DOCSLIB.ORG

Differential Diagnosis of the Swollen Red Eyelid ART PAPIER, MD; DAVID J

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Differential Diagnosis of the Swollen Red Eyelid ART PAPIER, MD; DAVID J Differential Diagnosis of the Swollen Red Eyelid ART PAPIER, MD; DAVID J. TUTTLE, MD; and TARA J. MAHAR, MD University of Rochester School of Medicine and Dentistry, Rochester, New York The differential diagnosis of eyelid erythema and edema is broad, ranging from benign, self- limiting dermatoses to malignant tumors and vision-threatening infections. A definitive diagnosis usually can be made on physical examination of the eyelid and a careful evalu- ation of symptoms and exposures. The finding of a swollen red eyelid often signals celluli- tis. Orbital cellulitis is a severe infection presenting with proptosis and ophthalmoplegia; it requires hospitalization and intravenous antibiotics to prevent vision loss. Less serious conditions, such as contact dermatitis, atopic dermatitis, and blepharitis, are more common causes of eyelid erythema and edema. These less serious conditions can often be managed with topical corticosteroids and proper eyelid hygiene. They are differentiated on the basis of such clinical clues as time course, presence or absence of irritative symptoms, scaling, and other skin findings. Discrete lid lesions are also important diagnostic indicators. The finding of vesicles, erosions, or crusting may signal a herpes infection. Benign, self-limited eyelid nodules such as hordeola and chalazia often respond to warm compresses, whereas malignancies require surgical excision. (Am Fam Physician 2007;76:1815-24. Copyright © 2007 American Academy of Family Physicians.) ▲ Patient information: atients with eyelid erythema and Contact dermatitis can be classified as A handout on herpes zos- edema often present first to the allergic or irritant. The presenting features of ter ophthalmicus is avail- able at http://familydoctor. family physician. Cellulitis may be these types often are not readily distinguish- org/745.xml. suspected in patients with a red, able, but patients with irritant contact der- P swollen eyelid, although dermatitis is a more matitis often present with greater burning common cause. The differential diagnosis of and stinging compared with the characteris- eyelid edema is extensive, but knowledge of tic pruritus of allergic contact dermatitis.1,7,8 the key features of several potential causes can assist physicians in diagnosing this con- ETIOLOGY dition (Table 1). Particular attention must Contact dermatitis of the eyelid is medi- be paid to visual clues, exposures, and other ated by a type IV hypersensitivity reaction historical factors in the work-up of patients in allergic contact dermatitis and by direct with eyelid edema (Figure 11,2). toxic effect in irritant contact dermatitis.1 It is more often caused by a product applied Contact Dermatitis to the hair, nails, or face than by products Contact dermatitis is the most common applied directly to the eyelids.7 Table 2 lists cause of cutaneous eyelid inflammation.3-6 common exposures that can cause contact Eyelid skin is especially vulnerable to irri- dermatitis.8-23 tants and allergens because of its thinness and frequent exposure to chemicals via DIAGNOSIS direct application or contamination from A careful history of exposure to agents known fingers and hands.3,7 As one of the most sen- to cause eyelid contact dermatitis should be sitive areas, eyelid skin may be the initial or elicited. The patient should be asked about only presenting area with signs of contact his or her occupation, hobbies, and cosmetic dermatitis, while other areas of the body use (including non-eye cosmetics, new prod- remain unaffected by the same exposure.7 ucts, and refills of a previously used product, Downloaded from the American Family Physician Web site at www.aafp.org/afp. Copyright © 2007 American Academy of Family Physicians. For the private, noncommercial use of one individual user of the Web site. All other rights reserved. Contact [email protected] for copyright questions and/or permission requests. Swollen Red Eyelid Table 1. Causes of Eyelid Erythema and Edema: Distinguishing Features and Treatments Condition Signs and symptoms Treatment Conditions typically presenting bilaterally Angioedema Often, but not always bilateral Often self-limited; avoid inciting agents Abrupt onset over minutes to hours; Emergency medical attention is required in patients with upper