Communicable Diseases and Germ Theory in Colonial India – an Assessment*
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Hamilton's Forgotten Epidemics
Library and Archives Canada Cataloguing in Publication Ch2olera: Hamilton’s Forgotten Epidemics / D. Ann Herring and Heather T. Battles, editors. Includes bibliographical references and index. ISBN 978-0-9782417-4-2 Print catalogue data is available from Library and Archives Canada, at www.collectionscanada.gc.ca Cover Image: Historical City of Hamilton. Published by Rice & Duncan in 1859, drawn by G. Rice. http://map.hamilton.ca/old hamilton.jpg Cover Design: Robert Huang Group Photo: Temara Brown Ch2olera Hamilton’s Forgotten Epidemics D. Ann Herring and Heather T. Battles, editors DEPARTMENT OF ANTHROPOLOGY McMASTER UNIVERSITY Hamilton, Ontario, Canada Contents FIGURES AND TABLES vii Introduction Ch2olera: Hamilton’s Forgotten Epidemics D. Ann Herring and Heather T. Battles 2 2 “From Time Immemorial”: British Imperialism and Cholera in India Diedre Beintema 8 3 Miasma Theory and Medical Paradigms: Shift Happens? Ayla Mykytey 18 4 ‘A Rose by Any Other Name’: Types of Cholera in the 19th Century Thomas Siek 24 5 Doesn’t Anyone Care About the Children? Katlyn Ferrusi 32 6 Changing Waves: The Epidemics of 1832 and 1854 Brianna K. Johns 42 7 Charcoal, Lard, and Maple Sugar: Treating Cholera in the 19th Century S. Lawrence-Nametka 52 iii 8 How Disease Instills Fear into a Population Jacqueline Le 62 9 The Blame Game Andrew Turner 72 10 Virulence Victims in Victorian Hamilton Jodi E. Smillie 80 11 On the Edge of Death: Cholera’s Impact on Surrounding Towns and Hamlets Mackenzie Armstrong 90 12 Avoid Cholera: Practice Cleanliness and Temperance Karolina Grzeszczuk 100 13 New Rules to Battle the Cholera Outbreak Alexandra Saly 108 14 Sanitation in Early Hamilton Nathan G. -
October 24–26, 2021 2
SCIENCE · INNOVATION · POLICIES WORLD HEALTH SUMMIT BERLIN, GERMANY & DIGITAL OCTOBER 24–26, 2021 2 “No-one is safe from COVID-19; “All countries have signed up to Universal no-one is safe until we are all Health Coverage by 2030. But we cannot safe from it. Even those who wait ten years. We need health systems conquer the virus within their that work, before we face an outbreak own borders remain prisoners of something more contagious than within these borders until it is COVID-19; more deadly; or both.” conquered everywhere.” ANTÓNIO GUTERRES Secretary-General, United Nations FRANK-WALTER STEINMEIER Federal President, Germany “We firmly believe that the “All pulling together—this must rights of women and girls be the hallmark of the European are not negotiable.” Health Union. I believe this can NATALIA KANEM be a test case for true global Executive Director, United Nations Population Fund (UNFPA) health compact. The need for leadership is clear and I believe the European Union must as- sume this responsibility.” “The lesson is clear: a strong health URSULA VON DER LEYEN system is a resilient health system. Health President, European Commission systems and preparedness are not only “Governments of countries an investment in the future, they are the that are doing well during foundation of our response today.” the pandemic have not TEDROS ADHANOM GHEBREYESUS Director-General, World Health Organization (WHO) only shown political leader- ship, but also have listened “If we don’t address the concerns and to scientists and followed fears we will not do ourselves a favor. their recommendations.” In the end, it is about how technology SOUMYA SWAMINATHAN Chief Scientist, World Health can be advanced as well as how Organization (WHO) we can make healthcare more human.” BERND MONTAG President and CEO, Siemens Healthineers AG, Germany “The pandemic has brought to light the “Academic collabo ration is importance of digital technologies and in place and is really a how it can radically bridging partnership. -
Sir Charles Sherrington'sthe Integrative Action of the Nervous System: a Centenary Appreciation
