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Organic KSM-66 Ashwagandha Organic KSM-66 Ashwagandha Cambridge Commodities Chemwatch Hazard Alert Code: 2 Part Number: P11206 Issue Date: 19/08/2021 Version No: 1.1.23.11 Print Date: 24/09/2021 Safety data sheet according to REACH Regulation (EC) No 1907/2006, as amended by UK REACH Regulations SI 2019/758 S.REACH.GB.EN SECTION 1 Identification of the substance / mixture and of the company / undertaking 1.1. Product Identifier Product name Organic KSM-66 Ashwagandha Chemical Name Withania somnifera (ashwagandha) extract Synonyms Not Available Chemical formula Not Applicable Other means of P11206 identification 1.2. Relevant identified uses of the substance or mixture and uses advised against Tropane alkaloids (syn: belladonna alkaloids, bicyclic alkaloids) have pharmacological properties and can acts as anticholinergics (blocking involuntary movements of smooth muscle) or stimulants. Herbal medicines containing tropane alkaloids have been used to treat asthma, chronic bronchitis, pain, and flu symptoms. Most tropane alkaloids may be unscheduled in certain jurisdictions but possession may potentially be prosecuted under the certain "Analog Acts". Tropanes which do appear in various schedules include, atropine, cocaine and belladonna (a hallucinogenic deliriant). These substances contain the nitrogenous bicyclic alkaloid parent N-methyl-8-azabicyclo[3.2.1]octane. Tropane alkaloids occur in plants of the families Erythroxylaceae (including coca) and Solanaceae (including mandrake, henbane, deadly nightshade, datura, potato, tomato). All of these plants have long histories of hallucinogenic use and have been connected with sorcery, witchcraft, native medicine, and magico-religious rites.Many cultures worldwide add plants with tropane alkaloids (particularly Datura species) to alcoholic beverages to increase intoxication. Extracts of Solanacea (derived, for example, from jimson weed, black henbane and mandrake) were used in Europe in the Middle Ages preparations produced by witches - these were applied as ointments to the mucous membranes of the genital Relevant identified uses organs to produce ecstasy and erotic feelings. The Aztecs worshipped jimson weed and used it for cult purposes and for punishment. Solanacea plants have been used in human poisonings. Therapeutic or pharmacologically-active agent. Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications. Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pylorospasm, diverticulitis, ulcerative colitis, nausea, and vomiting) Genitourinary disorders (e.g., cystitis, urethritis, and prostatitis) Insomnia, although usually only on a short-term basis Respiratory disorders (e.g., asthma, chronic bronchitis, and chronic obstructive pulmonary disease [COPD]) Sinus bradycardia due to a hypersensitive vagus nerve Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, Product code: P11206 Version No: 1.1.23.2 Page 1 of 21 S.REACH.GB.EN Lancaster Way Business Park Safety Data Sheet (Conforms to Regulation (EU) No 2020/878) Ely, Cambridgeshire, CB6 3NX, UK. Chemwatch: 9-847248 +44 (0) 1353 667258 Issue Date: 19/08/2021 [email protected] Print Date: 24/09/2021 www.c-c-l.com both being advantageous in surgical procedures. An anticholinergic agent is a substance that blocks the action of the neurotransmitter acetylcholine at synapses in the central and the peripheral nervous system. These agents inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movement of smooth muscles present in the gastrointestinal tract, urinary tract, lungs, and many other parts of the body. Anticholinergics are divided into three categories in accordance with their specific targets in the central and peripheral nervous system: antimuscarinic agents, ganglionic blockers, and neuromuscular blockers. Uses advised against Not Applicable 1.3. Details of the supplier of the safety data sheet Registered company name Cambridge Commodities Address Lancaster Way Business Park, Ely, Cambridgeshire Cambridgeshire CB6 3NX United Kingdom Telephone +44 1353 667258 Fax Not Available Website Not Available Email [email protected] 1.4. Emergency telephone number Association / Organisation Not Available Emergency telephone Not Available numbers Other emergency Not Available telephone numbers SECTION 2 Hazards identification 2.1. Classification of the substance or mixture Classified according to GB-CLP Regulation, UK