Program and Abstracts of the Annual Meeting of the Georgia Academy of Science, 2009
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Fish Consumption Guidelines: Rivers & Creeks
FRESHWATER FISH CONSUMPTION GUIDELINES: RIVERS & CREEKS NO RESTRICTIONS ONE MEAL PER WEEK ONE MEAL PER MONTH DO NOT EAT NO DATA Bass, LargemouthBass, Other Bass, Shoal Bass, Spotted Bass, Striped Bass, White Bass, Bluegill Bowfin Buffalo Bullhead Carp Catfish, Blue Catfish, Channel Catfish,Flathead Catfish, White Crappie StripedMullet, Perch, Yellow Chain Pickerel, Redbreast Redhorse Redear Sucker Green Sunfish, Sunfish, Other Brown Trout, Rainbow Trout, Alapaha River Alapahoochee River Allatoona Crk. (Cobb Co.) Altamaha River Altamaha River (below US Route 25) Apalachee River Beaver Crk. (Taylor Co.) Brier Crk. (Burke Co.) Canoochee River (Hwy 192 to Ogeechee River) Chattahoochee River (Helen to Lk. Lanier) (Buford Dam to Morgan Falls Dam) (Morgan Falls Dam to Peachtree Crk.) * (Peachtree Crk. to Pea Crk.) * (Pea Crk. to West Point Lk., below Franklin) * (West Point dam to I-85) (Oliver Dam to Upatoi Crk.) Chattooga River (NE Georgia, Rabun County) Chestatee River (below Tesnatee Riv.) Conasauga River (below Stateline) Coosa River (River Mile Zero to Hwy 100, Floyd Co.) Coosa River <32" (Hwy 100 to Stateline, Floyd Co.) >32" Coosa River (Coosa, Etowah below Thompson-Weinman dam, Oostanaula) Coosawattee River (below Carters) Etowah River (Dawson Co.) Etowah River (above Lake Allatoona) Etowah River (below Lake Allatoona dam) Flint River (Spalding/Fayette Cos.) Flint River (Meriwether/Upson/Pike Cos.) Flint River (Taylor Co.) Flint River (Macon/Dooly/Worth/Lee Cos.) <16" Flint River (Dougherty/Baker Mitchell Cos.) 16–30" >30" Gum Crk. (Crisp Co.) Holly Crk. (Murray Co.) Ichawaynochaway Crk. Kinchafoonee Crk. (above Albany) Little River (above Clarks Hill Lake) Little River (above Ga. Hwy 133, Valdosta) Mill Crk. -
Long Noncoding RNA and Cancer: a New Paradigm Arunoday Bhan, Milad Soleimani, and Subhrangsu S
Published OnlineFirst July 12, 2017; DOI: 10.1158/0008-5472.CAN-16-2634 Cancer Review Research Long Noncoding RNA and Cancer: A New Paradigm Arunoday Bhan, Milad Soleimani, and Subhrangsu S. Mandal Abstract In addition to mutations or aberrant expression in the moting (oncogenic) functions. Because of their genome-wide protein-coding genes, mutations and misregulation of noncod- expression patterns in a variety of tissues and their tissue- ing RNAs, in particular long noncoding RNAs (lncRNA), appear specific expression characteristics, lncRNAs hold strong prom- to play major roles in cancer. Genome-wide association studies ise as novel biomarkers and therapeutic targets for cancer. In of tumor samples have identified a large number of lncRNAs this article, we have reviewed the emerging functions and associated with various types of cancer. Alterations in lncRNA association of lncRNAs in different types of cancer and dis- expression and their mutations promote tumorigenesis and cussed their potential implications in cancer diagnosis and metastasis. LncRNAs may exhibit tumor-suppressive and -pro- therapy. Cancer Res; 77(15); 1–17. Ó2017 AACR. Introduction lncRNAs (lincRNA) originate from the region between two pro- tein-coding genes; enhancer lncRNAs (elncRNA) originate from Cancer is a complex disease associated with a variety of genetic the promoter enhancer regions; bidirectional lncRNAs are local- mutations, epigenetic alterations, chromosomal translocations, ized within the vicinity of a coding transcript of the opposite deletions, and amplification (1). Noncoding RNAs (ncRNA) are strand; sense-overlapping lncRNAs overlap with one or more an emerging class of transcripts that are coded by the genome but introns and exons of different protein-coding genes in the sense are mostly not translated into proteins (2). -
