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CanÅ“rResearch VOLUME 48 •NUMBER 4 •CNREA8•PP759-1048 CONTENTSt Asterisks # preceding page numbers refer to studies using human-derived material. Perspectives in Cancer Research 826 Influence of 1-0-D-ArabinofuranosylcytosineConjugates of Lipids on the Growth and Metastasis of Lewis Lung Carcinoma. 759 Polyamine Metabolism and Its Importance in Neoplasia- Growth Wolfgang E. Berdel, Susanne Danhauser, Chung II Hong, Hans and as a Target for Chemotherapy. Anthony E. Pegg. D. Schick, Anneliese Reichert, Raymonde Busch, Johann Special Lecture Rastetter, and W. Ralph Vogler. 830 Cytoplasmic Suppression of Tumorigenicity in Reconstructed 775 Therapeutic Attack of Hypoxie Cells of Solid Tumors: Presiden Mouse Cells. JerryW. Shay and Harold Werbin. tial Address. Alan C. Salterelli. 834 CGS 16949A, a New Nonsteroidal Animatasi: Inhibitor: Effects on Hormone-dependent and -independent Tumors in Vivo. Klaus BASIC SCIENCES Schieweck, Ajay S. Bhatnagar,and Alex Matter. 779 Inhibition of Estrogen-induced Renal Carcinogenesis in Male Syr 839 Leukemia I 121(1Cell Lines Resistant to Ribonucleotide Reduc ian Hamsters by Tamoxifen without Decrease in DNA Adduct ÃaseInhibitors.Joseph G. Cory and Gay L. Carter. Levels. Joachim G. Liehr, David A. Sirbasku, Elzbieta Jurka, Kurt Randerath, and Erika Randerath. * 844 Biological Significance of Domain-oriented DNA Repair in Xero- derma Pigmentosum Cells. George J. Kantor and Cynthia F. * 784 la Vitro Estrogenic Actions in Rat and Human Cells of Hydrox- Elking. ylated Derivatives of D16726 (Zindoxifene), an Agent with Known 850 TransformingGrowth Factors Produced by Normal and Neoplas- AntimammaryCancer Activity in Vivo. S. P. Robinson, R. Koch, tically TransformedRat Liver Epithelial Cells in Culture.Chi Liu, and V. C. Jordan. Ming-Sound Tsao, and Joe W. Grisham. * 788 Synergy of Tumor Necrosis Factor and Interleukin 2 in the Acti *856 Expression of the Human T-Cell-specific Tyrosine Kinase YTI6 vation of Human Cytotoxic Lymphocytes: Effect of Tumor Necro (lek) Message in Leukemic T-Cell Lines. Yasuhiro Koga, sis Factor a and Interleukin 2 in the Generation of Human Nobuhiro Kimura, Jun Minowada, and Tak W. Mak. Lymphokine-activated Killer Cell Cytotoxicity. Laurie B. Owen- 860 Topoisomerase 11-mediated DNA Damage Produced by 4'-(9- Schaub, Jordan U. Gutterman, and Elizabeth A. Grimm. Acridinylamino)methanesulfon-fn-anisidideand Related Acridines 793 Increased Resistance to rä-Diamminedichloroplatinum(H)inNIH in LI 210 Cells and Isolated Nuclei: Relation to Cytotoxicity. 3T3 Cells Transformed by ras Oncogene*. Marshall D. Sklar. Joseph M. Covey, Kurt W. Kohn, Donna Kerrigan, Eugene J. Tilchen, and Yves Pommier. * 798 Aerobic and Hypoxie Toxicity of a New Class of Mixed-Function *866 Molecular Heterogeneity of Adult Philadelphia Chromosome- Drugs Associating Nitroimidazoles and Chloroethylnitrosourea in Nitrosourea-sensitive (Mer*) and -resistant (Mer* ) Human Tumor positive Acute Lymphoblastic Leukemia. K. Schaefer-Rego, Z. Cells. R. Timothy Mulcahy, Alain Carminati, Jean-Louis Arlin, L. G. Shapiro, J. G. Mears, and D. Leibowitz. Barascut. and Jean-Louis Imbach. * 870 Glucose