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Three-Year Follow up of the Phase 3 Pollux Study of Daratumumab Plus
This is a repository copy of Three-Year Follow up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Relapsed or Refractory Multiple Myeloma (RRMM). White Rose Research Online URL for this paper: http://eprints.whiterose.ac.uk/157106/ Version: Accepted Version Proceedings Paper: Bahlis, N, Dimopoulos, MA, White, DJ et al. (14 more authors) (2018) Three-Year Follow up of the Phase 3 Pollux Study of Daratumumab Plus Lenalidomide and Dexamethasone (D-Rd) Versus Lenalidomide and Dexamethasone (Rd) Alone in Relapsed or Refractory Multiple Myeloma (RRMM). In: Blood. ASH 2018 – 60th American Society of Hematology Annual Meeting and Exposition, 01-04 Dec 2018, San Diego, CA. American Society of Hematology . https://doi.org/10.1182/blood-2018-99-112697 © 2018 by The American Society of Hematology. This is an author produced version of a conference abstract published in Blood. Uploaded in accordance with the publisher's self-archiving policy. Reuse Items deposited in White Rose Research Online are protected by copyright, with all rights reserved unless indicated otherwise. They may be downloaded and/or printed for private study, or other acts as permitted by national copyright laws. The publisher or other rights holders may allow further reproduction and re-use of the full text version. This is indicated by the licence information on the White Rose Research Online record for the item. Takedown If you consider content in White Rose Research Online to be in breach of UK law, please notify us by emailing [email protected] including the URL of the record and the reason for the withdrawal request. -
Naming the Extrasolar Planets
Naming the extrasolar planets W. Lyra Max Planck Institute for Astronomy, K¨onigstuhl 17, 69177, Heidelberg, Germany [email protected] Abstract and OGLE-TR-182 b, which does not help educators convey the message that these planets are quite similar to Jupiter. Extrasolar planets are not named and are referred to only In stark contrast, the sentence“planet Apollo is a gas giant by their assigned scientific designation. The reason given like Jupiter” is heavily - yet invisibly - coated with Coper- by the IAU to not name the planets is that it is consid- nicanism. ered impractical as planets are expected to be common. I One reason given by the IAU for not considering naming advance some reasons as to why this logic is flawed, and sug- the extrasolar planets is that it is a task deemed impractical. gest names for the 403 extrasolar planet candidates known One source is quoted as having said “if planets are found to as of Oct 2009. The names follow a scheme of association occur very frequently in the Universe, a system of individual with the constellation that the host star pertains to, and names for planets might well rapidly be found equally im- therefore are mostly drawn from Roman-Greek mythology. practicable as it is for stars, as planet discoveries progress.” Other mythologies may also be used given that a suitable 1. This leads to a second argument. It is indeed impractical association is established. to name all stars. But some stars are named nonetheless. In fact, all other classes of astronomical bodies are named. -
Winter Observing Notes
Wynyard Planetarium & Observatory Winter Observing Notes Wynyard Planetarium & Observatory PUBLIC OBSERVING – Winter Tour of the Sky with the Naked Eye NGC 457 CASSIOPEIA eta Cas Look for Notice how the constellations 5 the ‘W’ swing around Polaris during shape the night Is Dubhe yellowish compared 2 Polaris to Merak? Dubhe 3 Merak URSA MINOR Kochab 1 Is Kochab orange Pherkad compared to Polaris? THE PLOUGH 4 Mizar Alcor Figure 1: Sketch of the northern sky in winter. North 1. On leaving the planetarium, turn around and look northwards over the roof of the building. To your right is a group of stars like the outline of a saucepan standing up on it’s handle. This is the Plough (also called the Big