Sexually Transmitted Infections (Stis)
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Expanding the Role of Dermatology at the World Health Organization and Beyond
EDITORIAL A Seat at the Big Table: Expanding the Role of Dermatology at the World Health Organization and Beyond y patient can’t breathe. From across Kaposi’s sarcoma, seborrheic dermatitis, her- the busy, open ward, you can see the pes zoster, scabies, papular pruritic eruption, Mplaques of Kaposi’s sarcoma riddling eosinophilic folliculitis, tinea, molluscum, drug her skin. The impressive woody edema has reactions, and oral candidiasis (World Health enlarged her legs to the size of small tree trunks. Organization, in press). These conditions have We don’t have access to confirmatory pulmo- a high prevalence in developing countries, but nary testing in Kenya, but she probably wouldn’t many lack internationally agreed-on standards survive a bronchoscopy anyway. of care. This deficit led to inconsistent and some- When she dies six hours later, we can be pret- times dangerous treatment approaches or lack of ty sure that it is her pulmonary Kaposi’s sarcoma, essential drugs. Critically, dermatologists were along with her underlying HIV, that killed her. involved at all levels of the guideline-develop- Her family tells us that she had dark spots on ment process, including Cochrane reviews of the her skin and swelling in her legs for more than literature, guideline development and review, a year before she presented to the hospital. Like and additional funding for the project from many of our patients in East Africa, she sought the International Foundation for Dermatology help from a traditional healer for many months (http://www.ifd.org). before turning to the biomedical health system, Although diseases such as Kaposi’s sarcoma only hours before her death. -
Skin Cancer in the Immunocompromised Patient
Dermatologic Risks and Transplantation Allison Hanlon, MD, PhD Vanderbilt University School of Medicine Department of Medicine Division of Dermatology I have no relevant conflicts of interest to disclose. Dermatologic Risks and Transplantation • Acne • Folliculitis • Sebaceous hyperplasia • Overgrowth of hair • Infections – warts, molluscum contagiosum • Skin thinning and increased bruising • Skin cancer Folliculitis and Acne Folliculitis Sebaceous Hyperplasia Overgrowth of Hair Cyclosporine associated Gingival Hyperplasis Molluscum Contagiosum Verruca Easy Bruising and Skin Thinning Overview of Skin Cancer in SOTR • Clinical appearance of most common skin cancers • Risk factors for developing skin cancer • Skin cancer prevention • Multidisciplinary care Basal Cell Carcinoma Basal Cell Carcinoma Nodular Basal Cell Carcinoma Basal Cell Carcinoma Squamous Cell Carcinoma Squamous Cell Carcinoma Field Cancerization Immunocompromised patients at risk for metastasis Melanoma Nail Unit Melanoma Nodular Melanoma Melanoma Benign Seborrheic Keratosis Skin cancer is the most common malignancy in solid organ transplant recipients • Skin cancer accounts for 40% of malignancies in solid organ transplant recipients (SOTR) • 50% of Caucasian SOTR will develop skin cancer • Non-melanoma skin cancer (NMSC) > melanoma Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med 2003;348:1681 Skin Cancer in SOTR • Squamous cell carcinoma (SCC) is the most common cutaneous malignancy in transplant patient • Basal cell carcinoma (BCC) is second most common skin cancer in transplant patient • Melanoma risk 3.6 times greater likelihood in SOTR Hollenbeak CS et al. Cancer 2005; 104:1962 than the general Euvrard S et.al. N Engl J Med 2003;348:1681 population Lanov E et.al. Int J Cancer. 2010;126:1724 Proposed Mechanisms Of Immunosuppression relationship to Skin Cancer Development • Direct carcinogenic effects of immunosuppression medications • Proliferation of oncogenic viruses • Reduced immune surveillance within transplant skin cancers Carucci et.al.PLoS One. -
Molluscum Contagiosum