(12) United States Patent (10) Patent No.: US 7,807,373 B2 Srivastava Et Al
US007807373B2 (12) United States Patent (10) Patent No.: US 7,807,373 B2 Srivastava et al. (45) Date of Patent: Oct. 5, 2010 (54) PROSTATE SPECIFIC GENE, PCGEM1, AND GenBank. Accession No. ACO 13401, GI:8569780, 169700 bp DNA, METHODS OF USING PCEGM1 TO DETECT, Jul. 7, 2000. TREAT, AND PREVENT PROSTATE CANCER “AC003046.” EBI Database XPO02143197, Dec. 1, 2001. (75) Inventors: Shiv Srivastava, Potomac, MD (US); Srikantanet al., “Structure and Expression of a Novel Prostate Spe Judd W. Moul, Bethesda, MD (US); cific Gene: PCGEM1. Proc. American Assoc. Cancer Research Vasantha Srikantan, Rockville, MD Annual, XP000929230, vol. 40, p. 37 (Mar. 1999). (US); Zhiqiang Zou, Gaithersburg, MD Bussemakers et al., “A New Prostate-Specific Arker, Strongly (US) Overexpressed in Prostatic Tumors.” Urological Research, XP0020743.05, vol. 25, No. 1, p. 76 (Feb. 1997). (73) Assignee: Henry M. Jackson Foundation for the Wang et al., “Genes Regulated by Androgen in the Rat Ventral Pros Advancement of Military Medicine, tate.” Proc. Nat.1 Acad. Sci., U.S.A., vol. 94, pp. 12999-13004 (Nov. Rockville, MD (US) 1997). “ACO 13401, EBI Database XP002143200, Apr. 16, 2005. (*) Notice: Subject to any disclaimer, the term of this Srikantan et al., “PCGEM1, a Prostate-Specific Gene, Is Overex patent is extended or adjusted under 35 posed in Prostate Cancer.” Proc. Natl. Acad. Sci., vol.97, No. 22, pp. U.S.C. 154(b) by 285 days. 12216-12221 (Oct. 24, 2000). (21) Appl. No.: 12/166,723 Srikantan et al., Identification of Prostate Cancer Associated Novel Gene Expression Alterations, Proc. American Assoc. Cancer (22) Filed: Jul. -
Guidelines for Eating Fish from Georgia Waters 2017
Guidelines For Eating Fish From Georgia Waters 2017 Georgia Department of Natural Resources 2 Martin Luther King, Jr. Drive, S.E., Suite 1252 Atlanta, Georgia 30334-9000 i ii For more information on fish consumption in Georgia, contact the Georgia Department of Natural Resources. Environmental Protection Division Watershed Protection Branch 2 Martin Luther King, Jr. Drive, S.E., Suite 1152 Atlanta, GA 30334-9000 (404) 463-1511 Wildlife Resources Division 2070 U.S. Hwy. 278, S.E. Social Circle, GA 30025 (770) 918-6406 Coastal Resources Division One Conservation Way Brunswick, Ga. 31520 (912) 264-7218 Check the DNR Web Site at: http://www.gadnr.org For this booklet: Go to Environmental Protection Division at www.gaepd.org, choose publications, then fish consumption guidelines. For the current Georgia 2015 Freshwater Sport Fishing Regulations, Click on Wild- life Resources Division. Click on Fishing. Choose Fishing Regulations. Or, go to http://www.gofishgeorgia.com For more information on Coastal Fisheries and 2015 Regulations, Click on Coastal Resources Division, or go to http://CoastalGaDNR.org For information on Household Hazardous Waste (HHW) source reduction, reuse options, proper disposal or recycling, go to Georgia Department of Community Affairs at http://www.dca.state.ga.us. Call the DNR Toll Free Tip Line at 1-800-241-4113 to report fish kills, spills, sewer over- flows, dumping or poaching (24 hours a day, seven days a week). Also, report Poaching, via e-mail using [email protected] Check USEPA and USFDA for Federal Guidance on Fish Consumption USEPA: http://www.epa.gov/ost/fishadvice USFDA: http://www.cfsan.fda.gov/seafood.1html Image Credits:Covers: Duane Raver Art Collection, courtesy of the U.S. -
