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9-10-2009 Washington University Record, September 10, 2009

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Recommended Citation "Washington University Record, September 10, 2009" (2009). Washington University Record. Book 1186. http://digitalcommons.wustl.edu/record/1186

This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Medical News: Preschoolers 'Chance Aesthetics': Major Washington People: Fagan do not outgrow depression Kemper exhibit opens Sept. 18 *# a leader in Alzheimer's research 1

H Washington University in Stlouis Sept. 10, 2009 record.wustl.edu University steps up preparations for H1N1 Visit wustl.edu/flu for latest information about the illness

As students, faculty and staff Glass also recommends that return to campus this fall faculty, staff and students able to from all corners of the world, be vaccinated for the typical sea- Washington University adminis- sonal flu receive flu shots. While trators and health officials are those will not protect a person* monitoring the spread of the against the H1N1 virus, they will H1N1 (swine flu) virus and ensur- help prevent the spread of the ing the University is prepared seasonal flu and "false alarms" for should an outbreak occur on H1N1. campus. Those feeling flu-like symptoms WUSTL's Emerging Infectious are encouraged to contact their Disease Task Force — a team of primary health provider and to University administrators and stay home. Flu symptoms include: School of Medicine faculty formed • Fever last spring — meets regularly to • Cough refine the University's pandemic • Sore throat flu preparations and to keep the • Headaches GOOd etiquette goes a long Way Jacqueline Ong (left) and McDonnell International Scholars University community updated • Muscle aches. Academy member Juanyi Yu (right) listen as Scott Mclntosh, events specialist in the Career Center, with the latest information about In addition to information on explains the nuances of dining etiquette during a luncheon for the McDonnell scholars Sept. 1 in the illness. wustl.edu/flu, any significant Whittemore House.Topics covered included silverware placement, table manners and American The University has launched a changes in recommendations will vs. continental styles of eating. McDonnell scholars are international students selected on the new Web site, wustl.edu/flu, to be shared with students, parents, basis of their promise to become future leaders in academia, government, the professions or the keep the community updated and faculty, staff and others in the corporate world. The Academy provides academic, cultural and social opportunities to help the relay the latest information. community through appropriate scholars develop into future leaders knowledgeable about the United States and critical interna- "The task force, along with the ■ emergency communication chan- tional issues. Yu is a scholar at the School of Engineering & Applied Science; Ong is married to University's Crisis Management nels such as WUSTL Alerts, the Kek (Michael) Ong, a scholar at the George Warren Brown School of Social Work. Team, chaired by Steve Hoffner, University's emergency notification assistant vice chancellor for opera- system; the emergency Web site, tions, has developed a comprehen- emergency.wustl.edu; and the sive emergency management plan emergency hotline, 935-9000 or Pairing cochlear implant, hearing aid and regularly practices responding toll-free 888-234-2863. to emergencies such as pandemic Additional information about a benefits adults with hearing loss flu," said task force chair Alan serious emergency also is available Glass, M.D, assistant vice chancel- from campus media (WUTV BY GWEN ERICSON sound they heard when using both adults lose their hearing as they lor and director of the Habif Health Channel 22 and KWUR 90.3 FM) devices. age, and it may not be financially & Wellness Center. "This includes or KMOX (1120 AM), which is the Adults with severe hearing loss "It is increasingly common to or physically possible for them to assuring that health-care providers regional radio station identified for benefit from pairing a cochlear place cochlear implants in both ears undergo surgery for two cochlear have adequate supplies, informa- emergencies. implant in one ear with a hearing when patients implants. So it is important to tion and protocols and that com- WUSTL's Student Health aid in the other ear, even though have profound know if there is a benefit to using a munications are regularly updated." Services is prepared to provide the sound signals from each de- hearing loss on hearing aid plus a single cochlear Glass said faculty, students and special assistance and counseling vice are very different, according both sides, but implant." staff can reduce the risk of spread- to returning students with flu to a School of Medicine study the majority of Each of the 19 study partici- ing illnesses by covering their concerns. For more information, published in the Journal of the these bilateral pants received a cochlear implant coughs, using tissues and washing visit shs.wustl.edu. American Academy of Audiology. implants are in one ear and a hearing aid for the their hands frequently. The Centers for Disease Control The patients were better able to done in chil- other ear from WUSTL surgeons To guard against a flu outbreak and Prevention and other govern- hear spoken words and to locate dren," said lead at Barnes-Jewish Hospital. The at WUSTL, more than 700 hand ment Web sites also contain useful the direction of a sound with both author Lisa participants were seen at the Adult sanitizer stations are being in- information on influenza. Visit devices turned on compared with Potts Potts, Ph.D., Cochlear Implant and Aural stalled in high-traffic areas of the cdc.gov/h 1 n 1 flu/index.htm; either device alone. Additionally, research in- Rehabilitation Division at the Danforth, North, West and pandemicflu.gov; or hhs.gov. the patients liked the fuller, richer structor in otolaryngology. "Many See Implant, Page 6 Medical campuses. See Preparation, Page 6 United Way Campaign Under Way: Needs greater than ever; Wrighton says

BY JESSICA DAUES breakfast at Whittemore House. The University's goal is to Stephen raise $600,000 for the United Way. P. Zwolak, Even $1.50 — the price of a large soda — can make a The United Way of Greater St. Louis provides more executive difference in a little girl's life, said Stephen P. Zwolak, than $1 million in support each week to nearly 200 local director of executive director of the University City Children's agencies that offer an array of services, including job the Univer- Center (UCCC). counseling and training, affordable child care, disaster sity City The UCCC, with support from the United Way of relief, opportunities for exercise and recreation, and Children's Greater St. Louis, provides care for nearly 200 young much more. Center, children, Zwolak said. That includes kids from families "If you have been following the events of the last year, discusses like Tamika's, whose mother had to scrounge for coins in you know we've faced some challenging times," Wrighton the impact her car cushions to pay Tamika's reduced $20-per-week said. "While we face constraints, those in our community of United Way contri- tuition. are facing even greater constraints than we have. The butions And then there are middle-class families like needs are greater than ever." on his Elizabeth's, Zwolak said. Facing a pay reduction at his The key to success in the 2009 campaign, Wrighton organization. engineering job, Elizabeth's father was unable to afford said, is increased participation in the WUSTL commu- the UCCC's full tuition. nity. Participation in past campaigns has hovered around In both cases, United Way pitched in to provide schol- 14 percent, and the University is looking to grow that arship assistance to each family. number in 2009. "Contributions to the United Way really do funnel to WUSTL offers employees two ways to contribute: via us," Zwolak said. "We see it on a monthly basis. pledge cards, which are being sent through campus mail, "It's remarkable what they do," he said. and online using the HRMS system. With the goal of supporting the UCCC and many More than 90 cents of each dollar the United Way other community organizations, Washington University's receives is given to a United Way agency to benefit the 2009 United Way campaign began Sept. 2 with a kickoff See Campaign, Page 2 WASHINGTON UNIVERSITY MEDICAL LIBRARY

3 2201 20362 7589 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS

Wihl to be installed as the Lewin Distinguished Professor in the Humanities

BY SUSAN "His reputation as a scholar largest single gifts in Rice's history banking, venture capital and legal — "The Contingency of Theory, KlLLENBERG McGlNN and administrator is well-known, in the amount of $20 million for professions. Pragmatism, Expressivism, and and his interest in strengthening the recruitment of star faculty. Prior to joining Rice, Wihl was Deconstruction" and "Ruskin and Gary S. Wihl, Ph.D., who our academic departments and His principal accomplishments at Emory University, where he was the Rhetoric of Infallibility" — joined Washington University interdisciplinary programs is most included the establishment of a professor of English and acting and co-editor of two collections of July 1 as dean of the faculty of welcome. I am thrilled that Gary new doctoral program in art dean of the Graduate School of essays. Arts & Sciences, will be installed as and his wife, Sarah, have joined history in collaboration with Arts and Sciences for more than He has received numerous the Hortense and Tobias Lewin the Washington University com- Houston's major art museums; two years. awards and grants, including Distinguished Professor in the munity," Macias said. increasing support for faculty His many achievements at many from the Social Sciences Humanities during a 4:30 p.m. Sarah Westphal-Wihl, Ph.D., research by 348 percent; in- Emory included restructuring the and Humanities Research Council ceremony Wednesday, Sept. 16, joined the Department of Ger- creasing graduate stipends by graduate-school budget to phase of Canada. ■ announced Chancellor Mark manic Languages & Literatures in 32.5 percent; and adding postdoc- in fifth-year funding for doctoral The Hortense and Tobias S. Wrighton. Arts & Sciences as associate toral fellowships in the fields of students in the humanities and Lewin Distinguished Profes- The ceremony will be held in professor. gender studies, social sciences; organizing a major sorship in the Humanities was the Jerzewiak Family Auditorium Wihl, who will deliver a talk classics, lin- national conference on philan- established in 1987 by a gift from in the Arts & Sciences Laboratory titled "The Art of Education" at guistics and thropy and the research university; the late Tobias Lewin to honor his Sciences Building. his installation ceremony, said: German and sponsoring the establishment wife, Hortense, who died in 1983. Wihl, who also is a professor in "I'm delighted to have the oppor- studies. of a new Center for Humanistic The gift also reflects Tobias the Department of English in Arts tunity to address the University With the Inquiry. Lewin's interest in the humanities & Sciences, came to WUSTL from community as an educator and support of A native of Montreal, Canada, and his desire to create more Rice University, where he was dean scholar as well as in my role as the Andrew Wihl earned a bachelors degree in awareness of the importance of of its School of Humanities and the dean. It is an honor for me to hold Mellon Foun- 1976 and a master's degree in the humanities and a liberal-arts Francis Moody Newman Professor this titled professorship. I'm very dation, Wihl 1978, both in English, from McGill education. Tobias Lewin died in of the Humanities. grateful to the chancellor and developed an University. He earned a doctorate 2001. "Washington University is provost for this appointment, and Wihl innovative in English from Yale University in Wihl becomes the third holder fortunate to have Gary Wihl join I look forward to meeting Phyllis training pro- 1983. of the professorship. Lynne our academic leadership team," Goldberg, the Lewins' niece, at the gram for doctoral students in the Following two postdoctoral Tatlock, Ph.D., a professor of Wrighton said. "As an accom- ceremony on the 16th." humanities. He also launched new fellowships, he returned to McGill Germanic languages and litera- plished professor and experienced As dean of Rice University's undergraduate programs in cre- in 1985 as assistant professor of tures, also holds the Hortense and leader, Gary will guide Arts & School of Humanities, Wihl was ative writing, poverty and social English and was promoted to Tobias Lewin Distinguished Sciences during this important responsible for 12 departments, justice studies; a package of study- associate professor in 1989 and to Professorship in the Humanities, time in our history." three centers and four interde- abroad fellowships and courses; professor in 1996. and Naomi Lebowitz, Ph.D., is the "Gary Wihl brings a tremen- partmental programs; 150 tenure- and a pilot program in medical While at McGill, he served as Hortense and Tobias Lewin Dis- dous record of success to Arts track faculty and lecturers and humanities. associate dean of the Faculty of,. tinguished Professor Emerita in & Sciences," said Edward S. Macias, 50 administrative staff; and a Wihl built strong relationships Graduate Studies and Research the Humanities. Ph.D., provost, executive vice budget of approximately with alumni and the Houston from 1991-93 and from 1996-99 as The Lewins, both WUSTL chancellor for academic affairs and $26 million. community through the establish- chair of the Department of Eng- alumni, made many other signifi- the Barbara and David Thomas During his six-year tenure as ment of a Humanities Advisory lish, where he eliminated an oper- cant contributions to their alma Distinguished Professor in Arts dean, Wihl raised more than Board consisting of distinguished ating deficit, increased support for mater, including an endowed & Sciences. $40 million, including one of the alumni from the arts, investment graduate students, revitalized the professorship in the School of theater program, recruited new Medicine to further research in faculty and restructured the de- cardiovascular diseases. partmental curriculum. Douglas L. Mann, M.D., is the Wihl's research focuses on the Tobias and Hortense Lewin interpretation of liberalism and Professor and director of the constitutional change in selected Cardiovascular Division in the 19th- and 20th-century English Department of Medicine. and American authors. For more information about He is the author of two books the event, call Dhorotha Baldwin published by Yale University Press at 935-4785.

