Gunther S. Stent Papers, 1915-1998
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書 名 等 発行年 出版社 受賞年 備考 N1 Ueber Das Zustandekommen Der
書 名 等 発行年 出版社 受賞年 備考 Ueber das Zustandekommen der Diphtherie-immunitat und der Tetanus-Immunitat bei thieren / Emil Adolf N1 1890 Georg thieme 1901 von Behring N2 Diphtherie und tetanus immunitaet / Emil Adolf von Behring und Kitasato 19-- [Akitomo Matsuki] 1901 Malarial fever its cause, prevention and treatment containing full details for the use of travellers, University press of N3 1902 1902 sportsmen, soldiers, and residents in malarious places / by Ronald Ross liverpool Ueber die Anwendung von concentrirten chemischen Lichtstrahlen in der Medicin / von Prof. Dr. Niels N4 1899 F.C.W.Vogel 1903 Ryberg Finsen Mit 4 Abbildungen und 2 Tafeln Twenty-five years of objective study of the higher nervous activity (behaviour) of animals / Ivan N5 Petrovitch Pavlov ; translated and edited by W. Horsley Gantt ; with the collaboration of G. Volborth ; and c1928 International Publishing 1904 an introduction by Walter B. Cannon Conditioned reflexes : an investigation of the physiological activity of the cerebral cortex / by Ivan Oxford University N6 1927 1904 Petrovitch Pavlov ; translated and edited by G.V. Anrep Press N7 Die Ätiologie und die Bekämpfung der Tuberkulose / Robert Koch ; eingeleitet von M. Kirchner 1912 J.A.Barth 1905 N8 Neue Darstellung vom histologischen Bau des Centralnervensystems / von Santiago Ramón y Cajal 1893 Veit 1906 Traité des fiévres palustres : avec la description des microbes du paludisme / par Charles Louis Alphonse N9 1884 Octave Doin 1907 Laveran N10 Embryologie des Scorpions / von Ilya Ilyich Mechnikov 1870 Wilhelm Engelmann 1908 Immunität bei Infektionskrankheiten / Ilya Ilyich Mechnikov ; einzig autorisierte übersetzung von Julius N11 1902 Gustav Fischer 1908 Meyer Die experimentelle Chemotherapie der Spirillosen : Syphilis, Rückfallfieber, Hühnerspirillose, Frambösie / N12 1910 J.Springer 1908 von Paul Ehrlich und S. -
POPPER's GEWÖHNUNGSTHEORIE ASSEMBLED and FACED with OTHER THEORIES of LEARNING1 Arne Friemuth Petersen2
POPPER’S GEWÖHNUNGSTHEORIE ASSEMBLED AND FACED WITH OTHER THEORIES OF LEARNING1 Arne Friemuth Petersen2 Former Professor of General Psychology University of Copenhagen Abstract. With the publication of Popper’s Frühe Schriften (2006), renewed possibilities for inquiring into the nature and scope of what may be termed simply ‘Popperian Psychology’ have arisen. For although Popper would never have claimed to develop such psychology there is, however, from his earliest to his last works, a wealth of recommendations as to how to come to grips with problems of the psyche without falling victim of inductivist and subjectivist psychology. The fact that most theories of learning, both traditional and modern, have remained inductivist, and therefore logically invalid, places Popper’s hypothetico- deductive approach to learning and the acquisition of knowledge among the most important conjectures in that entire domain, akin to Edelman’s biological theory of consciousness. Central to Popper’s approach and his final rejection of all inductive procedures is his early attempt at a theory of habit-formation, Gewöhnungstheorie (in ‘Gewohnheit’ und ‘Gesetzerlebnis’ in der Erziehung, 1927) – a theory not fully developed at the time but nevertheless of decisive importance for his view on education and later works on epistemology, being ‘of lasting importance for my life’ (2006, p. 501). Working from some of the original descriptions and examples in ‘Gewohnheit’ und ‘Gesetzerlebnis’, updated by correspondence and discussions with Popper this paper presents a tentative reconstruction of his Gewöhnungstheorie, supplemented with examples from present-day behavioural research on, for example, ritualisation of animal and human behaviour and communication (Lorenz), and briefly confronted with competing theories, notably those by representatives of the behaviourist tradition of research on learning (Pavlov and Kandel). -
Biographical Notes on Scientists Involved in the Asilomar Process M.J
