INCI Nomenclature Conventions
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Brief Guide to the Nomenclature of Organic Chemistry
1 Brief Guide to the Nomenclature of Table 1: Components of the substitutive name Organic Chemistry (4S,5E)-4,6-dichlorohept-5-en-2-one for K.-H. Hellwich (Germany), R. M. Hartshorn (New Zealand), CH3 Cl O A. Yerin (Russia), T. Damhus (Denmark), A. T. Hutton (South 4 2 Africa). E-mail: [email protected] Sponsoring body: Cl 6 CH 5 3 IUPAC Division of Chemical Nomenclature and Structure suffix for principal hept(a) parent (heptane) one Representation. characteristic group en(e) unsaturation ending chloro substituent prefix 1 INTRODUCTION di multiplicative prefix S E stereodescriptors CHEMISTRY The universal adoption of an agreed nomenclature is a key tool for 2 4 5 6 locants ( ) enclosing marks efficient communication in the chemical sciences, in industry and Multiplicative prefixes (Table 2) are used when more than one for regulations associated with import/export or health and safety. fragment of a particular kind is present in a structure. Which kind of REPRESENTATION The International Union of Pure and Applied Chemistry (IUPAC) multiplicative prefix is used depends on the complexity of the provides recommendations on many aspects of nomenclature.1 The APPLIED corresponding fragment – e.g. trichloro, but tris(chloromethyl). basics of organic nomenclature are summarized here, and there are companion documents on the nomenclature of inorganic2 and Table 2: Multiplicative prefixes for simple/complicated entities polymer3 chemistry, with hyperlinks to original documents. An No. Simple Complicated No. Simple Complicated AND overall -
Minutes of the IUPAC Chemical Nomenclature and Structure Representation Division (VIII) Committee Meeting Boston, MA, USA, August 18, 2002
Minutes of the IUPAC Chemical Nomenclature and Structure Representation Division (VIII) Committee Meeting Boston, MA, USA, August 18, 2002 Members Present: Dr Stephen Heller, Prof Herbert Kaesz, Prof Dr Alexander Lawson, Prof G. Jeffrey Leigh, Dr Alan McNaught (President), Dr. Gerard Moss, Prof Bruce Novak, Dr Warren Powell (Secretary), Dr William Town, Dr Antony Williams Members Absent: Dr. Michael Dennis, Prof Michael Hess National representatives Present: Prof Roberto de Barros Faria (Brazil) The second meeting of the Division Committee of the IUPAC Division of Chemical Nomenclature and Structure Representation held in the Great Republic Room of the Westin Hotel in Boston, Massachusetts, USA was convened by President Alan McNaught at 9:00 a.m. on Sunday, August 18, 2002. 1.0 President McNaught welcomed the members to this meeting in Boston and offered a special welcome to the National Representative from Brazil, Prof Roberto de Barros Faria. He also noted that Dr Michael Dennis and Prof Michael Hess were unable to be with us. Each of the attendees introduced himself and provided a brief bit of background information. Housekeeping details regarding breaks and lunch were announced and an invitation to a reception from the U. S. National Committee for IUPAC on Tuesday, August 20 was noted. 2.0 The agenda as circulated was approved with the addition of a report from Dr Moss on the activity on his website. 3.0 The minutes of the Division Committee Meeting in Cambridge, UK, January 25, 2002 as posted on the Webboard (http://www.rsc.org/IUPAC8/attachments/MinutesDivCommJan2002.rtf and http://www.rsc.org/IUPAC8/attachments/MinutesDivCommJan2002.pdf) were approved with the following corrections: 3.1 The name Dr Gerard Moss should be added to the members present listing. -
( 12 ) United States Patent ( 10 ) Patent No .: US 10,751,310 B2 Freeman Et Al