Alapaha Riverand Tim Suwannee Rtver from Ti{E Illegal Discharge of Raw Sewage by Tiie City of Valdosta
RESOLUTTON 2or7 -ol ARESOLUTION BY TIIE BOARD OF COUNTY COMMISSIONERS OF HAMILTON COUNTY, FLORIDA DEMANDING PROTECTION OF TIIE WITIILACOOCI{EE RTVER THE ALAPAHOOCHEE RIVER. TIM ALAPAHA RIVERAND TIM SUWANNEE RTVER FROM TI{E ILLEGAL DISCHARGE OF RAW SEWAGE BY TIIE CITY OF VALDOSTA. GEORGIA. WHEREAS, the Withlacoochee River forms the Western boundary of Hamilton County, Florida from the Florida/Georgia state line until its juncture with the Suwannee River; and WHEREAS, the Withlacoochee River provides recreational and economic benefits to the citizens of Hamilton County and others; and WHEREAS, citizens of Hamilton County depend on clean water from the Withlacoochee River watershed for activities of daily life as well as for agricultural, business, and recreational purposes; and WHEREAS, the health and welfare of many Hamilton County citizens is directly harmed by any degradation of the quality of water in the Withlacoochee River and its watershed; and WHEREAS, the City of Valdosta, Georgia over the past several years has experienced numerous failures and spills with their wastewater treatment facility; which resulted in the construction of a new facility that was placed into service in 2016; and WHEREAS, the City of Valdosta, on January 22,2017, had yet another failure which resulted in the release of 2.2 million gallons of raw sewage and stormwater into the Wthlacoochee River; and WHEREAS, the Hamilton County Health Department has issued numerous health advisories warning of the dangers of contact with the waters contaminated by sewage -
Oncotarget-05-764.Pdf
Open Research Online The Open University’s repository of research publications and other research outputs Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Journal Item How to cite: Crea, Francesco; Watahiki, Akira; Quagliata, Luca; Xue, Hui; Pikor, Larissa; Parolia, Abhijit; Wang, Yuwei; Lin, Dong; Lam, Wan L.; Farrar, William L.; Isogai, Takao; Morant, Rudolf; Castori-Eppenberger, Serenella; Chi, Kim N.; Wang, Yuzhuo and Helgason, Cheryl D. (2014). Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer. Oncotarget, 5(3) pp. 764–774. For guidance on citations see FAQs. c 2014 The Authors https://creativecommons.org/licenses/by/4.0/ Version: Version of Record Link(s) to article on publisher’s website: http://dx.doi.org/doi:10.18632/oncotarget.1769 Copyright and Moral Rights for the articles on this site are retained by the individual authors and/or other copyright owners. For more information on Open Research Online’s data policy on reuse of materials please consult the policies page. oro.open.ac.uk www.impactjournals.com/oncotarget/ Oncotarget, Vol. 5, No. 3 Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Francesco Crea1, Akira Watahiki1,2, Luca Quagliata3, Hui Xue1, Larissa Pikor4, Abhijit Parolia1,5, Yuwei Wang1, Dong Lin1,2, Wan L. Lam4, William L. Farrar6, Takao Isogai7, Rudolf Morant8, Serenella Castori-Eppenberger3, Kim N. Chi2,9, Yuzhuo Wang1,2, and Cheryl D. Helgason1 1 Experimental Therapeutics, BC Cancer Agency Cancer Research Centre, Vancouver BC, Canada. -
Novel Long Non-Coding Rnas Are Specific Diagnostic and Prognostic Markers for Prostate Cancer
