Product Information

PRODUCT DATA DOUGLAS LABORATORIES® 03/2018 1

TestoQuench™ for Men Hormone Specific Formulation™

DESCRIPTION TestoQuench™ for Men is a Hormone Specific Formulation™ of herbal ingredients that to help moderate the actions of testosterone. This combination of herbs is designed to support the healthy function of the prostate and other testosterone-sensitive tissues in men. ‡

The Hormone Specific Formulation™ line of products, provided by Douglas Laboratories® and formulated by Dr. Joseph J Collins, was created to support the optimal function of specific hormones through the use of hormone specific adaptogens and modulators of hormone signaling. This formulation may be used as part of a hormone health program with dietary and nutrient support. In addition, these formulations may be used by clinicians as an adjuvant to support optimal hormone health in patients who have been prescribed bioidentical hormone therapies. ‡

FUNCTIONS TestoQuench™ for Men is a unique combination of phytochemicals designed to promote healthy hormone balance by supporting the ideal function of testosterone-sensitive tissues. These phyto-compounds moderate tissue sensitivity to androgens or the actions of these hormones in part through targeting 5-alpha-reductase, an enzyme that converts testosterone to the more androgenic dihydrotestosterone. Saw palmetto has been demonstrated to moderate 5-alpha-reductase, and may support the function of the urethra. Oral piperine supports higher plasma concentrations of a variety of glycoproteins inhibiting P-glycoprotein (P-gp) and CYP34A. Preliminary studies also show it may inhibit testosterone 5ɑ-reductase.‡

INDICATIONS • Support for prostate health and testosterone balance in men. ‡

FORMULA (#202410) Serving size………………………. 2 veg. caps……..4 veg. caps Proprietary Blend...... 1,440 mg ……….2,880 mg Saw Palmetto berry Extract (Serenoa repens, standardized to 25% fatty acids), Magnolia officinalis bark Extract (standardized to 5% honokiol), Stinging Nettle leaf Extract (Urtica dioica, standardized to 1% silica), Holy Basil (Ocimum sanctum, leaf), Pygeum africanum (bark, standardized to 2.5% sterols) BioPerine® ……………………….10 mg ………… 20 mg (black pepper fruit extract/Piper nigrum) Other ingredients: Hydroxypropyl methylcellulose (capsule), silica, and hydroxypropyl cellulose.

BioPerine® is a registered trademark of Sabinsa Corporation

Non-GMO, Gluten Free

SUGGESTED USE As a dietary supplement, adults take 2-4 capsules daily with food or as directed by a healthcare professional.

INTERACTIONS Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.

STORAGE Store in a cool, dry place, away from direct light. Keep out of reach of children.

PRODUCT DATA DOUGLAS LABORATORIES® 03/2018 2

TestoQuench™ for Men Hormone Specific Formulation™

REFERENCES Gulcin I, Kufrevioglu OI, Oktay M, Buyukokuroglu ME. J Ethnopharmacol. 2004 Feb;90(2-3):205-15. [Urtica dioica L.] Kelm MA, Nair MG, Strasburg GM, DeWitt DL. Phytomedicine. 2000 Mar;7(1):7-13. [Ocimum sanctum Linn.]. Papaioannou M, et al. Invest New Drugs. 2010 Dec;28(6):729-43. [Pygeum africanum]. Prager N, Bickett K, French N, Marcovici G. J Altern Complement Med. 2002 Apr;8(2):143-52 Bharadwaj et al., JPET 302:645–650, 2002. [piperine] Gerber GS, Zagaja GP, Bales GT, Chodak GW, Contreras BA. Urology 1998;51(6):1003-1007. [saw palmetto] Saidi S, Stavridis S, Stankov O, Dohcev S, Panov S. Hyperplasia.Pril. 2017 Sep 1;38(2):123-129. [saw palmetto] Sinescu I, Geavlete P, Multescu R, Gangu C, Miclea F, Coman I, et al. Urol Int 86: 284–289 [saw palmetto] Hirata N, et al. Biol. Pharm. Bull. 30(12) 2402—2405 (2007). [piperine]

For more information on TestoQuench™ visit douglaslabs.com

Hormone Specific Formulation™ is a trademark of Your Hormones, Inc.

‡These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.