bioRxiv preprint doi: https://doi.org/10.1101/015396; this version posted February 18, 2015. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Genetic evidence for an origin of the Armenians from Bronze Age mixing of multiple populations Marc Haber1, Massimo Mezzavilla1,2, Yali Xue1, David Comas3, Paolo Gasparini2, Pierre Zalloua4, Chris Tyler-Smith1,* 1The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambs. CB10 1SA, United Kingdom. 2Institute for Maternal and Child Health -IRCCS “Burlo Garofolo” - Trieste, University of Trieste, Italy. 3Institut de Biologia Evolutiva (CSIC–UPF), Departament de Ciències de la Salut i de la Vida, Universitat Pompeu Fabra, Barcelona, Spain 4The Lebanese American University, Chouran, Beirut, Lebanon *Corresponding author: Chris Tyler-Smith, The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, United Kingdom. Phone: +44(1223)-834244. Fax: +44(1223)-494919. E-mail:
[email protected] 1 bioRxiv preprint doi: https://doi.org/10.1101/015396; this version posted February 18, 2015. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Abstract The Armenians are a culturally isolated population who historically inhabited a region in the Near East bounded by the Mediterranean and Black seas and the Caucasus, but remain underrepresented in genetic studies and have a complex history including a major geographic displacement during World War One.