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Georgia Public Health Laboratory Service Manual Director’S Letter

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Georgia Public Health Laboratory Service Manual Director’S Letter GGEEOORRGGIIAA PPUUBBLLIICC HHEEAALLTTHH LLAABBOORRAATTOORRYY SSEERRVVIICCEE MMAANNUUAALL 22001133 1 GEORGIA PUBLIC HEALTH LABORATORY SERVICE MANUAL DIRECTOR’S LETTER .......................................................................................................................... 4 ORGANIZATIONAL CHART ................................................................................................................. 5 GEORGIA PUBLIC HEALTH LABORATORY DIRECTORY ............................................................... 6 DIAGNOSTICS LABORATORY SERVICES ........................................................................................ 7 MICROBIOLOGY SERVICES ......................................................................................................... 7 BACTERIOLOGY ............................................................................................................... 8 BORDETELLA PERTUSSIS ............................................................................................................. 8 CHLAMYDIA & GONORRHEA NUCLEIC ACID AMPLIFICATION TEST ...................................... 12 ENTERIC BACTERIOLOGY ........................................................................................................... 17 FOODBORNE OUTBREAKS .......................................................................................................... 21 GONORRHOEA CULTURE ............................................................................................................ 28 THROAT CULTURE FOR GROUP A STREPTOCOCCUS ............................................................ 31 SPECIAL BACTERIOLOGY ............................................................................................................ 33 IMMUNOLOGY ................................................................................................................. 37 INFECTIOUS DISEASE SEROLOGY ............................................................................................. 37 HCV VIRAL LOAD TESTING .......................................................................................................... 40 MYCOBACTERIOLOGY .................................................................................................. 46 ISOLATION AND IDENTIFICATION OF MYCOBACTERIA ........................................................... 46 PARASITOLOGY ............................................................................................................. 50 INTESTINAL PARASITES ............................................................................................................... 50 BLOOD AND TISSUE PARASITES ................................................................................................ 54 MISCELLANEOUS SPECIMENS .................................................................................................... 57 TELE-DIAGNOSIS .......................................................................................................................... 60 VIROLOGY ....................................................................................................................... 61 HUMAN IMMUNODEFICIENCY VIRUS ASSAYS .......................................................................... 61 HIV-1 VIRAL LOAD TESTING ......................................................................................................... 65 RABIES ........................................................................................................................................... 68 VIRUS ISOLATION AND IDENTIFICATION ................................................................................... 71 EMERGENCY PREPAREDNESS ................................................................................................. 74 CHEMICAL THREAT........................................................................................................ 76 RAPID TOXIC SCREEN (RTS) ....................................................................................................... 77 CYANIDE IN WHOLE BLOOD ........................................................................................................ 77 VOLATILE ORGANIC COMPOUNDS (VOC) IN WHOLE BLOOD ................................................. 79 TETRAMINE IN URINE ................................................................................................................... 81 ORGANOPHOSPHATE NERVE AGENT METABOLITES (OPNA) IN URINE ............................... 83 METABOLIC TOXINS IN URINE ..................................................................................................... 85 ABRINE AND RICININE (ABRC) IN URINE .................................................................................... 87 MERCURY, LEAD, AND CADMIUM IN WHOLE BLOOD ............................................................... 89 TOXIC ELEMENTS SCREEN (TES) IN URINE .............................................................................. 91 MERCURY IN URINE ...................................................................................................................... 93 MOLECULAR BIOLOGY/BIOTERRORISM .................................................................... 95 BIOLOGICAL THREAT AGENT ...................................................................................................... 96 REFERENCE TESTING .................................................................................................................. 96 BORDETELLA PERTUSSIS, B. PARAPERTUSSIS, AND B. HOLMESII ....................................... 97 BY REAL-TIME PCR ....................................................................................................................... 97 INFLUENZA A AND B SCREENING PANEL BY rRT-PCR ............................................................ 99 INFLUENZA A VIRUS CHARACETERIZATION PANEL BY rRT-PCR ......................................... 101 MUMPS VIRUS BY rRT-PCR ........................................................................................................ 103 NOROVIRUS GI AND GII BY rRT-PCR ........................................................................................ 104 POX VIRUSES BY REALTIME-PCR ............................................................................................. 105 VARICELLA-ZOSTER VIRUS BY REAL TIME-PCR .................................................................... 110 MEASLES VIRUS BY REAL TIME-PCR ....................................................................................... 111 2 CHEMISTRY/HEMATOLOGY ..................................................................................................... 113 NEWBORN SCREENING SERVICES ........................................................................... 113 SCIENTIFIC SERVICES ................................................................................................. 119 WAYCROSS PUBLIC HEALTH LABORATORY ....................................................................... 120 CHLAMYDIA & GONORRHEA NUCLEIC ACID AMPLIFICATION TEST .................................... 121 BLOOD LEAD TESTING ............................................................................................................... 126 INTESTINAL PARASITES ............................................................................................................. 129 PINWORMS .................................................................................................................................. 131 RABIES ......................................................................................................................................... 133 SYPHILIS ...................................................................................................................................... 136 WATER TESTING PROGRAM ..................................................................................................... 139 LABORATORY OPERATIONS ................................................................................................... 141 CENTRAL ACCESSIONING / DATA PROCESING (CA/DP)........................................ 142 REPORTS AND RECORDS UNIT ................................................................................. 143 LABORATORY SERVICES AND SUPPLY UNIT .......................................................... 144 SPECIMEN COLLECTION OUTFIT INFORMATION .................................................... 145 LABORATORY INFORMATION MANAGEMENT SYSTEM ...................................................... 148 BILLING UNIT ............................................................................................................................. 149 3 DIRECTOR’S LETTER July, 2013 Dear Georgia Public Health Laboratory Customer: We are pleased to provide you with the latest revision of the “Laboratory Service Manual” (LSM) for the Georgia Public Health Laboratory (GPHL). We have included material about changes to our service menu and in the way we provide services. For those of you who have Internet access, the LSM is available on the Department of Public Health Web Site at www.health.state.ga.us/programs/lab/index.asp. At this website you will also find the new consolidated GPHL Submission Form (#3583) for submitting all specimens other than Newborn Screening, as well as Fee and FAQ lists. If you have any questions or concerns regarding the services provided by the Georgia Public Health Laboratory, please do not hesitate to contact me at 404/327-7900 or to call one of the
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