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Glaucoma Medical Therapy Ocular Tolerability, Adherence, and Patient Outcomes

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Glaucoma Medical Therapy Ocular Tolerability, Adherence, and Patient Outcomes CME Monograph November 30, 2017 September 23, 2016 Expiration: Original Release: November 1, 2016 Last Review: GLAUCOMA MEDICAL THERAPY OCULAR TOLERABILITY, ADHERENCE, AND PATIENT OUTCOMES ACTIVITY DESCRIPTION commercial interests in the form of Consultant/Advisory Therapy to lower intraocular pressure effectively reduces the Board: Alcon; Bausch & Lomb Incorporated; and Inotek risk of glaucoma progression. The rate of nonadherence with Pharmaceuticals Corporation; Contracted Research: Alcon; PROGRAM CHAIR therapy, however, remains high. Therapeutic nonadherence and F. Hoffmann-La Roche Ltd. is a complex and multifactorial issue that is influenced by Richard K. Parrish II, MD James C. Tsai, MD, MBA, had a financial agreement factors attributable to the physician, patient, and medication. or affiliation during the past year with the following Edward W. D. Norton Chair in Ophthalmology All medications have side effects, and tolerability issues can commercial interests in the form of Consultant/ Professor contribute to nonadherence if patients perceive that the Advisory Board: Aerie Pharmaceuticals, Inc; and Inotek disadvantages of therapy outweigh the benefits of controlling Director, Glaucoma Service Pharmaceuticals Corporation. a disease that is often asymptomatic. Therefore, the selection Bascom Palmer Eye Institute of initial and adjunctive therapy should consider the NEW YORK EYE AND EAR INFIRMARY OF MOUNT SINAI University of Miami Miller School of Medicine potential for tolerability issues that may adversely affect PEER REVIEW DISCLOSURE Miami, Florida adherence. Novel therapies in late-stage clinical development Joseph F. Panarelli, MD, had a financial agreement or affiliation will offer innovative mechanisms of action and unique risk/ during the past year with the following commercial interest FACULTY benefit profiles. The purpose of this educational activity in the form of Consultant/Advisory Board: Allergan is to update ophthalmologists on the prevalence of and EDITORIAL SUPPORT DISCLOSURES contributors to therapeutic nonadherence to glaucoma Robert D. Fechtner, MD Diane McArdle, PhD; Cynthia Tornallyay, RD, MBA, treatment, potential methods of addressing nonadherence, CHCP; Kimberly Corbin, CHCP; Barbara Aubel; and Professor and Chair and emerging medications with novel mechanisms of action Michelle Ong have no relevant commercial relationships to disclose. Department of Ophthalmology for managing glaucoma. State University of New York Upstate DISCLOSURE ATTESTATION TARGET AUDIENCE The contributing physicians listed above have attested to the Medical University This educational activity is intended for ophthalmologists. following: Syracuse, New York LEARNING OBJECTIVES 1) that the relationships/affiliations noted will not bias or otherwise influence their involvement in this activity; Upon completion of this activity, participants will be better 2) that practice recommendations given relevant to the Tony Realini, MD, MPH able to: companies with whom they have relationships/affiliations • Counsel patients on optimal administration and Associate Professor of Ophthalmology will be supported by the best available evidence or, absent adherence strategies evidence, will be consistent with generally accepted West Virginia University Eye Institute • Describe the effect of tolerability of glaucoma medical practice; and Morgantown, West Virginia medications on patient adherence 3) that all reasonable clinical alternatives will be discussed • Describe the mechanism of action of current and when making practice recommendations. James C. Tsai, MD, MBA emerging topical glaucoma therapies President OFF-LABEL DISCUSSION ACCREDITATION STATEMENT This CME activity includes discussion of unlabeled and/ New York Ear and Ear Infirmary of Mount Sinai This activity has been planned and implemented in or investigative uses of drugs. Please refer to the official System Chair, Department of Ophthalmology accordance with the accreditation requirements and policies prescribing information for each drug discussed in this of the Accreditation Council for Continuing Medical activity for FDA-approved dosing, indications, and warnings. Icahn School of Medicine at Mount Sinai Education (ACCME) through the joint providership of For Digital Editions Mount Sinai Health System New York Eye and Ear Infirmary of Mount Sinai and System Requirements: New York, New York MedEdicus LLC. The New York Eye and Ear Infirmary of Mount Sinai is accredited by the ACCME to provide If you are viewing this activity online, please ensure the continuing medical education for physicians. computer you are using meets the following