Alimentary Tract and Metabolism Drugs Created by the Njardarson Group (The University of Arizona): Edon Vitaku, Elizabeth A. Ilardi, Monica A. Fallon, Erik B. Gerlach, Jack Siqueiros, Jón T. Njarðarson
Magnesium Sulfate Magnesium Sulfate Calcium Chloride Papaverine Potassium Chloride Guanadine Streptomycin Azulfidine Banthine Sus-phrine Sulfite Fungizone Cortef Acetate Achromycin Pamine Pro-Banthine Cortef Acetate Meticorten Medicortelone Aristocort Decadron ( Magnesium Sulfate ) ( Magnesium Sulfate ) ( Calcium Chloride ) ( Papaverine ) ( Potassium Chloride ) ( Guanidine ) ( Streptomycin ) ( Sulfasalazine ) ( Methantheline ) ( Epinephrine ) ( Amphotericin B ) ( Hydrocortisone ) ( Tetracycline ) ( Methylscopolamine ) ( Propantheline ) ( Hydrocortisone ) ( Prednisone ) ( Prednisolone ) ( Triamcinolone ) ( Dexamethasone )
LAXATIVE MINERAL SUPPLEMENT MINERAL SUPPLEMENT GASTROINTESTINAL DISORDERS MINERAL SUPPLEMENT ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. GASTROINTESTINAL DISORDERS STOMATOLOGICAL PREP ANTIDIAR., ANTIINFLA. & ANTIINF. STOMATOLOGICAL PREP STOMATOLOGICAL PREP GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. STOMATOLOGICAL PREP STOMATOLOGICAL PREP Approved 1900s Approved 1900s Approved 1900s Approved 1915 Approved 1920s Approved 1939 Approved 1946 Approved 1950 Approved 1950s Approved 1951 Approved 1951 Approved 1953 Approved 1953 Approved 1953 Approved 1953 Approved 1953 Approved 1955 Approved 1955 Approved 1957 Approved 1958
Diabinese Tenuate Ionamin Durabolin Diphenoxylate Lomotil Antrenyl Polymyxin B Phenformin Celestone Orinase Flagyl Neo-Fradin Osmitrol Vancocin Mycostatin Neo-Fradin Dymelor Anavar 8-Hour Bayer ( Chlorpropamide ) ( Diethylpropion ) ( Phentermine ) ( Nandrolone ) ( Diphenoxylate ) ( Atropine & Diphenoxylate ) ( Oxyphenonium ) ( Polymyxin B ) ( Phenformin ) ( Betamethasone ) ( Tolbutamide ) ( Metronidazole ) ( Neomycin ) ( Mannitol ) ( Vancomycin ) ( Nystatin ) ( Neomycin ) ( Acetohexamide ) ( Oxandrolone ) ( Aspirin )
ANTIDIABETIC AGENT ANTI-OBESITY AGENT ANTI-OBESITY AGENT ANABOLIC AGENT ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIABETIC AGENT ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIABETIC AGENT STOMATOLOGICAL PREP STOMATOLOGICAL PREP LAXATIVE ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIABETIC AGENT ANABOLIC AGENT STOMATOLOGICAL PREP Approved 1958 Approved 1959 Approved 1959 Approved 1959 Approved 1960 Approved 1960 Approved 1960s Approved 1960s Approved 1960s Approved 1961 Approved 1961 Approved 1963 Approved 1964 Approved 1964 Approved 1964 Approved 1964 Approved 1964 Approved 1964 Approved 1964 Approved 1965
Fungizone Tolinase Vibramycin Daricon Anaspaz Pathilon Prantal Gliclazide Minocin Atropen Kantrax Sanorex Lotrimin Hibiclens Vanceril Imodium Cephulac Tagamet Ranitidine Natacyn ( Amphotericin B ) ( Tolazamide ) ( Doxycycline ) ( Oxyphencyclimine ) ( Hyoscyamine ) ( Tridihexethyl ) ( Diphemanil ) ( Gliclazide ) ( Minocycline ) ( Atropine ) ( Kanamycin ) ( Mazindol ) ( Clotrimazole ) ( Chlorhexidine ) ( Beclomethasone ) ( Loperamide ) ( Lactulose ) ( Cimetidine ) ( Ranitidine ) ( Natamycin )
STOMATOLOGICAL PREP ANTIDIABETIC AGENT STOMATOLOGICAL PREP GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS ANTIDIABETIC AGENT STOMATOLOGICAL PREP GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. ANTI-OBESITY AGENT STOMATOLOGICAL PREP STOMATOLOGICAL PREP ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. LAXATIVE ACID RELATED DISORDERS ACID RELATED DISORDERS STOMATOLOGICAL PREP Approved 1966 Approved 1966 Approved 1967 Approved 1970s Approved 1970s Approved 1970s Approved 1970s Approved 1970s (AUS/IND/PHL) Approved 1971 Approved 1973 Approved 1973 Approved 1973 Approved 1975 Approved 1976 Approved 1976 Approved 1976 Approved 1976 Approved 1977 Approved 1977 Approved 1978