US010751310B2 ( 12 ) United States Patent ( 10 ) Patent No .: US 10,751,310 B2 Freeman et al . ( 45 ) Date of Patent : Aug. 25 , 2020 ( 54 ) PREVENTION , TREATMENT AND ( 56 ) References Cited REVERSAL OF DISEASE USING THERAPEUTICALLY EFFECTIVE U.S. PATENT DOCUMENTS AMOUNTS OF DICARBOXYLIC ACID 3,527,789 A 9/1970 Payne COMPOUNDS 4,166,913 A 9/1979 Kesling , Jr. et al . 6,528,499 B1 * 3/2003 Kozikowski C07C 59/347 ( 71 ) Applicant: UNIVERSITY OF 514/574 8,324,277 B2 12/2012 Freeman PITTSBURGH — OF THE 8,735,449 B2 5/2014 Freeman COMMONWEALTH SYSTEM OF 9,066,902 B2 6/2015 Freeman et al . HIGHER EDUCATION , Pittsburgh , 9,186,408 B2 11/2015 Freeman et al . PA (US ) 9,700,534 B2 7/2017 Freeman et al . 9,750,725 B2 9/2017 Freeman et al . 10,213,417 B2 2/2019 Freeman et al . ( 72 ) Inventors : Bruce A. Freeman , Pittsburgh , PA 10,258,589 B2 4/2019 Freeman et al . ( US ) ; Francisco J. Schopfer , 2015/0018417 Al 1/2015 Freeman et al . Pittsburgh , PA ( US ) FOREIGN PATENT DOCUMENTS ( 73 ) Assignee : University of Pittsburgh — of the CN 103705499 4/2014 Commonwealth System of Higher DE 102011118462 5/2013 Education , Pittsburgh , PA ( US ) GB 1153464 5/1969 WO WO 2002/022627 3/2002 WO WO 2009/017802 2/2009 ( * ) Notice : Subject to any disclaimer , the term of this WO WO 2009/112455 9/2009 patent is extended or adjusted under 35 WO WO 2010/005521 1/2010 U.S.C. 154 ( b ) by 0 days . WO WO 2010/014889 2/2010 WO WO 2011/014261 2/2011 WO WO 2013/116753 8/2013 ( 21 ) Appl. -
Production of Butanol by Clostridium Acetobutyucum in Extractive Fermentation System
PRODUCTION OF BUTANOL BY CLOSTRIDIUM ACETOBUTYUCUM IN EXTRACTIVE FERMENTATION SYSTEM Shigeo ISHII, Masahito TAYA and Takeshi KOBAYASHI Department of Chemical Engineering, Faculty of Engineering, Nagoya University, Nagoya 464 Key Words: Biochemical Engineering, Extractive Fermentation, Butanol Production, Aliphatic Alcohol, Clostridium acetobutylicum Anextractive fermentation system was developed to prevent end-product inhibition of Clostridium aceto- butylicum IAM 19012, which mainly produces butanol and acetone. Butanol exhibited greater toxicity to the microorganism than acetone, and its growth was completely inhibited above 10 kg/m3 of butanol. As an extracting solvent suitable for acetone-butanol fermentation, oleyl alcohol (cw-9-octadecen-l-ol) and C-20 guerbet alcohol (branched-chain alcohol of carbon number, 20) were selected from among29 organic compounds, based on their nontoxicity to the microorganism. These two solvents had high partition coefficients for butanol, and could be reused without deterioration. In fermentation with the solvent (solvent phase : aqueous phase=2 : 5 (v/v)), the viability of the microorganism was resumed by the liquid-liquid extraction of butanol from the broth, and the amount of butanol produced was 2.6 times that in fermentation without extraction. tation by liquid-liquid extraction. To date, a few Intr oduction studies on extractive fermentation have been carried Microbial production of acetone and butanol is a out for ethanol fermentation by yeast.5'10'18) traditional fermentation process. After World War II, The aim of the present study is to develop a new however, the fermentation process for acetone- strategy which combines both physical liquid-liquid butanol production was superseded by chemical extraction and biological fermentation processes, and synthetic processes using petroleum-based feed- furthermore to achieve improved production of bu- stocks, except for a fermentation plant in South Africa.15) tanol and acetone by extractive fermentation. -
Listed Below Are All of the Revised Titles in the Description and Solubility Reference Table of USP 36-NF 31 Second Supplement
Listed below are all of the revised titles in the Description and Solubility reference table of USP 36-NF 31 Second Supplement. For additional information please see general information chapter Excipient Performance <1059> and USP and NF Excipients, Listed by Functional Category, published in the USP 36- NF 31 Second Supplement. Acacia Carbomer Interpolymer Acetic Acid Carbon Dioxide Glacial Acetic Acid Carboxymethylcellulose Calcium Adipic Acid Carboxymethylcellulose Sodium Agar Enzymatically-Hydrolyzed Alcohol Carboxymethylcellulose Sodium Alfadex Carmellose Alginic Acid Carrageenan Almond Oil Castor Oil Aluminum Monostearate Hydrogenated Castor Oil Aluminum Oxide Cellaburate Amino Methacrylate Copolymer Cellacefate Aminobenzoic Acid Cellulose Acetate Strong Ammonia Solution Microcrystalline Cellulose Ammonio Methacrylate Copolymer