airway may follow an exposure obstruction; administer 0.3 mg of intramuscular epinephrine Scaling usually absent Mild cases may benefit from oral antihistamines and/or glucocorticoids: Diphenhydramine hydrochloride (Benadryl), 25 to 50 mg three or four times daily (dosage for children: 4 to 6 mg per kg per day, in three or four divided doses) Loratadine (Claritin), 10 mg daily (dosage for children two to five years of age: 5 mg daily) Prednisone, 0.5 to 1.0 mg per kg per day, then taper after three or four days Atopic Fine scaling usually present Oral antihistamines (see above) dermatitis Less edema than with contact Topical corticosteroids: dermatitis Desonide (Tridesilon) 0.05% Other signs of atopic dermatitis may Alclometasone dipropionate (Aclovate) 0.05% twice daily for five to be present 10 days Family or personal history of allergic Second-line treatments: rhinitis or atopic dermatitis Tacrolimus (Protopic) 0.1% ointment twice daily Pimecrolimus (Elidel) 1% cream twice daily Blepharitis Yellow scaling at eyelid margins Local measures: eyelid massage, warm compresses, and gentle Patients may have pruritus or burning scrubbing twice daily with a cotton swab and 1:1 solution of dilute Less edema than with cellulitis or baby shampoo or commercially available eyelid cleanser contact dermatitis; edema more For staphylococcal infections, bacitracin or erythromycin ointment to prominent at eyelid margin eyelid margins at bedtime for one to two weeks For meibomian gland dysfunction, may add tetracycline, 250 mg four times daily, or doxycycline (Vibramycin), 100 mg three times daily, then taper after four weeks Contact Onset follows exposure Avoid inciting agents dermatitis Pruritus in allergic contact dermatitis; For allergic dermatitis, desonide 0.05% or alclometasone dipropionate burning or stinging in irritant 0.05% cream or ointment twice daily for five to 10 days contact dermatitis For irritant dermatitis, cool compresses and a petroleum-based Minimal scaling emollient applied at bedtime Edema may be profound Rosacea Telangiectasias often present Local measures as for blepharitis Onset over weeks to months Systemic tetracyclines: Eyelid changes often accompany Tetracycline, 250 mg four times daily flushing, papules, and pustules of Doxycycline, 100 mg three times daily the nose, cheek, forehead, and chin Topical metronidazole 0.75% cream (Metrocream) or gel (Metrogel) twice daily Azelaic acid gel (Finacea) twice daily Systemic Onset over weeks to months Maximize treatment of the underlying disorder processes Other cutaneous and systemic findings present continued because changes in cosmetic formulations with or without involvement of the face and are common).7 Patients with irritant contact hands.1 Examination may reveal a combina- dermatitis may have pruritus, burning, or tion of erythema, edema, and vesiculation in stinging of the eyelids and periorbital area, patients with acute dermatitis, or scaling and 1816 American Family Physician www.aafp.org/afp Volume 76, Number 12 ◆ December 15, 2007 Swollen Red Eyelid Table 1 (continued) Condition Signs and symptoms Treatment Conditions typically presenting unilaterally Cellulitis* Often presents with severe edema, deep Suggested oral regimen for patients with preseptal cellulitis only†: violaceous color, and pain Amoxicillin/clavulanate (Augmentin), 875 mg twice daily or Onset over hours to days 500 mg three times daily (dosage for children older than three History of preceding trauma or bite months: 40 mg per kg three times daily; dosage for children younger than three months: 30 mg per kg every 12 hours) Suggested intravenous regimens: Ampicillin/sulbactam (Unasyn), 1.5 to 3 g every six hours (dosage for children: 300 mg per kg daily, divided every six hours) Ceftriaxone (Rocephin), 1 to 2 g daily or divided every 12 hours (dosage for children: 50 to 75 mg per kg daily, divided every 12 hours) Parenteral antibiotics are often given for seven days in orbital cellulitis; transition to oral antibiotics if clinical improvement is noted after one week, to complete a total treatment course of 21 days Herpes simplex Vesicles often present Often self-limited; use supportive measures such as compresses Pain or burning may be present Topical bacitracin may help prevent secondary infection Onset over hours to days Recurrent cases can be treated with long-term suppressive therapy: Acyclovir (Zovirax), 400 mg twice daily Valacyclovir (Valtrex), 500 mg to 1,000 mg daily Famciclovir (Famvir), 250 mg