Metabolism in Drug-sensitive and Drug-resistant Human Breast Cancer Cells Monitored by Magnetic Resonance Spectros- *N02 Effects of Steroid Hormones and Peptide Growth Factors on copy. Robbe C. Lyon, Jack S. Cohen, Patrick J. Faustino, Protooncogene c-fos Expression in Human Breast Cancer Cells. Frederique Megnin, and Charles E. Myers. George Wilding, Marc E. Lippman, and Edward P. Gelmann. * 878 Lymphokine-activatedKiller Cells in Rats: Analysis of Tissue and * 806 Kinetic Analysis of ChoriocarcinomaCell Intoxication Inducedby Strain Distribution, Ontogeny, and Target Specificity. Nikola L. Ricin and Ricin A Chain Immunotoxin. Karnn Braham. Simone Vujanovic, Ronald B. Herberman, and John C. Hiserodt. Junqua, Thomas Tursz, Jean-Bernard Le Pecq, and Marc 884 Lymphokine-activatedKiller Cells in Rats: Analysis of Progenitor Lipinski. and Effector Cell Phenotype and Relationship to Natural Killer Contrasting Actions of Tamoxifen on Endometrial and Breast Cells. Nikola L. Vujanovic, Ronald B. Herberman, Michael W. Tumor Growth in the Athymic Mouse. Marco M. Gottardis, Olszowy, Donald V. Cramer, Raoul R. Salup, CraigW. Reynolds, Simon P. Robinson, Pondichery G. Satyaswaroop, and V. Craig and John C. Hiserodt. Jordan. $891 Distinction of Partially Purified Human Natural Killer Cytotoxic * 816 Monoclonal Antibody to Human Carcinoma-associated Protein Factor from Recombinant Human Tumor Necrosis Factor and Recombinant Human Lymphotoxin. Tammo Bialas, Jonathan Complex: Quantitäten in Normal and Tumor Tissue. Rita Kolitz, Ester Levi, Andrej Polivka, Sadik Oez, Glenn Miller, and Falcioni, Ada Succhi. James Resau, and Stephen J. Kennel. Karl Weite. *822 Role of Oxygen Radicals in 12-0-Tetradecanoylphorbol-13-ace- 899 Bromine-80m-labeled Estrogens: Auger Electron-emitting, Estro tate-induced Squamous Differentiation of Cultured Normal Hu gen Receptor-directed Ligands with Potential for Therapy of man Bronchial Epithelial Cells. Edward W. Gabrielson, Gerald Estrogen Receptor-positive Cancers. Eugene R. DeSombre, M. Rosen, Roland C. Grafstrom, Karyn E. Strauss, Masao Ronnie C. Mease, Alun Hughes, Paul V. Harper, Onofre T. Miyashita, and Curtis C. Harris. DeJesus, and Arnold M. Friedman. t The CONTENTS arranged by Subject Category can be found immediately following these CONTENTS. Downloaded from cancerres.aacrjournals.org on October 2, 2021. © 1988 American Association for Cancer Research. 907 L-Arabinose Resistance Test with Salmonella typhimurium as a *993 Human Papillomavirus Types and Localization in Adenocarci Primary Tool for Carcinogen Screening. Gabriel Dorado and noma and Adenosquamous Carcinoma of the Uterine Cervix: A Carmen Pueyo. Study by in Situ DNA Hybridization. Toni Tase, Takashi Okagaki, Barbara A. Clark, Dawn A. Manias, Ronald S. Ostrow, 913 Purification and Characterization of a Bindable Form of Mito Leo B. Twiggs, and Anthony J. Paras. chondria! Bound Hexokinase from the Highly Glycolytic AS-30D Rat Hepatoma Cell Line. Richard A. Nakashima, Marco G. Paggi, 999 Irradiation-inducedMarkerChromosomes in a Metastasi/log Mu Laura J. Scott, and Peter L. Pedersen. rine Tumor. Lydia E. McMorrow, Sandra R. Wolman, Sandra Bornstein, and James E. Talmadge. * 920 