Silicified Microcrystalline Cellulose Ammonio Methacrylate Copolymer Dispersion Powdered Cellulose Ammonium Carbonate Cetostearyl Alcohol Ammonium Chloride Cetyl Alcohol Ammonium Phosphate Cetyl Esters Wax Anethole Cetylpyridinium Chloride Behenoyl Polyoxylglycerides Chlorobutanol Benzaldehyde Chloroxylenol Benzalkonium Chloride Cholesterol Benzyl Alcohol Anhydrous Citric Acid Benzyl Benzoate Citric Acid Monohydrate Betadex Coconut Oil Betadex Sulfobutyl Ether Sodium Hydrogenated Coconut Oil Boric Acid Copovidone Butane Corn Syrup Calcium Acetate Corn Syrup Solids Calcium Carbonate Creatinine Calcium Chloride Croscarmellose Sodium Calcium Hydroxide Crospovidone Calcium Lactate Denatonium Benzoate Dibasic -
Official Journal of the European Communities on the Hygiene Of
No L 21 /42 EN Official Journal of the European Communities 27 . 1 . 96 COMMISSION DIRECTIVE 96/3/EC of 26 January 1 996 granting a derogation from certain provisions of Council Directive 93/43/EEC on the hygiene of foodstuffs as regards the transport of bulk liquid oils and fats by sea (Text with EEA relevance) THE COMMISSION OF THE EUROPEAN COMMUNITIES, whereas the measures provided for in this Directive are in compliance with the opinion of the Standing Having regard to the Treaty establishing the European Committee for Foodstuffs, Community, Having regard to Council Directive 93/43/EEC of 14 June 1993 on the hygiene of foodstuffs ('), and in parti HAS ADOPTED THIS DIRECTIVE : cular Article 3 (3) thereof, Whereas information shows that the application of the second subparagraph of paragraph 2 of Chapter IV of the Article 1 Annex to Directive 93/43/EEC relating to the transport of bulk foodstuffs in liquid, granulate or powdered form in This Directive derogates from the second subparagraph of receptacles and/or containers/tankers reserved for the paragraph 2 of Chapter IV of the Annex to Directive transport of foodstuffs, is not practical and imposes an 93/43/EEC and lays down equivalent conditions to ensure unduly onerous burden on food business when applied to the protection of public health and the safety and whole the transport in sea-going vessels of liquid oils and fats someness of the foodstuffs concerned . intended for, or likely to be used for, human consump tion ; Article 2 Whereas, however, it is necessary to ensure that the granting of a derogation provides equivalent protection to public health, by attaching conditions to the terms of 1 . -
Hexanol Biosynthesis from Syngas by Clostridium Carboxidivorans P7 Is Enhanced by In‑Line Extraction with a Biocompatible Solvent to Avoid Product Toxicity
Hexanol biosynthesis from syngas by Clostridium carboxidivorans P7 is enhanced by in‐line extraction with a biocompatible solvent to avoid product toxicity Patrick Kottenhahn Fraunhofer-Institut fur Molekularbiologie und Angewandte Oekologie Gabriele Philipps Fraunhofer-Institut fur Molekularbiologie und Angewandte Oekologie Stefan Jennewein ( [email protected] ) Fraunhofer-Institut fur Molekularbiologie und Angewandte Oekologie https://orcid.org/0000-0002- 1625-5484 Research Keywords: oleyl alcohol, product toxicity, bioeconomy, carbon xation, C1 compounds, Clostridium ljungdahlii, in situ extraction, biofuels Posted Date: February 18th, 2020 DOI: https://doi.org/10.21203/rs.2.23824/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/17 Abstract Background Clostridium carboxidivorans P7 has the rare ability to metabolize syngas – a mixture of H2, CO and CO2 – by converting it directly into industrially relevant alcohols (hexanol, butanol and ethanol) and the corresponding acids (caproate, butyrate and acetate). The product titers and ratios are highly dependent on the fermentation parameters and the composition of the syngas and growth medium. The hexanol titers produced by C. carboxidivorans P7 have recently been improved by optimizing these conditions, but little is known about the toxicity of hexanol towards Clostridium species. We hypothesized that the hexanol titers currently produced by C. carboxidivorans P7 are limited by product toxicity. Results We tested our hypothesis by exposing C. carboxidivorans P7 to different concentrations of hexanol and found that growth inhibition started at 10–12 mM, with an IC50 of 17.5 ± 1.6 mM. The presence of 20 mM hexanol was acutely toxic to C. -