doi:10.1093/brain/awm022 Brain (2007), 130, 887^894 OCCASIONAL PAPER Sir Charles Sherrington’sThe integrative action of the nervous system: a centenary appreciation Robert E. Burke Formerly Chief of the Laboratory of Neural Control, National Institute of Neurological Disorders, National Institutes of Health, Bethesda, MD, USA Present address: P.O. Box 1722, El Prado, NM 87529,USA E-mail: [email protected] In 1906 Sir Charles Sherrington published The Integrative Action of the Nervous System, which was a collection of ten lectures delivered two years before at Yale University in the United States. In this monograph Sherrington summarized two decades of painstaking experimental observations and his incisive interpretation of them. It settled the then-current debate between the ‘‘Reticular Theory’’ versus ‘‘Neuron Doctrine’’ ideas about the fundamental nature of the nervous system in mammals in favor of the latter, and it changed forever the way in which subsequent generations have viewed the organization of the central nervous system. Sherrington’s magnum opus contains basic concepts and even terminology that are now second nature to every student of the subject. This brief article reviews the historical context in which the book was written, summarizes its content, and considers its impact on Neurology and Neuroscience. Keywords: Neuron Doctrine; spinal reflexes; reflex coordination; control of movement; nervous system organization Introduction The first decade of the 20th century saw two momentous The Silliman lectures events for science. The year 1905 was Albert Einstein’s Sherrington’s 1906 monograph, published simultaneously in ‘miraculous year’ during which three of his most celebrated London, New Haven and New York, was based on a series papers in theoretical physics appeared. -
Introduction to Microbiology: Then and Now
© Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC (right) Courtesy of Jed Alan Fuhrman, University of Southern University (right) Courtesy of Jed Alan Fuhrman, (left) Courtesy of JPL-Caltech/NASA. California. CHAPTER 1 NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION Introduction© Jones & Bartlett Learning, LLC to © Jones & Bartlett Learning, LLC Microbiology:NOT FOR SALE OR DISTRIBUTION ThenNOT FOR and SALE OR DISTRIBUTIONNow © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC NOT FOR SALECHAPTER OR DISTRIBUTION KEY CONCEPTS NOT FOR SALE OR DISTRIBUTION 1-1 Microbial Communities Support and Affect All Life on Earth 1-2 The Human Body Has Its Own Microbiome 1-3 Microbiology Then: The Pioneers 1-4 The Microbial© WorldJones Is Cat& Bartlettaloged into Learning, Unique Groups LLC © Jones & Bartlett Learning, LLC 1-5 MicrobiologyNOT Now :FOR Challenges SALE Remain OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION © Jones & Bartlett Learning, LLC © Jones & Bartlett Learning, LLC Earth’s Microbiomes NOT FOR SALE OR DISTRIBUTION NOT FOR SALE OR DISTRIBUTION Space and the universe often appear to be an unlimited frontier. The chapter opener image on the left shows one of an estimated 350 billion large galaxies and more than 1024 stars in the known universe. However, there is another 30 invisible frontier here on Earth. This is the microbial universe, which consists of more than 10 microorganisms (or microbes for short). As the chapter opener image on the right shows, microbes might be microscopic in size, but, as we will see, they are magnificent in their evolutionary diversity and astounding in their sheer numbers. -
Metchnikoff and the Phagocytosis Theory
PERSPECTIVES TIMELINE Metchnikoff and the phagocytosis theory Alfred I. Tauber Metchnikoff’s phagocytosis theory was less century. Indeed, the clonal selection theory and an explanation of host defence than a the elucidation of the molecular biology of the proposal that might account for establishing immune response count among the great and maintaining organismal ‘harmony’. By advances in biology during our own era5. tracing the phagocyte’s various functions Metchnikoff has been assigned to the wine cel- Figure 1 | Ilya Metchnikoff, at ~45 years of through phylogeny, he recognized that eating lar of history, to be pulled out on occasion and age. This figure is reproduced from REF. 14. the tadpole’s tail and killing bacteria was the celebrated as an old hero. same fundamental process: preserving the However, to cite Metchnikoff only as a con- integrity, and, in some cases, defining the tributor to early immunology distorts his sem- launched him into the turbulent waters of evo- identity of the organism. inal contributions to a much wider domain. lutionary biology. He wrote his dissertation on He recognized that the development and func- the development of invertebrate germ layers, I first encountered the work of Ilya tion of the individual organism required an for which he shared the prestigious van Baer Metchnikoff (1845–1916; FIG. 1) in Paul de understanding of physiology in an evolution- Prize with Alexander Kovalevski. By the age of Kruif’s classic, The Microbe Hunters 1.Who ary context. The crucial precept: the organism 22 years, he was appointed to the position of would not be struck by the description of this was composed of various elements, each vying docent at the new University of Odessa, where, fiery Russian championing his theory of for dominance. -