Partners in Pediatrics, PC 7110 Forest Ave Suite 105 Richmond, VA 23226 804-377-7100 Molluscum Contagiosum Although molluscum contagiosum is a common skin rash in kids, many parents have never heard of it. The most important thing to know about it is that, for most children, the rash is no big deal and goes away on its own over time. About Molluscum Contagiosum Molluscum contagiosum is a viral infection that causes a mild skin rash. The rash looks like one or more small growths or wart-like bumps (called mollusca) that are usually pink, white, or skin-colored. The bumps are usually soft and smooth and may have an indented center. Infection is most common among kids between 1 and 12 years old, but also occurs in: teens and adults some athletes, such as wrestlers, swimmers, and gymnasts people whose immune systems have been weakened by HIV, cancer treatment, or long-term steroid use As you might guess by its name, this skin disorder is contagious, and can be passed from one person to another. It is unknown how long the rash and virus may be contagious. Causes Molluscum contagiosum is caused by the molluscum contagiosum virus (MCV), a member of the poxvirus family. This virus thrives in warm, humid climates and in areas where people live very close together. Infection with MCV occurs when the virus enters a small break in the skin's surface. Many people who come in contact with the virus have immunity against it, and do not develop any growths. For those not resistant to it, growths usually appear 2 to 8 weeks after infection. -
Cutaneous Manifestations of HIV Infection Carrie L
Chapter Title Cutaneous Manifestations of HIV Infection Carrie L. Kovarik, MD Addy Kekitiinwa, MB, ChB Heidi Schwarzwald, MD, MPH Objectives Table 1. Cutaneous manifestations of HIV 1. Review the most common cutaneous Cause Manifestations manifestations of human immunodeficiency Neoplasia Kaposi sarcoma virus (HIV) infection. Lymphoma 2. Describe the methods of diagnosis and treatment Squamous cell carcinoma for each cutaneous disease. Infectious Herpes zoster Herpes simplex virus infections Superficial fungal infections Key Points Angular cheilitis 1. Cutaneous lesions are often the first Chancroid manifestation of HIV noted by patients and Cryptococcus Histoplasmosis health professionals. Human papillomavirus (verruca vulgaris, 2. Cutaneous lesions occur frequently in both adults verruca plana, condyloma) and children infected with HIV. Impetigo 3. Diagnosis of several mucocutaneous diseases Lymphogranuloma venereum in the setting of HIV will allow appropriate Molluscum contagiosum treatment and prevention of complications. Syphilis Furunculosis 4. Prompt diagnosis and treatment of cutaneous Folliculitis manifestations can prevent complications and Pyomyositis improve quality of life for HIV-infected persons. Other Pruritic papular eruption Seborrheic dermatitis Overview Drug eruption Vasculitis Many people with human immunodeficiency virus Psoriasis (HIV) infection develop cutaneous lesions. The risk of Hyperpigmentation developing cutaneous manifestations increases with Photodermatitis disease progression. As immunosuppression increases, Atopic Dermatitis patients may develop multiple skin diseases at once, Hair changes atypical-appearing skin lesions, or diseases that are refractory to standard treatment. Skin conditions that have been associated with HIV infection are listed in Clinical staging is useful in the initial assessment of a Table 1. patient, at the time the patient enters into long-term HIV care, and for monitoring a patient’s disease progression. -
WHO GUIDELINES for the Treatment of Treponema Pallidum (Syphilis)
WHO GUIDELINES FOR THE Treatment of Treponema pallidum (syphilis) WHO GUIDELINES FOR THE Treatment of Treponema pallidum (syphilis) WHO Library Cataloguing-in-Publication Data WHO guidelines for the treatment of Treponema pallidum (syphilis). Contents: Web annex D: Evidence profiles and evidence-to-decision frameworks - Web annex E: Systematic reviews for syphilis guidelines - Web annex F: Summary of conflicts of interest 1.Syphilis – drug therapy. 2.Treponema pallidum. 3.Sexually Transmitted Diseases. 4.Guideline. I.World Health Organization. ISBN 978 92 4 154980 6 (NLM classification: WC 170) © World Health Organization 2016 All rights reserved. Publications of the World Health Organization are available on the WHO website (http://www.who.int) or can be purchased from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel.: +41 22 791 3264; fax: +41 22 791 4857; email: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for non-commercial distribution– should be addressed to WHO Press through the WHO website (http://www.who.int/about/licensing/ copyright_form/index.html). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted and dashed lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. -
