6Th International Meeting April 5-6, 2011
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6th International Meeting Stem Cell Network North Rhine-Westphalia _April 5-6, 2011 _Final Program _Poster Abstracts _Company Profiles _Contact 3 _Program Tuesday, April 5th 8:00 - 9:00 am _Registration 9:00 - 9:30 am _Opening of the Meeting Svenja Schulze, Minister for Innovation, Science and Research of the State of North Rhine-Westphalia 9:30 - 11:00 am _Keynote Lectures, Chair: H. Schöler John Dick, Toronto: “Stem cells and cancer: are they relevant?” Ludwig Siep, Münster: “Ethical questions concerning research with induced pluripotent stem cells” 11:00 - 11:30 am _Coffee Break, Poster Session 11:30 - 12:30 pm _Session I: Disease Modeling, Chair: O. Brüstle Kevin Eggan, Cambridge Juan Carlos Izpisúa Belmonte, La Jolla 12:30 - 2:00 pm _Lunch Break, Poster Session 2:00 - 3:00 pm _Panel Discussion, Chair: L. Honnefelder “International regulation of research translation” 3:00 - 3:30 pm _Coffee Break, Poster Session 3:30 - 4:30 pm _Session II: Homing and Migration, Chair: P. Horn Francisco Sanchez-Madrid, Madrid Steffen Massberg, München 4:30 - 6:30 pm _Poster Session 7:00 - 10:30 pm _Networking event at the Zeche Zollverein (bus transport provided) 4 Wednesday, April 6th 8:00 – 9:00 am _Registration 9:00 - 10:00 am _Session III: Cell Fate Specification in Stem Cells of Model Organisms, Chair: C. Kaltschmidt Erika Matunis, Baltimore Elly Tanaka, Dresden 10:00 - 11:00 am _Session IV: Non-human Primate Pluripotent Stem Cells, Chair: S. Schlatt Erika Sasaki, Kawasaki Shoukrat Mitalipov, Portland 11:00 - 11:45 am _Coffee Break, Poster Session 11:45 am - 12:45 pm _Session V: Disease Modelling - Cancer Chair: T. Dittmar Andreas Trumpp, Heidelberg Eric Holland, New York 12:45 - 2:00 pm _Lunch Break, Poster Session 2:00 - 3:00 pm _Session VI: Transdifferentiation, Chair: M. Zenke Thomas Braun, Bad Nauheim Thomas Graf, Barcelona 3:00 - 3:30 pm _Coffee Break 3:30 - 4:30 pm _Session VII: Niche, Hypoxia and Metabolism, Chair: P. Wernet Norman Iscove, Toronto Michael Cross, Leipzig 4:30 - 5:30 pm _Session VIII: From Stem Cells to Tissues, Chair: A. Faissner Arnold Kriegstein, San Francisco Pierre Vanderhaeghen, Brussels 5:30 pm _Poster Awarding, Closing Remarks 5 _Register Bioengineering & Biomaterials Abstract 1 Carina Adamzyk Proliferation and differentiation of human mesenchymal stem cells on microstructured polystyrene surfaces .................................................................... 19 Abstract 2 Ferreira M.V Towards a 3D biomaterial-based expansion strategy for cord blood-de- rived CD34+ cells ......................................................................................................20 Abstract 3 Greulich, C, Uptake and intracellular fate of nanosilver within human mesenchymal stem cells ................................................................................................................... 21 Abstract 4 Tim Habijan Rapid manufacturing of porous nickel-titanium as a carrier for human mesenchymal stem cells ..........................................................................................23 Abstract 5 Mareike Hoss Germline-derived pluripotent stem cells for tissue engineering ...........................24 Abstract 6 George Kensah Murine induced pluripotent stem cells for cardiac tissue engineering .................25 Abstract 7 Michael Lenz Integrating quality control in the automated generation of induced pluripotent stem cells ...............................................................................................26 Abstract 8 Eva-Maria Materne Micro-scale human liver equivalents for chip based biomedical research ........... 27 Abstract 9 Fei Pan Effect of topography on the differentiation of human embryonic stem cells to neuronal lineage in the nano-micro range ..................................................28 Abstract 10 Roman Tsaryk The use of mesenchymal stem cells on collagen/ LMW HA gels for in- tervertebral disc regeneration ..................................................................................29 Abstract 11 Ilka Wagner Generation of human hair follicle equivalents in vitro for substance testing .......30 Chromatin & Epigenetics Abstract 12 Tahsin Stefan Barakat RNF12 activates XIST and is essential for X inactivation........................................32 6 Abstract 13 Manoj Kumar Gupta Beating clusters and cardiomyocytes derived from induced pluripotent stem (iPS) cells retain some genetic signature of somatic cells used for reprogramming ..........................................................................................................33 Abstract 14 Carmen M. Koch Specific age-associated DNA methylation changes in human dermal fibroblasts ..................................................................................................................34 Abstract 15 Tomasz Kolanowski Chromosome centromers positioning during differentiation of human myoblasts in in vitro culture .....................................................................................35 Abstract 16 Nadine Obier EED-dependent global and local chromatin states in pluripotent and dif- ferentiating mouse embryonic stem cells ...............................................................36 Abstract 17 Krishna Pantakani Germ cell specific gene Stra8 has an impact on the pluripotency network and functions as an epigenetic regulator ................................................................ 