twice daily Herpes zoster Older adults Cool compresses ophthalmicus Vesicles often present Acyclovir, 800 mg five times daily for seven to 10 days; Pain or burning valacyclovir, 1 g three times daily for seven days; or Onset over hours to days famciclovir, 500 mg three times daily for seven days Early initiation of tricyclic antidepressants (desipramine [Norpramin], 25 to 75 mg at bedtime) may inhibit postherpetic neuralgia Patients may require additional treatment for complications such as keratitis and glaucoma Tumors Older adults Depending on tumor type, Mohs micrographic surgery or wide Insidious onset local excision Typically painless nodule *—Alternative empiric regimens may be necessary in patients with community-acquired methicillin-resistant Staphylococcus
Load more

Recommended publications
  • Eyelid and Orbital Infections
    27 Eyelid and Orbital Infections Ayub Hakim Department of Ophthalmology, Western Galilee - Nahariya Medical Center, Nahariya, Israel 1. Introduction The major infections of the ocular adnexal and orbital tissues are preseptal cellulitis and orbital cellulitis. They occur more frequently in children than in adults. In Schramm's series of 303 cases of orbital cellulitis, 68% of the patients were younger than 9 years old and only 17% were older than 15 years old. Orbital cellulitis is less common, but more serious than preseptal. Both conditions happen more commonly in the winter months when the incidence of paranasal sinus infections is increased. There are specific causes for each of these types of cellulitis, and each may be associated with serious complications, including vision loss, intracranial infection and death. Studies of orbital cellulitis and its complication report mortality in 1- 2% and vision loss in 3-11%. In contrast, mortality and vision loss are extremely rare in preseptal cellulitis. 1.1 Definitions Preseptal and orbital cellulites are the most common causes of acute orbital inflammation. Preseptal cellulitis is an infection of the soft tissue of the eyelids and periocular region that is localized anterior to the orbital septum outside the bony orbit. Orbital cellulitis ( 3.5 per 100,00 ) is an infection of the soft tissues of the orbit that is localized posterior to the orbital septum and involves the fat and muscles contained within the bony orbit. Both types are normally distinguished clinically by anatomic location. 1.2 Pathophysiology The soft tissues of the eyelids, adnexa and orbit are sterile. Infection usually originates from adjacent non-sterile sites but may also expand hematogenously from distant infected sites when septicemia occurs.
    [Show full text]
  • Clinical Characteristics and Outcomes of Paediatric Orbital Cellulitis in Hospital Universiti Sains Malaysia: a Five-Year Review
    Singapore Med J 2020; 61(6): 312-319 Original Article https://doi.org/10.11622/smedj.2019121 Clinical characteristics and outcomes of paediatric orbital cellulitis in Hospital Universiti Sains Malaysia: a five-year review Ismail Mohd-Ilham1,2, MBBS, MMed, Abd Bari Muhd-Syafi1,2, MBBS, Sonny Teo Khairy-Shamel1,2, MD, MMed, Ismail Shatriah1,2, MD, MMed INTRODUCTION Limited data is available on paediatric orbital cellulitis in Asia. We aimed to describe demographic data, clinical presentation, predisposing factors, identified microorganisms, choice of antibiotics and management in children with orbital cellulitis treated in a tertiary care centre in Malaysia. METHODS A retrospective review was performed on children with orbital cellulitis aged below 18 years who were admitted to Hospital Universiti Sains Malaysia, Kelantan, Malaysia, between January 2013 and December 2017. RESULTS A total of 14 paediatric patients fulfilling the diagnostic criteria for orbital cellulitis were included. Their mean age was 6.5 ± 1.2 years. Boys were more likely to have orbital cellulitis than girls (71.4% vs. 28.6%). Involvement of both eyes was observed in 14.3% of the patients. Sinusitis (28.6%) and upper respiratory tract infection (21.4%) were the most common predisposing causes. Staphylococcus aureus (28.6%) was the leading pathogen. Longer duration of hospitalisation was observed in those infected with methicillin-resistant Staphylococcus aureus and Burkholderia pseudomallei. 10 (71.4%) patients were treated with a combination of two or three antibiotics. In this series, 42.9% had surgical interventions. CONCLUSION Young boys were found to be more commonly affected by orbital cellulitis than young girls.