Dipper) and is part of the constellation Ursa Major, the Great Bear. The top two stars are called the Pointers. Check with binoculars. Not all stars are white. The colour shows that Dubhe is cooler than Merak in the same way that red-hot is cooler than white-hot. 2. Use the Pointers to guide you to the left, to the next bright star. This is Polaris, the Pole (or North) Star. Note that it is not the brightest star in the sky, a common misconception. Below and to the right are two prominent but fainter stars. These are Kochab and Pherkad, the Guardians of the Pole. Look carefully and you will notice that Kochab is slightly orange when compared to Polaris. Check with binoculars. © Rob Peeling, CaDAS, 2007 version 2.0 Wynyard Planetarium & Observatory PUBLIC OBSERVING – Winter Polaris, Kochab and Pherkad mark the constellation Ursa Minor, the Little Bear. -
Saevae Memorem Iunonis Ob Iram Juno, Veii, and Augustus
Acta Ant. Hung. 55, 2015, 167–178 DOI: 10.1556/068.2015.55.1–4.12 PATRICIA A. JOHNSTON SAEVAE MEMOREM IUNONIS OB IRAM JUNO, VEII, AND AUGUSTUS Arma virumque cano, Troiae qui primus ab oris Italiam, fato profugus, Laviniaque venit litora, multum ille et terris iactatus et alto vi superum saevae memorem Iunonis ob iram. Aen. I 1–4 Summary: A driving force in Vergil’s Aeneid is the hostility of Juno to the Trojans as they approach, and finally arrive in Italy. The epic in some ways mirrors the opposition encountered by Augustus as the new ruler of Rome. Juno’s opposition to the Trojans has its origin not only in Greek mythology, but in the his- tory of the local peoples of Italy with whom early Romans had to contend. From the outset of the poem she becomes the personification of these opposing forces. Once the Trojans finally reach mainland Italy, she sets in motion a long war, although the one depicted in the Aeneid was not as long as the real wars Ro- mans waged with the Latin League and with the many of the tribes of Italy, including the Veii. The reality of the wars Rome had to contend with are here compared to the relatively brief one depicted in the Aeneid, and the pacification of Juno reflects the merging of the different peoples of Rome with their subjugator. Key words: Juno, saeva, MARS acrostic, Etruscan Uni, evocatio, Veii, Fidenae, Aventinus, Gabii, Prae- neste, Tibur, Tanit, Saturnia, Apollo, Cumae and Hera, asylum, Athena, Aeneas, Anchises’ prophecy An important part of Augustan Myth is found in Vergil’s depiction of Juno, who is named in the opening lines of the epic and is a persistent presence throughout the poem. -
IAU Division C Working Group on Star Names 2019 Annual Report
IAU Division C Working Group on Star Names 2019 Annual Report Eric Mamajek (chair, USA) WG Members: Juan Antonio Belmote Avilés (Spain), Sze-leung Cheung (Thailand), Beatriz García (Argentina), Steven Gullberg (USA), Duane Hamacher (Australia), Susanne M. Hoffmann (Germany), Alejandro López (Argentina), Javier Mejuto (Honduras), Thierry Montmerle (France), Jay Pasachoff (USA), Ian Ridpath (UK), Clive Ruggles (UK), B.S. Shylaja (India), Robert van Gent (Netherlands), Hitoshi Yamaoka (Japan) WG Associates: Danielle Adams (USA), Yunli Shi (China), Doris Vickers (Austria) WGSN Website: https://www.iau.org/science/scientific_bodies/working_groups/280/ WGSN Email: [email protected] The Working Group on Star Names (WGSN) consists of an international group of astronomers with expertise in stellar astronomy, astronomical history, and cultural astronomy who research and catalog proper names for stars for use by the international astronomical community, and also to aid the recognition and preservation of intangible astronomical heritage. The Terms of Reference and membership for WG Star Names (WGSN) are provided at the IAU website: https://www.iau.org/science/scientific_bodies/working_groups/280/. WGSN was re-proposed to Division C and was approved in April 2019 as a functional WG whose scope extends beyond the normal 3-year cycle of IAU working groups. The WGSN was specifically called out on p. 22 of IAU Strategic Plan 2020-2030: “The IAU serves as the internationally recognised authority for assigning designations to celestial bodies and their surface features. To do so, the IAU has a number of Working Groups on various topics, most notably on the nomenclature of small bodies in the Solar System and planetary systems under Division F and on Star Names under Division C.” WGSN continues its long term activity of researching cultural astronomy literature for star names, and researching etymologies with the goal of adding this information to the WGSN’s online materials. -