Eyelid Conjunctival Tumors
EYELID &CONJUNCTIVAL TUMORS PHOTOGRAPHIC ATLAS Dr. Olivier Galatoire Dr. Christine Levy-Gabriel Dr. Mathieu Zmuda EYELID & CONJUNCTIVAL TUMORS 4 EYELID & CONJUNCTIVAL TUMORS Dear readers, All rights of translation, adaptation, or reproduction by any means are reserved in all countries. The reproduction or representation, in whole or in part and by any means, of any of the pages published in the present book without the prior written consent of the publisher, is prohibited and illegal and would constitute an infringement. Only reproductions strictly reserved for the private use of the copier and not intended for collective use, and short analyses and quotations justified by the illustrative or scientific nature of the work in which they are incorporated, are authorized (Law of March 11, 1957 art. 40 and 41 and Criminal Code art. 425). EYELID & CONJUNCTIVAL TUMORS EYELID & CONJUNCTIVAL TUMORS 5 6 EYELID & CONJUNCTIVAL TUMORS Foreword Dr. Serge Morax I am honored to introduce this Photographic Atlas of palpebral and conjunctival tumors,which is the culmination of the close collaboration between Drs. Olivier Galatoire and Mathieu Zmuda of the A. de Rothschild Ophthalmological Foundation and Dr. Christine Levy-Gabriel of the Curie Institute. The subject is now of unquestionable importance and evidently of great interest to Ophthalmologists, whether they are orbital- palpebral specialists or not. Indeed, errors or delays in the diagnosis of tumor pathologies are relatively common and the consequences can be serious in the case of malignant tumors, especially carcinomas. Swift diagnosis and anatomopathological confirmation will lead to a treatment, discussed in multidisciplinary team meetings, ranging from surgery to radiotherapy. -
Genital Herpes
Genital herpes FACT SHEET Summary Published Genital herpes is a sexually transmitted infection caused by the 2016 herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). Once a person is infected with HSV, the virus stays in the body for life. Both HSV-1 and HSV-2 can be transmitted through sexual contact. Genital herpes is an HSV infection of the groin, pubic CONTACT US area, genital area, anus, rectum or buttocks. by telephone 1-800-263-1638 All people who are sexually active may be at risk for 416-203-7122 genital herpes. by fax Many people with genital herpes have no symptoms or the 416-203-8284 symptoms are very mild so they go unnoticed or are mistaken for another skin condition. The most common symptoms of by e-mail genital herpes are lesions, which appear as painful blisters in [email protected] the genital area. by mail 555 Richmond Street West To test for genital herpes, samples are taken from the sites of Suite 505, Box 1104 suspected infection and tested for the presence of the virus. Toronto ON M5V 3B1 Blood tests can also be used to determine if HSV-1 or HSV-2 is present in the body. Antiviral medications can reduce the severity and frequency of genital herpes outbreaks. Genital herpes increases the risk of HIV transmission. Correct and consistent condom use and antiviral medication can reduce the risk of genital herpes transmission. Key messages on genital herpes for clients are available at the end of this fact sheet. The words we use here – CATIE is committed to using language that is relevant to everyone. -
Herpes: a Patient's Guide
