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Evidence. Experience. Confi dence. bij • Invasieve candidiasis1 Supplement bij twintigste jaargang, april 2012 • Invasieve aspergillose2 Voorjaarsvergadering van de Nederlandse Vereniging voor Medische Microbiologie (NVMM) • Empirische antifungale therapie3 en de Koninklijke Nederlandse Vereniging voor Microbiologie (KNVM) C. albicans C. rugosaC. glabrataC. parapsilosisC. tropicalisC. kruseiC. guilliermondiiC. lipolyticaC. dubliniensisC. kefyrC. lusitaniaeA. fl avusA. fumigatusA. terreusA. nigerA. nidulans CANDIDA ALBICANS CANDIDA NON-ALBICANS ASPERGILLUS • Bewezen effectiviteit1 4 • Gunstig veiligheidsprofi el Papendal, 17 & 18 april 2012 Programma-overzicht 5,6 • Bij volwassenen en kinderen Abstracts Auteursindex Referenties: 1. Mora-Duarte J.: Comparison of caspofungin and amphotericin B for invasive candidiasis. N Eng J Med 347;2020-9, 2002. 2. Maertens J.: Effi cacy and safety of caspofungin for treatment of invasive aspergillosis in patients refractory to or intolerant for conventional antifungal therapy. CID 2004;39:000-000. 3. Walsh T.J.: Caspofungin versus Liposomal Amphotericin B for empirical antifungal therapy in patients with persistent fever and neutropenia. N Eng J Med 2004; 351:1391-402.4. David W. Denning: Echinocandin antifungal drugs. The Lancet 362: 1142-51, 2003.5. Walsh TJ: Pharmacokinetics, safety and tolerability of caspofungin in children and adolescents. AAC 49: 4536-4545, 2005. 6. Zaoutis TE: A prospective, multicenter study of caspofungin for treatment of documented candida or aspergillus infections in pediatric patients. Pediatrics 123:877-884, 2009. 20e jaargang . april 2012 . Supplement Raadpleeg eerst de volledige productinformatie alvorens CANCIDAS voor te schrijven M Merck Sharp & Dohme BV, Postbus 581, 2003 PC Haarlem Tel. 0800-9999000, email [email protected] 1110CAN09NL539J1109 www.msd.nl, www.univadis.nl Evidence. Experience. Confi dence. Cans539J_Adv_210x297.indd 1 18-02-11 15:40 Organizing committee Poster committee Prof. dr. J.A.G. van Strijp, chair Prof. dr. ir. M.H. Zwietering, chair Dr. A.J.W. van Alphen Dr. W. van Schaik Prof. dr. W. Bitter Dr. A.M. Wensing Prof. dr. S. Brul Prof. dr. L. Dijkhuizen Dr. B. Duim Dr. J.W.B. van der Giessen Prof. dr. ir. M.S.M. Jetten Prof. dr. M.P.G. Koopmans Prof. dr. P. Rottier Prof. dr. P.H.M. Savelkoul Prof. dr. L.J. Stal Dr. B.J.M. Vlaminckx Dr. M.J.H.M. Wolfhagen Prof. dr. H.A.B. Wösten Prof. dr. ir. M.H. Zwietering The Scientific spring meeting is organized by the Royal Dutch Society of Microbiology (KNVM) and the Dutch Society of Medical Microbiology. Meeting secretariat: P.O. Box 2428 5202 CK ’s-Hertogenbosch Tel 073 - 700 35 00 Fax 073 - 700 35 05 [email protected] www.congresscompany.com Ned Tijdschr Med Microbiol 2012;20:Supplement S1 Immuungecompromitteerd en ook nog een schimmelinfectie SponsorS and exhibit OrS Als het afweersysteem Abbott Mediaproducts Alere Health Mediphos Medical Supplies Astellas Pharma NL Menarini Diagnostics BaseClear Meridian Bioscience even de kracht mist, ruimt BD Minigrip Nederland Beldico Belgium MIPS ® * Bio Rad Laboratories MLS AmBisome schimmels op Bio Trading Benelux MSD Biognost Oxoid Biolegio Qiagen Benelux BioMerieux Benelux R-Biopharm Bodégro Roche Diagnostics Boom Sarstedt Bruker Nederland Siemens Healthcare Diagnostics Cepheid Benelux Snijders Scientific