Introduction to Plant Diseases
An Introduction to Plant Diseases David L. Clement, Regional Specialist - Plant Pathology Maryland Institute For Agriculture And Natural Resources Modified by Diane M. Karasevicz, Cornell Cooperative Extension Cornell University, Department of Plant Pathology Learning Objectives 1. Gain a general understanding of disease concepts. 2. Become familiar with the major pathogens that cause disease in plants. 3. Gain an understanding of how pathogens cause disease and their interactions with plants.· 4. Be able to distinguish disease symptoms from other plant injuries. 5. Understand the basic control strategies for plant diseases. Introduction to Plant Diseases The study of plant disease is covered under the science of Phytopathology, which is more commonly called Plant Pathology. Plant pathologists study plant diseases caused by fungi, bacteria. viruses and similar very small microbes (mlos. viroids, etc.), parasitic plants and nematodes. They also study plant disorders caused by abiotic problems. or non-living causes, associated with growing conditions. These include drought and freezing damage. nutrient imbalances, and air pollution damage. A Brief History of Plant Disea~es Plant diseases have had profound effects on mankind through the centuries as evidenced by Biblical references to blasting and mildew of plants. The Greek philosopher Theophrastus (370-286 BC) was the first to describe maladies of trees,. cereals and legumes that we today classify as leaf scorch, rots, scab, and cereal rust. The Romans were also aware of rust diseases of their grain crops. They celebrated lhe holiday of Robigalia that involved sacrifices of reddish colored dogs and catde in an attempt to appease the rust god Robigo. With the invention of the microscope in th~ seventeenth century fungi and bacteria associated with plants were investigated. -
Emil Von Behring (1854–1917) the German Bacteriologist
Emil von Behring (1854–1917) The German bacteriologist and Nobel Prize winner Emil von Behring ranks among the most important medical scientists. Behring was born in Hansdorff, West Prussia, as the son of a teacher in 1854. He grew up in narrow circumstances among eleven brothers and sisters. His desire to study medicine could only be realized by fulfilling the obligation to work as an military doctor for a longer period of time. Between 1874 and 1878 he studied medicine at the Akademie für das militärärztliche Bildungswesen in Berlin. In 1890, after having published his paper Ueber das Zustandekommen der Diphtherie- Immunität und der Tetanus-Immunität bei Thieren, he captured his scientific breakthrough. While having worked as Robert Koch’s scientific assistant at the Berlin Hygienic Institute he had been able to show – together with his Japanese colleague Shibasaburo Kitasato (1852–1931) – via experimentation on animal that it was possible to neutralize pathogenic germs by giving „antitoxins“. Behring demonstrated that the antitoxic qualities of blood are not seated in cells, but in the cell-free serum. Antitoxins recovered of human convalenscents or laboratorty animals, prove themselves as life-saving when being applied to diseased humans. At last – due to Behring’s discovery of the body’s own immune defence and due to his development of serotherapy against diphtheria and tetanus – a remedy existed which was able to combat via antitoxin those infectious diseases which had already broken out. Having developped a serum therapy against diphtheria and tetanus Behring won the first Nobel Prize in Medicine in 1901. Six years before, in 1895, he had become professor of Hygienics within the Faculty of Medicine at the University of Marburg, a position he would hold for the rest of his life. -