Herpes: A Patient’s Guide Herpes: A Patient’s Guide Introduction Herpes is a very common infection that is passed through HSV-1 and HSV-2: what’s in a name? ....................................................................3 skin-to-skin contact. Canadian studies have estimated that up to 89% of Canadians have been exposed to herpes simplex Herpes symptoms .........................................................................................................4 type 1 (HSV-1), which usually shows up as cold sores on the Herpes transmission: how do you get herpes? ................................................6 mouth. In a British Columbia study, about 15% of people tested positive for herpes simplex type 2 (HSV-2), which Herpes testing: when is it useful? ..........................................................................8 is the type of herpes most commonly thought of as genital herpes. Recently, HSV-1 has been showing up more and Herpes treatment: managing your symptoms ...................................................10 more on the genitals. Some people can have both types of What does herpes mean to you: receiving a new diagnosis ......................12 herpes. Most people have such minor symptoms that they don’t even know they have herpes. What does herpes mean to you: accepting your diagnosis ........................14 While herpes is very common, it also carries a lot of stigma. What does herpes mean to you: dating with herpes ....................................16 This stigma can lead to anxiety, fear and misinformation -
HIV Infection and AIDS
G Maartens 12 HIV infection and AIDS Clinical examination in HIV disease 306 Prevention of opportunistic infections 323 Epidemiology 308 Preventing exposure 323 Global and regional epidemics 308 Chemoprophylaxis 323 Modes of transmission 308 Immunisation 324 Virology and immunology 309 Antiretroviral therapy 324 ART complications 325 Diagnosis and investigations 310 ART in special situations 326 Diagnosing HIV infection 310 Prevention of HIV 327 Viral load and CD4 counts 311 Clinical manifestations of HIV 311 Presenting problems in HIV infection 312 Lymphadenopathy 313 Weight loss 313 Fever 313 Mucocutaneous disease 314 Gastrointestinal disease 316 Hepatobiliary disease 317 Respiratory disease 318 Nervous system and eye disease 319 Rheumatological disease 321 Haematological abnormalities 322 Renal disease 322 Cardiac disease 322 HIV-related cancers 322 306 • HIV INFECTION AND AIDS Clinical examination in HIV disease 2 Oropharynx 34Neck Eyes Mucous membranes Lymph node enlargement Retina Tuberculosis Toxoplasmosis Lymphoma HIV retinopathy Kaposi’s sarcoma Progressive outer retinal Persistent generalised necrosis lymphadenopathy Parotidomegaly Oropharyngeal candidiasis Cytomegalovirus retinitis Cervical lymphadenopathy 3 Oral hairy leucoplakia 5 Central nervous system Herpes simplex Higher mental function Aphthous ulcers 4 HIV dementia Kaposi’s sarcoma Progressive multifocal leucoencephalopathy Teeth Focal signs 5 Toxoplasmosis Primary CNS lymphoma Neck stiffness Cryptococcal meningitis 2 Tuberculous meningitis Pneumococcal meningitis 6 -
Pedianews Volume VI, Issue II the Official Newsletter of the Student Society of Pediatric Advocates (Rxpups) May 2018
1 PediaNews Volume VI, Issue II The Official Newsletter of the Student Society of Pediatric Advocates (RxPups) May 2018 Inside this issue LICEnse to Kill LICEnse to Kill ................... 1-2 Written by: Kirty Patel, Pharm.D. Candidate 2020 Pediatric Idiopathic Thrombocytopenia Purpura ................................. 3-5 It is a dreadful feeling of anxiety when any parent, teacher, or Obesity in Children .......... 6-8 other caregiver discovers lice in a child’s hair. They begin to look back on the past few days and realize that the child has been scratching their Editors head frequently, which is a common sign of head lice. The itching is caused by an allergic reaction to louse saliva. The caregiver may wonder Linda Logan, Pharm.D., BCPS, BCACP why they didn’t previously notice the symptoms but know they can Faculty Advisor contact their local pharmacist with questions, concerns, and guidance Alicia Sanchez, Pharm.D., for the treatment process. PGY2 Pediatric Pharmacy Upon obtaining the phone call, the pharmacist wants to confirm Resident that the child does in