Saturday, July 13th, 2013 Session 6 Stem Cells and Cancer Contact Chairpersons: Petra BOUKAMP, S F B 8 7 3 Session 5 Haematopoesis Ana MARCINIAK-CZOCHRA Christiane Wickenhoefer Chairpersons: Claudia SCHOLL, SFB 873 office / Project Coordination Andreas TRUMPP 11:00 - 11:25 Dominique BONNET Department of V London Research Institute, London - UK Im Neuenheimer Feld 410 | D-69120 Heidelberg Stem Cells in Development 08:30 - 08:45 Hans-Reimer RODEWALD New Insights into Human Hematopoietic Phone: +49 6221 56-5493 | Fax: 49 6221 56-5054 and Disease DKFZ, Heidelberg – Germany Stem Cells and Their Niche E-mail: [email protected] th th Activity and Lineage Output in 12 and 13 of July 2013 Unperturbed Hematopoiesis 11:25 - 11:40 Anthony D. HO Conference Location: German Cancer Research Center | Center of Communications Department of Medicine, German Cancer Research Center (DKFZ) Im Neuenheimer Feld 280 | D-69120 Heidelberg 08:45 - 09:10 Tariq ENVER Heidelberg – Germany Center of Communications University College, London – UK Heterogeneity of Human Leukemia Stem Im Neuenheimer Feld 280 | D-69120 Heidelberg

Wohnheime 536 Transcriptional Control of Normal and Cells - Does It Matter? P 502 522 670 P 535 561 560 501 521 Pädagogische 500 Leukemic Haematopoiesis 672 Hochschule H Im Neuenheimer Feld H 676 - 683 Admin P 236 H 294 293/ 253/ 11:40 - 11:55 Jochen UTIKAL 292 254 H H 235 H Hörsäle 234 09:10 - 09:25 Hellmut AUGUSTIN Clinic for Dermatology, Venereology and P Chemie

252 7050 269 330 400 350 OMZ 231 232 P DKFZ, Heidelberg – Germany Allergiology, Mannheim - Germany 270 - 278 HIT Hörsaal 230 Kopfklinik 368 308 H 348 Regulation of Induced Pluripotent Cancer Cells Tiergartenstraße 328

229 367 Quiescence and Mobilization through the 347 327 307 288 H 366 Theoretikum 306 Angiopoietin / Tie System 11:55 - 12:10 Andreas TRUMPP P 410 Physik P P Medizinische 305 365 345 227 Klinik 325 Blutbank P 344b P DKFZ, Heidelberg – Germany 364 324 H 344a Mensa 242 304 P

09:25 - 09:50 Karl WELTE Leukemic and Metastasis Stem Cells landeplatz 282 Hubschrauber-

340 Berliner Straße Berliner Botanischer Garten H 360 222 Medical School, Hannover - Germany ZOO 281 261 241 223 P P DKFZ 154 P 280 H 221 220 Leukemogenesis in Congenital Bone 12:10 – 13:10 Key Note Lecture 160 162 370 DKFZ 260 161 240 151 320 P 155 153 P Marrow Failure Syndromes Introduction: Anthony D. HO Kinderklinik H 156 P Chirurgie 117 Kirschnerstraße LIZ P Liegend- 110 100 H eingang Jahn-Straße105 159 111 114 115 Jahn-Straße 131 H

133/ 130 Jahnstraße H Nierenzentrum 134 09:50 - 10:15 Martin ZENKE Bart BARLOGIE 119 119 P 132 112 Max-Plank- Institute for Biomedical Technologies, University of Arkansas for Medical Institut

Aachen - Germany Sciences, Little Rock / Arkansas – USA Neckar From Hematopoietic Stem Cells towards My Journey with Myeloma – from No Cure Antigenpresenting Dendritic Cells to Cure with Stem Cells Sponsors Collaborative Research Center / SFB 873 10:15 - 11:00 Coffee Break 13:10 - 13:30 Awarding Ceremony www.sfb873.de Faculty Medal of the Faculty of Medicine Heidelberg Claus R. BARTRAM, Dean of the Medical Roche € 10.000 Celgene € 6.000 Novartis € 6.000 Faculty,