Calendar of Roman Events
Introduction Steve Worboys and I began this calendar in 1980 or 1981 when we discovered that the exact dates of many events survive from Roman antiquity, the most famous being the ides of March murder of Caesar. Flipping through a few books on Roman history revealed a handful of dates, and we believed that to fill every day of the year would certainly be impossible. From 1981 until 1989 I kept the calendar, adding dates as I ran across them. In 1989 I typed the list into the computer and we began again to plunder books and journals for dates, this time recording sources. Since then I have worked and reworked the Calendar, revising old entries and adding many, many more. The Roman Calendar The calendar was reformed twice, once by Caesar in 46 BC and later by Augustus in 8 BC. Each of these reforms is described in A. K. Michels’ book The Calendar of the Roman Republic. In an ordinary pre-Julian year, the number of days in each month was as follows: 29 January 31 May 29 September 28 February 29 June 31 October 31 March 31 Quintilis (July) 29 November 29 April 29 Sextilis (August) 29 December. The Romans did not number the days of the months consecutively. They reckoned backwards from three fixed points: The kalends, the nones, and the ides. The kalends is the first day of the month. For months with 31 days the nones fall on the 7th and the ides the 15th. For other months the nones fall on the 5th and the ides on the 13th. -
A New Image of Elizabeth I: the Three Goddesses Theme in Art and Literature
A New Image of Elizabeth I: The Three Goddesses Theme in Art and Literature Helen Hackett abstract The National Portrait Gallery, London, recently acquired a previ- ously unknown portrait of Elizabeth I. This exquisite miniature of ca. 1590 shows the queen with Juno, Pallas, and Venus. Adapting the myth of the Judgment of Paris, it asserts that Elizabeth exceeds the three goddesses in majesty, wisdom, and beauty, and unites their qualities to create peace. In this essay, Helen Hackett elucidates this important new image through comparisons with analogues from literature and from Elizabethan portraiture. The enduring popularity of the Three Goddesses theme throughout Elizabeth’s reign is attributable to its adaptability to changing political circumstances. keywords: Queen Elizabeth I; Isaac Oliver; George Peele; Elizabethan royal portraiture; Elizabethan royal panegyric in may 2013 the National Portrait Gallery, London, announced that it had acquired a newly discovered portrait of Elizabeth I; the picture was subsequently dis- played in the exhibition Elizabeth I and Her People.1 This miniature, 115 by 157 mm, about the size of a modern postcard, was previously in private hands and unknown to art historians. It shows the queen encountering three goddesses—from left to right, Juno, Minerva (also known by her Greek name, Pallas), and Venus—in a reworking of the Judgment of Paris (fig. 1). Paris had to award a golden apple to the fairest of the god- desses; swayed by Venus’s offer of the most beautiful woman in the world, Helen of Troy, he chose Venus, sowing discord among the gods and initiating the Trojan war. -
Introduction the Constellations of the Winter
