TiE Houston Welcomes you to

“Personalized Cancer Care and the Innovations Making It Today’s Reality” TiE Houston Keynote Address

Date: Thursday, November 6, 2014 Time: 5.30 – 9:00 pm Location: HESS Club, 5430 Westheimer road, Houston, TX 77056 FEE: TiE Houston Charter Members: FREE with 2 FREE drink tickets; TiE Houston General Members: $15 Non-Members: $30; IACCGH: 30 FREE tickets - Contact Jagdip Ahluwalia at [email protected] For Registration: https://houston.tie.org

Distinguished Panelists Dr. Lynda Chin, Professor and Chair, Department of Genomic Medicine and Scientific Director, Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center Stephen Gold, Vice President, Marketing & Sales Operations, IBM Solutions, IBM Software Group Manoj Saxena, Founding General Partner of The Entrepreneur’s Fund

Topic Overview A potentially revolutionary paradigm shift in healthcare – the emergence of personalized medicine – is taking place right under our eyes. This shift is driven by the confluence of three elements – unprecedented amounts of data generation, the ability to process and interpret streams of Big Data, and the emergence of targeted therapies. Join us to learn more about how these threads come together as personalized cancer care makes a difference in our lives.

IBM Watson signals a critical turning point in the evolution of information technology. Watson is a cognitive technology that processes information more like a human than a computer—by understanding natural language, generating hypotheses based on evidence, and learning as it goes. Watson “gets smarter” in three ways: by being taught by its users, by learning from prior interactions, and by being presented with new information. This means it allows users to more fully understand and use all the available data.

A major focus of Dr. Chin’s current efforts is to bring to bear on the cancer crisis not only the transformative potential of genomics, but also of technologies and innovative strategies such as Watson. Dr. Chin has launched the N-of-ALLTM Initiative with the goal of enhancing effectiveness of cancer care and research. A pilot project in Leukemia has created an Adaptive Patient-Oriented Longitudinal Learning and Optimization (APOLLO) platform that integrates genomic research in context of clinical care and MD Anderson’s Oncology Expert AdvisorTM powered by IBM-Watson works to facilitate democratization of oncology expertise. After a career in creating a range of innovative technology solutions including serving as GM for IBM-Watson, Manoj Saxena founded The Entrepreneur’s Fund (TEF) as a vehicle to advance continued developments in Big Data and Cognitive Computing space. TEF focuses on true seed-stage investing with successful serial entrepreneurs with a focus on transformative cloud-based cognitive and B2B technologies. Manoj will other emerging technologies and applications that promise to impact or event transform our lives in the decades ahead. Contact For More Information: [email protected]

Event Sponsor: IACCGH (Indo-American Chamber of Commerce of Greater Houston) & Saviance Healthcare

Speaker Bios

Dr. Lynda Chin is the founding Chair of the Department of Genomic Medicine at The University of Texas MD Anderson Cancer Center. She also serves as the Scientific Director of the Institute for Applied Cancer Science at MD Anderson, which merges the best attributes of academia and industry to enable science- driven drug discovery.

Dr. Chin is a leader in translational genomic medicine, and her research program spans the fields of transcription, telomere biology, mouse models of human cancer, cancer genomics, and personalized cancer medicine. She holds a number of leadership roles in The Cancer Genome Atlas, a comprehensive effort by the National Institutes of Health to accelerate understanding of the molecular basis of cancer through the use of genomics. Dr. Chin is also a member of the Scientific Steering Committee of the International Cancer Genome Consortium and the Institute of Medicine.

For 13 years prior to joining The University of Texas MD Anderson Cancer Center in 2011, Dr. Chin was a professor of Dermatology at Dana-Farber Cancer Institute and Harvard Medical School, and a senior associate member of the Broad Institute of Massachusetts Institute of Technology and Harvard University. She was also the scientific director of the Belfer Institute for Applied Cancer Science.

At MD Anderson Cancer Center, Dr. Chin has championed a new model of integration, collaboration and cooperation between research and clinical care enterprises, between academia and industry, to bring to bear the power of technology and patient data on the cancer problem. In particular, she has been the visionary and driver behind MD Anderson’s Oncology Expert AdvisorTM powered by IBM-Watson, and the APOLLO big data platform that supports it. Dr. Chin earned a Doctor of Medicine from Albert Einstein College of Medicine and is a board-certified dermatologist.

Stephen Gold is Vice President, WW Marketing & Sales Operations, Watson Solutions, IBM Software Group. He has overall responsibility for the brands marketing strategy, marketing communications, social media, public relations, analyst relations, sales enablement, demand generation, and events. As a member of the senior leadership team he is working to help commercialize industry solutions based on IBM’s transformative Watson technology.

Prior to joining IBM, Stephen was Vice President of Marketing (CMO) for SPSS, acquired by IBM in 2009. As President of the Aberdeen Group, a Harte-Hanks Company, Stephen oversaw all aspects of the publically traded market research organization, which covered twenty-six distinct technology markets. Previous to this Stephen successfully scaled and sold two Silicon Valley based startups; Azerity to ModelN in 2006 in the capacity as CEO and Digital Market to Agile (now Oracle), as its CMO.

Stephen has a twenty-year winning track record of leading successful enterprises and building businesses across industries (technology, software and services) and geographies (domestic and international) for both high growth private and multi-billion dollar publicly traded corporations. Stephen holds a B.S. in Mechanical Engineering from the University of Illinois at Champaign-Urbana and graduated with distinction from Carnegie Mellon University with an MBA. The Pennsylvania Small Business Association and Carnegie Mellon have both recognized him as “Entrepreneur of the Year”. Stephen has appeared on CNN and is a featured speaker at various conferences and universities.

Manoj Saxena is a founding General Partner of The Entrepreneur’s Fund where he directs investments in Big Data and Cognitive Computing space. Saxena is a successful CEO and serial entrepreneur and most recently was IBM’s General Manager for the Watson Division.

Prior to IBM, Saxena successfully founded, scaled, and sold two venture-backed software companies within a five-year span. Webify, an emerging leader in industry-specific SOA middleware, which was acquired by IBM in 2006, and Exterprise, a business process collaboration company, purchased by Commerce One in 2001. Saxena holds two U.S. patents for web services technologies.

Under his leadership at IBM, his team built the world's first cognitive computing systems in Healthcare, Financial Services, and Retail. He received the IBM Chairman's award for Watson commercialization and helped the formation of a Watson Business Group in January 2014 with investments of over $1 Billion and 2,000 people.

He currently serves on several boards including the Federal Reserve Bank of Dallas, San Antonio Branch, Communities In Schools, and the Saxena Family Foundation. He is the recipient of multiple awards including “Entrepreneur of the Year”, “IT Technologist of the Year”, “Fast Company Most Creative People” List, “Civic Entrepreneurship Award” and the “Distinguished Alumni Award” from Michigan State University from where he received his MBA in 1991.

Saxena holds a masters degree in business administration from Michigan State University, and a masters in management sciences from the Birla Institute of Technology & Science in Pilani, India. Twitter: manojsaxena LinkedIn: www.linkedin.com/in/manojsaxena Personal: www.saxenafoundation.com