All-University blood drive Sept. 15

BY NEIL SCHOENHERR director of the Community Service Office and associate direc- The first of four University-wide tor of the Richard A. Gephardt blood drives this academic Institute for Public Service. year will be held Sept. 15 at nine The annual drives are quite locations throughout the Dan- effective. During the 2008-09 forth and Medical campuses. academic year, 1,845 productive All students, staff and faculty units of blood were donated, members are encouraged to par- compared with 609 in the 2006-07 ticipate in this effort to replenish academic year. the region's blood supply. To donate, sign up on online at Why donate blood? According communityservice.wustl.edu/bd. to the American Red Cross, each There you can also view a com- year more than 4.5 million Amer- plete schedule with times and ican lives are saved by blood locations and sign up to be a transfusions. Every two seconds, volunteer at the drive. someone in America needs blood. The drive is sponsored by the One in three people will need a Community Service Office in blood transfusion in their life- collaboration with the American Are algae the answer? Nearly 100 scientists from all over the world gathered at WUSTL's times, and there is no substitute Red Cross and Mississippi Valley Knight Center Sept. 1 and 2 to discuss whether algae might be part of the solution to the problem for human blood. Regional Blood Center. of global warming in a conference sponsored by the International Center for Advanced Renewable "One hour of your time as a Future blood drives are sched- Energy and Sustainability (l-CARES). Could algae provide a cheaper and more efficient way of blood donor can save up to three uled for Nov. 11; Jan. 26, 2010; capturing carbon dioxide than plants such as corn or switchgrass? In opening remarks, Sally lives," said Stephanie Kurtzman, and March 31, 2010. Benson, Ph.D. (left), director of the Global Climate and Energy Project at Stanford University, and l-CARES Director Himadri Pakrasi, Ph.D. (right), the George William and Irene Koechig Freiberg Professor of Biology in Arts & Sciences and professor of energy in the School of Engineering & Applied Science, challenged the attending scientists to run the numbers and sort fact from fiction. Chancellor Mark S. Wrighton (center) welcomed the scientists to WUSTL. Second

by Hugh Grant, president and Founded in 1905 • Washington University in St. Louis community news Campaign chief executive officer of Mon- santo Co. Volume 34, Number 5 Donations can be made The WUSTL campaign offi- online or via pledge cards cially ends in late October, but the Associate Vice Chancellor Steven J. Givens Record (USPS 600-430; ISSN 1043-0520), - Executive Editor Susan Klllenberg McGinn - from Page 1 Office of Human Resources will Published for the faculty, staff and friends accept pledge cards up until the Editor Leslie Gibson McCarthy of Washington University. Produced weekly end of the calendar year and Associate Editor Neil Schoenherr during the school year, except school community. United Way- community." beyond. Assistant Editor Jessica Daues holidays, and monthly during June, July supported agencies serve a large, A gift of $250 to the United Medical News Editor Beth Miller and August by the Office of Public Affairs, To make a pledge online, visit Calendar Coordinator Angela Hall diverse population of more than Washington University, Campus Box 1070, Way, for example, can provide hr.wustl.edu and use your WUSTL Print Production Carl Jacobs One Brookings Drive, St. Louis, M0 63130. one million people each year after-school care for one child in KEY to sign into HRMS Self Online Production Tammy Ritterskamp Periodicals postage paid at St. Louis, M0. — approximately one of every need for six weeks, or four days in Service. Click on Employee Self News & Comments Where to send address changes three in the St. Louis area. a shelter with meals and counsel- Service and select United Way (314) 935-5293 Postmaster and nonemployees: Record, "I share a conviction with ing for an individual suffering Campus Box 1070 Pledges. For assistance with pass- Washington University, Campus Box 1070, [email protected] many that the United Way is one from alcohol or chemical words, call the Help Desk at One Brookings Drive, St. Louis, MO 63130. of the most effective organizations dependency. 935-5707. Medical News Employees: Office of Human Resources, that help people in our commu- A gift of $50 can provide swim For more information about (314)286-0119 Washington University, Campus Box 1184, nity," Wrighton said. "A great lessons for 10 children from the United Way of Greater St. Campus Box 8508 One Brookings Drive, St. Louis, M0 63130. fraction of the financial support low-income families, or a com- [email protected] Louis, visit stl.unitedway.org. The Reprint permission Calendar Submissions that goes to the United Way makes plete outfit and school supplies Web site also features a video Articles may be reprinted with appropriate Fax: (314) 935-4259 its way into the services that help for a child in need. about the United Way, and those credit to Washington University in St. Louis Campus Box 1070 the people in our community, WUSTL's drive coincides with who watch the video can enter to Record. [email protected] including a significant fraction of the United Way's own $66.5 mil- win gift cards, St. Louis Cardinals our own Washington University lion campaign, which is chaired tickets or a 2009 Ford Focus. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 10,2009 3 School of Medicine Update Children's craniofacial images featured in unique database