requirements: CME REVIEWER FOR • Operating System: Windows or Macintosh In July 2013, the Accreditation Council for • Media Viewing Requirements: Flash Player or Adobe Reader NEW YORK EYE AND EAR INFIRMARY OF MOUNT SINAI Continuing Medical Education (ACCME) awarded New York Eye and Ear Infirmary of • Supported Browsers: Microsoft Internet Explorer, Joseph F. Panarelli, MD Mount Sinai “Accreditation with Commendation,” Firefox, Google Chrome, Safari, and Opera Assistant Professor of Ophthalmology for six years as a provider of continuing medical • A good Internet connection Icahn School of Medicine of Mount Sinai education for physicians, the highest accreditation New York Eye and Ear Infirmary of Mount Sinai status awarded by the ACCME. Privacy & Confidentiality Policies Associate Residency Program Director AMA CREDIT DESIGNATION STATEMENT http://www.nyee.edu/health-professionals/cme/enduring-activities New York Eye and Ear Infirmary at Mount Sinai The New York Eye and Ear Infirmary of Mount Sinai CME Provider Contact Information New York, New York designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim For questions about this activity, call 212-979-4383. only the credit commensurate with the extent of their TO OBTAIN AMA PRA CATEGORY 1 CREDIT™ participation in the activity. To obtain AMA PRA Category 1 Credit™ for this activity, read LEARNING METHOD AND MEDIUM GRANTOR STATEMENT the material in its entirety and consult referenced sources as This educational activity consists of a supplement and eight This continuing medical education activity is supported necessary. Complete the evaluation form along with the post (8) study questions. The participant should, in order, read through an unrestricted educational grant from Inotek test answer box within this supplement. Remove the Activity the learning objectives contained at the beginning of this Pharmaceuticals Corporation. Evaluation/Credit Request page from the printed supplement supplement, read the supplement, answer all questions in the or print the Activity Evaluation/Credit Request page from post test, and complete the Activity Evaluation/Credit Request DISCLOSURE POLICY STATEMENT the Digital Edition. Return via mail to Kim Corbin, Director, form. To receive credit for this activity, please follow the It is the policy of New York Eye and Ear Infirmary of ICME, New York Eye and Ear Infirmary of Mount Sinai, instructions provided on the post test and Activity Evaluation/ Mount Sinai that the faculty and anyone in a position to 485 Madison Avenue, 17th Floor, New York, NY 10022 or Credit Request form. This educational activity should take a control activity content disclose any real or apparent conflicts fax to (212) 353-5703. Your certificate will be mailed to maximum of 1.0 hour to complete. of interest relating to the topics of this educational activity, the address you provide on the Activity Evaluation/Credit and also disclose discussions of unlabeled/unapproved uses of Request form. Please allow 3 weeks for Activity Evaluation/ CONTENT SOURCE drugs or devices during their presentation(s). New York Eye Credit Request forms to be processed. There are no fees for This continuing medical education (CME) activity captures content and Ear Infirmary of Mount Sinai has established policies in participating in and receiving CME credit for this activity. from an expert roundtable discussion held on August 25, 2016. place that will identify and resolve all conflicts of interest prior to this educational activity. Full disclosure of faculty/planners Alternatively, we offer instant certificate processing and support Green CME. Please take this post test and evaluation This CME activity is copyrighted to MedEdicus LLC ©2016. and their commercial relationships, if any, follows. online by going to http://tinyurl.com/glaucomatherapy. All rights reserved. DISCLOSURES Upon passing, you will receive your certificate immediately. Robert D. Fechtner, MD, had a financial agreement You must score 70% or higher to receive credit for this This continuing medical education activity is jointly provided by or affiliation during the past year with the following activity, and may take the test up to 2 times. Upon registering New York Eye and Ear Infirmary of Mount Sinai and MedEdicus LLC. commercial interests in the form of Consultant/Advisory and successfully completing the post test, your certificate will Board: Alcon; ForSight VISION5; Glaukos Corporation; be made available online and you can print it or file it. Santen Pharmaceutical Co, Ltd; and Zeiss; Contracted Research: Aerie Pharmaceuticals, Inc. DISCLAIMER Richard K. Parrish II, MD, has no relevant commercial The views and opinions expressed in this educational activity relationships to disclose. are those of the faculty and do not necessarily represent the views of New York Eye and Ear Infirmary of Mount
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