    [Show full text]
  • Preseptal and Orbital Cellulitis
    Journal of Microbiology and Infectious Diseases / 2014; 4 (3): 123-127 JMID doi: 10.5799/ahinjs.02.2014.03.0154 REVIEW ARTICLE Preseptal and orbital cellulitis Emine Akçay, Gamze Dereli Can, Nurullah Çağıl Yıldırım Beyazıt Univ. Medical Faculty Atatürk Training and Research Hospital Dept. of Ophthalmology, Ankara, Turkey ABSTRACT Preseptal cellulitis (PC) is defined as an inflammation of the eyelid and surrounding skin, whereas orbital cellulitis (OC) is an inflammation of the posterior septum of the eyelid affecting the orbit and its contents. Periorbital tissues may become infected as a result of trauma (including insect bites) or primary bacteremia. Orbital cellulitis generally occurs as a complication of sinusitis. The most commonly isolated organisms are Staphylococcus aureus, Streptococcus pneu- moniae, S. epidermidis, Haempphilus influenzae, Moraxella catarrhalis and S. pyogenes. The method for the diagnosis of OS and PS is computed tomography. Using effective antibiotics is a mainstay for the treatment of PC and OC. There is an agreement that surgical drainage should be performed in cases of complete ophthalmoplegia or significant visual impairment or large abscesses formation. This infections are also at a greater risk of acute visual loss, cavernous sinus thrombosis, meningitis, cerebritis, endo- phthalmitis, and brain abscess in children. Early diagnosis and appropriate treatment are crucial to control the infection. Diagnosis, treatment, management and complications of PC and OC are summarized in this manuscript. J Microbiol Infect Dis 2014; 4(3): 123-127 Key words: infection, cellulitis, orbita, preseptal, diagnosis, treatment Preseptal ve Orbital Sellülit ÖZET Preseptal selülit (PS) göz kapağı ve çevresindeki dokunun iltihabi reaksiyonu iken orbital selülit (OS) orbitayı ve onun içeriğini etkileyen septum arkası dokuların iltihabıdır.
    [Show full text]
  • Peri-Orbital and Orbital Cellulitis
    Peri-Orbital and Orbital Cellulitis Reference: 1694 Written by: Judith Gilchrist Peer reviewer: Lucy Hinds Approved: November 2017 Review Due: September 2021 Purpose To guide the management of periorbital and orbital cellulitis Intended Audience Clinical staff managing the patient Author: Judith Gilchrist Review date: September 2021 © SC(NHS)FT 2017. Not for use outside the Trust. Page 1 of 3 CAEC Registration Identifier: 1694 Sheffield Children’s (NHS) Foundation Trust Peri-Orbital and Orbital Cellulitis Table of Contents 1. Introduction 2. Guideline Content A. Pre-septal Cellulitis B. Orbital Cellulitis 3. References 1. Introduction Pre–septal (periorbital) cellulitis is a common condition and the majority of cases can be managed on oral antibiotics and discharged home. Orbital cellulitis is however a serious condition with significant long term morbidity and requires aggressive management. Differentiating between the two conditions is important but fortunately relatively simple. 2. Intended Audience Clinical staff managing the patient 3. Guideline Content A. PRE-SEPTAL CELLULITIS Symptoms include lid swelling and redness. Signs include lid swelling and erythema but otherwise normal eye examination. Take history and perform basic eye examination – remember to check visual acuity, pupils and eye movements. Management If under 3 months old - admit under medics and refer to ophthalmology and ENT. If over 3 months old – If systemically well, sensible parents and mild features may be discharged on PO antibiotics (co-amoxiclav). Author: Judith Gilchrist Review date: September 2021 © SC(NHS)FT 2017. Not for use outside the Trust. Page 2 of 3 CAEC Registration Identifier: 1694 Sheffield Children’s (NHS) Foundation Trust Peri-Orbital and Orbital Cellulitis Mild features include - Lids can be opened, the eye itself is not red, eye movements and visual acuity are normal and none of the symptoms or signs of orbital cellulitis below are present.
