Anti-GFM2 (Aa 436-612) Polyclonal Antibody (DPABH-12102) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-GFM2 (aa 436-612) polyclonal antibody (DPABH-12102) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.

Immunogen Recombinant fragment corresponding to Human GFM2 aa 436-612. (BC015712)Sequence: VGLKHTATGDTIVSSKSSALAAARRAEREGEKKHRQNNEAERLLLAGVEI PEPVFFCTIEPPSLSKQPDLEHALKCLQREDPSLKVRLDPDSGQTVLCGM GELHIEIIHDRIKREYGLETYLGPLQVAYRETILNSVRATDTLDRTLGDK RHLVTVEVEARPIETSSVMPV

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications IHC-P, WB

Format Liquid

Size 100 μg

Buffer pH: 7.20; Constituents: 98% PBS, 1% BSA

Preservative 0.02% Sodium Azide

Storage Shipped at 4°C. Store at 4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Gene Name GFM2 G elongation factor, mitochondrial 2 [ Homo sapiens ]

Official Symbol GFM2

Synonyms GFM2; G elongation factor, mitochondrial 2; ribosome-releasing factor 2, mitochondrial; EFG2; FLJ21661; MSTP027; mitochondrial elongation factor G2; elongation factor G 2, mitochondrial; mitochondrial ribosome recycling factor 2; RRF2; MRRF2; hEFG2; MST027; RRF2mt; EF-G2mt; mEF-G 2;

Entrez Gene ID 84340

Protein Refseq NP_115756

UniProt ID Q969S9

Chromosome Location 5q13

Function GTP binding; GTPase activity; nucleotide binding; NOT translation elongation factor activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]