International Dimensions of Ethics Education in Science and Engineering Case Study Series: Asilomar Conference on Laboratory Precautions Appendix D: Biographical Notes on Scientists involved in the Asilomar Process M.J. Peterson Version 1, June 2010 Edward A. Adelberg (1920-2009). PhD Yale 1949. Chair of Yale Department of Microbiology 1961-64 and 1970-72; a founding member of Yale Department of Genetics. Deputy Provost for the Biomedical Sciences, 1983-91. Specialist in plasmid biochemistry of E. coli. Ephraim Anderson (1911-2006). M.D., Durham University. Served in the Royal Army Medical Corps during World War II where he developed interests in Epidemiology. Researcher in Enteric Laboratory of the British Public Health Laboratory Service 1947, Deputy Director 1952, Director 1954-1978. Came to public notice for tracing sources of typhoid outbreaks in Zermatt (1963) and Aberdeen (1964). Built on earlier work by Japanese researchers to demonstrate the plasmid-based pathways by which bacteria could spread antibiotic resistance to others and became the world’s leading expert on antibiotic resistance. Also prominent in efforts to limit use of antibiotics in raising animals. Fellow of the Royal Society 1968; Companion of the Order of the British Empire 1976. Eric Ashby, Baron Ashby (1904-1992). Lecturer in Botany, Imperial College London 1931-35; Reader in Botany Bristol University 1935-37; Professor of Botany University of Sydney 1938-1946; Chair of Botany, University of Manchester 1947-50. Turned to administration as President and Vice-Chancellor of Queen's University, Belfast 1950-59; Master of Clare College in Cambridge University 1959-67 and Vice-Chancellor of Cambridge University 1967-1969. -
Symposium in Honor of Nobel Laureate Werner Arber
Symposium th Birthday in honor of Nobel Laureate Werner Arber th Birthday Prof. em. Werner Arber Professor emeritus Werner Arber was awarded the Nobel Prize in Physiology or Medicine in 1978 for his discovery of restriction enzymes and their appli- cation in molecular genetics together with the Americans Daniel Nathans and Hamilton Smith. He is one of the founding members of the Biozentrum, University of Basel, where he started as Professor of Molecular Microbiology in 1971. He also took on important leadership roles at the University of Basel, including Rektor, Dean of the Faculty of Science and Chairman of the Bio- zentrum. His scientific research contributed greatly to the internationally renowned reputation of the institute. Restriction enzymes, as molecular scissors, became available for today’s research in molecular genetics carried August 28, 2019, 4.00 – 5.30 pm out worldwide to obtain novel insights into the functions of living organisms. followed by an apéro This development paved also the way for various research areas at the Bio- Lecture Hall 1, Pharmazentrum, zentrum. On June 3, 2019, Werner Arber turned 90 years old. Klingelbergstrasse 50, Basel The Biozentrum invites you to a scientific symposium to celebrate the 90th birthday of Prof. em. Werner Arber, Nobel Prize Laureate 1978 and founding Program member of the Biozentrum, University of Basel. Welcome addresses Prof. Alex Schier Director of the Biozentrum, University of Basel Prof. Martin Jinek Prof. Andrea Schenker-Wicki President of the University of Basel Martin Jinek is an Associate Professor of Biochemistry at the University of Zurich. He studied Natural Sciences at Trinity College, University of Cam- The scientist Werner Arber bridge (UK). -
Daniel Nathans 1928–1999
NATIONAL ACADEMY OF SCIENCES DANIEL NATHANS 1928–1999 A Biographical Memoir by DANIEL DIMAIO Any opinions expressed in this memoir are those of the author and do not necessarily reflect the views of the National Academy of Sciences. Biographical Memoirs, VOLUME 79 PUBLISHED 2001 BY THE NATIONAL ACADEMY PRESS WASHINGTON, D.C. Photo by Arthur Kravetz, Baltimore, Maryland DANIEL NATHANS October 30, 1928–November 16, 1999 BY DANIEL DIMAIO ANIEL NATHANS, A SCIENTIST whose pioneering use of D restriction endonucleases revolutionized virology and genetics and whose personal qualities had a profound impact on those who knew him, passed away in November 1999 at the age of 71. He was the University Professor of Molecular Biology and Genetics at the Johns Hopkins University School of Medicine, where he served on the faculty for 37 years, and a senior investigator of the Howard Hughes Medical Institute since 1982. Dan is survived by his wife, Joanne; three sons, Eli, Jeremy, and Benjamin; and seven grand- children. Dan was born and raised in Wilmington, Delaware, the youngest of eight children of Russian Jewish immigrants. He attended the University of Delaware, initially living at home and commuting by hitchhiking, and graduated with a degree in chemistry in 1950. He then entered medical school at Washington University in St. Louis, largely because, he claimed, his father saw him “as the last chance to have a doctor in the family.” Dan began medical school with the intention of returning to Wilmington as a general practitioner, but a summer job in a local hospital bored him and made him rethink these plans and return early to St. -