BY BETH MILLER physician who painstakingly mea- sured angles and distances be- School of Medicine pediatric tween points on the face and head plastic and reconstructive and listed measurements by gen- surgeons and students have der and age in a book titled launched a unique database of "Anthropometry of the Head and 3-D craniofacial images of more Face." than 1,200 children that will help "That data is great, but it's not researchers study the form and really reproducible," said Kane, growth of the head and face. associate professor of plastic and The database, called reconstructive surgery and direc- Craniobank (craniobank.wustl. tor of the Cleft Palate and edu), is the first free and search- Craniofacial Institute at St. Louis able online database of images of Children's Hospital. "That's the children from infants to age 18 of beauty of Craniobank — it's there various ethnic backgrounds with- digitally. If someone wants to use out craniofacial disorders. The this data for a purpose that we images will be available to re- can't anticipate, they can down- searchers in a variety of fields, load it and use it for any math- including anthropology, psychia- ematical or analytical technique try, plastic and reconstructive they desire and apply it to that surgery, neurology and dentistry, data." to lead to earlier diagnoses and a Lipira visited several area Summer's bOUIlty (From left) Darlene Stewart and Wendy Zhang, both senior research techni- better understanding of craniofa- pediatricians' offices to acquire cians in the Department of Internal Medicine, choose fresh peaches from Baalman's Produce at cial conditions. images of children, with parental the farmer's market at the School of Medicine. The farmer's markets are the brainchild of the Spearheading the endeavor was permission, using a sophisticated School of Medicine's Wellness Council as a way to offer Medical Center employees and visitors access to a balanced assortment of fresh fruits and vegetables. The last market of the season will Angelo Lipira, now a 3-D camera system called be held from 11:30 a.m-4:30 p.m Thursday, Sept. 10, in the Fountain Plaza outside of the Barnes fourth-year medical digital stereophotogram- & Noble bookstore. student. Lipira devel- metry. The system uses oped the database dur- 12 cameras to take simple ing a yearlong Doris photographs of the head Duke Clinical Research from four different angles Fellowship with Alex and takes less than one Dorn named Needleman Professor A. Kane, M.D., the second. The photos are BY GWEN ERICSON University in January 2008 as Philadelphia College of Pharmacy Dr. Joseph B. Kim- then calibrated using associate chairman for transla- and Science. He earned a doctor- brough Chair for software to reconstruct a Gerald W. Dorn II, M.D., has tional research and director of the ate in pharmacology at the Uni- Pediatric Dentistry and Lipira high-resolution image. been named the Philip and Center for Pharmacogenomics at versity of Maryland School of a craniofacial surgeon at The stereophotogram- Sima K. Needleman Professor of the School of Medicine. Medicine. Needleman spent St. Louis Children's Hospital, and metry equipment is used daily in Medicine. "It is a privilege to be named 25 years at the School of Medicine, an information technology team the Cleft Palate and Craniofacial The professorship was estab- the inaugural recipient of this where he became a full professor from the Department of Surgery. Institute at St. Louis Children's lished to support a faculty mem- professorship," Dorn said. and chaired the school's Depart- Craniobank allows researchers Hospital to acquire images of all ber holding a key leadership posi- "Dr. Needleman is an exemplar ment of Pharmacology from 1976- to perform searches by age, gen- patients before and after surgery tion within the BioMed 21 initia- of the academic translational sci- 1989. He then became an execu- der, ethnicity, facial expression and to evaluate their growth over tive, a multidisciplinary impera- entist, having tive in the pharmaceutical indus- and hand preference to assemble a time. tive to rapidly convert research made impor- try. In 2004, Needleman was asso- group of healthy subjects for Researchers must register to findings into effective, individual- tant fundamen- ciate dean at the medical school studies. access the data and then provide ized treatments. tal scientific and assisted with the BioMed 21 "Our goal is for other investi- approval from their institution's Chancellor Mark S. Wrighton discoveries that initiative. gators to be able to download Institutional Review Board or and Larry J. Shapiro, M.D., execu- were success- Needleman is a leading expert large sets of data to be used in equivalent to use it. Nonregistered tive vice chancellor for medical fully developed on inflammation and the devel- studies of craniofacial form and users can access the database but affairs and dean of the School of into human oper of Celebrex, a widely used structure," Lipira said. "This will not see images of the children. Medicine, made the announce- therapies and arthritis drug. He serves on the would include studies of patho- Kane credits Lipira for his ment. defining novel WUSTL Board of Trustees. logical conditions where our determination in getting the proj- "The generosity of Dr. and pharmacologi- Sima Needleman earned a normative data could serve as ect done. Mrs. Needleman in establishing Dorn cal concepts bachelor's degree in elementary controls or studies of normal "He was incredibly dynamic in this professorship is greatly appre- that have education from Glassboro State craniofacial growth and trying to get what he needed to get ciated," Wrighton said. "Their gift broadly impacted our understand- College and a master's degree in development." in a small window of time given recognizes the importance of the ing of pharmacokinetics. The social work from the George War- Although Kane and his col- the scope of the project," Kane BioMed 21 initiative as a model unparalleled excellence of ren Brown School of Social Work. leagues have built an internal said. "I have to give all the credit for research and discovery that Washington University in the area She was a medical social worker in archive of patients they treat for a to Angelo, who really took it and leads quickly to new medical of human genomics provides a the Division of Obstetrics and variety of disorders of the head ran in a way that I couldn't have treatments, and we are grateful for unique opportunity for our institu- Gynecology at Jewish Hospital and face, such as birth defects, anticipated." their vision." tion to break new ground in the from 1976-1992 and then went injuries and burns, there was no The researchers also plan to "Gerald Dorn conducts re- rapidly evolving area of personal- into private practice until 1998. existing online database of so- acquire more images of children search in cardiac disease that is ized medicine directed by indi- Sima Needleman served 10 called normal head and face from underrepresented ethnic multidisciplinary in nature, and vidual genetic testing." years on the Brown School alumni shapes for comparison. groups. In the future, Kane would he is on the leading edge in the Philip Needleman, Ph.D., board, for which she chaired nu- Before Craniobank, the "bible" like to add DNA information with development of individualized earned bachelors and master's merous committees and served as of normative data was developed each image to allow for genetic care for heart disease," Shapiro degrees in pharmacology from the president from 1993-95. by Leslie Farkas, M.D., a Canadian studies. said. "His work epitomizes the ideals of 21st-century medicine in which basic science discoveries reshape and vastly improve health Depression in preschoolers is chronic and recurrent care on a personal level." Dorn's heart-failure research BY JIM DRYDEN said. "And it's not a nonspecific precursor of "Many disorders, and mental disorders in examines how the heart adapts to some later problem. It appears to remain true particular, are more treatable when the brain is increased stress and how these Child psychiatry researchers have found that to form — or to manifest a more changeable and neuroplastic," she said. adaptive mechanisms ultimately preschoolers don't outgrow depression, and phenomenon called homo- "We're hopeful that by identifying depression fail. His research into the factors depression in a 3-year-old doesn't turn into typic continuity — in that early, we may have more success treating it." that affect heart function integrates something different by the time that child is 5. it continues to be depres- But the new study, reported in the August the findings of human genetics Following more than 200 preschoolers for sion across time." issue of the Archives of General Psychiatry, did studies with experiments per- two years, a team led by Joan L. Luby, M.D., Preschoolers with de- not address how to treat depression in formed in genetically manipulated professor of child psychiatry, found that pre- pression are sad, have low preschoolers. mouse and fly models and basic schoolers diagnosed with depression at their energy and suffer with "The study makes absolutely no statements laboratory investigations using cell initial examination were four times more likely anhedonia, the inability to about treatment," Luby said. and molecular biology approaches. to have depression 12 or 24 months later than enjoy life. Luby said their "We definitely do not recommend treat- A cardiologist at Barnes-Jewish those who were not depressed when the study symptoms appear as age- ment with antidepressants because there is no Hospital and a top researcher in began. Luby adjusted versions of the evidence that they are either safe or effective in the area of pharmacogenomics A total of 75 preschoolers were diagnosed symptoms seen in older very young children. Instead, we currently are — how an individual's genetic with depression at the start of the study. Those children and adults. investigating a dyadic play therapy involving makeup influences the effect of kids were examined at six-month intervals for And like older children and adults, pre- children and their caregivers to learn whether drug therapy — Dorn has made the remainder of the study period. At the schoolers with depression tend to have chronic the emotional support such therapy delivers important contributions to the six-month follow-up, 64 percent were still and recurring problems with the disorder. might improve symptoms of depression in understanding of how genetic depressed, and 40 percent were depressed at Luby, director of WUSTL's Early Emotional preschoolers," Luby said. variations determine different 24 months. Development Program, said the good news is Luby said early results of the investigational patients' responses to heart failure "When you're depressed as a preschooler, that identifying depression in very young play therapy look promising, but they await therapy. it's not just a transient, developmental blip children may make it possible to begin treat- findings from their ongoing study. Dorn joined Washington that's going to spontaneously go away," Luby ment earlier and perhaps change outcomes. For more information, visit eedp.wustl.edu. 4 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS University Events Tension between chance, choice theme of Kemper exhibit Dripping or flinging paint; forms of artistic expression as well many of the artistic practices flipping coins to compose as the bourgeois values and ideals represented. musical scores; letting the they were understood to repre- The type of indeterminacy progressive decay of organic sent. These categories also provide derived from games and arbitrary materials determine a composi- a basic framework through which systems of order — such as the tion — since the early 20th cen- individual movements — includ- simple toss of a coin, where one tury, avant-garde artists have ing Dada, Surrealism, Abstract of two outcomes is equally likely used these processes and many Expressionism, Nouveau — provided Cage, Kelly, Morellet others to explore the creative Realisme and Fluxus — can be and other artists with a means of possibilities of chance and its traversed, allowing viewers to undermining concerns of style attendant release of authorial compare and contrast the use of and personal expression, thus intent. chance-based processes across facilitating the liberating explora- This fall, the Mildred Lane diverse historical and cultural tion of unorthodox methodolo- Kemper Art Museum will present contexts. gies for making art. "Chance Aesthetics," a major loan • "Collage, Assemblage and the A fully illustrated color cata- exhibition investigating the use of Found Object" examines three log — distributed by the chance as a key compositional closely related practices employed University of Chicago Press — principle in modern art. The by artists as means of destabiliz- accompanies the exhibition. exhibit opens with a reception at ing accepted views of the world Essays by Malone, Susan Lax- 7 p.m. Sept. 18 and remains on through fragmentation and juxta- ton, Ph.D., and Janine Mileaf, view through Jan. 4, 2010. position while negating tradi- Ph.D., draw connections across Organized by Meredith tional criteria for judging a work media and disciplines while link- Malone, Ph.D., assistant curator of art, such as the direct trace of ing the genesis and meaning of for the Kemper Art Museum, the artist's hand. Works by more than 40 avant-garde artists, including Jean artistic production through "Chance Aesthetics" will feature Duchamp's "Hat Rack" and Tinguely's "Metamatic No. 9," will be on display at the Kemper Art chance to larger socio-cultural, more than 60 works by more than Arp's "Objects Arranged accord- Museum through Jan. 4,2010. historical and theoretical contexts. 40 avant-garde artists from ing to the Laws of Chance III: The catalog also features ex- Europe and the United States, Symmetrical Configuration" humorous production of painting procedures. Though parameters tended entries on all works in the including Jean Arp, George provide early touchstones, in- machines, which took aim at both typically were stipulated in ad- exhibition, focusing on the pro- Brecht, John Cage, Marcel forming a wide range of subse- postwar gestural abstraction's vance, results were left largely to cesses employed and the rhetoric Duchamp, Max Ernst, Ellsworth quent artworks. Particularly in heroic mark-making and the serendipity. used to describe and theorize Kelly, Alison Knowles, Francois the post-World War II era, assem- supposed liberations of automatic Duchamp's promotion of them. Morellet, Robert Morris, Robert blage, coupled with chance — as production. nonintention on the part of the Both the reception and exhibi- Motherwell, Jackson Pollock, evinced in works such as Daniel • The final section, "Games and artist and his notion of "canned tion are free and open to the Dieter Roth, Niki de Saint Phalle Spoerri's snare paintings and de Systems of Random Ordering," chance," which describes pro- public. and Yves Tanguy, among others. Saint Phalle's shooting paintings examines chance as generated cesses that depend on chance yet For more information, visit At the exhibition's heart is a — offered artists a compelling through the implementation of paradoxically attempt to fix or kemperartmuseum.wustl.edu or central paradox involving the means of social critique as well as randomizing systems and standardize it, aptly characterize call 935-4523. tension between chance and a strategy for pushing the trajec- choice. tory of artistic production toward While many artists have process, performance and ephem- championed the creative possi- eral events. bilities of the arbitrary and the • In his 1924 "Manifesto of Special events planned with 'Chance' accidental — both as an attack on Surrealism" Andre Breton defined reason and logic and as a coun- Surrealism as "psychic automa- In conjunction with "Chance Aesthetics," the determine her chess moves and those of her terpoint to officially sanctioned tism in its pure state." Appro- Mildred Lane Kemper Art Museum will host a opponent. aesthetic tastes — artistic subjec- priated first from physiology and series of lectures, discussions and special events. Following the match, Bradley Bailey, Ph.D., tivity is never entirely ceded. psychiatry, the term "automatism" At 5 p.m. Sept. 23, Meredith Malone, Ph.D., assistant professor of art history at Saint Louis The controlled and the arbi- was applied to various techniques assistant curator for the Kemper Art Museum, will University — and co-author, with Shahade, of trary variously interplayed of spontaneous writing, drawing moderate a faculty panel discussion exploring "Marcel Duchamp: The Art of Chess" — will host a throughout the 20th century, and painting. chance, randomness and probability as they relate gallery talk on Duchamp's work. stimulating new forms of creative Examples range from Andre to the disciplines of art, music, literature, architec- On Nov. 9, the Department of Art History & invention that challenged long- Masson's sand paintings and ture and anthropology. Archaeology in Arts & Sciences will co-sponsor a standing assumptions about what automatic drawings to Ernst's On Oct. 7, the Department of Music in Arts & talk by Yve-Alain Bois, Ph.D., the eminent critic might constitute a work of art otherworldly frottages (rubbings). Sciences will host a "Chance Aesthetics" concert, and specialist in 20th-century European and and the role of the artist as au- Intended to bypass the conscious which will include experimental works by John American art on faculty at the Institute for tonomous creator. mind, these Surrealist experi- Cage and other composers. Advanced Study in Princeton, N.J. "Chance Aesthetics" explores ments later were adapted by ab- On Oct. 14, the Chess Club and Scholastic On Nov. 18, Tricia Y. Paik, assistant curator of these ideas in three thematic stract expressionists such as Center of Saint Louis will co-sponsor "Playing with modern and contemporary art for the Saint Louis sections: "Collage, Assemblage Pollock, who explored chance Chance: Duchamp, Chess and Roulette." Art Museum, will discuss Ellsworth Kelly and and the Found Object"; "Automa- effects of gravity and momentum The event will include a live chess match with "Chance Aesthetics." tism"; and "Games and Systems of on falling paint. Jennifer Shahade, two-time U.S. Women's Chess On Dec. 2, the museum will host a poetry work- Random Ordering." But by the late 1950s, diverse Champion, who will combine the ultimate game of shop exploring how poets historically have inte- Each section addresses key responses arose in opposition to strategy with the ultimate game of chance by em- grated chance into their artistic practice, followed avant-garde strategies designed to the Surrealist legacy, including ploying a specially designed roulette wheel to Dec. 4 by an informal poetry reading. subvert or rework traditional Swiss sculptor Jean Tinguely's