Check-Points Tieto Netherlands Healthcare Clean Air Techniek Clindia Benelux Supported by: DiaSorin Elitech Benelux antonie van Leeuwenhoek Stichting Gen-Probe Gilead Sciences ITK Diagnostics Kiestra Lab Automation Labolutions Luminex Gilead Sciences Netherlands B.V. amfotericine B in liposomen Strawinskylaan 779 1077 XX Amsterdam www.gilead.com kracht, verpakt in liposomen *AmBisome is geregistreerd voor de behandeling van ernstige systemische mycosen, veroorzaakt door Candida albicans of Aspergillus spp. Voor productinformatie zie elders in dit blad. 131/NL/11-07/PM/1104b Ned Tijdschr Med Microbiol 2012;20:Supplement S3 exhibitiOn - Room Sydney booth number Company booth number Company 1 Mediaproducts 25 Bio Rad Laboratories 2 Elitech Benelux 26 Snijders Scientific 3 Boom 27 Gen-Probe 6 DiaSorin 28 Check-Points 7 Gilead Sciences 29 ITK Diagnostics 8 Biolegio 30 Bruker Nederland 10 Kiestra Lab Automation 31 Beldico Belgium 11 Astellas Pharma NL 32 Luminex 12 BaseClear 33 Oxoid 13 Labolutions 34 Minigrip Nederland 14 MLS 35 Bodégro 15 Siemens Healthcare Diagnostics 36 Clean Air Techniek 16 MSD 37 Clindia Benelux 17 MIPS 38 Mediphos Medical Supplies 18 Biognost 39 R-Biopharm 19+20 BD 40 BioMerieux Benelux 21+22 Abbott 41 Sarstedt 23 Alere Health 42 Bio Trading Benelux 43 Roche Diagnostics Ned Tijdschr Med Microbiol 2012;20:Supplement S4 exhibitiOn - F Oyer 1 & 2 booth number Company 44 Qiagen Benelux 49 Tieto Netherlands Healthcare 50 Cepheid Benelux 54 Menarini Diagnostics 55 Meridian Bioscience Ned Tijdschr Med Microbiol 2012;20:Supplement S5 Floorplan Pa PendaL Foyer 1 & 2 Exhibition, posters & coffee/tea/lunch Ned Tijdschr Med Microbiol 2012;20:Supplement S6 SCientiFiC Programme tUeSDAY aPRIL 17 2012 15:45 - 16:00 high acquisition rates of eSbL producing enterobacteriaceae among dutch travelers O008 S. Paltansing 09:00 - 09:30 registration athene a West nile virus emergence in europe athene b/C Chairs: C. Reusken and M. Koopmans 09:30 - 11:00 Plenary session 14:30 - 15:00 emergence of West nile virus in Greece Chair: W. Bitter O009 A. Papa (Greece) 09:30 - 10:15 Complex dynamics in microbial communities 15:00 - 15:30 West nile virus non-coding RNA: effects on O001 J. Huisman (The Netherlands) pathogenicity and mosquito transmission 10:15 - 11:00 electromicrobiology O010 G.P. Pijlman O002 D.R. Lovley (USA) 15:30 - 15:45 the role of immature virus particles in dengue pathogenesis 11:00 - 11:30 Coffee/tea break O011 J.M. da Silva Voorham 15:45 - 16:00 detection of dengue nS1 in travelers: a comparison of the performance of three rapid athene b/C diagnostic tests with the Platelia nS1 antigen 11:30 - 13:30 Plenary session & award ceremony eLiSa Chair: B.J.M. Vlaminckx O012 C. Liem 11:30 - 12:15 the curious road from poxvirus tropism to oncolytic virotherapy room 3 Surprising infectious diseases and association O003 G. McFadden (USA) with pathogens 12:15 - 13:00 Sustainability of antibiotic efficacy: from Chair: E.J. Kuijper containment to restorative approaches 14:30 - 14:45 an outbreak of histoplasmosis misdiagnosed O004 F. Baquero (Spain) as miliary tuberculosis among participants of a tropical biology course in Uganda 13:00 - 13:30 award ceremony O013 M.A. Schouten 14:45 - 15:00 Outbreak of a multi-drug resistant 13:30 - 14:30 Lunch Pseudomonas aeruginosa on the intensive care unit of a tertiary care hospital in the netherlands; a