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Journal of Autoimmunity xxx (xxxx) xxxx Contents lists available at ScienceDirect Journal of Autoimmunity journal homepage: www.elsevier.com/locate/jautimm Review article The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China ∗∗∗∗ Yongshi Yanga,1, Fujun Pengb,c,1, Runsheng Wangd,1, Kai Guana, Taijiao Jiangb,c, , ∗∗∗ ∗∗ ∗ Guogang Xue, , Jinlyu Suna, , Christopher Changf,g, a Department of Allergy & Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, National Clinical Research Center for Immunologic Diseases, Beijing, 100730, China b Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China c Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China d Department of Respiratory Diseases, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, China e Department of Infection Prevention and Disease Control, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, China f Division of Rheumatology, Allergy and Clinical Immunology, University of California, Davis, Davis, CA, 95616, USA g Division of Pediatric Immunology and Allergy, Joe DiMaggio Children's Hospital, Hollywood, FL, USA ARTICLE INFO ABSTRACT Keywords: The 2019-nCoV is officially called SARS-CoV-2 and the disease is named COVID-19. This viral epidemic inChina Coronavirus has led to the deaths of over 1800 people, mostly elderly or those with an underlying chronic disease or im- SARS-CoV-2 munosuppressed state. This is the third serious Coronavirus outbreak in less than 20 years, following SARS in SARS-CoV 2002–2003 and MERS in 2012.
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