    [Show full text]
  • Periorbital and Orbital Cellulitis
    JAMA PATIENT PAGE Periorbital and Orbital Cellulitis Periorbital cellulitis is an infection of the eyelid and area around the eye; orbital cellulitis is an infection of the eyeball and tissues around it. Periorbital and orbital cellulitis are infections that most often Periorbital and orbital cellulitis are infections that affect tissues occur in young children. The septum is a membrane that sepa- of the eye in front of and behind the orbital septum. rates the front part of the eye from the back part of the eye. Peri- Periorbital cellulitis affects the skin Orbital cellulitis affects deeper orbital cellulitis is also called preseptal cellulitis because it affects and soft tissue in front of the septum. tissues behind the septum. the structures in front of the septum, such as the eyelid and skin around the eye. Orbital cellulitis involves the eyeball itself, the fat around it, and the nerves that go to the eye. Both of these infec- tions can be caused by bacteria that normally live on the skin or by other bacteria. Symptoms and Causes Orbital septum Orbital septum Periorbital cellulitis often occurs from a scratch or insect bite around Both infections can present with swelling, redness, fever, or pain, but have specific the eye that leads to infection of the skin. Symptoms can include characteristics that can be used to tell them apart along with imaging. swelling, redness, pain, and tenderness to touch occurring around Specific to periorbital cellulitis Specific to orbital cellulitis No pain with movement of eye Pain with movement of eye one eye only. The affected person is able to move the eye in all di- Vision is normal Double vision or blurry vision rections without pain, but there can be difficulty opening the eye- Proptosis (bulging of the eye) lid, often due to swelling.
    [Show full text]
  • EML Application on Eye Infections
    EML Application on eye infections Applicants: Dr. Mark Loeb, Dr. Dominik Mertz McMaster University Correspondence: Dr. Mark Loeb, McMaster University, 1280 Main St West, MDCL 3200, Hamilton, Ontario, Canada L8S 4K1; [email protected] 1 Background The WHO Essential Medicine List (EML) lists the most efficacious and safe medicines to treat illnesses that are considered high priority, including antibiotics. However, most antibiotics were listed decades ago and a comprehensive review of all the antibiotics listed over the past 40 years has never been done. Given increasing concerns about overuse of antibiotics, the emergence of antimicrobial resistance and the need to guarantee prompt access to highly beneficial treatments, revising and updating the list is an important priority. Applications for revisions to the Model List are accepted every 2 years and are by single agent. However, similarly to what has been done for cancer in 2015, a syndrome-based approach was agreed as the best option. We have revised the list based on common syndromes to date and have now done this for eye infections. All potentially relevant antibiotics for use across low, middle and high-income countries, were considered. The working group and the EML Secretariat a priori reasoned on the guiding principles to prioritize the selection of antibiotics: safety and efficacy, resistance, feasibility, parsimony. As in our previous work on the original 21 syndromes [1], this review of the evidence was supplemented by a systematic search and synthesis of clinical practice guidelines. We placed a relative high value on evidence and guideline recommendations that can be applicable to a majority of patients and settings.
    [Show full text]
  • Periorbital Edema Script
    PedsCases Podcast Scripts This is a text version of a podcast from Pedscases.com on “Approach to Pediatric Periorbital Edema.” These podcasts are designed to give medical students an overview of key topics in pediatrics. The audio versions are accessible on iTunes or at www.pedcases.com/podcasts. Approach to Pediatric Periorbital Edema Developed by Monique Jarrett, Dr. Melanie Lewis, and Dr. Catherine Morgan for PedsCases.com. Jul 13, 2017 Introduction: Hello, my name is Monique Jarrett. I am a second year medical student at the University of Alberta. This podcast was developed with the help of Dr. Melanie Lewis a Pediatrician and Professor at the University of Alberta and Dr. Catherine Morgan a Pediatric Nephrologist and Associate Professor at the University of Alberta. This podcast will help you develop an approach to a child presenting with periorbital edema. Objectives ● Determine the key differential diagnoses for the presentation of periorbital edema ● Identify historical aspects, physical exam findings and diagnostic studies that can help determine the etiology of the periorbital edema ● Discuss the key points on history and physical exam that differentiate periorbital cellulitis from orbital cellulitis ● Outline the management of periorbital cellulitis and orbital cellulitis Cases Case 1: A 5-year old boy presents with rapid onset bilateral eye swelling. He has had no changes in the quality of his vision. His history includes a recent upper respiratory tract infection 2 weeks ago. Case 2: A 13-year-old boy presents to the emergency department with his left eye swollen shut. He came in straight from his baseball tournament. Upon examination, there were no changes in the quality of his vision.