case-control study to identify athene b/C sources and risk factors 13:30 - 14:30 Lunch Symposium diasorin: the new Liaison® O014 M. Knoester xL Murex hepatitis and retrovirus assays: experiences from the field 15:00 - 15:15 the curious case of a man who slept in the daytime Chair: Dr. Ph.H. Rothbart Dr. M. Schutten, Erasmus MC, Rotterdam O015 M.B.B. McCall Dr. C.F.M. Linssen, Atrium Medisch Centrum, 15:15 - 15:30 appendiceal spirochaetosis in children Heerlen O016 L.J. Westerman athene a 15:30 - 15:45 asymptomatic carriage of Mycoplasma 13:30 - 14:30 KnVM business meeting pneumoniae in the upper respiratory tract of children 14:30 - 16:00 Parallel sessions O017 C. Vink 15:45 - 16:00 Pneumococcal pneumonia: the association between clinical severity and serotype athene b/C From STEC to hUSeC – EHEC yesterday and today O018 A.J.H. Cremers Chair: R.A. Coutinho 14:30 - 15:00 EHEC O104:h4: Phylogenetic origin and room 4/5 Multiresistent microorganisms in hospitals: pathogenesis recognizing outbreaks, management and responsibilities O005 A. Mellmann (Germany) Chair: M. Vos 15:00 - 15:30 Molecular epidemiology and clinical risk assessment of Shiga-producing E. coli (SteC) 14:30 - 15:00 recognizing outbreaks: pitfalls in diagnosing carbapenemase producing microorganisms O006 A.W. Friedrich O019 T. van Ossewaarde 15:30 - 15:45 Subtractive epidemiology of eSbL producing enterobacteriaceae in the northern dutch- German border region O007 S. Surie Ned Tijdschr Med Microbiol 2012;20:Supplement S8 15:00 - 15:15 Management of outbreaks: guidelines and athene b/C Psittacosis responsibilities – WiP guidelines on multi- Chairs: B. Mulder and W. Dorigo resistant microorganisms 16:30 - 17:00 Microbiology and pathogenesis of psittacosis O020 I.J.B. Spijkerman O032 D. Vanrompay (Belgium) 15:15 - 15:30 Management of outbreaks: guidelines and responsibilities – responsibilities in an 17:00 - 17:15 diagnostics and typing of psittacosis outbreak situation O033 E. Heddema O021 G. Haringhuizen 17:15 - 17:30 Veterinary aspects and control of psittacosis 15:30 - 15:45 Management of outbreaks: guidelines and O034 O.F.J. Stenvers responsibilities – SWAB guidelines on the treatment of multiresistant microorganisms 17:30 - 17:45 Multi locus sequence typing of Chlamydia psittaci and Chlamydia pecorum from birds O022 J.W. Mouton and mammals reveals an association between 15:45 - 16:00 national surveillance of outbreaks Chlamydia genotypes and host species O023 C.H.E. Boel O035 Y. Pannekoek 17:45 - 18:00 the challenges of serological prediction of chronic Q fever room 6/7 role of oxygen in lifestyle choices of microbial pathogens O036 L.M. Kampschreur Chairs: J. Stoof and A. van Vliet 14:30 - 15:00 bacterial oxygen sensing: lessons taught by athene a Mycology Escherichia coli Chairs: H.A.B. Wösten and P. Verweij O024 J. Green (United Kingdom) 16:30 - 16:45 discovery of a new azole resistance 15:00 - 15:30 General and oxidative stress responses in mechanism in Aspergillus fumigatus through foodborne pathogens whole genome sequencing and sexual crossing O025 T. Abee O037 S.M.T. Camps 15:30 - 15:45 translational regulation of the respiratory 16:45 - 17:00 Mannitol-1-phosphate dehydrogenase is electron transport chain of Neisseria menin- essential for the development of extreme gitidis by the Fur controlled small non-coding stress resistant fungal ascospores RNA nrrF O038 T.T.