fact have lice. The pharmacist explains to the Namita Patel, PharmD caregiver that although lice are small, they can be detected by the Candidate Class of 2019 University of Georgia naked eye. The best way to detect a child’s current state of infestation College of Pharmacy is to examine their scalp for nits (lice eggs) using a magnifying lens and a toothpick comb. Empty nits are lighter in color and further from the scalp, but do not necessarily indicate an active infiltration of lice.1 It is also important to be aware that nits can be misidentified as dandruff, hair spray residue, or even dirt particles that have lodged into the patient’s scalp. -
Scabies, Incomplete Lupus Erythematosus and Henoch-Schonlein Purpura: a Case Report
Scabies, Incomplete Lupus Erythematosus and Henoch-Schonlein Purpura: A Case Report Yang Fang Wu First Aliated Hospital of Anhui Medical University Jing Jing Wang Jinling Hospital Hui Hui Liu First Aliated Hospital of Anhui Medical University Wei Xia Chen First Aliated Hospital of Anhui Medical University Peng Hu ( [email protected] ) First Aliated Hospital of Anhui Medical University https://orcid.org/0000-0002-2144-9806 Case report Keywords: Antinuclear antibody, Henoch-Schonlein purpura, immunoglobulin A, proteinuria, scabies Posted Date: September 18th, 2020 DOI: https://doi.org/10.21203/rs.3.rs-63971/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/8 Abstract BackgroundHenoch-Schonlein purpura (HSP) is a common autoimmune vasculitis in childhood. Although the detailed etiology of HSP remains unknown, several triggers, especially for infectious agents, have been proved to be associated with HSP onset. Case presentation: In the present report, we describe an unusual patient who suffered from HSP and incomplete lupus erythematosus (ILE) on day 8 after scabies, mainly based on nonthrombocytopenic purpura, abdominal pain, medium proteinuria, positive antinuclear antibody (ANA) and skin scrapings. A course of pulse methylprednisolone (10mg/kg/day) was administered for 6 days, followed by oral prednisone (1mg/kg/day). On day 18, the purpuric rashes almost disappeared, whereas medium proteinuria still existed. In this circumstance, a renal biopsy was performed with the informed consent of the parents. According to the criteria proposed by the International Study of Kidney Disease in Children, this patient was classied as class IIIb. The immunouorescence microscopy revealed granular deposits of IgA, IgM and C3 in the glomerular mesangium. -
Epidemiology, Diagnosis, and Treatment of Scabies in a Dermatology Office
J Am Board Fam Med: first published as 10.3122/jabfm.2017.01.160190 on 6 January 2017. Downloaded from ORIGINAL RESEARCH Epidemiology, Diagnosis, and Treatment of Scabies in a Dermatology Office Kathryn L. Anderson, MD, and Lindsay C. Strowd, MD Background: Scabies is a neglected skin disease, and little is known about current incidence and treat- ment patterns in the United States. The purpose of this study was to examine demographic data, treat- ment types, success of treatment, and misdiagnosis rate of scabies in an outpatient dermatology clinic. Methods: A retrospective chart review of patients diagnosed with scabies within the past 5 years was performed. Results: A total of 459 charts were identified, with 428 meeting inclusion criteria. Demographic data, diagnostic method, treatment choice, misdiagnosis rate, treatment failure, and itching after scabies are also reported. Children were the largest age group diagnosed with scabies, at 38%. Males (54%) were diagnosed with scabies more than females. The majority of diagnoses were made by visualizing ova, feces, or mites on light microscopy (58%). At the time of diagnosis, 45% of patients had been misdiag- nosed by another provider. Topical permethrin was the most common treatment used (69%), followed by a combination of topical permethrin and oral ivermectin (23%), oral ivermectin (7%), and other treatments (1%). Conclusion: Our findings suggest that more accurate and faster diagnostic methods are needed to limit unnecessary treatment and expedite appropriate therapy for scabies. (J Am