Characterization of the in Vitro and in Vivo Species Preference of Human and Murine Tumor Necrosis Factor-a. Susan Mukavitz CLINICAL AND EPIDEMIOLOGICAL Kramer, Bharat B. Aggarwal, Thomas E. Eessalu, Susan M. INVESTIGATIONS McCabe, Bobbe L. Ferraiolo, Irene S. Figari, and Michael A. Palladino, Jr. The Epidemiológica! section contains further articles pre *<>26 Immunochemotherapy of a Murine Thymoma with the Use of sented at the Fifth Symposium on Epidemiology and Cancer IdarubicinMonoclonal AntibodyConjugates. Geoffrey A. Pietersz, Registries in the Pacific Basin, November 16-21,1986, Kauai, Mark J. Smyth, and Ian F. C. McKenzie. Hawaii. * 932 Binding of Castrili,- to Human Gastric Carcinoma Cell Lines. 1004 Case-Control Study of Gestational Choriocarcinoma.Jonathan D. Janet Weinstock and Graham S. Baldwin. Buckley, Brian E. Henderson, C. Paul Morrow, Charles B. *93H Synergistic Cell Inactivation of Human NHIK 3025 Cells by Hammond, Ernest I. Kohorn, and Donald F. Austin. Cinnamaldehyde in Combination with cis-Diamminedichloro- platinum(II). John M. Domish, Erik O. Pettersen, and Reidar 1011 Oral Contraceptives and Cervical Carcinoma in Situ in Chile. Oftebro. Ramiro Molina, David B. Thomas, Alfredo Dabancens, Jorge Lopez, Roberta M. Ray, Luis Martinez, and Oriana Salas. 943 Suppressor Lymphokine Produced by Rat I-Cells in Response to Syngeneic Mammary Adenocarcinoma 13762A. Neil D. 1016 Dysplastic Nevi in Association with Multiple Primary Melanoma. Christensen, John W. Kreider, and Rick L. Horetsky. Linda Titus-EmstofT, Paul H. Duray, Marc S. Ernstoff, Raymond L. Barnhill. Pamela L. Horn, and John M. Kirkwood. * 950 Detection of a Low Frequency of Activated ras Genes in Human Melanomas Using a Tumorigenicity Assay. FrançoiseRaybaud, 1019 Level of HLA Antigens in Locoregional MétastasesandClinical Tetsuro Noguchi, Irene Maries, JoséAdelaide, Jacqueline Course of the Disease in Patients with Melanoma. Sjoerd G. van Planche, MichèleBatoz, Christian Aubert, Odile de Lapeyriere, Duinen, Dirk J. Ruiter, Eva B. Broecker, Edo A. van der Velde, and Daniel Birnbaum. Clemens Sorg, Kees Welvaart, and Soldano Ferrone. 954 Transplantation Studies of a Putative Lymphosarcoma of Xeno- 1026 Endocrine Status of Premenopausal Node-positive Breast Cancer pus. Maryam Asfari and Charles H. Thiébaud. Patients following Adjuvant Chemotherapy and Long-Term Ta- 958 Mycobacterium-induced Infectious Granuloma in Xenopus: His- moxifen. Peter M. Ravdin, Nancy F. Fritz, Douglass C. Tormey, and V. Craig Jordan. topathology and Transmissibility. Maryam Asfari. *964 Biphasic Effects of 12-0-Tetradecanoylphorbol-13-acetate on the 1030 Expression of Ila-ras Oncogene Products in Human Neuroblas- tomas and the Significant Correlation with a Patient's Prognosis. Cell Morphology of Low Calcium-grown Human Epidermal Car cinoma Cells: Involvement of Translocation and Down Regulation Takeo Tanaka, Dennis J. Slamon, Hiroko Shimoda, Chiaki Waki, of Protein Kinase C. Yasuo KJtajima, Shunichiro Inoue, Seiji Yoshinori Kawaguchi, Yoshito Tanaka, and Noriaki Ida. Nagao, Ko-ichi Nagata, Hideo Yaoita, and Yoshinori Nozawa. 1035 Discordant Maturation as the Primary Biological Defect in 971 Histochemical Analysis