G-Proteins • Solar System • The War Before Darwin

"University Events" lists a portion of the Farrell Learning & Teaching Center, Hearth Oleg Kisselev, assoc. prof, of ophthalmol- 11 a.m. Energy, Environmental and Activation." Kai W. Wucherpfennig, cancer activities taking place Sept. 10-23 at Gallery. 747-3284. ogy, biochemistry and molecular biology, Chemical Engineering Seminar. "Solar immunology & AIDS, Dana-Farber Cancer Washington University. Visit the Web for "My Right Self: Transgender Consider- Saint Louis U. Maternity Bldg., Rm. 725. Cells by Design. Harvesting Light Energy Inst., Harvard U. Farrell Learning & expanded calendars for the Danforth ations." Sept. 21-0ct. 9. Farrell Learning 362-3315. With Nanostructure Assemblies." Prashant Teaching Center, Connor Aud. 362-2763. Campus (news-info, wustl.edu/calendars) Kamat, prof, of chemical engineering, U. of & Teaching Center Atrium. zinterm@wusm. 4:15 p.m. Earth & Planetary Sciences 4 p.m. Siteman Cancer Center Breast and the School of Medicine (medschool. Notre Dame. Lopata Hall, Rm. 101. wustl.edu. Colloquium. "Stratigraphy, Depositional Prevention & Control Research Seminar wustl. edu/calendars. html). 935-5548. Environment and Natural Gas Production Series. "Priority for Prevention of Breast From Organic-Rich Black Shales." Noon. Cell Biology & Physiology Lecture. Cancer Must Focus on Childhood Langhorne Smith, curator, Reservoir "XBP1, MIST1 and RAB GTPases: How Adolescent Lifestyle." Graham A. Colditz, Characterization Group, New York State Transcription Factors Establish Membrane prof, of surgery. Farrell Learning & Museum. Earth & Planetary Sciences Bldg., Trafficking Machinery." Jason C. Mills, Teaching Center, Holden Aud. 454-8981. Exhibits Lectures Rm. 203. 935-5610. asst. prof, of pathology & immunology. McDonnell Medical Sciences Bldg., 5:30 p.m. Cardiac Bioelectricity & Rm. 426. 362-6950. Tuesday, Sept. 15 "Chance Aesthetics." Sept. 18-Jan. 4. Thursday, Sept. 10 Arrhythmia Center Seminar. "Determinants 2 p.m. Siteman Cancer Center Prevention Kemper Art Museum. 935-4523. Noon. Genetics Seminar. "Complex Traits, of Cardiac Remodeling and Myocardial & Control Group Special Seminar. Entropy and Heat." Barak Alon Cohen, Recovery." Douglas L. Mann, prof, "Metabolic City." Sept. 18-Jan. 4. Kemper Saturday, Sept. 12 "Building Life Tables for Mortality From assoc. prof, of genetics. McDonnell Medical medicine. (5 p.m. reception.) Whitaker Hall, Art Museum. 935-4523. 8 a.m.-12:30 p.m. Critical Care CME Non-Cancer Causes — Implications of Sciences Bldg., Rm. 823. 362-2139. Rm. 218. 935-7887. "Changing the Face of Medicine: Course. Annual St. Louis Critical Care Competing Risks on Cancer Prevention." Celebrating America's Women 3 p.m. Chemistry Lecture. Annual Joseph Update. "Advances in the Management Yun-Hsin Claire Wang, asst. prof, of health Physicians." Through Sept. 18. Bernard W. Kennedy Memorial Lectures. "Imaging Friday, Sept. 11 of the Critically III Patient." Cost: $85. policy & management, Columbia U. Farrell Addiction in the Human Brain." Joanna St. Louis Marriott West, 660 Maryville Learning & Teaching Center, Holden Aud. Becker Medical Library. 362-7080. 8 a.m. Kathryn M. Buder Center for S. Fowler, dir., Brookhaven National Centre Dr. To register: 362-6891. 454-8981. American Indian Studies Panel "Double Exposure: Al Parker's Illustrations, Laboratory. Lab Sciences Bldg., Rm. 300. Discussion. "Honoring Kathryn M. Buder's 3:30 p.m. Assembly Series. Julie Otsuka, From Model to Magazine." Through 935-6530. Sept. 30. Olin Library, Lvl. 1, Grand Vision: Listening to the Native Voice." Monday, Sept. 14 author. Co-sponsored by the Freshman (8 a.m. continental breakfast.) Brown Hall Staircase Lobby and Ginkgo Rm. 935-7741. 3 p.m. Siteman Cancer Center Basic Science Noon. Center for New Institutional Social Reading Program. Graham Chapel. Seminar Series. Richard Wilson, prof, of Lounge. R.S.V.P. required: 935-4510. 935-5285. Sciences Lecture. "Leading in Green." "Edward and Joshua Geltman: A genetics. Eric P. Newman Education Center, 9:15 a.m. Pediatric Grand Rounds. "State of Isaac Berzin, dir., Interdisciplinary 5 p.m. Freedom From Smoking Class. Photographic Journey." Through Sept. 20. Seminar B. 454-7029. the Department." Alan Schwartz, prof, of Center-Herzliya, Israel. Seigle Hall, Rm. "Decision Process." Center for Advanced 4 p.m. Institute of Medicine Regional pediatrics. Clopton Aud., 4950 Children's 170. To R.S.V.P: [email protected]. Medicine, Barnard Health and Cancer Info. Place. 454-6006. . Center. To register: 362-7844. Meeting. "Genomics and the Future of 3 p.m. Siteman Cancer Center Seminar. Green Your Office Medicine." Speakers include Timothy Ley, 11 a.m. Chemistry Lecture. Annual Joseph "The Genetic Basis of Human Neuro- prof, of medicine, and Jeffrey I. Gordon, W. Kennedy Memorial Lectures. "New blastoma." John M. Maris, chief, div. of dir., Center for Genome Sciences. Wednesday, Sept. 16 Radiotracers and Applications in Human oncology, The Children's Hospital of If you have a question about (Reception follows.) Eric P. Newman Noon. Mallinckrodt Institute of Radiology Neuroscience." Joanna S. Fowler, dir., Philadelphia. South Bldg., Rm. 3907, Philip Education Center. 286-0073. Lecture. Annual G. Leland Melson Visiting something being recyclable, Brookhaven National Laboratory. McMillen Needleman Library. 454-8981. Professorship and Lecture. "Novel Imaging e-mail [email protected]. 4 p.m. Vision Science Seminar Series. "Why Lab., Rm. 311. 935-6530. 4 p.m. Immunology Research Seminar Methods for Oncologic Treatment Do We Need Heterotrimeric G-Proteins?" Series. "The Earliest Events in T Cell Response Assessment and Monitoring record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 10,2009 5

PAD examines dance and ethnic identity Assembly Series in full swing:

BY LIAM OTTEN Music of Thelonious Monk." Pulinkala will be joined by Min Kim, assistant professor of Otsuka, Jackley to speak Around the world, dance is often quite dance at Kennesaw, to perform his recent literally the physical embodiment of "Magnetic Fields." Author will talk about her debut novel cultural identity and practice. Yet converse- The Slaughter Project — directed by ly, for individual dancers, the power of such Cecil Slaughter, senior lecturer in dance Julie Otsuka, author of "When the their thoughts, their lives and the corre- traditions can give rise to certain expecta- — will perform "OverDrive," an ensemble Emperor Was Divine," this year's spondence between the father and his tions and even stereotypes based on per- piece inspired by the acceleration and inter- Freshman Reading Program selection, family. ceived identity. action of traffic. Ting-Ting Chang, Ph.D., will present the Assembly Series/ In real life, Otsuka's mother, uncle and -At 8 p.m. Saturday, Sept. 12, the Dance the Andrew Mellon Postdoctoral Fellow in Neureuther Library Lecture at grandparents were interred in Program in the Performing Arts Depart- Dance, will present her Los Angeles-based 3:30 p.m., Tuesday, Sept. 15, in camps, but she says that her ment (PAD) in Arts & Sciences will explore company, Dream Dance Contemporary Graham Chapel. mother spoke little about the the role of ethnicity in contemporary dance Arts, which will perform "Flying Goddess" Otsuka's debut novel ex- experience. — its pros and cons — with "Dancing Who a traditional Chinese dance, as well as plores themes of identity, loss It was difficult to communicate I Am," a panel discussion and informal "Falling Petals," an original work by Chang. and injustice. It is the story of a with her grandmother, because as concert featuring faculty members as well Rounding out the discussion will be Alicia Japanese immigrant couple she aged she spoke more Japanese as leading critics and choreographers from Graf, a former principal dancer with Alvin and their American-born and less English. Few wanted to around the country. Ailey American Dance Company and children living in California at speak about what happened The event, which is free and open to the Dance Theatre of Harlem. the outbreak of World War II. during the war, so extensive re- public, will take place in Edison Theatre. "Dancing Who I Am" is sponsored by The story focuses on the char- Otsuka search was necessary for Otsuka "We have an impressive group of dance the PAD and the Center for the Study of acters' experiences following to create the experiences of the scholars and choreographers coming from Ethics and Human Values as part of the the 1941 attack on Pearl Harbor. family in the book. St. Louis and from both coasts," said Mary- semester-long series "Ethnic Profiling: A "When the Emperor Was Divine" Otsuka earned a bachelor's degree in Jean Cowell, Ph.D., associate professor and Challenge to Democracy." Additional sup- describes the father's arrest and imprison- art from Yale University in 1984 and a coordinator of the Dance Program, who port is provided by the Office of the Vice ment in New Mexico, his family's long rail master of fine arts degree in creative will moderate the discussion. "Almost ev- Chancellor for Students, the Office of journey to an internment camp in the writing from Columbia University in eryone on the panel will either perform Diversity Initiatives, the Center for the Utah desert, and the three years in which 1999. She resides in New York. themselves or present their choreography Humanities in Arts & Sciences and the they were imprisoned. Otsuka writes of —Kurt Mueller through their company. The evening will be Kathryn M. Buder Center for American as much a dance concert as it is a Indian Studies in the George Warren Brown discussion." / School of Social Work. Kiva founder to talk on entrepreneurship Guests will include Rulan Tangen, a As part of the Ethnic Profiling series, distinguished visiting scholar in the PAD Tangen also will host a screening of the Jessica Jackley understands the power Sept. 17 in Simon Hall's May Auditorium. this fall. Recently named one of the "Top 25 award-winning Native American short of the personal connection. She dis- The lecture also is the kickoff event for to Watch" by Dance Magazine, Tangen is film "Ancestor Eyes" for the Buder Center covered it while visiting East Africa to the Skandalaris Center's annual business director and choreographer of DANCING at 1 p.m. Sunday, Sept. 13. conduct impact evaluation surveys for plan competitions: the Olin Cup, and the EARTH — Indigenous Contemporary Written and directed by Kalani Queypo, Village Enterprise.Fund. At the same YouthBridge Social Entrepreneur and Dance Creations, whose work reflects both "Ancestor Eyes" stars Tangen as Willa, a time, her husband, Matt Innovation Competition. the rich cultural heritage and the contem- young Native woman who falls sick and Flannery, was in the field film- ri^-i- In March 2005, seven loans porary identity of native peoples. returns to home of her mother (Tantoo ing interviews with small busi- were posted on Kiva.org for a She will perform her solo "The Naming," Cardinal), where both must come to terms ness entrepreneurs. When they total of $3,500. Recipients in- which explores the coming together of sky with her illness. saw firsthand the life-changing cluded a goat herder, a fishmon- and earth to name the plants and animals. Over the past two years, the film has power of micro financing, they ger, a cattle farmer and a restau- Other guests will include writer and won prizes at close to a dozen film festivals devoted themselves to creating rateur. Six months later, every critic Elizabeth Zimmer, former dance across North America. Following the their own program. loan had been repaid. editor of The Village Voice; Thomas screening, Tangen will lead a discussion That program is Kiva, which Last November, Kiva reached DeFrantz, Ph.D., a professor of music and about the treatment of native peoples and grew from a small personal the $50 million mark in loans; in theater arts at Massachusetts Institute of themes in film. project to one of the world's Jackley December, another milestone Technology who specializes in African The screening is free and open to the largest micro finance facilita- was reached with a record American performance; and New Delhi- public and takes place in Brown Hall tors, connecting budding entrepreneurs $3,827,400 of loans facilitated in one born choreographer Ivan Pulinkala, direc- Lounge. For more information, call with millions of dollars in loans from month. tor of dance at Kennesaw State University. 935-4510. hundreds of thousands of lenders around Both talks are free and open to the DeFrantz will perform "Just a Gigolo," a tap For more information on "Dancing Who the globe. public. For more information, call 935- piece excerpted from his "Monk's Mood: A I Am," visit padarts.wustl.edu or call Jackley will deliver the Assembly 4620 or visit assemblyseries.wustl.edu. Performance Meditation on the Life and 935-5858. Series/Skandalaris Lecture at 5 p.m. —Barbara Rea

Japan." Leah DeVun, asst. prof, of history, College. WU/ASICS National Invitational. Angiogenesis." Dushyant Sahani, assoc. 7 p.m. Center for the Study of Ethics & Monday, Sept. 21 Athletic Complex. 935-4705. prof, of radiology, Harvard U. Scarpellino Human Values Constitution Day Panel Texas A&M U. (Reception follows.) Co- Aud., 510 S. Kingshighway Blvd. 362-2866. Discussion. "Did the Japanese American 4 p.m. Immunology Research Seminar sponsored by East Asian Studies. Busch 3 p.m. Volleyball vs. U. of Wis.-Whitewater. Internment Violate Constitutional Rights ... Series. "DNA Damage Responses in Hall, Rm. 18. 935-5450. WU/ASICS National Invitational. Athletic 4 p.m. Biochemistry & Molecular Biophysics and Why Do We Care?" Part of Ethnic Developing Lymphocytes." Barry Sleckman, Complex. 935-4705. Seminar. "Mechanisms of DNA Break Profiling: A Challenge to Democracy Series. prof, of pathology & immunology. Farrell Repair in Mycobacteria." Stewart Shuman, 7 p.m. Women's Soccer vs. Grinnell Sponsored by Gephardt Inst. for Public Learning & Teaching Center, Connor Aud. research prof, in molecular biology, College. Washington University Classic. Service, the Freshman Reading Program 362-2763. Sloan-Kettering Inst. McDonnell Medical Francis Field. 935-4705. and Political Science Student Association. Sciences Bldg., Rm. 264. 362-4152. 7:30 p.m. Saint Louis Astronomical Society Music Danforth University Center, Rm. 242. Meeting. "The Formation of the Solar 7 p.m. Biology Dept. Webcast. "The War 935-9358. System." Angela Speck, asst. prof, of Sunday, Sept. 13 Before Darwin." Part of the Darwin 150 physics, U. of Mo. McDonnell Hall, Thursday, Sept. 17 Noon. Men's Soccer vs. Rhodes College. Project Lecture Series. Everett Mendelsohn, Friday, Sept. 18 Rm. 162. 935-4614. 8 p.m. Jazz at Holmes. Fresh Heir. Ridgley Francis Field. 935-4705. research prof, of the history of science, Hall, Holmes Lounge. 862-0274. Harvard U. Rebstock Hall, Rm. 322. 9:15 a.m. Pediatric Grand Rounds. "Yes We 935-6871. Can! Positive Youth Development — A Tuesday, Sept. 22 Wednesday, Sept. 16 Strategy for Intervention." Katie Plax, asst. Noon. Molecular Microbiology and 7 p.m. Men's Soccer vs. Westminster Thursday, Sept. 17 prof, of pediatrics. Clopton Aud., 4950 Microbial Pathogenesis Seminar Series. College. Francis Field. 935-4705. Children's Place. 454-6006. "Listeria Monocytogenes Crossing of Host Noon. Genetics Seminar. "Good at Being 11 a.m. Computer Science & Engineering Barriers." Marc Lecuit, prof, of infectious Sports Bad: Why Low-Affinity Binding Sites are Friday, Sept. 18 Colloquium. "Neurobotics and Walking diseases, Pasteur Inst. Cori Aud., 4565 Optimal for Responding to the Hedgehog Machines." M. Anthony Lewis, assoc. prof, McKinleyAve. 747-1329. All day. Men's Tennis. WU Fall Invitational. Morphogen." Scott Barolo, cell & Friday, Sept. 11 of electrical & computer engineering, II. of (Also all day Sept. 19-20.) Tao Tennis developmental biology, U. of Mich. Medical 5 p.m. Freedom From Smoking Class. Ariz. Cupples II Hall^Rm. 217.935-6160. 1:30 p.m. Women's Soccer vs. Brandeis U. Courts. 935-4705. School. McDonnell Medical Sciences Bldg., "Studying Your Habit and Building Francis Field. 935-4705. Rm. 823. 362-2139. 11 a.m. Energy, Environmental & Chemical Motivation." Center for Advanced Medicine, All day. Women's Tennis. WU Invitational. Engineering Seminar Series. "Nanoscale Barnard Health and Cancer Info. Center. 5:30 p.m. Volleyball vs. Pacific Lutheran U. (Also all day Sept. 19-20.) Tao Tennis Noon. Siteman Cancer Center Special Organic Hybrid Materials (NOHMs)." To register: 362-7844. WU/ASICS National Invitational. Athletic Courts. 935-4705. Seminar. "A Decade of Preclinical Lynden Archer, prof, of chemical & Complex. 935-4705. Chemopreventive Studies With NSAIDS and 2 p.m. Men's Soccer vs. Birmingham biomolecular engineering, Cornell U. Lopata C0X-2 Inhibitors: What Have We Learned? Wednesday, Sept. 23 7 p.m. Women's Soccer vs. Claremont- Southern College. Francis Field. 935-4705. Hall, Rm. 101.935-5548. What Might We Learn?" Ronald A. Lubet, Mudd-Scripps. Washington University 1 p.m. Institute for Public Health Annual Classic. Francis Field. 935-4705. 7:30 p.m. Volleyball vs. Juniata College. program dir„ National Inst. of Health. Farrell Noon. Cell Biology & Physiology Lecture. Conference 2009. "Multidisciplinary Annual Teri Clemens Invitational. Athletic Learning & Teaching Center, Connor Aud. "Versican — An Extracellular Matrix Approach to Eliminate Disparities." Eric 8 p.m. Volleyball vs. Ohio Northern U. WU/ Complex. 935-4705. 454-8981. Molecule that Regulates Cellular P. Newman Education Center. For more ASICS National Invitational. Athletic Phenotype." Thomas N. Wright, din, 3 p.m. Energy, Environmental & Chemical info. & to register: publichealth.wustl.edu. Complex. 935-4705. Benaroya Research Inst. at Virginia Mason. Saturday, Sept. 19 Engineering Seminar Series. "Overview of McDonnell Medical Sciences Bldg., 3:30 p.m. History Colloquium. "Hybrid Technologies at the Johns Hopkins 9:30 a.m. Volleyball vs. U. of La Verne. Rm. 426. 362-6950. Institutions/Local Solutions: The Iwakura Saturday, Sept. 12 University Applied Physics Laboratory." Annual Teri Clemens Invitational. Athletic Colony and Academic Psychiatry in Prewar 12:30 p.m. Volleyball vs. Concordia Victor McCrary, pres., National Org. of Black Complex. 935-4705. Chemists & Chemical Engineering. 1 p.m. Football vs. Wittenberg U. Francis Co-sponsored by the Chemistry Dept. Field. 935-4705. Louderman Hall, Rm. 458. 935-5548. Millet to open Writing Program Reading Series Sept. 17 5 p.m. Volleyball vs. U. of St. Thomas. 4 p.m. Chemistry Seminar. "On the Nature of Annual Teri Clemens Invitational. Athletic Electronically Excited and Ionized States of Fiction writer Lydia Millet will read from her work written (as writers are instructed books should be) as Complex. 935-4705. the Anionic Form of the Green Fluorescent at 8 p.m. Sept. 17 in Duncker Hall, Room 201, if it were the writer's last," wrote Publisher's Weekly. Protein Chromophore." Anna I. Krylov, prof, Hurst Lounge to open the Writing Program in Arts "Millets sad and infinitely touching third novel... is of chemistry, U. of Southern Calif. McMillen & Sciences' fall Reading Series. such an extraordinary work." ^——^■—--•— Lab., Rm. 311.935-6530. Millet is the author of six novels, beginning with Other novels include the tragicomic "Everyone's A f%gi "\J[ f\Vf* 4 p.m. Vision Science Seminar Series. "The the subversive coming-of-age tale "Omnivores," Pretty," about an alcoholic pornographer seeking x*J.MU. JLTJL\f JL V Role of Neurturin and RET in Retinal Development and Function." Milam A. which centers on a young woman whose megaloma- immortality; "Oh Pure and Radiant Heart," which Brantley, asst. prof, of ophthalmology. niac father turns their home into an armed camp images Robert'Oppenheimer, Enrico Fermi and Leo Saturday, Sept. 12 Maternity Bldg., Rm. 725.362-3315. after seceding from the United States. Her second Szilard transported to contemporary America to 8 p.m. Center for the Study of Ethics & 4:15 p.m. Earth & Planetary Sciences novel, the political satire "George Bush, Dark Prince survey the legacy of the Manhattan Project; and Human Values Performance and Panel Colloquium. "Interaction Between Iron of Love," tells the story of a trailer park denizen who "How the Dead Dream," a black comedy about an Discussion. "Dancing Who I Am." Part of Respiring Bacteria and Iron (0xy)(Hydr) becomes obsessed with the 41st president. ambitious Los Angeles real estate developer. "Ethnic Profiling: A Challenge to Democracy Oxides." Andrew Stack, asst. prof, of earth Millet's third novel, "My Happy Life" — which Her latest book is the forthcoming story collec- Series." Edison Theatre. 935-9358. & atmospheric sciences, Ga. Inst. of won the 2003 PEN-USA Award for Fiction — follows Technology. Earth & Planetary Sciences tion "Love in Infant Monkeys." Saturday, Sept. 19 Bldg., Rm. 203. 935-5610. a nameless woman who, abandoned in a derelict The talk is free and open to the public. A recep- hospital for the mentally ill, spends her days writing tion will follow. 11 a.m. Football Tailgate Party. Danforth 5 p.m. Assembly Series. Jessica Jackley, University Center Courtyard. 935-3964. co-founder, Kiva.org. Simon Hall, May Aud. memories on the walls. For more information, call 935-7130 or e-mail 935-5285. "Occasionally, a book comes along that is truly David Schuman at [email protected]. 6 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS

Constitution Day panel to examine internment camps

The Gephardt Institute for the Thomas E Eagleton University Public Service will commem- Professor, will serve as moderator. orate Constitution Day with a "It has been personally reward- panel discussion titled "Did the ing for me to work on this event," Japanese American Internment said Robin Hattori, program Violate Constitutional Rights ... director for the Gephardt Insti- and Why Do We Care?" at 7 p.m. tute. "Both of my parents were Sept. 17 in the Danforth among the Japanese Americans University Center, Room 242. interned during World War II in The discussion, part of the Rohwer, Ark., and the debate "Ethnic Profiling: A Challenge to around ethnic profiling and con- Democracy" series of the Center stitutional rights remains relevant for the Study of Ethics and today." Human Values, ties in with the Constitution Day is a day of Freshman Reading Program's observance that recognizes the exploration of Julie Otsukas novel, ratification of the U.S. Consti- "When the Emperor was Divine." tution and those who have be- Panelists include John Haley, come U.S. citizens. It is observed J.D., the William R. Orthwein on Sept. 17, the day the Consti- Distinguished Professor of Law; tutional Convention signed the Denise Lieberman, J.D., lecturer document in 1787. in political science in Arts & A reception in Danforth Sciences; and Wendy Roll, presi- University Center Formal Lounge dent of the St. Louis chapter of will follow the discussion. For the Japanese American Citizens more information, contact the League. Randall Calvert, Ph.D., Gephardt Institute at 935-9104. WOUld yOU like mUStard With yOUr MBA? "Chef" Mahendra Gupta, Ph.D. (right), dean and the Geraldine J. and Robert L. Virgil Professor of Accounting and Management at Olin Business School, serves burgers to hungry business-school students on the first day of Wireless Internet enhancements classes at the 15th annual Olin Welcome Cookout. More than 1,000 students, staff and faculty gathered in the Simon Hall Lopata Courtyard Aug. 26 for the end-of-summer tradition. Joe Fox improve connectivity across WUSTL (in baseball cap), associate dean for MBA programs, also took a turn at the serving table, which featured hamburgers, veggie burgers, pulled pork and baked beans. Wireless network users can now into the Danforth Campus wire- use one set of personal cre- less system, easing access to the dentials to securely access the network. It is no longer necessary Internet from any Washington • to download a special access the participants used both a co- sound frequencies." University wireless hotspot. program. chlear implant and a hearing aid, Potts said the brain learns to Medical Campus wireless users "Using the WUSTL KEY makes Implant integrate these two separate sig- speech recognition improved by can connect to the Medical the wireless service more user- Speech recognition an average of 14 percent over nals. The sound signals meet in School's secure wireless Internet friendly and reduces the number when they used just an implant or the brainstem and cross all along improved 14 percent while on the Danforth Campus, of steps required to access the just a hearing aid. When both the auditory pathway up to the - from Page 1 North Campus or West Campus. secure wireless connection, saving brains hearing centers, which devices were active, participants The WUSTL secure wireless net- valuable time for students, faculty also made fewer mistakes in de- interpret the signals as one sound. work also is accessible while on and staff on the Danforth termining sound direction — they When asked about their sub- School of Medicine for cochlear the Medical Campus. Campus," said Jan Weller, assistant were better able to say which jective sense of how well they implant programming and hear- Previously, each secure wireless vice chancellor for Information loudspeaker emitted sound in a heard with the devices, most ing aid fitting. network was only accessible on Services & Technology. semicircular array of 15 loud- patients said they felt they heard Because the participants were home campuses, making cross- Also guests can now access the sound better with both devices profoundly hearing impaired, the speakers placed 10 degrees apart. campus work more difficult. WUSTL wireless network on the Interestingly, when the partici- turned on. hearing aid restored only partial The capability debuted in Danforth, West and North cam- pants wore both devices, speech When both devices were on, hearing in one ear, while the May 2009. puses by using the wireless net- cochlear implant gave them a recognition and localization was they described the sound as Ed Welker, director of network work named "GuestWiFi- equally good, no matter the direc- "louder, clearer and more natu- greater level of hearing in the services, and David Hamrick, WUSTL." tion of the sound source. That was ral," "more complete" and having other ear. In addition to the im- director of information systems A user ID and password is not surprising because of the lower "a little extra depth, richness and balance in sound levels, each for the School of Medicine, led the required for guest access to sound correction in the hearing volume." device processes sound informa- implementation of a network Internet resources. aid ear. The participants — eight men tion in a unique way: A cochlear model that protects the privacy of The University has anticipated "That result really got our and 11 women — ranged in age implant translates sounds into each network, meets medical the need for strong and flexible attention," Potts said. "It shows from 26 to 79, with an average age electrical impulses that directly school HIPAA concerns and wireless coverage due to the popu- that even when patients have of 50. Almost half had some stimulate the hearing nerves of the simplifies access to Internet re- larity of smartphones and other minimal hearing with a hearing hearing impairment before age 6. inner ear, while a hearing aid sources. Additional secure ar- mobile computers, Weller said. aid, it still helps them get input But nearly all were adults amplifies sounds so the ear can rangements may still be required Technology-support personnel and helps them catch important when diagnosed with severe to sense its acoustic vibrations. to access files that are stored on across all campuses continue to sound cues. The two inputs are profound deafness. The patients' Specialists have questioned school, department or personal identify and make improvements complementing each other. ages or hearing history had no whether patients could adequately computers. to wireless access. Hearing aids are better at giving statistically significant effect on integrate the asymmetric signals Additional wireless network For more information about temporal speech cues, while im- the results of the hearing tests from implants and hearing aids. improvements were implemented how to access wireless networks, plants supply a fuller spectrum of conducted in the study. This study showed that when over the summer as well. visit nss.wustl.edu and click on WUSTL KEY is now integrated "Wireless." Preparation - from Page 1 Cell phone coverage improves on the Danforth Campus Update second cell Students, faculty and staff their signals near and on the number in WUSTL ENS living or working in the Washington University campus," The WUSTL Alerts system, South 40, the Village, Simon said Jan Weller, assistant vice part of the Emergency Notifi- Hall, the Danforth University chancellor for Information cation System (ENS), uses contact Center or the Knight Center Services 8c Technology. information provided by students, might have noticed their cell Several cellular towers and faculty and staff in HRMS and phone signals are much stron- antennas were installed on WebSTAC/SIS to send informa- ger this fall than when spring campus by carriers, and the tion about an emergency to cell semester ended last May. University also constructed a phones as text and voice messages This summer, WUSTL's Distributed Antenna System as well as to <§>wustl.edu e-mail ■ Information Services and Tech- (DAS) to address in-building addresses. nology (IS&T) and Facilities cellular reception in Simon Hall, WUSTL community members continued to worked with five the Knight Center, the Danforth who have already updated their of the St. Louis area's most University Center and its under- contact information but have popular cellular carriers — ground garage. The DAS uses more than one cell phone or pager More than 700 hand sanitizers are being installed on WUSTL AT&T, Sprint, T-Mobile, US antennas placed throughout number are encouraged to log in campuses, including this one in Goldfarb Hall. Cellular and Verizon — to buildings to capture and relay and include both numbers in their improve cell phone reception cell phone signals through HRMS or WebSTAC/SIS profile. information," said Matt Arthur, will only be used during emer- for the residential areas of the interior space. Those who have not yet updated director of incident communica- gency situations, Arthur said. They Danforth Campus and for The growth of mobile com- their contact information in tions solutions. will not be shared with outside targeted buildings such as the puting and the widespread use HRMS or WebSTAC/SIS are "Only those with current infor- vendors or used for other Danforth University Center, of smartphones require strong encouraged to do so as soon as mation in HRMS or WebSTAC/ purposes. Knight Center and Simon Hall. wireless coverage, Weller said. possible. SIS can receive the emergency As of Sept. 1, 58 percent of "Requests for stronger cel- IS&T continues to look for ways Parents, family and others may messages," Arthur said. "That's faculty and staff and 55 percent of lular signals from residential to improve cellular reception register to receive emergency why it's vital that each WUSTL students had provided the Univer- students as well as Student throughout the Danforth information messages by follow- student, faculty and staff member sity with cell phone numbers that Union officers and Congress of Campus and other WUSTL ing the links at emergency.wustl. updates his or her contact infor- can be used for WUSTL Alerts. the South 40 representatives in campuses, partnering with cell edu. mation. Parents of students are To update contact information, recent years — specifically in phone carriers to create a "Text messaging has proved to encouraged to provide their cell log on to HRMS or WebSTAC/SIS the residence halls — prompted "seamless" communications be an effective and efficient way to phone numbers as well via the or visit emergency.wustl.edu and the University to work with environment at WUSTL, reach members of a university emergency Web site." follow the link on the left side of cellular carriers to enhance Weller said. community with emergency Cell phone numbers provided the Web page. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 10,2009 7 Notables