INMUNOTERAPIA CONTRA EL CÁNCER ESPECIAL Inmunoterapia Contra El Cáncer
ESPECIAL INMUNOTERAPIA CONTRA EL CÁNCER ESPECIAL Inmunoterapia contra el cáncer CONTENIDO Una selección de nuestros mejores artículos sobre las distintas estrategias de inmunoterapia contra el cáncer. Las defensas contra el cáncer El científico paciente Karen Weintraub Katherine Harmon Investigación y Ciencia, junio 2016 Investigación y Ciencia, octubre 2012 Desactivar el cáncer Un interruptor Jedd D. Wolchok Investigación y Ciencia, julio 2014 para la terapia génica Jim Kozubek Investigación y Ciencia, mayo 2016 Una nueva arma contra el cáncer Viroterapia contra el cáncer Avery D. Posey Jr., Carl H. June y Bruce L. Levine Douglas J. Mahoney, David F. Stojdl y Gordon Laird Investigación y Ciencia, mayo 2017 Investigación y Ciencia, enero 2015 Vacunas contra el cáncer Inmunoterapia contra el cáncer Eric Von Hofe Lloyd J. Old Investigación y Ciencia, diciembre 2011 Investigación y Ciencia, noviembre 1996 EDITA Prensa Científica, S.A. Muntaner, 339 pral. 1a, 08021 Barcelona (España) [email protected] www.investigacionyciencia.es Copyright © Prensa Científica, S.A. y Scientific American, una división de Nature America, Inc. ESPECIAL n.o 36 ISSN: 2385-5657 En portada: iStock/royaltystockphoto | Imagen superior: iStock/man_at_mouse Takaaki Kajita Angus Deaton Paul Modrich Arthur B. McDonald Shuji Nakamura May-Britt Moser Edvard I. Moser Michael Levitt James E. Rothman Martin KarplusMÁS David DE J. 100 Wineland PREMIOS Serge Haroche NÓBEL J. B. Gurdon Adam G.han Riess explicado André K. Geim sus hallazgos Carol W. Greider en Jack W. Szostak E. H. Blackburn W. S. Boyle Yoichiro Nambu Luc MontagnierInvestigación Mario R. Capecchi y Ciencia Eric Maskin Roger D. Kornberg John Hall Theodor W. -
Francis Crick Personal Papers
http://oac.cdlib.org/findaid/ark:/13030/kt1k40250c No online items Francis Crick Personal Papers Special Collections & Archives, UC San Diego Special Collections & Archives, UC San Diego Copyright 2007, 2016 9500 Gilman Drive La Jolla 92093-0175 [email protected] URL: http://libraries.ucsd.edu/collections/sca/index.html Francis Crick Personal Papers MSS 0660 1 Descriptive Summary Languages: English Contributing Institution: Special Collections & Archives, UC San Diego 9500 Gilman Drive La Jolla 92093-0175 Title: Francis Crick Personal Papers Creator: Crick, Francis Identifier/Call Number: MSS 0660 Physical Description: 14.6 Linear feet(32 archives boxes, 4 card file boxes, 2 oversize folders, 4 map case folders, and digital files) Physical Description: 2.04 Gigabytes Date (inclusive): 1935-2007 Abstract: Personal papers of British scientist and Nobel Prize winner Francis Harry Compton Crick, who co-discovered the helical structure of DNA with James D. Watson. The papers document Crick's family, social and personal life from 1938 until his death in 2004, and include letters from friends and professional colleagues, family members and organizations. The papers also contain photographs of Crick and his circle; notebooks and numerous appointment books (1946-2004); writings of Crick and others; film and television projects; miscellaneous certificates and awards; materials relating to his wife, Odile Crick; and collected memorabilia. Scope and Content of Collection Personal papers of Francis Crick, the British molecular biologist, biophysicist, neuroscientist, and Nobel Prize winner who co-discovered the helical structure of DNA with James D. Watson. The papers provide a glimpse of his social life and relationships with family, friends and colleagues. -
A Glimpse of