History of Microbiology: Spontaneous Generation Theory
HISTORY OF MICROBIOLOGY: SPONTANEOUS GENERATION THEORY Microbiology often has been defined as the study of organisms and agents too small to be seen clearly by the unaided eye—that is, the study of microorganisms. Because objects less than about one millimeter in diameter cannot be seen clearly and must be examined with a microscope, microbiology is concerned primarily with organisms and agents this small and smaller. Microbial World Microorganisms are everywhere. Almost every natural surface is colonized by microbes (including our skin). Some microorganisms can live quite happily in boiling hot springs, whereas others form complex microbial communities in frozen sea ice. Most microorganisms are harmless to humans. You swallow millions of microbes every day with no ill effects. In fact, we are dependent on microbes to help us digest our food and to protect our bodies from pathogens. Microbes also keep the biosphere running by carrying out essential functions such as decomposition of dead animals and plants. Microbes are the dominant form of life on planet Earth. More than half the biomass on Earth consists of microorganisms, whereas animals constitute only 15% of the mass of living organisms on Earth. This Microbiology course deals with • How and where they live • Their structure • How they derive food and energy • Functions of soil micro flora • Role in nutrient transformation • Relation with plant • Importance in Industries The microorganisms can be divided into two distinct groups based on the nucleus structure: Prokaryotes – The organism lacking true nucleus (membrane enclosed chromosome and nucleolus) and other organelles like mitochondria, golgi body, entoplasmic reticulum etc. are referred as Prokaryotes. -
Louis Pasteur
Britannica LaunchPacks | Louis Pasteur Louis Pasteur For Grades 6-8 This Pack contains: 5 ARTICLES 4 IMAGES 1 VIDEO © 2020 Encyclopædia Britannica, Inc. 1 of 47 Britannica LaunchPacks | Louis Pasteur Louis Pasteur (1822–95). The French chemist Louis Pasteur devoted his life to solving practical problems of industry, agriculture, and medicine. His discoveries have saved countless lives and created new wealth for the world. Among his discoveries are the pasteurization process and ways of preventing silkworm diseases, anthrax, chicken cholera, and rabies. Louis Pasteur. Archives Photographiques, Paris Pasteur sought no profits from his discoveries, and he supported his family on his professor’s salary or on a modest government allowance. In the laboratory he was a calm and exact worker; but once sure of his findings, he vigorously defended them. Pasteur was an ardent patriot, zealous in his ambition to make France great through science. Scholar and Scientist Louis Pasteur was born on Dec. 27, 1822, in Dôle, France. His father was a tanner. In 1827 the family moved to nearby Arbois, where Louis went to school. He was a hard-working pupil but not an especially brilliant one. When he was 17 he received a degree of bachelor of letters at the Collège Royal de Besançon. For the next three years he tutored younger students and prepared for the École Normale Supérieure, a noted teacher-training college in Paris. As part of his studies he investigated the crystallographic, chemical, and optical properties of © 2020 Encyclopædia Britannica, Inc. 2 of 47 Britannica LaunchPacks | Louis Pasteur various forms of tartaric acid. -
Miasma Vs Germ Theory Nina Kokayeff College of Dupage
ESSAI Volume 10 Article 24 4-1-2012 Dying to be Discovered: Miasma vs Germ Theory Nina Kokayeff College of DuPage Follow this and additional works at: http://dc.cod.edu/essai Recommended Citation Kokayeff, Nina (2013) "Dying to be Discovered: Miasma vs Germ Theory," ESSAI: Vol. 10, Article 24. Available at: http://dc.cod.edu/essai/vol10/iss1/24 This Selection is brought to you for free and open access by the College Publications at [email protected].. It has been accepted for inclusion in ESSAI by an authorized administrator of [email protected].. For more information, please contact [email protected]. Kokayeff: Dying to be Discovered: Miasma vs Germ Theory Dying to be Discovered: Miasma vs Germ Theory by Nina Kokayeff (Chemistry 1551) n 1832, Mozart‘s librettist Lorenzo da Ponte arranged for the visit of an Italian opera troupe to cholera-stricken Manhattan. They