37 Abstract 18 Timour Prozorovski Sirt1 regulates neural stem cell homeostasis and plays a role in the re- sponse to cellular stress ...........................................................................................38 Abstract 19 Anne Schellenberg The landscape of cellular aging: long-term culture of mesenchymal stem cells is associated with specific changes in their DNA-methylation profile .........39 Abstract 20 Jianming Xu Positive cofactor 4 coordinates self-renewal and genome stability in mES cells 40 Development & Regeneration Abstract 21 Ruhel Ahmad Parthenogenetic human ES cells form functional neurons ...................................42 Abstract 22 Sebastian T. Balbach Reprogramming the embryonic cell cycle after somatic cell nuclear transfer ....43 Abstract 23 Alexandra A. Blak A novel and efficient system for the generation of neural progenitor cells from human pluripotent stem cells using STEMdiffTM neural products .............44 Abstract 24 Verena Chankiewitz The development of the limbal region in chicken embryos ...................................45 Abstract 25 Sandra Danner A novel xenogenic co-culture system to examine neuronal differentiation capability of various adult human stem cells ..........................................................46 7 Abstract 26 Xiaolei Ding Polycomb group protein Bmi1 promotes hematopoietic cell development from ES cells ..............................................................................................................47 Abstract 27 Wiebke Garrels Transmission of Venus fluorophore protein to embryonic development by transgenic and non-transgenic boar spermatozoa ................................................48 Abstract 28 Boris Greber FGF2/ERK signaling inhibits neural induction in human embryonic stem cells ..49 Abstract 29 Takashi Hiiragi A novel fluorescence gene-trap identifies molecular dynamics during early mouse development ........................................................................................50 Abstract 30 Jörg Jende Investigating conditions for the induction of cultivatable neural progeni- tor populations from induced pluripotent stem cells ............................................. 51 Abstract 31 Michael Karus Regulation of astrocyte generation by the extracellular matrix molecule Tenascin C ..................................................................................................................52 Abstract 32 Atsuko Kasahara Mitochondrial morphology affects cardiomyocyte differentiation of mouse embryonic stem cells through Calcineurin and Notch signaling pathways ....................................................................................................................53 Abstract 33 Katherina Katsirntaki Differentiation of murine embryonic (mESCs) and induced pluripotent stem cells (miPSCs) into definitive endoderm and airway epithelial cells ...........54 Abstract 34 Julee Kim Endothelial-like cells derived from adult murine germline-derived pluripo- tent stem cells ...........................................................................................................55 Abstract 35 Zsuzsa Kovacs TOX3 is a neuronal transcription factor expressed in neuronal precursor cells ..56 Abstract 36 Julia Ladewig Paracrine signals restrict neuronal migration from human neural precur- sor cell containing grafts .......................................................................................... 57 Abstract 37 Eva Lorsy Putative tissue resident stem cells in the testes of adult Axolotl (Am- bystoma mexicanum) ...............................................................................................58 Abstract 38 Komal Loya Alternative pluripotent stem cells as a source of hepatic cells .............................59 8 Abstract 39 Raphaela Lünskens Efficient generation of oligodendrocytes from human ESC- und iPSC- derived gliogenic neural stem cells ......................................................................... 60 Abstract 40 Katrin Montzka Mesenchymal stromal cells immobilized in an oriented 3D scaffold ac- celerate functional recovery after