www.impactjournals.com/oncotarget/ Oncotarget, Vol. 6, No.6 Novel long non-coding RNAs are specific diagnostic and prognostic markers for prostate cancer René Böttcher1,3, A. Marije Hoogland2, Natasja Dits1, Esther I. Verhoef2, Charlotte Kweldam2, Piotr Waranecki1, Chris H. Bangma1, Geert J.L.H. van Leenders2, Guido Jenster1 1Dept. of Urology, Erasmus MC, Rotterdam, The Netherlands 2Dept. of Pathology, Erasmus MC, Rotterdam, The Netherlands 3Dept. of Bioinformatics, Technical University of Applied Sciences Wildau, Wildau, Germany Correspondence to: Guido Jenster, e-mail: [email protected] Keywords: Long non-coding RNA, prostate cancer, in situ hybridization, exon array, biomarkers Received: August 22, 2014 Accepted: December 08, 2014 Published: February 17, 2015 ABSTRACT Current prostate cancer (PCa) biomarkers such as PSA are not optimal in distinguishing cancer from benign prostate diseases and predicting disease outcome. To discover additional biomarkers, we investigated PCa-specific expression of novel unannotated transcripts. Using the unique probe design of Affymetrix Human Exon Arrays, we identified 334 candidates (EPCATs), of which 15 were validated by RT-PCR. Combined into a diagnostic panel, 11 EPCATs classified 80% of PCa samples correctly, while maintaining 100% specificity. High specificity was confirmed by in situ hybridization for EPCAT4R966 and EPCAT2F176 (SChLAP1) on extensive tissue microarrays. Besides being diagnostic, EPCAT2F176 and EPCAT4R966 showed significant association with pT-stage and were present in PIN lesions. We also found EPCAT2F176 and EPCAT2R709 to be associated with development of metastases and PCa-related death, and EPCAT2F176 to be enriched in lymph node metastases. Functional significance of expression of 9 EPCATs was investigated by siRNA transfection, revealing that knockdown of 5 different EPCATs impaired growth of LNCaP and 22RV1 PCa cells. -
The Water Beetles of Miller Blue Hole, Sandusky County, Ohio (Insecta: Coleoptera)1-2
THE WATER BEETLES OF MILLER BLUE HOLE, SANDUSKY COUNTY, OHIO (INSECTA: COLEOPTERA)1-2 BRIAN E. MELIN AND ROBERT C. GRAVES Department of Biology, Bowling Green State University, Bowling Green, Ohio 43408 ABSTRACT Thirty-one species of aquatic beetles, representing the families Dytiscidae, Hydro- philidae, Haliplidae, and Gyrinidae, were collected in the Miller Blue Hole, a large spring, between October 21, 1967, and January 27, 1969. The numbers of each species collected are tabulated by monthly intervals. Some of the species present in this unusual habitat are rare; Tropisternus columbianus is apparently recorded from Ohio for the first time. INTRODUCTION The Ohio "blue holes" are the outlets of an extensive underground drainage system occurring in limestone bedrock. They may best be thought of as gigantic springs reaching the surface as deep, conical pools or ponds which are drained by streams flowing into Lake Erie. There are several "blue holes" located in San- dusky and Erie counties, the best known being the Castalia Blue Hole, which has been "developed" as a commercial tourist attraction, with the result that its original natural environment has been destroyed. Closely adjacent to this one is the biggest of the "blue holes," the large spring-fed lake in the center of the town of Castalia. The Miller Blue Hole, six miles to the west of this town, is nearly two acres in size, and has been preserved by the state since 1932 in a relatively natural condi- tion. It is located in a 13-acre wooded tract surrounded by agricultural lands. Earlier works dealing with Miller Blue Hole have only briefly mentioned water beetles. -
Fish Consumption Guidelines: Rivers & Creeks