Natacyn Reglan Transderm Pirenzepine Domperidone Magnacort Carafate Glucotrol Cesamet Marinol Pepcid L-Carnitine Ammonul Axid Cytotec Prilosec PhosLo Fenfluramine Redux Zofran ( Natamycin ) ( Metoclopramide ) ( Scopolamine ) ( Pirenzepine ) ( Domperidone ) ( Hydrocortamate ) ( Sucralfate ) ( Glipizide ) ( Nabilone ) ( Marinol ) ( Famotidine ) ( L-Carnitine ) ( Benzoic & Phenylacetic Acids ) ( Nizatidine ) ( Misoprostol ) ( Omeprazole ) ( Calcium Acetate ) ( Fenfluramine ) ( Dexfenfluramine ) ( Ondansetron )
ANTIDIAR., ANTIINFLA. & ANTIINF. GASTROINTESTINAL DISORDERS ANTIEMETIC & ANTINAUSEANT ACID RELATED DISORDERS GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. ACID RELATED DISORDERS ANTIDIABETIC AGENT ANTIEMETIC & ANTINAUSEANT ANTIEMETIC & ANTINAUSEANT ACID RELATED DISORDERS OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD ACID RELATED DISORDERS ACID RELATED DISORDERS ACID RELATED DISORDERS MINERAL SUPPLEMENT ANTI-OBESITY AGENT ANTI-OBESITY AGENT ANTIEMETIC & ANTINAUSEANT Approved 1978 Approved 1979 Approved 1979 Approved 1980s (EUR/JPN) Approved 1980s (EUR/CAN) Approved 1980s Approved 1981 Approved 1984 Approved 1985 Approved 1985 Approved 1986 Approved 1986 Approved 1987 Approved 1988 Approved 1988 Approved 1989 Approved 1990 Approved 1990s Approved 1990s Approved 1991
Orfadin Propulsid Kytril Cystagon Prevacid Amaryl Precose Glucophage Aphthasol Glyset Anzemet Pulmicort Meridia Prelay Prandin Prevpac Arthrotec Zemplar Isopto Homatropine AcipHex ( Nitisinone ) ( Cisapride ) ( Granisetron ) ( Cysteamine ) ( Lansoprazole ) ( Glimepiride ) ( Acarbose ) ( Metformin ) ( Amlexanox ) ( Miglitol ) ( Dolasetron ) ( Budesonide ) ( Sibutramine ) ( Troglitazone ) ( Repaglinide ) ( Amoxicillin, Clarithromycin & Lansoprazole ) ( Diclofenac & Misoprostol ) ( Paricalcitol ) ( Homatropine ) ( Rabeprazole )
OTHER ALIM. TRACT & MET. PROD GASTROINTESTINAL DISORDERS ANTIEMETIC & ANTINAUSEANT OTHER ALIM. TRACT & MET. PROD ACID RELATED DISORDERS ANTIDIABETIC AGENT ANTIDIABETIC AGENT ANTIDIABETIC AGENT STOMATOLOGICAL PREP ANTIDIABETIC AGENT ANTIEMETIC & ANTINAUSEANT ANTIDIAR., ANTIINFLA. & ANTIINF. ANTI-OBESITY AGENT ANTIDIABETIC AGENT ANTIDIABETIC AGENT ACID RELATED DISORDERS ACID RELATED DISORDERS VITAMIN ACID RELATED DISORDERS ACID RELATED DISORDERS Approved 1991 Approved 1993 Approved 1993 Approved 1994 Approved 1995 Approved 1995 Approved 1995 Approved 1995 Approved 1996 Approved 1996 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1997 Approved 1998 Approved 1999 Approved 1999
Xenical Avandia Actos Protonix Lotronex Colazal Starlix Glucovance NexIUM Canasa Rebetol Zelnorm Alinia Eloxatin Gleevec Hepsera Pegasys SecreFlo Pediarix Avandamet ( Orlistat ) ( Rosiglitazone ) ( Pioglitazone ) ( Pantoprazole ) ( Alosetron ) ( Balsalazide ) ( Nateglinide ) ( Glyburide & Metformin ) ( Esomeprazole ) ( Mesalamine ) ( Ribavirin ) ( Tegaserod ) ( Nitazoxanide ) ( Oxaliplatin, 5-Fluorouracil, & Leucovorin ) ( Imatinib ) ( Adefovir Dipivoxil ) ( Peginterferon Alfa-2a ) ( Secretin ) ( Pediarix ) ( Metformin & Rosiglitazone )
ANTI-OBESITY AGENT ANTIDIABETIC AGENT ANTIDIABETIC AGENT ACID RELATED DISORDERS GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIABETIC AGENT ANTIDIABETIC AGENT ACID RELATED DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD ANTIDIAR., ANTIINFLA. & ANTIINF. OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD ANTIDIABETIC AGENT Approved 1999 Approved 1999 Approved 1999 Approved 2000 Approved 2000 Approved 2000 Approved 2000 Approved 2000 Approved 2001 Approved 2001 Approved 2001 Approved 2002 Approved 2002 Approved 2002 Approved 2002 Approved 2002 Approved 2002 Approved 2002 Approved 2002 Approved 2002