Introduction The winter sky is an excellent place to begin exploring the constellations that make up the night sky. Orion is the key, or signpost, for locating many of the other constellations in the winter sky. There are two convenient ways to locate all of the main constellations around Orion once Orion is located. Fortunately, Orion is easy to locate and well known to most people. The first way is to follow lines made by pairs of stars in Orion. The second way is to locate the great winter Orion is the key for hexagon of bright star around Orion. cracking the winter sky. The Constellations of the Winter Sky If you live in the northern latitudes and you scan the sky from the southern horizon to the region overhead, you should be able to see the following constellations on a clear winter night: Orion the Hunter, Canis Major the Great Dog, Canis Minor the Little Dog, Taurus the Bull, Auriga the Charioteer, Gemini the Twins and the Pleiades star cluster. (See the map on the next page). In Greek mythology, Orion was a great hunter who eventually offended the gods, especially Apollo. Apollo tricked Artemis, the Goddess of the hunt, into shooting Orion on a bet. When she discovered that she had shot Orion, she quickly lifted him to the heavens and made him immortal, where he now hunts eternally with his two dogs, Canis Major and Canis Minor. In front of him is his prey Taurus the Bull. The myths surrounding Auriga the Charioteer vary, but it is an ancient constellation dating back to at least to the Ancient Greeks. -
Estimation of the XUV Radiation Onto Close Planets and Their Evaporation⋆
A&A 532, A6 (2011) Astronomy DOI: 10.1051/0004-6361/201116594 & c ESO 2011 Astrophysics Estimation of the XUV radiation onto close planets and their evaporation J. Sanz-Forcada1, G. Micela2,I.Ribas3,A.M.T.Pollock4, C. Eiroa5, A. Velasco1,6,E.Solano1,6, and D. García-Álvarez7,8 1 Departamento de Astrofísica, Centro de Astrobiología (CSIC-INTA), ESAC Campus, PO Box 78, 28691 Villanueva de la Cañada, Madrid, Spain e-mail: [email protected] 2 INAF – Osservatorio Astronomico di Palermo G. S. Vaiana, Piazza del Parlamento, 1, 90134, Palermo, Italy 3 Institut de Ciènces de l’Espai (CSIC-IEEC), Campus UAB, Fac. de Ciències, Torre C5-parell-2a planta, 08193 Bellaterra, Spain 4 XMM-Newton SOC, European Space Agency, ESAC, Apartado 78, 28691 Villanueva de la Cañada, Madrid, Spain 5 Dpto. de Física Teórica, C-XI, Facultad de Ciencias, Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain 6 Spanish Virtual Observatory, Centro de Astrobiología (CSIC-INTA), ESAC Campus, Madrid, Spain 7 Instituto de Astrofísica de Canarias, 38205 La Laguna, Spain 8 Grantecan CALP, 38712 Breña Baja, La Palma, Spain Received 27 January 2011 / Accepted 1 May 2011 ABSTRACT Context. The current distribution of planet mass vs. incident stellar X-ray flux supports the idea that photoevaporation of the atmo- sphere may take place in close-in planets. Integrated effects have to be accounted for. A proper calculation of the mass loss rate through photoevaporation requires the estimation of the total irradiation from the whole XUV (X-rays and extreme ultraviolet, EUV) range. Aims. The purpose of this paper is to extend the analysis of the photoevaporation in planetary atmospheres from the accessible X-rays to the mostly unobserved EUV range by using the coronal models of stars to calculate the EUV contribution to the stellar spectra. -
Lunar Mansion Names in South-West China
Onoma 51 Journal of the International Council of Onomastic Sciences ISSN: 0078-463X; e-ISSN: 1783-1644 Journal homepage: https://onomajournal.org/ Lunar mansion names in South-West China: An etymological reconstruction of ancestral astronomical designations in Moso, Pumi, and Yi cultures compared with Chinese and Tibetan contexts DOI: 10.34158/ONOMA.51/2016/6 Xu Duoduo National University of Singapore (NUS), Asia Research Institute (ARI), Singapore [email protected] To cite this article: Xu Duoduo. 