FRESHWATER FISH CONSUMPTION GUIDELINES: RIVERS & CREEKS NO RESTRICTIONS ONE MEAL PER WEEK ONE MEAL PER MONTH DO NOT EAT NO DATA Bass, LargemouthBass, Other Bass, Shoal Bass, Spotted Bass, Striped Bass, White Bass, Bluegill Bowfin Buffalo Bullhead Carp Catfish, Blue Catfish, Channel Catfish,Flathead Catfish, White Crappie StripedMullet, Perch, Yellow Chain Pickerel, Redbreast Redhorse Redear Sucker Green Sunfish, Sunfish, Other Brown Trout, Rainbow Trout, Alapaha River Alapahoochee River Allatoona Crk. (Cobb Co.) Altamaha River Altamaha River (below US Route 25) Apalachee River Beaver Crk. (Taylor Co.) Brier Crk. (Burke Co.) Canoochee River (Hwy 192 to Lotts Crk.) Canoochee River (Lotts Crk. to Ogeechee River) Casey Canal Chattahoochee River (Helen to Lk. Lanier) (Buford Dam to Morgan Falls Dam) (Morgan Falls Dam to Peachtree Crk.) * (Peachtree Crk. to Pea Crk.) * (Pea Crk. to West Point Lk., below Franklin) * (West Point dam to I-85) (Oliver Dam to Upatoi Crk.) Chattooga River (NE Georgia, Rabun County) Chestatee River (below Tesnatee Riv.) Chickamauga Crk. (West) Cohulla Crk. (Whitfield Co.) Conasauga River (below Stateline) <18" Coosa River <20" 18 –32" (River Mile Zero to Hwy 100, Floyd Co.) ≥20" >32" <18" Coosa River <20" 18 –32" (Hwy 100 to Stateline, Floyd Co.) ≥20" >32" Coosa River (Coosa, Etowah below <20" Thompson-Weinman dam, Oostanaula) ≥20" Coosawattee River (below Carters) Etowah River (Dawson Co.) Etowah River (above Lake Allatoona) Etowah River (below Lake Allatoona dam) Flint River (Spalding/Fayette Cos.) Flint River (Meriwether/Upson/Pike Cos.) Flint River (Taylor Co.) Flint River (Macon/Dooly/Worth/Lee Cos.) <16" Flint River (Dougherty/Baker Mitchell Cos.) 16–30" >30" Gum Crk. -
2011 Regionally Important Resources Plan Regionally Important Resources 2011 1
2011 Regionally Important Resources Plan Regionally Important Resources 2011 1 REGIONALLY IMPORTANT RESOURCES PLAN Southern Georgia July 2011 Prepared by: Valdosta Office 327 West Savannah Avenue Valdosta, GA 31601 Phone: 229.333.5277 Fax: 229.333.5312 Waycross Office 1725 S. GA Parkway, W. Waycross, GA 31503 Phone: 912.285.6097 Fax: 912.285.6126 2 TABLE OF CONTENTS Executive Summary The Purpose The Process The Plan Identification of Resources Introduction Background Designation of Regionally Important Resources Methodology and Process Nomination and Evaluation Research and Data Collection Criteria for Determining Value of RIR Identification of Vulnerability of RIR Stakeholder Review Regionally Important Resources Map Value Matrix Vulnerability Matrix Resource Narrative: Historic & Cultural Resources Resource Narrative: Areas of Conservation & Recreational Value Appendices Appendix A: Stakeholder List Appendix B: Regionally Important Resources Nomination Form Appendix C: List of Regionally Important Resources Appendix D: Regional Resource Plan Briefings and Presentations Appendix E: References 3 Regionally Important Resources Plan EXECUTIVE SUMMARY THE PURPOSE Pursuant to Rules of the Department of Community Affairs, Chapter 110-12-4, Regionally Important Resources are defined as “Any natural or cultural resource area identified for protection by a Regional Commission following the minimum requirements established by the Department.” The Regional Resource Plan is designed to: Enhance the focus on protection and management of important natural and cultural resources in the Southern Georgia Region. Provide for careful consideration of, and planning for, impacts of new development on these important resources. Improve local, regional, and state level coordination in the protection and management of identified resources. THE PROCESS The public nomination process resulted in twenty—one nominations from local governments, non-profit agencies, and private citizens. -
Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications
Stem Cell Rev and Rep DOI 10.1007/s12015-016-9662-8 Detailed Characterization of Human Induced Pluripotent Stem Cells Manufactured for Therapeutic Applications Behnam Ahmadian Baghbaderani 1 & Adhikarla Syama2 & Renuka Sivapatham3 & Ying Pei4 & Odity Mukherjee2 & Thomas Fellner1 & Xianmin Zeng3,4 & Mahendra S. Rao5,6 # The Author(s) 2016. This article is published with open access at Springerlink.com Abstract We have recently described manufacturing of hu- help determine which set of tests will be most useful in mon- man induced pluripotent stem cells (iPSC) master cell banks itoring the cells and establishing criteria for discarding a line. (MCB) generated by a clinically compliant process using cord blood as a starting material (Baghbaderani et al. in Stem Cell Keywords Induced pluripotent stem cells . Embryonic stem Reports, 5(4), 647–659, 2015). In this manuscript, we de- cells . Manufacturing . cGMP . Consent . Markers scribe the detailed characterization of the two iPSC clones generated using this process, including whole genome se- quencing (WGS), microarray, and comparative genomic hy- Introduction bridization (aCGH) single nucleotide polymorphism (SNP) analysis. We compare their profiles with a proposed calibra- Induced pluripotent stem cells (iPSCs) are akin to embryonic tion material and with a reporter subclone and lines made by a stem cells (ESC) [2] in their developmental potential, but dif- similar process from different donors. We believe that iPSCs fer from ESC in the starting cell used and the requirement of a are likely to be used to make multiple clinical products. We set of proteins to induce pluripotency [3]. Although function- further believe that the lines used as input material will be used ally identical, iPSCs may differ from ESC in subtle ways, at different sites and, given their immortal status, will be used including in their epigenetic profile, exposure to the environ- for many years or even decades. -
Alapahoochee River Watershed R Watershed Restoration Action Strategy R November 2007 ( R
( Alapahoochee River Watershed r Watershed Restoration Action Strategy r November 2007 ( r Compiled by: South Georgia Regional Development Center Mission: To improve watershed health and water quality based upon best management practices, by identifying objectives and goals that are feasible, attainable, and beneficial to the stakeholders. THE PREPARATION OF THIS DOCUMENT WAS FINANCED IN PART THROUGH A GRANT FROM THE U.S. ENVIRONMENTAL PROTECTION AGENCY UNDER THE PROVISIONS OF SECTION 319 OF THE FEDERAL WATER POLLUTION CONTROL ACT. ( Table of Contents for WRAS Acknowledgement ............................................................................................................................... 1 Acronyms ............................................................................................................................................ 3 Glossary .............................................................................................................................................. 4 Executive Summary ............................................................................................................................ 7 Chapter 1: Introduction 1.1 Background Information .............................................................................................................. 8 1.2 Purpose of a WRAS ..................................................................................................................... 9 1.3 EPA's Nine Key Elements .........................................................................................................