Dialogue on the Nomenclature and Classification of Prokaryotes
G Model SYAPM-25929; No. of Pages 10 ARTICLE IN PRESS Systematic and Applied Microbiology xxx (2018) xxx–xxx Contents lists available at ScienceDirect Systematic and Applied Microbiology journal homepage: www.elsevier.de/syapm Dialogue on the nomenclature and classification of prokaryotes a,∗ b Ramon Rosselló-Móra , William B. Whitman a Marine Microbiology Group, IMEDEA (CSIC-UIB), 07190 Esporles, Spain b Department of Microbiology, University of Georgia, Athens, GA 30602, USA a r t i c l e i n f o a b s t r a c t Keywords: The application of next generation sequencing and molecular ecology to the systematics and taxonomy Bacteriological code of prokaryotes offers enormous insights into prokaryotic biology. This discussion explores some major Taxonomy disagreements but also considers the opportunities associated with the nomenclature of the uncultured Nomenclature taxa, the use of genome sequences as type material, the plurality of the nomenclatural code, and the roles Candidatus of an official or computer-assisted taxonomy. Type material © 2018 Elsevier GmbH. All rights reserved. Is naming important when defined here as providing labels Prior to the 1980s, one of the major functions of Bergey’s Manual for biological entities? was to associate the multiple names in current usage with the cor- rect organism. For instance, in the 1948 edition of the Manual, 21 Whitman and 33 names were associated with the common bacterial species now named Escherichia coli and Bacillus subtilis, respectively [5]. When discussing the nomenclature of prokaryotes, we must first This experience illustrates that without a naming system gener- establish the role and importance of naming. -
ACRONYM & GLOSSARY LIST - Revised 9/2008
Survey & Certification Emergency Preparedness Initiative – All Hazards EMERGENCY PREPAREDNESS ACRONYM & GLOSSARY LIST - Revised 9/2008 ACRONYMS AAL Authorized Access List AAR After-Action Report ACE Army Corps of Engineers ACIP Advisory Committee on Immunization Practices ACL Access Control List ACLS Advanced Cardiac Life Support ACF Administration for Children and Families (HHS) ACS Alternate Care Site ADP Automated Data Processing AFE Annual Frequency Estimate AHRQ Agency for Healthcare Research and Quality (HHS) AIE Annual Impact Estimate AIS Automated Information System AISSP Automated Information Systems Security Program AMSC American Satellite Communications ANG Air National Guard ANSI American National Standards Institute AO Accrediting Organization AoA Administration on Aging (HHS) APE Assistant Secretary for Planning and Evaluation (HHS) APF Authorized Program Facility APHL Association of Public Health Laboratories ARC American Red Cross ARES Amateur Radio Emergency Service ARF Agency Request Form ARO Annualized Rate of Occurrence ASAM Assistant Secretary for Administration & Management (HHS) ASC Ambulatory Surgical Center ASC Accredited Standards Committee ASH Assistant Secretary for Health (HHS) ASL Assistant Secretary for Legislation (HHS) ASPA Assistant Secretary for Public Affairs (HHS) ASPE Assistant Secretary for Planning & Evaluation (HHS) ASPR Assistant Secretary for Preparedness & Response (HHS) ASRT Assistant Secretary for Resources & Technology (HHS) ATSDR Agency for Toxic Substances & Disease Registry (HHS) BARDA -
Principles for the Consistent Use of Place Names
