доктор медицинских наук, профессор В. П. Адаскевич; заведующий кафедрой поликлинической терапии и общеврачебной практики с курсом дерматовенерологии УО «Гомельский государственный медицинский университет», кандидат медицинских наук, доцент Э. Н. Платошкин. Козловская, В. В. К 59 Курс лекций по дерматологии: учеб.-метод. пособие для студентов- медиков = Selected Lectures on Dermatology: manual for foreign medical students / В. В. Козловская. — Гомель: Учреждение образования «Го- мельский государственный медицинский университет», 2008. — 160 с. ISBN 978-985-506-210-4 Учебно-методическое пособие «Selected Lectures on Dermatology» представляет собой курс лекций по дерматологии, предназначенный для иностранных студентов 3 курса, обучающихся на английском языке. Лекции составлены в соответствии с типовой учебной программой и содержат основные разделы цикла дерматология. Утверждено и рекомендовано к изданию Центральным учебным научно- методическим советом учреждения образования «Гомельский государственный медицинский университет» 20 ноября 2008 г., протокол № 11. УДК 616.5 (075.8) ББК 55.8 ISBN 978-985-506-210-4 © Учреждение образования «Гомельский государственный медицинский университет», 2008 2 Abbreviations Used in the Book AA — alopecia areata HPV — human papiloma virus ACD — allergic contact dermatitis HSV — herpes simplex virus AD — atopic dermatitis IL — interminate leprosy AGA — allergic granulomatous angiitis JEB — junctional epidermolysis AIDS — aquired immunodeficiency bullosa syndrome KS — sarcoma Kaposi ANA — anti-nuclear antibodies LCL — local cutaneous leishmaniasis ANCA — antineutrophil cytoplasmic LDH — lactate dehydrogenase antibodies LE — lupus erythematosus AST — aspartate aminotransferase LGV — lymphogranulomatosis ASO — anti streptococcal O antigen venereal BBL — borderline borderline leprosy LL — lepromatous leprosy BCIE — bullous congenital LP – lichen planus ichthyosiform erythroderma LR — leishmaniasis recidivans BL — lorderline lepromatous leprosy MF — mycosis fungoides BTL — borderline tuberculoid leprosy NBCIE — nonbullous congenital CLE — cutaneous lupus erythematosus ichthyosiform erythroderma CRP — C-reactive protein NSAIDs — non steroid anti- CSF — cerebral spinal fluid inflammatory drugs CSVV — cutaneus small vessel OM — onichomycosis vasculitis PCAS — perifolliculitis capitis CTCL — cutaneous T-cell lymphoma abscedens et suffodiens DCL — dissiminative cutaneous PF — pemphigus foliaceus leishmaniasis PKADL — Post-Kala-Azar DDS — dapsone Dermal leishmaniasis DEB — dystrophic epidermolysis PN — polyarteritis nodosa bullosa PUVA — psoralen plus ultraviolet DH — dermatitis herpetiformic During A therapy DLST — drug lymphocyte stimulating PV — pemphigus vulgaris test RA — rheumatoid arthritis DM — dermatopmyositis SJS — Stevens – Jonson syndrome DNA — deoxyribonuclease SLE — systemic lupus DPCP — diphenylcyclopropenone erythematosus EB — epidermolysis bullosa SS — Sezary syndrome EED — erythema elevatum diutinum TA — temporal arteriitis EM — erythema mygrans TAO — tromboangiitis obliterans EMM — erythema multiforme TEN — toxic epidermolysis ESR — erythrocyte sedimentation rate TL — tuberculoid leprosy GABHS — group of B hemolytic TSEB — total skin electron beam streptococcus VL — visceral leishmaniasis VZV — varicella zoster virus 3 Content Lecture 1. Structure and Functions of the Skin. Main Pathomorphological Processes in the Skin. Principles of the Therapy of Diseases of the Skin................................................................................7 Structure of the Skin ..............................................................................................................................7 Epidermis ........................................................................................................................................7 Dermo-epidermal junction .............................................................................................................8 Derma..............................................................................................................................................9 The subcutaneous tissue (subdermal fatty tissue) .........................................................................9 Cutaneous sensory system ..............................................................................................................9 Cutaneous vessel system ...............................................................................................................10 Sebaceous glands..........................................................................................................................12 Sweet glands..................................................................................................................................13 Nails ..............................................................................................................................................14 Functions of the skin........................................................................................................................17 Dermapathological processes..........................................................................................................17 Principles of the Therapy of Diseases of the Skin. ........................................................................20 Systemic Therapy..........................................................................................................................21 Phototherapy.................................................................................................................................22 Photochemotherapy (PUVA)........................................................................................................22 Cryotherapy...................................................................................................................................22 Laser (Light Amplification by Stimulated Emission of Radiation) ............................................22 Lecture 2. Observation of the Skin Patient (scheme of the case history) ........................................23 Lecture 3. Bacterial Infections of the Skin (Pyodermas). .................................................................32 Staphylococcal Infections ..................................................................................................................32 Folliculitis .....................................................................................................................................32 Boils (Furuncles)..........................................................................................................................33 Hydradenitis Suppurativa.............................................................................................................33 Carbuncles ....................................................................................................................................34 Paronychial Infections .................................................................................................................34 Staphylococcal Scalded Skin Syndrome (Ritter-Lyell Syndrome) ..............................................35 Streptococcal Infections...................................................................................................................36 Impetigo.........................................................................................................................................36 Ecthyma.........................................................................................................................................37 Impetigo angularis (perleche, cheilitis angularis, stomatitis angularis, angular cheilitis) .......37 Pyoderma gangrenosum...............................................................................................................37 Pityriasis alba................................................................................................................................38 Perifolliculitis Capitis Abscedens et Suffodiens (PCAS).............................................................38 Lecture 4. Parasitic Diseases of the Skin............................................................................................40 Scabies...............................................................................................................................................40 Pediculosis.........................................................................................................................................43 Lecture 5. Mycobacterial Infections of the Skin................................................................................45 Tuberculosis of the skin...................................................................................................................45 Lupus vulgaris ..............................................................................................................................46 TB verrucosa cutis ........................................................................................................................47 Scrofuloderma...............................................................................................................................47

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