SI H302 - Acute Toxicity (Oral) Category 4, H317 - Sensitisation (Skin) Category 1 2019/720 and UK SI 2020/1567 [1] Legend: 1. Classified by Chemwatch; 2. Classification drawn from GB-CLP Regulation, UK SI 2019/720 and UK SI 2020/1567 2.2. Label elements Hazard pictogram(s) Signal word Warning Hazard statement(s) H302 Harmful if swallowed. Product code: P11206 Version No: 1.1.23.2 Page 2 of 21 S.REACH.GB.EN Lancaster Way Business Park Safety Data Sheet (Conforms to Regulation (EU) No 2020/878) Ely, Cambridgeshire, CB6 3NX, UK. Chemwatch: 9-847248 +44 (0) 1353 667258 Issue Date: 19/08/2021 [email protected] Print Date: 24/09/2021 www.c-c-l.com H317 May cause an allergic skin reaction. Supplementary statement(s) Not Applicable Precautionary statement(s) Prevention P280 Wear protective gloves and protective clothing. P261 Avoid breathing dust/fumes. P264 Wash all exposed external body areas thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P272 Contaminated work clothing should not be allowed out of the workplace. Precautionary statement(s) Response P302+P352 IF ON SKIN: Wash with plenty of water. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/physician/first aider if you feel unwell. P330 Rinse mouth. Precautionary statement(s) Storage Not Applicable Precautionary statement(s) Disposal P501 Dispose of contents/container to authorised hazardous or special waste collection point in accordance with any local regulation. 2.3. Other hazards REACh - Art.57-59: The mixture does not contain Substances of Very High Concern (SVHC) at the SDS print date. SECTION 3 Composition / information on ingredients 3.1.Substances See 'Composition on ingredients' in Section 3.2 3.2.Mixtures 1.CAS No 2.EC No Classified according to GB-CLP Regulation, Nanoform Particle %[weight] Name 3.Index No UK SI 2019/720 and UK SI 2020/1567 Characteristics 4.REACH No 1.90147-43-6 2.290-434-9 Withania somnifera Acute Toxicity (Oral) Category 4, Sensitisation 100 Not Available 3.Not Available (ashwagandha) extract (Skin) Category 1; H302, H317 [1] 4.Not Available Legend: 1. Classified by Chemwatch; 2. Classification drawn from GB-CLP Regulation, UK SI 2019/720 and UK SI 2020/1567; 3. Classification drawn from C&L; * EU IOELVs available; [e] Substance identified as having endocrine disrupting properties Product code: P11206 Version No: 1.1.23.2 Page 3 of 21 S.REACH.GB.EN Lancaster Way Business Park Safety Data Sheet (Conforms to Regulation (EU) No 2020/878) Ely, Cambridgeshire, CB6 3NX, UK. Chemwatch: 9-847248 +44 (0) 1353 667258 Issue Date: 19/08/2021 [email protected] Print Date: 24/09/2021 www.c-c-l.com SECTION 4 First aid measures 4.1. Description of first aid measures If this product comes in contact with the eyes: Wash out immediately with fresh running water. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally Eye Contact lifting the upper and lower lids. Seek medical attention without delay; if pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. If skin contact occurs: Immediately remove all contaminated clothing, including footwear. Skin Contact Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation. If fumes, aerosols or combustion products are inhaled remove from contaminated area. Inhalation Other measures are usually unnecessary. IF SWALLOWED, REFER FOR MEDICAL ATTENTION, WHERE POSSIBLE, WITHOUT DELAY. For advice, contact a Poisons Information Centre or a doctor. Urgent hospital treatment is likely to be needed. In the mean time, qualified first-aid personnel should treat the patient following observation and employing supportive measures as indicated by the patient's condition. If the services of a medical officer or medical doctor are readily available, the patient should be placed in his/her care and a copy of the SDS should be provided. Further action will be the responsibility of the medical specialist. If medical attention is not available on the worksite or surroundings send the patient to a hospital together with a copy of the Ingestion SDS. Where medical attention is not immediately available or where the patient is more than 15 minutes from a hospital or unless instructed otherwise: INDUCE vomiting with fingers down the back of the throat, ONLY IF CONSCIOUS. Lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. NOTE: Wear a protective glove when inducing vomiting by mechanical means. 4.2 Most important symptoms
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