Institute for Public Health Of note appoints faculty scholars Mutharika to be installed Haluk Ergin, Ph.D., associate as Nagel Professor Sept. 14 BY DIANE DUKE WILLIAMS research assistant professor of professor of economics in Arts & Sciences, has received a three- psychiatry, has received funding for sorship possible. year, $201,644 grant from the BY JESSICA MARTIN The Institute for Public Health his project titled "Linking Gene- Prior to his cabinet position, National Science Foundation for (IPH) has appointed 131 cam- tically Informative Addiction Data Mutharika served as chief research titled "A Subjective t. Peter Mutharika, J.S.D., pus-wide faculty scholars. Sets to Objectively Measured adviser to his brother, Malawi Model of Temporal Preferences." will be installed as the These scholars, appointed for three- Environmental Data via Gep- President Bingu wa Mutharika, Also receiving the grant was Todd Charles Nagel Professor of year, renewable terms, have been coding." on constitutional, legal and Sarver, Ph.D., of Northwestern International and Comparative chosen on the basis of their re- • Christine Hoehner, Ph.D., international affairs. University. ... Law at 4:30 p.m. Monday, search and teaching interests in assistant professor of surgery, has An expert on international Kyra Krakos, graduate student Sept. 14, in Anheuser-Busch public health and willingness to received funding for her project economic law, international law in biology in Arts & Sciences, has Hall, Room 309. engage in collaborative work with titled "Health Impact Assessment: and comparative constitutional received a one-year, $1,500 grant Mutharika is on leave from other institute scholars. Promoting Health Priorities in law, Mutharika is the author of from the Webster Groves Nature the University serving his native Scholars are eligible for small Policy, Planning and Design." numerous books and articles, Study Society for research tided country of Malawi. In June team grants to foster interdisciplin- • Susan B. Racette, Ph.D., assis- including his forthcoming book "Specialization of Pollination 2009, he was appointed to the ary programs and projects. They tant professor of physical therapy on international trade, "Foreign Systems in Oenothera." ... presidential cabinet as minister also will be invited to attend and and of medicine, has received Investment Security in Sub- Allan Larson, Ph.D., professor of justice and constitutional participate in institute programs, funding for her project tided Saharan Africa: The Emerging of biology in Arts & Sciences, and affairs. In a recent election, he lectures and workgroups on public "Nourishing an Urban Commun- Policy and Legal Frameworks." Joshua Reece, graduate student in also won a seat in Malawi's health issues. ity: Phase I." He was the 2008 recipient of biology, have received a one-year, Parliament with 82 percent of Additionally, scholars will work Additionally, the IPH's second the International Jurist Award. $9,020 grant from the National the vote. with a University network of indi- annual conference, "Multidiscipli- Among other professional Science Foundation for research Nagel, LL.B. 1875, was U.S. viduals already conducting public nary Approach to Eliminate activities, Mutharika serves as titled "Phylogenetics and Phylo- Secretary of Commerce and health research and be encouraged Disparities," will be held from adviser to the American Bar geography of Moray Eels (Murae- Labor under William Howard to collaborate on multidisciplinary 1-6:15 p.m. Sept. 23 in the Eric Association's Rule of Law Ini- nidae): the First Coral Reef Fishes Taft; a member of the Missouri research and program development P. Newman Education Center. tiative for Africa. With Panmictic Populations House of Representatives, a projects. Over time, the institute Felton Earls, M.D., professor of He continues his work as Throughout the Entire Indo- member of the University's will develop infrastructure to foster human behavior and development a member of the Panel of Pacific." ... Board of Directors and a part- collaborative public health re- at the Harvard School of Public Arbitrators and Panel of Richard A. Loomis, Ph.D., time law lecturer. search, teaching and service across Health, will deliver a keynote ad- Conciliators for the Inter- associate professor of chemistry The estate of Nagel's law the University. dress at 1:15 p.m., followed by a national Centre for Settlement in Arts & Sciences, has received a partner, Daniel Noyes Kirby, A complete list of faculty is panel discussion. LL.B. 1888, made the profes- of Investment Disputes. available at publichealth.wustl.edu/ Bruce Lindsey, Ph.D., dean of three-year, $356,048 grant from people/pages/facultyscholars.aspx. the Sam Fox School's College of the National Science Foundation For faculty interested in becoming Architecture and Graduate School for research titled "Experimental and Mental Health Practices in professor, Michael E. Wysession, IPH faculty scholars, e-mail of Architecture & Urban Design Interrogation of Exciton Dynam- India." ... associate professor, and [email protected]. and the E. Desmond Lee Professor ics Within One-Dimensional Yinjie Tang, Ph.D., assistant Viatcheslav Solomatov, Ph.D., The IPH also announced the for Community Collaboration, will Semiconductor Quantum professor of chemical engineer- professor, all in the Department first three recipients of the deliver another keynote address at Materials." ... ing, has received a three-year, of Earth and Planetary Sciences Interdisciplinary Public Health 3:45 p.m. Anubha Sood, graduate stu- $48,900 subcontract from the in Arts & Sciences, have received Project grants. These recipients, all The conference will conclude dent in anthropology in Arts & University of California, Berkeley, a two-year, $74,881 grant from IPH scholars, will be part of new with a poster session and reception. Sciences, has received a one-year, for research tided "Molecular the National Science Foundation groups that will produce innovative For more information or to regis- .$1,790 grant from the Wenner- Studies of 1.4-Dioxane-Utilizing for research tided "Acquisition of proposals to tackle significant ter, visit publichealth.wustl.edu/ Gren Foundation for research Bacterium Pseudonocardia a New Linux-Based Computer public health problems. news/Pages/2009 Annual tided "Women's Help-Seeking Dioxanivorans." ... System for Geophysical • Richard Grucza, Ph.D., Conference.aspx. Pathways: Global Policy, the State Douglas A. Wiens, Ph.D., Research."

Bret Gustafson, Ph.D., assistant professor of anthropology in Arts & Sciences Men's soccer unbeaten Imergoot memorial New Languages of the State: Indigenous Resurgence through first week The men's soccer team posted a A memorial service for pair of ties and a win during the Lynn Imergoot, associate direc- anil the Politics of Knowledge In Bolivia first week of the 2009 season. In tor of intramurals and club sports and former women's Duke University Press (2009) the season opener against Illinois - Wesleyan University Sept. 1, se- tennis coach, takes place at 2 p.m. Sunday, Sept. 13, in Bret Gustafson, Ph.D., assis- language and cultural rights, nior goalkeeper John Smelcer tied his career high of 10 saves in a Graham Chapel. Doors will tant professor of anthropol- and the Guarani did work to open at 1:30 p.m. ogy in Arts & Sciences, has improve their schools. This in 0-0 tie. The Bears then hit the road, Following the one-hour spent more than 14 years in itself was significant. However, ceremony, a reception will be Bolivia. B^E! it also was used to gain a larger traveling to Greenville, Ohio, for the Denison University Invita- held in the Women's Building His early research focused voice in the regional and na- Formal Lounge. on language and culture to tional society. It thus had a tional. Senior Nat Zenner and help promote the inclusion of kind of democratizing effect, junior Cody Costakis each scored the indigenous Guarani lan- ;: even though this was not how in a 2-0 win over Rose-Hulman a pair of 3-0 wins over Harris- guage, history and culture into S many elites imagined its pur- Institute of Technology. WUSTL Stowe State University and the public school system in A poses to be." then tied tournament host Deni- Greenville College Sept. 1. Bolivia. As with many indig- i y, , i The book retraces the con- son, 1-1, behind another goal from The Bears then hosted the 2009 enous peoples across the flicts and debates over school- Zenner. Bears Classic Tournament, where Americas, the education sys- ing and looks in-depth at how The men's soccer team returns they finished in second place with tem has long been biased OF THE STATE different personal histories to action at 7 p.m. Thursday, a 3-1 record. The Bears defeated against native peoples. It has come together in this complex Sept. 10, at Webster University. Webster University, Millikin University and Augustana College sought to do away with their. Indigenous Resurgence and the development project. It con- languages and their specific Politics of Knowledge in Bolivia cludes that, however limited, Women's soccer 1-2 but fell to No. 22 Hope College. identities. the transformation of national WUSTL returns to action in opening week Friday, Sept. 11, when it hosts the Recently, Gustafson's re- BRET GUSTAFSON education systems to recognize search has expanded beyond indigenous rights does have The No. 8-ranked women's soccer WU/Asics National Invitational. the Guarani into an ethno- democratizing effects rather team posted a 1-2 record in the The Bears face No. 13 Pacific graphic study of the Bolivian than creating radical extrem- first week of the season. Lutheran University at 5:30 p.m. After back-to-back losses to and No. 6 Ohio Northern state. This research sought to — intersected ongoing political ists, which many opponents of Illinois Wesleyan University and University at 8 p.m. use ethnography to shed light and social conflicts at different indigenous schooling argue. No. 6 Johns Hopkins University, on a complex process of educa- levels of Bolivian society," he said. The book has relevance to the Bears responded with a 2-1 tion reform. Through researching his new scholars of many disciplines Football loses season upset victory over No. 4 William "Anthropologists tradition- book, Gustafson found that edu- who study international opener to Greenville ally work in small communi- development. Smith College Sept. 6 in Balti- cation reform at the level of the The football team dropped its ties and are expected to dis- "Though deeply rooted in more. centralized government Was more season opener against Greenville cover something unique about Bolivian history, culture and The Bears host the four-team about the restructuring of state College Sept. 5 at Francis Field. a particular place or culture," politics, this work sheds light Washington University Classic this bureaucracies — and the political The Bears, who dropped to he said. "Yet, todays anthro- on a global dilemma: how to weekend. WUSTL takes on No. 23 relations that sustained these 16-5 all-time in season openers pologists of my generation are create models of state and ranked Claremont-Mudd-Scripps — than it was about the actual under head coach Larry Kindbom, also looking at complex social society that include people in Colleges at 7 p.m. Friday, Sept. 11, education outcomes, or the issue were limited to 167 yards of total and political processes, at the opportunities of knowledge and Grinnell College at 7 p.m. of indigenous rights. This contra- offense and committed four turn- different scales. and economy without margin- Saturday, Sept. 12. dicted how donors talked about overs. Senior quarterback Stephen "So, my purpose was to alizing them racially or cultur- their aid and its purposes. Sherman connected with junior understand how large-scale ally or denying them their Volleyball finishes "At the level of local move- Tom Gulyas on a 53-yard touch- development projects like particularity," Gustafson said. ments like the Guarani, education second at tourney down pass for the lone score. school reform — much of it also had a political meaning," The No. 5 volleyball team is 5-1 WUSTL returns to action at financed by external donors — Neil Schoenherr Gustafson said. "It was about after its first week of action. 1 p.m. Saturday, Sept. 12, at WUSTL began the season with Westminster College. 8 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 10,2009 Washington People