Metaglip Emend Zavesca Aloxi Oxytrol Prevacid Naprapac Xifaxan Avastin Erbitux Zegerid Tygacil Baraclude Nexavar Actoplus MET Avandaryl Amitiza Tyzeka Duetact Torisel Janumet ( Glipizide & Metformin ) ( Aprepitant ) ( Miglustat ) ( Palonosetron ) ( Oxybutynin ) ( Lansoprazole & Naproxen ) ( Rifaximin ) ( Bevacizumab ) ( Cetuximab ) ( Omeprazole & Sodium Bicarbonate ) ( Tigecycline ) ( Entecavir ) ( Sorafenib ) ( Metformin & Pioglitazone ) ( Glimepiride & Rosiglitazone ) ( Lubiprostone ) ( Telbivudine ) ( Glimepiride & Pioglitazone ) ( Temsirolimus ) ( Metformin & Sitagliptin )
ANTIDIABETIC AGENT ANTIEMETIC & ANTINAUSEANT OTHER ALIM. TRACT & MET. PROD ANTIEMETIC & ANTINAUSEANT OTHER ALIM. TRACT & MET. PROD ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD ANTIDIABETIC AGENT ANTIDIABETIC AGENT GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS ANTIDIABETIC AGENT GASTROINTESTINAL DISORDERS ANTIDIABETIC AGENT Approved 2002 Approved 2003 Approved 2003 Approved 2003 Approved 2003 Approved 2003 Approved 2004 Approved 2004 Approved 2004 Approved 2004 Approved 2005 Approved 2005 Approved 2005 Approved 2005 Approved 2005 Approved 2006 Approved 2006 Approved 2006 Approved 2007 Approved 2007
Rotari Cimzia Enterig Tysabri Viread Prandimet Zenpep Afinitor Votrient Oravig Oravig Herceptin Pancreaze Vimovo Cayston Divicid Duexis Incivek Rective Sutent ( Rotavirus Vaccine ) ( Certolizumab Pegol ) ( Alvimopan ) ( Natalizumab ) ( Tenofovir ) ( Metformin & Repaglinide ) ( Pancrelipase ) ( Everolimus ) ( Pazopanib ) ( Miconazole ) ( Miconazole ) ( Trastuzumab ) ( Pancrelipase ) ( Naproxen & Esomeprazole ) ( Aztreonam ) ( Fidamoxicin ) ( Ibuprofen & Famotidine ) ( Telaprevir ) ( Nitroglycerin ) ( Sunitinib Maleate )
ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIAR., ANTIINFLA. & ANTIINF. ANTIDIABETIC AGENT OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD STOMATOLOGICAL PREP ANTIDIAR., ANTIINFLA. & ANTIINF. OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD GASTROINTESTINAL DISORDERS OTHER ALIM. TRACT & MET. PROD ANTIDIAR., ANTIINFLA. & ANTIINF. OTHER ALIM. TRACT & MET. PROD GASTROINTESTINAL DISORDERS OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD Approved 2008 Approved 2008 Approved 2008 Approved 2008 Approved 2008 Approved 2008 Approved 2009 Approved 2009 Approved 2009 Approved 2010 Approved 2010 Approved 2010 Approved 2010 Approved 2010 Approved 2010 Approved 2011 Approved 2011 Approved 2011 Approved 2011 Approved 2011
Victrelis Elelyso Fulyzaq Gattex Linzess Stivarga Xtandi Zaltrap Inlyta Kalydeco ( Boceprevir ) ( Taliglucerase alfa ) ( Crofelemer ) ( Teduglutide ) ( Linaclotide ) ( Regorafenib ) ( Enzalutamide ) ( Ziv-Aflibercept ) ( Axitinib ) ( Ivacaftor )
GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS ANTIDIAR., ANTIINFLA. & ANTIINF. GASTROINTESTINAL DISORDERS GASTROINTESTINAL DISORDERS OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD OTHER ALIM. TRACT & MET. PROD Approved 2011 Approved 2012 Approved 2012 Approved 2012 Approved 2012 Approved 2012 Approved 2012 Approved 2012 Approved 2012 Approved 2012
All drugs are considered FDA approved in the U.S. following the passage of the Pure Food and Drugs Act in 1906. http://www.fda.gov/Drugs/InformationOnDrugs/ApprovedDrugs/ * Initially approved outsides of the U.S.