A Glimpse of ... B HAKTIVEDANTA I NSTITUTE Kolkata Promoting dialogue between Science and Spirituality “Bhaktivedanta Institute is to be greatly congratulated for having produced so crucial and a productive discussion. It should be given every encouragement and support in going ahead with an enterprise so well begun.” — Prof. George Wald (Nobel Laureate in Physiology and Medicine) A Few Words of Appreciation ... I strongly believe that we all have divinity within ourselves. This divinity is the symbol of spiritualism. Integration of science and spiritualism helps us to balance ourselves. Therefore spiritualism is the key to Mental Health. My hearty congratulations to Bhaktivedanta Institute, Kolkata for their noble cause in imparting spiritual awareness in different parts of the country; to make this era spiritual in holistic manner. — Prof. Abha Singh Joint Director, Amity Institute of Behavioural and Allied Sciences, Noida, India Dear Dr. Singh, Today I had the fortune to meet Sri Jumukta Das and Sri Prasad Das (Volunteers in Motorhome) of your institute and to get myself apprised about the activities and programmes in which your divine institute is currently engaged. I was delighted to scan some of the publications of the institute and was very happy to note that the institute is engaged in creating a better understanding of science, religion and spirituality. ... We,at Delhi College of Engineering, shall be delighted to arrange your seminar at our institute so that the members of faculty and students of this premier institute could be benefited from interactions with you — Prof. P.B. Sharma Principal, Delhi College of Engineering, Delhi Prasad Das (Volunteer in Motorhome) delivered a lively lecture on science, spirituality and human values in this college. -
Le Scienze». Qui Presentiamo Estratti Dalle Pubblicazioni Del Nostro Archivio Che Hanno Gettato Nuova Luce Sul Funzionamento Del Corpo
RAPPORTO LINDAU BIOLOGIA Come funziona il corpo I vincitori di premi Nobel hanno pubblicato 245 articoli su «Scientific American», molti dei quali tradotti su «Le Scienze». Qui presentiamo estratti dalle pubblicazioni del nostro archivio che hanno gettato nuova luce sul funzionamento del corpo. È il nostro tributo agli scienziati che si riuniranno in Germania per il sessantaquattresimo Lindau Nobel Laureate Meeting, dove 600 giovani ricercatori scambieranno risultati e idee con 38 premi Nobel per la fisiologia o la medicina A cura di Ferris Jabr – Illustrazioni di Sam Falconer IN BREVE Questa estate i premi Nobel per la promettenti scienziati sull’isola di pubblichiamo una selezione di Gli estratti riguardano varie parti fisiologia o la medicina Lindau, in Germania. estratti di articoli sulla biologia dal del corpo, tra cui i muscoli, il cervello incontreranno centinaia di giovani Come tributo all’incontro, nostro archivio, firmati da Nobel. e il sistema immunitario. www.lescienze.it Le Scienze 41 RAPPORTO LINDAU Fisiologia di Edgar Douglas Adrian NEUROSCIENZE Pubblicazione: settembre 1950 Premio Nobel: 1932 Scopo della fisiologia è descrivere I meccanismi cerebrali movimento. Si trova così che sia la gli eventi che avvengono della visione cellula gangliare della retina sia la nell’organismo e, nel farlo, aiutare di David H. Hubel e cellula del corpo genicolato hanno incidentalmente il medico. Ma quali Torsten N. Wiesel la migliore risposta a una fonte eventi, e in quali termini dovrebbe NEUPubblicazioneRO su «LeS Scienze»:C IEluminosaNZE più o meno circolare, di descriverli? Al riguardo, nell’ultimo novembre 1979 un certo diametro, e posta in una mezzo secolo c’è stato un Premio Nobel: 1981 certa zona del campo visivo. -
Avant 12012 Online.Pdf
1 TRENDS IN INTERDISCIPLINARY STUDIES AVANT The Journal of the Philosophical-Interdisciplinary Vanguard AVANT Pismo awangardy filozoficzno-naukowej 1/2012 EDITORS OF THIS ISSUE / REDAKTORZY TEGO NUMERU Anna Karczmarczyk, Jakub R. Matyja, Jacek S. Podgórski, Witold Wachowski TORUŃ 3 ISSN: 2082-6710 AVANT. The Journal of the Philosophical-Interdisciplinary Vanguard AVANT. Pismo Awangardy Filozoficzno-Naukowej Vol. III, No. 1/2012, English Issue Toruń 2012 The texts are licensed under / Teksty udostępniono na licencji: CC BY-NC-ND 3.0, except for / z wyjątkiem: M. Rowlands: CC BY-NC 3.0, E. Cohen: special permission of the holders of the copyrights. Graphics design / Opracowanie graficzne: Karolina Pluta & Jacek S. Podgórski. Cover/Okładka: Surf & Mountain Range by / autorstwa: Monica Linville (front/przód: "Surf", Mixed Media on Panel, 8x10”; back/tył: "Mountain Range", Mixed Media on Panel, 8x10”). Pictures inside by / Fotografie wewnątrz autorstwa: Agnieszka Sroka. Address of the Editorial Office / Adres redakcji: skr. poczt. nr 34, U.P. Toruń 2. Filia, ul. Mazowiecka 63/65, 87-100 Toruń, Poland www.avant.edu.pl/en [email protected] Publisher / Wydawca: Ośrodek Badań Filozoficznych , ul. Stawki 3/20, 00-193 Warszawa, Poland www.obf.edu.pl Academic cooperation: university workers and PhD students of Nicolaus Copernicus University (Toruń, Poland). Współpraca naukowa: pracownicy i doktoranci Uniwersytetu Mikołaja Kopernika w Toruniu. The Journal has been registered in District Court in Warsaw, under number: PR 17724. Czasopismo zarejestrowano -