Principles for the Consistent Use of Place Names includes Principles for the Use of Aboriginal and Torres Strait Islander Place Names and Dual Naming Depiction Principles Permanent Committee on Place Names Edition History March 2009 June 2009 September 2011 April 2012 September 2012 April 2014 Corrections to cross-references, p.10 (4.23) and p.17 (Item 1). May 2014 Web-link updated (p. 5); minor revisions to style and usage. March 2015 Revisions to 4.6, 4.8 (added), 4.14, 4.20, 4.23, 4.26, 4.27 (added), 4.28 (added) December 2015 Update to Committee names and style; 4.19 revised This Edition: October 2016 New title to the document; terms of reference statement updated; 4.19 revised 2 TABLE OF CONTENTS PRINCIPLES FOR THE CONSISTENT USE OF PLACE NAMES ...................................... 5 1 Introduction .................................................................................................................... 5 2 Place Names Authorities ............................................................................................... 6 3 Permanent Committee on Place Names ....................................................................... 6 4 Guidelines ...................................................................................................................... 7 4.1 Official Language .................................................................................................... 7 4.2 Names Governed by Statutory or Administrative Authority ..................................... 7 4.3 Official or Approved Names -
OLEYL ALCOHOL Alcohol Oleicus OLIVE LEAF Oleae Folium
Oleyl alcohol EUROPEAN PHARMACOPOEIA 5.0 — arachidic acid: not more than 2.0 per cent, Composition of fatty alcohols. Gas chromatography — eicosenoic acid:notmorethan2.0percent. (2.2.28): use the normalisation procedure. Ethylene oxide and dioxan (2.4.25). Not more than 1 ppm Test solution. Mix 25 mg of the substance to be examined of ethylene oxide and 10 ppm of dioxan. with 1.0 ml of methylene chloride R. Heavy metals (2.4.8). 2.0 g complies with limit test C for Reference solution (a). Dissolve 25 mg of each of arachidyl heavy metals (10 ppm). Prepare the standard using 2 ml of alcohol R, linolenyl alcohol R, linoleyl alcohol R, oleyl lead standard solution (10 ppm Pb) R. alcohol R, palmityl alcohol R and stearyl alcohol R in methylene chloride R and dilute to 5 ml with the same Water (2.5.12). Not more than 1.0 per cent, determined solvent. Dilute 1 ml of this solution to 5 ml with methylene on 1.0 g by the semi-micro determination of water. Use chloride R. amixtureof30volumesofanhydrous methanol R and Reference solution (b). Dissolve 10 mg of linoleyl alcohol R 70 volumes of methylene chloride R as solvent. and 1 g of oleyl alcohol R in methylenechlorideRand Total ash (2.4.16). Not more than 0.1 per cent, determined dilute to 40 ml with the same solvent. on 1.0 g. Column: STORAGE — size: l =30m,Ø=0.32mm, Store protected from light and at room temperature. — stationary phase: poly(dimethyl)siloxane R (film thickness 1 µm). -
Oleyl Alcohol
Oleyl alcohol Product Number O 8880 Storage Temperature -0 °C Product Description Precautions and Disclaimer Molecular Formula: C18H36O For Laboratory Use Only. Not for drug, household or Molecular Weight: 268.5 other uses. CAS Number: 143-28-2 Density: 0.850 g/ml (20 °C)1 Preparation Instructions Melting Point: 13-19 °C1 This product is miscible in chloroform (0.1 ml/ml, v/v), Synonyms: (Z)-9-octadecen-1-ol, yielding a clear, colorless solution. It is also miscible 1 cis-9-octadecen-1-ol, ocenol1 in alcohol and ether. This product is prepared by synthetic reduction of References plant-derived oleic acid. 1. The Merck Index, 12th ed., Entry# 6968. 2. Lee, P. J., et al., Novel microemulsion enhancer Oleyl alcohol is a long-chain aliphatic alcohol that formulation for simultaneous transdermal delivery occurs naturally in fish oils. It is used in such large- of hydrophilic and hydrophobic drugs. Pharm. scale applications as the softening and lubrication of Res., 20(2), 264-269 (2003). textile fabrics, and the production of carbon paper, 3. Sudimack, J. J., et al., A novel pH-sensitive stencil paper, and printing ink. Oleyl alcohol is also liposome formulation containing oleyl alcohol. utilized as an antifoam agent and cutting lubricant. It Biochim. Biophys. Acta., 1564(1), 31-37 (2002). also is a precursor for the preparation of its sulfuric 4. Tsujita, T., et al., Regulation of carboxylester ester derivatives, which are used in detergents and lipase adsorption to surfaces. 2. Physical state wetting agents.1 specificity. Biochemistry. 1987 Dec 15;26(25):8430-8434 (1987).