arrived to find the streets empty and silent except for ―I the ringing of church bells and the rattle of carts taking corpses to graveyards. Every resident who could had fled…‖ (Karlen, 1995). The cholera outbreak across many countries in the 19th century was the last of the great pandemics in which the miasma theory about the origin of disease was considered. New practices were developed to reduce the spread of the disease and a new picture of disease transmission emerged. The efficacy of these measures inspired other countries to follow suit, and soon encouraged some of the most groundbreaking biomedical research in history. Miasma Theory of disease contagion was popular for centuries in Western cultures. -
Microbiology: Example Saqs
Microbiology: Example SAQs Level 1: remembering. Frequently used task words: define, list, label, name. Can the student recall or remember the information? Identify TWO methods used to treat drinking water to reduce the risk of infection. This question just asks for the name of the methods, and nothing else is required. You don’t need to write an explanatory paragraph. You don’t even need to put the answer into a sentence. Boiling water Chlorination Microbiology: Example SAQs Level 2: understanding. Frequently used task words: describe, explain, identify & example. Can the student explain ideas or concepts? Explain the importance of using controls in microbial experiments. This question can have more than one answer and the length required is difficult to determine by looking at the question. Does your academic want an essay or do they want a one-liner? You can address this by looking at how much this question is worth. In an exam each mark is worth about a minute of time, so the amount you need to write depends on the mark value. Controls in microbial experiments allow us to validate the results. The control ensures that the microbial growth is a result of experimental conditions rather than contamination. For example, when testing the presence of microbes in food, the control agar plate is left unopened / unexposed. No growth in the control culture plate will make sure the microbial growth in experimental plates is from food rather than from the contamination of nutrient agar. Microbiology: Example SAQs Level 3: applying. Frequently used task words: apply, illustrate, solve, use & demonstrate. -
Nobel Laureate Surgeons
Literature Review World Journal of Surgery and Surgical Research Published: 12 Mar, 2020 Nobel Laureate Surgeons Jayant Radhakrishnan1* and Mohammad Ezzi1,2 1Department of Surgery and Urology, University of Illinois, USA 2Department of Surgery, Jazan University, Saudi Arabia Abstract This is a brief account of the notable contributions and some foibles of surgeons who have won the Nobel Prize for physiology or medicine since it was first awarded in 1901. Keywords: Nobel Prize in physiology or medicine; Surgical Nobel laureates; Pathology and surgery Introduction The Nobel Prize for physiology or medicine has been awarded to 219 scientists in the last 119 years. Eleven members of this illustrious group are surgeons although their awards have not always been for surgical innovations. Names of these surgeons with the year of the award and why they received it are listed below: Emil Theodor Kocher - 1909: Thyroid physiology, pathology and surgery. Alvar Gullstrand - 1911: Path of refracted light through the ocular lens. Alexis Carrel - 1912: Methods for suturing blood vessels and transplantation. Robert Barany - 1914: Function of the vestibular apparatus. Frederick Grant Banting - 1923: Extraction of insulin and treatment of diabetes. Alexander Fleming - 1945: Discovery of penicillin. Walter Rudolf Hess - 1949: Brain mapping for control of internal bodily functions. Werner Theodor Otto Forssmann - 1956: Cardiac catheterization. Charles Brenton Huggins - 1966: Hormonal control of prostate cancer. OPEN ACCESS Joseph Edward Murray - 1990: Organ transplantation. *Correspondence: Shinya Yamanaka-2012: Reprogramming of mature cells for pluripotency. Jayant Radhakrishnan, Department of Surgery and Urology, University of Emil Theodor Kocher (August 25, 1841 to July 27, 1917) Illinois, 1502, 71st, Street Darien, IL Kocher received the award in 1909 “for his work on the physiology, pathology and surgery of the 60561, Chicago, Illinois, USA, thyroid gland” [1].