To children in her son Greg's school, Anne Fagan is known as "the brain lady." "I love getting kids fired up about the brain," says Fagan, Ph.D., research associate professor of neurology. "I'll go to Greg's school to talk about the brain, and I'll bring actual brains with me. It's an innately interest- ing topic, and they're fascinated BY MICHAEL C. PURDY by it." Fagan studies Alzheimer's disease in the laboratory of David Holtzman, M.D., the Andrew B. and Gretchen P. Jones Professor and head of Neurology. She also is an investigator at the Alzheimer's Disease Research Center (ADRC). Fagan remembers the exact moment she became hooked on the brain: She was a junior in high school, and her physiology teach- er assigned a term paper on the "biochemistry of madness." "That was my first introduc- tion to the concept that brain chemicals and neurons actually influence how you feel and think, Rebecca Craig-Schapiro (left), an M.D./Ph.D. student, works with Anne Fagan, Ph.D., in Fagan's lab in not just how you move and have the Biotech Building at the School of Medicine. "Anne is simply an amazing person," says David senses," she says. "I just thought, Holtzman, M.D., the Andrew B. and Gretchen P. Jones Professor and head of Neurology. "Trained as a 'How cool is that?"' basic neuroscientist, she has become one of the most respected leaders in an important area of Fagan also knew one other translational science, biomarkers for Alzheimer's disease. She's also a great colleague, friend and thing early in life: Family would teacher." come first for her. things Washington University had to go down in the CSF as amyloid at sports as a kid, but it comes to offer, he had to sell me builds up in the brain. For pre- easy to him. He's a good student, on moving to St. Louis," Fagan dicting which cognitively normal too. He's a very well-rounded kid." Family comes first says. "I was a coastal gal, and persons will go on to develop As a member of the research St. Louis was just a place that I dementia, the most promising faculty, Fagan is not formally "When I say that, I don't mean was always flying over to get to marker so far is the ratio of amy- involved in the development and Fagan balances that I would abandon my work where I really wanted to be. loid beta 42 levels to levels of tau implementation of medical school because I love what I do, and it's "I was such a snob, but I love it proteins, a family of proteins curricula. But she still has oppor- roles as single very important to me," she says. here now," she says, laughing. associated with neurofibrillary or tunities to give special lectures to "But in the end, relationships are nerve fiber tangles in the brain medical students, residents and mom, leader in what hold me together. If I don't Catching that also are characteristic of visiting scholars, and to mentor Alzheimer's have good family and friend Alzheimer's early Alzheimer's disease. and advise young students. relationships, then the rest of my At Washington University, Fagan In 2006, Fagan was lead author "Many young women have research life is meaningless." began her research career with on a study where she and others at come to me because it seems to studies of apolipoprotein E the ADRC worked with Mark them like I have the ideal job, 'Coastal gal' to Midwest (ApoE). Variations in the gene for Mintun, M.D., professor of radiol- successfully combining work and Fagan grew up in Marion, Mass., ApoE affect Alzheimer's risk. ogy, of psychiatry and of neurobi- family, and I would have to agree: on Cape Cod. She earned a doc- Through tissue culture and geneti- ology, to use medical science's first I've carved out a place that works torate in neuroscience at the cally modified mouse models, successful amyloid imaging agent for me," Fagan says. University of California, San Fagan and Holtzman were instru- to check the predictions they were Fagan appreciates both the Diego, under the mentorship of mental in establishing the impor- developing based on analyses of friendly, family-oriented atmo- Fred H. Gage, Ph.D., professor of tant relationship between the volunteers' CSF. They found that sphere of St. Louis and the colle- biology at the Laboratory of different forms of human'ApoE they could use the CSF studies to giality of the University. She Genetics at the Salk Institute. and the amyloid beta 42 peptide, predict whether imaging results found the support of both com- Anne Fagan "Anne is filled with energy, the key ingredient of brain plaques would show increased amyloid in munities essential during the past very bright, dedicated and ex- seen in Alzheimer's patients. They subjects' brains. year as she dealt with two major Bom in: Milwaukee tremely hardworking," Gage says. showed that ApoE is involved in The Annals of Neurology, health problems. "She's also great fun. to be around amyloid beta transport and aggre- which published the study, award- "My heart stopped for seven Favorite local performing artists: — she's very, very upbeat." ed Fagan and her co-authors the minutes in 2001 at my father's The Saint Louis Symphony Orchestra gation, and that some versions of Gage says that Fagan left his ApoE are more effective contribu- "Highest Impact Paper of the funeral, and I had to be shocked Favorite composer: Mozart lab 17 years ago, but he and others tors to these processes than Year" award. The Alzheimer's back to life," Fagan says. "They in his lab stay in touch with her. Association also recognized the thought it was vasospasm but Best advice for graduate students: others. "She's had a long-lasting im- paper by awarding Fagan its "Alz- couldn't confirm it until I came "Ask the right questions." One challenge of human pact on my lab, and we continue Alzheimer's has always been that it heimer's Disease Neuroimaging back with symptoms after a ski Favorite restaurants to visit with to follow her career with great takes place in the brain, an area of Award, New Investigator." trip in April 2008, and that led to son, Greg: Shogun and Longhorn joy," he says. extremely limited access. But the "Anne is simply an amazing the implantation of a cardiac Steakhouse In Gage's lab, Fagan studied cerebrospinal fluid (CSF) that person," Holtzman says. "Trained defibrillator." Likes to read: Nonfiction, historical neurotrophins, nerve cell growth circulates through the brain also as a basic neuroscientist, she has Later the same year, Fagan fiction and mysteries factors that had just come to the moves through the spinal canal become one of the most respected was diagnosed with nasopharyn- attention of scientists. One neuro- and can be safely sampled via a leaders in an important area of geal cancer, a rare and dangerous Also a fan of: The Harry Potter trophin was connected to the translational science, biomarkers but potentially treatable form of series routine procedure known as a cholinergic system, a brain system lumbar puncture. for Alzheimer's disease. She's also cancer. She went through 33 hit particularly hard by Alzheim- Fagan and her colleagues at the a great colleague, friend and rounds of "brutal" radiation treat- er's disease. Through this connec- ADRC started studying CSF sam- teacher." ments, two rounds of chemother- tion and the ples from research volunteers to apy and three hospitalizations in research collabo- see if they could use a variety of Being the mom as many months. rations it in- indicators in the CSF to diagnose she wants to be "I am happy to report that I spired, Fagan Alzheimer's before clinical symp- Fagan is grateful for the "out- am cancer-free today and starting came to know toms start. standing" mentoring she has to bounce back physically," Fagan Holtzman, who "The emphasis here at Wash- received from Holtzman and the says. "Everyone has been and was then study- ington University has always been opportunities that being a mem- continues to be unbelievably ing Alzheimer's on early-stage and preclinical ber of his lab gives her to "be the supportive — Dave (Holtzman), disease at the detection, years or even decades mom I want to be." the lab, the entire ADRC commu- University of before symptoms begin," Fagan "Sometimes I leave work after nity, my family, my 'village' of California, San says. "When symptoms appear, a long day, and I'll say, 'OK, off to friends and church members and Francisco. Alzheimer's has already done a my real job,"' Fagan says. "Women Greg." In 1995, great deal of damage to the brain, nod knowingly." Fagan also is grateful to her lab Holtzman, in the so we have stressed the need to Fagan has been a single parent staff, who kept her research pro- process of mov- find a way to start treatment be- to Greg, 12, since 2001. She says gram going "admirably" while she ing to Washing- fore that point." they "love to be out and about" was absent. ton University to Fagan and her collaborators - and can often be found biking, She says with a laugh that the establish his own have examined several factors in hiking or engaging in other fun one thing that really threw Greg lab, asked Fagan CSF as potential biomarkers, or activities away from home, in- for a loop was that her hair post- to join his re- indicators that correlate with the cluding both spectator sports and treatment is now gray. search team. future onset of Alzheimer's. These Greg's many athletic activities. "Other people like it; I'm tak- ___ _ "Before I saw ing votes on whether or not to Anne Fagan (right) and her son, have included CSF levels of amy- "Greg is lucky; he's a real natu- Greg, on a Boy all the wonderml Scout camping trip. loid beta 42 peptide, which tend ral athlete," Fagan says. "I worked keep it," she jokes.