Anti-SPDYA Polyclonal Antibody Cat: K003260P Summary

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Anti-SPDYA Polyclonal Antibody Cat: K003260P Summary: 【Product name】: Anti-SPDYA antibody 【Source】: Rabbit 【Isotype】: IgG 【Species reactivity】: Human Mouse Rat 【Swiss Prot】: Q5MJ70 【Gene ID】: 245711 【Calculated】: MW:36kDa 【Observed】: MW:45kDa 【Purification】: Affinity purification 【Tested applications】: WB 【Recommended dilution】: WB 1:500-2000. 【WB Positive sample】: A549,Mouse ovary,Mouse testis 【Subcellular location】: Nucleus 【Immunogen】: Recombinant protein of human SPDYA 【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background: Speedy A, also known as SPDYA, SPDY1, Ringo3 or SPY1, is a 313 amino acid protein that localizes to the nucleus and belongs to the speedy/ringo family. Expressed at high levels in testis and at lower levels in brain, kidney, heart, bone marrow, colon, lung, liver spleen and placenta, Speedy A functions to regulate the G1/S phase transition of the cell cycle, specifically by binding to and activating Cdc2 p34, Cdk2 and p27. Additionally, Speedy A mediates cell survival during DNA damage, suggesting that Speedy A plays a role in proper cell cycle progression throughout the life of the cell. Multiple isoforms of Speedy A exist due to alternative splicing events. The gene encoding Speedy A maps to human chromosome 2, which encodes over 1,400 genes and comprises nearly 8% of the human genome. Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information Verified picture Western blot analysis with SPDYA antibody diluted at 1:1000 Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information.

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CDKN1B-Y88 Antibody Purified Rabbit Polyclonal Antibody (Pab) Catalog # Ap20721b
10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 CDKN1B-Y88 Antibody Purified Rabbit Polyclonal Antibody (Pab) Catalog # AP20721b Specification CDKN1B-Y88 Antibody - Product Information Application WB,E Primary Accession P46527 Other Accession Q60439 Reactivity Human Predicted Hamster Host Rabbit Clonality Polyclonal Isotype Rabbit IgG CDKN1B-Y88 Antibody - Additional Information Gene ID 1027 Other Names Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, Western blot analysis of lysate from MCF-7 p27Kip1, CDKN1B, KIP1 cell line, using CDKN1B-Y88 (Cat. #AP20721b). AP20721b was diluted at Target/Specificity 1:1000. A goat anti-rabbit IgG H&L(HRP) at This antibody is generated from a rabbit 1:5000 dilution was used as the secondary immunized with a KLH conjugated synthetic antibody. Lysate at 35ug. peptide between 81-113 amino acids from human. CDKN1B-Y88 Antibody - Background Dilution WB~~1:1000 Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin Format E- and cyclin A-CDK2 complexes. Forms a Purified polyclonal antibody supplied in PBS complex with cyclin type D-CDK4 complexes with 0.09% (W/V) sodium azide. This antibody is purified through a protein A and is involved in the assembly, stability, and column, followed by peptide affinity modulation of CCND1- CDK4 complex purification. activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes Storage depending on its phosphorylation state and/or Maintain refrigerated at 2-8°C for up to 2 stoichometry. weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw CDKN1B-Y88 Antibody - References cycles.
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