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(1-Methylethylidene)Bis[2, 6-Dibromophenol] CASRN 79-94-7

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(1-Methylethylidene)Bis[2, 6-Dibromophenol] CASRN 79-94-7 EPA Document # 740-D-20-008 April 2020 United States Office of Chemical Safety and Environmental Protection Agency Pollution Prevention Draft Scope of the Risk Evaluation for 4,4′-(1-Methylethylidene)bis[2, 6-dibromophenol] CASRN 79-94-7 April 2020 TABLE OF CONTENTS ACKNOWLEDGEMENTS ...................................................................................................................... 5 ABBREVIATIONS AND ACRONYMS ................................................................................................. 6 EXECUTIVE SUMMARY ....................................................................................................................... 8 1 INTRODUCTION ........................................................................................................................... 11 2 SCOPE OF THE EVALUATION .................................................................................................. 11 2.1 Reasonably Available Information ............................................................................................. 11 Search of Gray Literature ....................................................................................................... 12 Search of Literature from Publicly Available Databases (Peer-Reviewed Literature) .......... 13 Search of TSCA Submissions ................................................................................................ 18 2.2 Conditions of Use ....................................................................................................................... 19 Categories and Subcategories of Conditions of Use Included in the Scope of the Risk Evaluation .............................................................................................................................. 20 Activities Excluded from the Scope of the Risk Evaluation .................................................. 22 Production Volume ................................................................................................................ 22 Overview of Conditions of Use and Lifecycle Diagram ....................................................... 22 2.3 Exposures ................................................................................................................................... 24 Physical and Chemical Properties .......................................................................................... 24 Environmental Fate and Transport......................................................................................... 24 Releases to the Environment .................................................................................................. 24 Environmental Exposures ...................................................................................................... 26 Occupational Exposures......................................................................................................... 26 Consumer Exposures ............................................................................................................. 27 General Population Exposure ................................................................................................ 28 2.4 Hazards (Effects) ........................................................................................................................ 28 Environmental Hazards .......................................................................................................... 28 Human Health Hazards .......................................................................................................... 28 2.5 Potentially Exposed or Susceptible Subpopulations .................................................................. 29 2.6 Conceptual Models ..................................................................................................................... 29 Conceptual Model for Industrial and Commercial Activities and Uses ................................ 29 Conceptual Model for Consumer Activities and Uses ........................................................... 32 Conceptual Model for Environmental Releases and Waste: Potential Exposures and Hazards ............................................................................................................................................... 34 2.7 Analysis Plan .............................................................................................................................. 36 Physical and Chemical Properties and Environmental Fate .................................................. 36 Exposure ................................................................................................................................ 37 2.7.2.1 Environmental Releases .................................................................................................. 37 2.7.2.2 Environmental Exposures ............................................................................................... 39 2.7.2.3 Occupational Exposures ................................................................................................. 40 2.7.2.4 Consumer Exposures ...................................................................................................... 42 2.7.2.5 General Population ......................................................................................................... 43 Hazards (Effects) ................................................................................................................... 46 2.7.3.1 Environmental Hazards .................................................................................................. 46 2 2.7.3.2 Human Health Hazards ................................................................................................... 47 Summary of Risk Approaches for Characterization .............................................................. 49 2.8 Peer Review ................................................................................................................................ 50 REFERENCES ........................................................................................................................................ 51 APPENDICES ......................................................................................................................................... 58 E.1.1 Manufacture (Including Import) ............................................................................................ 69 E.1.1.1 Domestic Manufacturing ................................................................................................ 69 E.1.1.2 Import ............................................................................................................................. 69 E.1.2 Processing and Distribution ................................................................................................... 69 E.1.2.1 Processing as a Reactant ................................................................................................. 69 E.1.2.2 Incorporated into a Formulation, Mixture or Reaction Product ..................................... 69 E.1.2.3 Incorporated into an Article ............................................................................................ 69 E.1.2.4 Recycling ........................................................................................................................ 69 E.1.3 Uses Included in Scope .......................................................................................................... 70 E.1.3.1 Adhesive Manufacturing ................................................................................................ 70 E.1.3.2 Intermediate (e.g., transportation equipment manufacturing) ........................................ 70 E.1.3.3 Intermediate (e.g., all other chemical product and preparation manufacturing) ............ 70 E.1.3.4 Building/Construction Materials .................................................................................... 70 E.1.3.5 Electrical and Electronic Products .................................................................................. 70 E.1.3.6 Plastic Products and Resins ............................................................................................ 71 E.1.3.7 Fabric, Textiles and Leather Products not Covered Elsewhere ...................................... 71 E.1.3.8 Batteries .......................................................................................................................... 72 E.1.3.9 Laboratory Chemical ...................................................................................................... 72 E.1.3.10 Disposal .......................................................................................................................... 72 3 LIST OF TABLES Table 2-1 Results of Title Screening of Submissions to EPA Under Various Sections of TSCA ............... 19 Table 2-2 Categories and Subcategories of Conditions of Use Included in the Scope of the Risk Evaluation ............................................................................................................................ 20 Table 2-3 Summary of TBBPA TRI Production-Related Waste Managed in 2018 .................................... 25 Table 2-4 Summary of Releases of TBBPA to the Environment During 2018 ........................................... 25 Table 2-5 Categories and Sources of Environmental Release Data ............................................................. 37 LIST OF FIGURES Figure 2-1 Gray 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