    [Show full text]
  • Ophthalmic Manifestations of Acute Leukaemias T Sharma Et Al 664
    Eye (2004) 18, 663–672 & 2004 Nature Publishing Group All rights reserved 0950-222X/04 $30.00 www.nature.com/eye 1 1 2 1 Ophthalmic T Sharma , J Grewal , S Gupta and PI Murray REVIEW manifestations of acute leukaemias: the ophthalmologist’s role Abstract neoplastic cells. Ophthalmic involvement can be classified into two major categories: (1) primary With evolving diagnostic and therapeutic or direct leukaemic infiltration, (2) secondary or advances, the survival of patients with acute indirect involvement. The direct leukaemic leukaemia has considerably improved. This infiltration can show three patterns: anterior has led to an increase in the variability of segment uveal infiltration, orbital infiltration, ocular presentations in the form of side effects and neuro-ophthalmic signs of central nervous of the treatment and the ways leukaemic system leukaemia that include optic nerve relapses are being first identified as an ocular infiltration, cranial nerve palsies, and presentation. Leukaemia may involve many papilloedema. The secondary changes are the ocular tissues either by direct infiltration, result of haematological abnormalities of haemorrhage, ischaemia, or toxicity due to leukaemia such as anaemia, thrombocytopenia, various chemotherapeutic agents. Ocular hyperviscosity, and immunosuppression. These involvement may also be seen in graft-versus- can manifest as retinal or vitreous haemorrhage, host reaction in patients undergoing infections, and as vascular occlusions. In some allogeneic bone marrow transplantation, or cases the ocular involvement may be simply as increased susceptibility to infections asymptomatic. In one prospective study, there as a result of immunosuppression that these was a high prevalence of asymptomatic ocular 1 patients undergo. This can range from simple Birmingham and Midland lesions in childhood acute leukaemia.1 In the era bacterial conjunctivitis to an endophthalmitis.
    [Show full text]
  • Recurrent Lacrimal Abscess in Infant
    CASE REPORT ASIAN JOURNAL OF MEDICAL SCIENCES Recurrent lacrimal abscess in infant Monojit Mondal1, Biswajit Biswas2, Sumanta Laha2, Atanu Roy2, Kanai Lal Barik3, Asok Kumar Datta4, Sayan Bose1, Tanmoy Biswas1 1Resident, Department of Pediatric Medicine, Burdwan Medical College and Hospital, Burdwan, India, 2Assistant Professor, Department of Pediatric Medicine, Burdwan Medical College and Hospital, Burdwan, India, 3Professor, Department of Pediatric Medicine, Burdwan Medical College and Hospital, Burdwan, India, 4Professor and Head, Department of Pediatric Medicine, Burdwan Medical College and Hospital, Burdwan, India Submitted: 20-05-2014 Revised: 25-08-2014 Published: 31-10-2014 ABSTRACT Acute dacryocystitis at or shortly after birth is uncommon and its main complication, formation Access this article online of lacrimal sac abscess, is rare. Uniform and standard treatment protocol for this condition Website: has not been established till date. We report on a 2 month old infant with an abscess of the lacrimal sac. He was treated for similar condition on day 6 of his life by incision and http://nepjol.info/index.php/AJMS drainage; unfortunately, the condition recurs. This time, he was managed with incision and DOI: 10.3126/ajms.v6i2.10458 drainage under systemic antibiotic cover; and an early probing of the nasolacrimal duct (NLD) was done on 7th post-operative day. The patient was followed up for a period of one year without any further recurrence and complication. Pathophysiology of the condition and possible treatment options in children have been discussed. Key words: Lacrimal abscess, Acute dacryocystitis, Infancy, Recurrence INTRODUCTION the history that baby was treated by incision and drainage and some oral medicines for a painful abscess at the inner Acute dacryocystitis, or infl ammation of the lacrimal sac aspect of the right eye on day 6 of life.
