A Recurrent Point Mutation in PRKCA Is a Hallmark of Chordoid Gliomas
A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas Shai Rosenberg, Iva Simeonova, Franck Bielle, Maïté Verreault, Bertille Bance, Isabelle Le Roux, Mailys Daniau, Arun Nadaradjane, Vincent Gleize, Sophie Paris, et al. To cite this version: Shai Rosenberg, Iva Simeonova, Franck Bielle, Maïté Verreault, Bertille Bance, et al.. A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas. Nature Communications, Nature Publishing Group, 2018, 9 (1), pp.2371. 10.1038/s41467-018-04622-w. hal-01858239 HAL Id: hal-01858239 https://hal-amu.archives-ouvertes.fr/hal-01858239 Submitted on 7 Jan 2019 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Distributed under a Creative Commons Attribution| 4.0 International License ARTICLE DOI: 10.1038/s41467-018-04622-w OPEN A recurrent point mutation in PRKCA is a hallmark of chordoid gliomas Shai Rosenberg 1,2, Iva Simeonova1, Franck Bielle1,3, Maite Verreault1, Bertille Bance1, Isabelle Le Roux1, Mailys Daniau1, Arun Nadaradjane1, Vincent Gleize1, Sophie Paris1, Yannick Marie1,4, Marine Giry1, Marc Polivka5, Dominique Figarella-Branger6, Marie-Hélène Aubriot-Lorton7, Chiara Villa8, Alexandre Vasiljevic9, Emmanuèle Lechapt-Zalcman10, Michel Kalamarides1,11, Ariane Sharif12, Karima Mokhtari1,3, Stefano Maria Pagnotta13,14, Antonio Iavarone14,15, Anna Lasorella14,16, Emmanuelle Huillard1 & Marc Sanson1,4,17,18 1234567890():,; Chordoid glioma (ChG) is a characteristic, slow growing, and well-circumscribed diencephalic tumor, whose mutational landscape is unknown.
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