Showcase 2019 Joining Instructions

Arrival and registration from 08:30. Event begins at 09:30 @Insigneo #InsigneoSC19

Venue Information The , Clarkson Street S10 2TQ, is situated in a pedestrianised area near the Student Union in the area between Durham Road, Clarkson Street and Western Bank. It can be approached on foot from any of these directions (see the map below), but perhaps most obviously from Durham Road. A map of the campus and further travel instructions are available on the University of website.

Travel Information By Car We recommend that when travelling from the north, east and south you should approach Sheffield by the M1 (and M18 if necessary). From the west, use the M60 and A628 Woodhead Pass, following the signs for Sheffield. If in doubt, follow the road signs labelled ''. The postcode for the main University building on Western Bank, , is S10 2TN. Car parking is limited around the University. The nearest car park is the multi storey access on Durham Road. Another multi storey car park is Rockingham Street, Sheffield S1 4NL.

By Train Arrive at and either take a taxi to the Octagon Centre or follow Tram/Bus directions below.

By Tram Trams link the railway station and the city centre directly to the University. The tram stop is located at the back of the railway station. Trams from the station to the University run on the Blue route (destination ). Trams from the city centre to the University run on both the Blue route and the Yellow route (destination Middlewood).

By Bus Buses to the University are frequent and inexpensive. From the Transport Interchange/coach station you can take the number 120 directly to the University. Other buses from the city centre include the 51, 52 and 95. Get off at the University.

Contacting the Organiser Please contact Lesley Statham: [email protected], 0114 22 20162 (on the day contact: 07908 671 128 or, via the porters, 0114 222 8886).

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Showcase Venue – The Octagon Centre, Sheffield

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Pedestrian access from Durham Road

Showcase Venue – The Octagon Centre, Sheffield

Octagon Centre from Durham Road (looking toward Firth Court)

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Insigneo Showcase 2019 Programme

08:30 Arrival, registration and refreshments An opportunity to network, browse the poster presentations, and visit the Exhibition Area showcasing commercial in silico activities and interactive demonstrations

Welcome from Professor Koen Lamberts – President and Vice‐Chancellor, University of Sheffield 09:30 Professor Claudia Mazzà – Interim Executive Director of Insigneo, University of Sheffield

09:45 Plenary Speaker: Professor Liesbet Geris, President of the Virtual Physiological Human Institute and Professor in Biomechanics and Computational Tissue Engineering, University of Liège ‘From data to knowledge using in silico technologies: examples from regenerative medicine’

10:45 Coffee break ‐ enjoy a break, network, visit the Exhibition Area and browse poster presentations

11:15 Insigneo Early Career Session Introduced by: Dr Rebecca Gosling, Interim Director of Clinical Translation, Insigneo Insitute, University of Sheffield 11:15 Key Note Speaker: Dr Pankaj Garg, NIHR Clinical Lecturer in Cardiology, University of Sheffield ‘Role of cardiovascular Magnetic Resonance Imaging in precision diagnostic technology’ 11:30 Invited power pitches from Early Career Researchers Jose Ricardo Aguilar Cosme, Elisabeth Kugler, Jessica Magallanes, Erica Montefiori, Sara Oliviero, Bryant Roberts, Bilal Tahir, Rodrigo Siqueira de Souza, Samuel Stroud, Jonathan Taylor

12:30 Lunch ‐ enjoy a break and network 13:00 Exhibition – visit the Exhibition Area and browse poster presentations

14:00 David Hughes – Medical Director, Sheffield Teaching Hospitals NHS Foundation Trust 'Introduction and overview from Sheffield Teaching Hospitals’

14.05 The role of medical imaging in in silico medicine Introduced by: Professor Jim Wild, Director of Research, Insigneo Insitute, University of Sheffield Dr Xinshan (Shannon) Li, Department of Mechanical Engineering ‘Building virtual organs: From in silico Medicine to Forensics’ Dr Andrew Swift, Department of Infection, Immunity and Cardiovascular Disease ‘Clinical applications of machine learning in cardiac imaging’ Dr Rhoda Hawkins, Department of Physics & Astronomy ‘Deforming cancer cell nuclei: images and modelling’

15:00 Mathematical approaches in in silico medicine Introduced by: Dr Maria‐Cruz Villa‐Uriol, Lecturer in Computer Science, University of Sheffield Dr Haiping Lu, Department of Computer Science ‘Interpretable Machine Learning’ Dr Miguel Juarez, Department of Maths & Statistics ‘In silico augmented clinical trials: the StriTuVaD project’ Dr Paul Watton, Department of Computer Science ‘Modelling the mechanobiology of intracranial aneurysm stability/enlargement: a patient‐specific framework’

15:50 Closing remarks and poster prize giving Dr Andrew Narracott, Director of Operations, Insigneo Institute, University of Sheffield

16:10 – 17:00 Drinks reception

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The Insigneo Institute The Insigneo Institute for in silico Medicine is a research institute established as a collaborative initiative between the University of Sheffield and Sheffield Teaching Hospital NHS Foundation Trust, where we develop sophisticated computer simulations of human physiology, in health and disease, in order to improve clinical diagnosis and treatment. With a multi‐disciplinary membership of over 150 academics and clinicians, Insigneo is Europe’s largest centre dedicated to these activities, in the emerging discipline known as in silico medicine.

The Exhibition Area The 2019 Showcase in silico medicine’s latest commercial applications and developments from our industrial partners. Here you will find many of Europe’s foremost medical industry organisations presenting the latest, most dynamic information on their cutting‐edge developments, and their interface with the world of in silico technology. Demonstrations by our industrial partners will take place during the day: Time Summary 11:00 Synopsys Medical Device Development with Simpleware Software Learn how Simpleware software provides 3D image processing solutions for the design and optimization of medical devices.

13:30 Dassault Systèmes Simulation in the Life Sciences – a look ahead Life Sciences for Dassault Systèmes covers 3 segments – medical devices, Pharma/biotech, and patient care ‐ that have hitherto been quite distinct, at least in terms of computational tools and technologies. However, all segments are ultimately concerned with patient health and satisfaction, and this presentation will demonstrate how Virtual Human Modelling R&D at Dassault Systèmes is developing solutions for all 3 segments and in the process deepening, diversifying, and democratizing the use of simulation in healthcare.

13:40 COMSOL COMSOL Multiphysics®: Providing software for accurate FEA modelling The COMSOL Multiphysics® software is used for simulating designs, devices, and processes in all fields of engineering, manufacturing, and scientific research. A particular strength is its ability to account for coupled or multiphysics phenomena, for example, coupling fluid and structural effects in a single simulation. COMSOL®’s ability to easily incorporate user‐defined equations allows for flexible customisation of your models.

13:50 Materialise Image based Computational Modelling for Clinical Care This short session will demonstrate an overview of a wide variety of applications in the medical field using Materialise's image based technology.

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