2016. Lunar mansion names in South-West China: An etymological reconstruction of ancestral astronomical designations in Moso, Pumi, and Yi cultures compared with Chinese and Tibetan contexts. Onoma 51, 113–143. DOI: 10.34158/ONOMA.51/2016/6 To link to this article: https://doi.org/10.34158/ONOMA.51/2016/6 © Onoma and the author. Lunar mansion names in South-West China: An etymological reconstruction of ancestral astronomical designations in Moso, Pumi, and Yi cultures compared with Chinese and Tibetan contexts Abstract: The present study aims at an etymological reconstruction of lunar mansion designations of the Moso, Pumi, and Yi people from South-West China. Those lunar mansions are generally named after animals. A systematic examination on these astronomical names reveals frequent borrowing processes among these cultures, extended to Tibetan and Chinese contexts. Three patterns of direct borrowing of the lunar mansion names can be highlighted in addition to compatible morphological structures in some designation. This comparative research also provides innovative 114 XU DUODUO solutions to several issues still unsolved from the current studies on lunar mansions focused on specific ethnic groups. -
Castor & Pollux
JEAN-PHILIPPE RAMEAU CASTOR & POLLUX (1754) Ainsworth | Sempey | De Negri | Margaine | Devieilhe | Immler PYGMALION RAPHAËL PICHON FRANZ LISZT JEAN-PHILIPPE RAMEAU (1683-1764) CD 2 Scène 4. Pollux, Hébé, une Suivante d’Hébé, Plaisirs célestes (Suite d’Hébé) CASTOR & POLLUX (version de 1754) 1 | Entrée d’Hébé et de sa suite 1’24 Tragédie en musique en 5 actes 2 | Chœur des Plaisirs célestes : Pouvez-vous nous méconnaître ? 0’45 Livret Pierre-Joseph Bernard (Gentil-Bernard) 3 | Pollux : Tout l’éclat de l’Olympe 0’24 4 | Petit chœur des Suivantes d’Hébé : Qu’Hébé, de fleurs toujours nouvelles 0’55 5 | Sarabande pour Hébé et sa Suite 1’12 CD 1 6 | Une Suivante d’Hébé : Voici des dieux 1’52 7 | Pollux : Ah ! Sans le trouble où je me vois 0’28 8 | Air pour Hébé. Une Suivante d’Hébé : Que nos jeux 3’23 1 | Ouverture 4’24 9 | Première et deuxième gavottes pour Hébé 1’36 PREMIER ACTE 10 | Récit Quand je romps vos aimables chaînes 0’51 2 | Scène 1. Cléone, Phébé. Cléone : L’hymen couronne votre sœur 4’16 3 | Scène 2. Télaïre : Éclatez mes justes regrets 2’40 QUATRIÈME ACTE 4 | Scène 3. Télaïre, Castor. Castor : Ah ! Je mourrai content 3’12 Scène 1. Phébé, [Esprits, Puissances magiques] 5 | Scène 4. Pollux, Télaïre, Castor. Pollux : Non, demeure, Castor 1’50 11 | Phébé & Chœurs : Esprits soutiens de mon pouvoir 2’40 12 | Descente de Mercure 0’14 Scène 5. Pollux, Télaïre, Castor, Spartiates. Pollux : Ces apprêts m’étaient destinés 13 | Mercure, Phébé, Pollux. Mercure : 1’25 6 | Chœur de Spartiates : Chantons l’éclatante victoire 1’44 Scène 2. -
Stars, Constellations, and Dsos [50 Pts]
Reach for the Stars B – KEY Bonus (+1) TRAPPIST-1 Part I: Stars, Constellations, and DSOs [50 pts] 1. Kepler’s SNR 2. Tycho’s SNR 3. M16 (Eagle Nebula) 4. Radiation pressure (wind) from young stars 5. Cas A 6. Extinction (from interstellar dust) 7. 30 Dor 8. [T10] Tarantula Nebula 9. LMC 10. Sgr A* 11. Gravitational interaction with orbiting stars (based on movement over time) 12. M42 (Orion Nebula) 13. [T8] Trapezium 14. (Charles) Messier 15. NGC 7293 (Helix Nebula) –OR– M57 (Ring Nebula) 16. TP-AGB (thermal pulse AGB) 17. Binary system –OR– stellar winds –OR– stellar rotation –OR– magnetic fields 18. Geminga 19. [T4] Jets from pulsar spin poles 20. X-ray 21. NGC 3603 22. Among the most massive & luminous stars known 23. T Tauri 24. FUors (FU Orionis stars) 25. NGC 602 26. Open cluster 27. LMC –AND– SMC 28. Irregular 29. Tidal forces –OR– gravity of MW 30. M1 (Crab Nebula) 31. PWN (pulsar wind nebula) 32. X-ray 33. M17 (Omega Nebula) 34. Omega Nebula –OR– Swan Nebula –OR– Checkmark Nebula –OR– Horseshoe Nebula 35. NGC 6618 36. Zeta Ophiuchi 37. Bow shock (from moving quickly through the ISM) 38. It “wobbles” across the sky (moves perpendicular to overall proper motion) 39. Procyon (α CMi) 40. Mizar –AND– Alcor 41. Mizar 42. Pollux (β Gem) 43. [T5] High rotational velocity 44. Altair (α Aql) –OR– Regulus (α Leo) –OR– Vega (α Lyr) 45. Polaris (α UMi) 46. Precession 47. Binary with observed Doppler shift of spectral lines 48. Beta Cephei variable (β Cep) 49.