13:30 Lunch ID24339 Unternehmenskommunikation/Medienzentrum Universitätsklinikum Heidelberg Universitätsklinikum Unternehmenskommunikation/Medienzentrum ID24339 Amgen € 5.000 Chugai € 1.300 Octapharma € 500 UniversitätsKlinikum Heidelberg

Friday, July 12th, 2013 Session 2 Signaling Session 3 Differentiation Session 4 Stem Cell Niche Chairpersons: Ingrid LOHMANN, Chairpersons: Ana MARTIN-VILLALBA, Chairpersons: Marieke ESSERS, 08:15 Opening Thomas HOLSTEIN Bruce EDGAR Hellmut AUGUSTIN Anthony D. HO Spokesperson SFB 873 11:15 - 11:30 Christof NIEHRS 13:30 - 13:55 Oliver BRÜSTLE 15:30 - 15:55 Xi LI DKFZ, Heidelberg - Germany Institute for Reconstructive Neurobiology, Stowers Institute for Medical Research, 08:20 - 08:30 Greetings Mitotic Wnt Signalling Bonn – Germany Kansas City - USA Thomas RAUSCH Differentiating Human Pluripotent Stem Targeting Quiescent and Active Cancer Vice-rector, Heidelberg University - Germany 11:30 - 11:55 Mariann BIENZ Cells for Neurological Disease Modeling Stem Cells in Adenoma MRC Laboratory of Molecular Biology, Otmar D. WIESTLER Cambridge - UK 13:55 - 14:20 Magdalena GÖTZ 15:55 - 16:10 Michael BOUTROS Chairman of the Management Board and Wnt Signalosomes and Degradasomes Helmholtz Center, Munich - Germany Cell and Molecular Biology, Scientific Director, German Cancer Research Novel Factors Regulating Neural Stem Cell Mannheim – Germany Center (DKFZ), Heidelberg - Germany 11:55 - 12:10 Thomas HOLSTEIN Differentiation and Brain Size Mechanisms of Wnt Secretion Centre for Organismal Studies (COS), Session 1 Pluripotency Heidelberg – Germany 14:20 - 14:45 Lukas SOMMER 16:10 - 16:35 Paul FRENETTE Chairpersons: Jan LOHMANN, Wnt Signaling and the Evolution of Anatomical Institute, Zurich - Switzerland Albert Einstein College of Medicine, Michael BOUTROS Stem Cells Neural Crest Stem Cells in Development New York - USA and Tumor Formation Microenvironmental Control of Stem 08:30 - 09:30 Key Note Lecture 12:10 - 12:25 Herbert STEINBEISSER Cell Behaviour Introduction: Jan LOHMANN Institute of Human Genetics, 14:45 - 15:00 Jochen WITTBRODT Medical Faculty, Heidelberg – Germany COS, Heidelberg – Germany 16:35 - 16:50 Jan LOHMANN Rudolf JAENISCH IGF/Wnt Interactions in Cell Differentiation Retinal Stem Cells in Growth and COS, Heidelberg - Germany MIT, Cambridge, Massachusetts – USA Regeneration A Novel Regulator of Plant Stem Cell Stem Cells, Reprogramming, Therapy: 12:25 - 13:30 Lunch Proliferation Promise, Problems, Reality 15:00 - 15:30 Coffee Break 16:50 - 17:15 Thomas BOSCH 09:30 - 09:45 Takashi HIIRAGI Zoological Institute, Kiel - Germany EMBL, Heidelberg - Germany Stem Cell Decision Making in Hydra Symmetry Breaking in the Mouse 17:15 - 17:30 Petra BOUKAMP 09:45 - 10:10 Linheng LI DKFZ, Heidelberg - Germany Stowers Institute for Medical Research, The Niche Guarantees Human Epidermal Kansas City – USA Stem Cell Maintenance and Function Niche, Signaling and Epigenetic Regulation of Stem Cells 17:30 Social event Open end 10:10 - 10:35 Niels GEIJSEN Hubrecht Institute, Utrecht - The Netherlands Dazl‘in Germ Cells and Embryonic Stem Cells

10:35 - 11:15 Coffee Break