Finding the Tail End: the Discovery of RNA Splicing PROFILE Melissa Suran, Science Writer
PROFILE Finding the tail end: The discovery of RNA splicing PROFILE Melissa Suran, Science Writer Major findings are sometimes hidden in small details. Molecular biologists at the time worked almost At least that was the case when, in a PNAS article, exclusively with bacterial systems, which are easy to molecular biologist Phillip Sharp and his research grow in a laboratory. Although Sharp primarily studied team described a little strand of RNA that led to an bacteria and published work about the Escherichia coli understanding of how proteins are synthesized in genome during his postdoctoral position at the cells (1). California Institute of Technology with biochemist During the 1970s, Sharp headed a laboratory in the Norman Davidson (2, 3), he started exploring tumor Center for Cancer Research at the Massachusetts biology and virology. When Sharp arrived at CSHL, he turned his attention toward DNA viruses known to in- Institute of Technology (MIT). Having been a post- fect animal cells. He was particularly curious about doctoral researcher for geneticist James Watson and gene expression—the conversion of DNA into instruc- then a staff member at Cold Spring Harbor Laboratory tions for creating proteins—in human cells and began (CSHL) prior to his appointment at MIT, Sharp was studying the transcriptional profile of a simian DNA drawn to studying genes and measuring chromosome virus called SV40. Found in both humans and mon- sizes. The field of genetics was relatively primitive; keys, SV40 can generate tumors. Sharp’s work with Watson and Francis Crick had discovered DNA’s struc- the virus stemmed from a collaboration with virolo- ture only 2 decades earlier. -
Of Action of Anti-Erythrocyte Antibodies in a Murine Model of Immune Thrombocytopenia
Elucidating the Mechanism(s) of Action of Anti-Erythrocyte Antibodies in a Murine Model of Immune Thrombocytopenia by Ramsha Khan A thesis submitted in conformity with the requirements for the degree of Doctor of Philosophy Laboratory Medicine and Pathobiology University of Toronto © Copyright by Ramsha Khan 2021 Elucidating the Mechanism(s) of Action of Anti-Erythrocyte Antibodies in a Murine Model of Immune Thrombocytopenia Ramsha Khan Doctor of Philosophy Laboratory Medicine and Pathobiology University of Toronto 2021 Abstract Immune thrombocytopenia (ITP) is an autoimmune bleeding disorder that causes thrombocytopenia (decreased platelet numbers in the blood) primarily due to the presence of antiplatelet autoantibodies. Anti-D therapy (treatment with an antibody against the Rhesus-D factor on erythrocytes) has been proven to ameliorate ITP but as a human-derived product, it is limited in quantity and carries the potential risk of transferring emerging pathogens. Additionally, the US Food and Drug Administration has issued a black box warning for potentially serious adverse effects in ITP patients, including anemia, fever and/or chills. Therefore, there is incentive present for developing a safe and effective recombinant replacement that mimics the therapeutic activity of anti-D. Thus far, monoclonal anti-D antibodies have only had limited clinical success and better knowledge of its mechanism is required to accelerate the development of anti-D alternatives. This thesis documents studies that evaluated multiple anti- erythrocyte antibodies (as surrogates for anti-D) in murine models of ITP in order to provide insight regarding their mechanism(s) of action. Results indicate that adverse events such as anemia and temperature flux, which can be indicative of inflammatory activity, are not required for ITP amelioration; thus demonstrating that certain toxicities associated with anti-D therapy are independent of therapeutic activity and have the potential to be minimized when developing ii and/or screening synthetic alternatives.