    [Show full text]
  • Guide Cellulite Adulte WEB EN.Pdf
    OCTOBER 2017 DRUG ANTIBIOTICS CELLULITIS IN ADULTS This optimal usage guide is mainly intended for primary care health professionnals. It is provided for information purposes only and should not replace the clinician’s judgement. The recommendations were developed using a systematic approach and are supported by the scientific literature and the knowledge and experience of Quebec clinicians and experts. For more details, go to inesss.qc.ca. GENERAL INFORMATION IMPORTANT CONSIDERATIONS Cellulitis can be observed on all skin surfaces, but most cases are found on the legs. CELLULITIS IN ADULTS Cellulitis is typically caused by β-hemolytic streptococci or Staphylococcus aureus, although a pathogen is isolated in less than 20 % of cases. Differential diagnosis is a major issue, since some skin conditions – that do not require antibiotic therapy – can present similar symptoms/signs. RISK FACTORS FOR DEVELOPING CELLULITIS Portal of entry or potential reservoir Comorbidities and other factors • Injury • Venous or arterial insufficiency • Skin problem (e.g., eczema) • Lymphedema • Toe web abnormalities (e.g., tinea pedis) • Uncontrolled diabetes • Hygiene or neglect issues • Immunosuppression • Uncorrected dental problem • History of cellulitis DIAGNOSIS SIGNS AND SYMPTOMS Photos available to help with diagnosis Cellulitis diagnosis is generally characterized by the acute appearance of a continuous erythematous area (without an area of healthy skin inside) that’s edematous, warm and painful. The patient may also have systemic symptoms (fever, nausea, vomiting, chills, malaise, lack of appetite). Cellulitis generally does not cause any epidermal changes (scales, scabs, vesicles, etc.). If such changes are present, suspect a different or related pathology (e.g., eczema). CLINICAL ASSESSMENT Assess the general condition of the patient.
    [Show full text]
  • Cellulitis Ophthalmic Signs Most Frequently Seen with Orbital Cellulitis Are Limited Ocular Motility, Proptosis, Chemosis, and Conjunctival Hyperemia (See Figure 4)
    Orbital Cellulitis Ophthalmic signs most frequently seen with orbital cellulitis are limited ocular motility, proptosis, chemosis, and conjunctival hyperemia (see Figure 4). Fever and leukocytosis are also suggestive of an orbital infection. Vision loss and an afferent pupillary defect may occur due to severe orbital congestion and optic nerve involvement. Exposure keratopathy may also contribute to diminished vision because of disruption of corneal integrity, microbial keratitis, and stromal opacification. Delayed management may result in significant morbidity, including orbital apex syndrome (internal and external ophthalmoplegia, blepharoptosis, diminished corneal sensation, and vision loss) and blindness. Cavernous sinus thrombosis, cranial nerve palsies, meningitis, intracranial abscess formation, and even death can occur without prompt aggressive treatment. Etiology As with preseptal cellulitis, infectious orbital cellulitis generally occurs by extension of sinus disease, penetrating trauma, or from infected adjacent structures. Underlying ocular infections—including those associated with aqueous drainage device procedures, scleral buckles, or fulminant endophthalmitis—are less common causes of orbital cellulitis. Orbital infections may have an odontogenic origin, including severe dental caries or a recent dental procedure. Orbital cellulitis secondary to hematogenous dissemination has been reported, particularly in newborns. In addition to the most common infectious causes of periorbital cellulitis reviewed in this module, a host
    [Show full text]
  • Periorbital Dermatology
    Periorbital Dermatology Michelle Tarbox 02/28/2020 Periorbital skin • Characteristics of periorbital skin – Delicate and thin – More susceptible to irritation and allergy – Easily shows changes due to sun, age and irritation Roadmap • Periocular Dermatitis • Periorbital Manifestations of Connective Tissue Disease • Periorbital Manifestations of Systemic Diseases • Periorbital Infections • Periorbital rejuvenation Periocular Dermatitis • Periocular contact dermatitis (54% of cases) – Direct allergic contact (44%) – Airborne allergic contact dermatitis (10%) • Periocular atopic dermatitis (25%) • Periocular irritant contact dermatitis (9%) • Periorificial dermatitis (4.5%) • Periorbital psoriasis (2%) • Periorbital allergic conjunctivitis (2%) Feser A, . Mahler V. Periobital dermatitis – a recalcitrant disease: Causes and differential diagnosis. Br J Dermatol 2008; 159:858-63. Periorbital Contact Dermatitis Periorbital Contact Dermatitis • Inflammatory reaction of the eyelid skin • Scaling, swelling, erythema, itching • Upper and/or lower eyelids on one or both sides can be affected • Contact with a trigger substance • Allergy – allergic contact dermatitis – Nickel, fragrance mix, balsam of Peru, preservatives, Nail polish (toluene), hair dye, eye cream, shampoo – Patch testing for confirmation Periorbital Contact Dermatitis • Evaluation – Patch testing – Elimination challenge – very simple skincare regimen for at least a month • Therapy – Topical corticosteroids • Caution near eye to avoid development of cataracts and thinning of sin –
    [Show full text]