springer.com/librarybooks Springer News 10/2006 Chemistry 79

Advances in Biochemical M. N. Berberan-Santos, Institute Superior Técnico, K. W. Böddeker, Technische Universität Hamburg- Engineering / Biotechnology Lisboa, Portugal (Ed .) Harburg, Germany Volume 106 Fluorescence of Liquid Separations with

A. Kumar, I. Y. Galaev, B. Mattiasson, Supermolecules, Polymers, Membranes Lund University, Sweden (Eds .) and Nanosystems An Introduction to Barrier Interference Cell Separation The field of fluorescence continues to steadily Exploiting barrier interference is the challenge of Fundamentals, Analytical and Preparative grow, both in its fundamental aspects and in membrane separation science and technology. This Methods applications in highly interdisciplinary areas book is about the principles behind. As membrane including analytical, physical and organic chem- processes, barrier separations independently have istry, molecular sciences, biology, biomedicine acquired their peculiar identities and colourful Features and medical research. The 4th volume in the diversity, each fondling its own tradition, each 7 Covers trends in modern biotechnology 7 All Springer Series on Fluorescence focuses on the adhering to its own terminology (down to defying aspects of this interdisciplinary technology, where fluorescence of anosystems, polymers and super- SI units), each earning different public attention knowledge, methods and expertise are required molecules, and the development and application and support. The plan of this book is to present the from chemistry, biochemistry, microbiology, of fluorescent probes. Special emphasis is placed relevant thermodynamic features of fluid mixtures genetics, chemical engineering and computer on the fluorescence of artificial and biological in contact with semipermeable barriers, then to science, are treated 7 More information as well as nanosystems, single molecule fluorescence and the apply this information in deriving the working the electronic version available at springer.com luminescence of polymers, micro- and nanopar- principles and design requirements of individual ticles and nanotubes. Fluorescence microscopy and membrane separation processes. The membranes, Contents fluorescence correlation spectroscopy are covered by this approach, are introduced by way of the M. B. Dainiak, A. Kumar, I.Yu. Galaev, B. Matti- as well. Historical aspects of this growing field and mass transport and selectivity demands which they asson: Methods in Cell Separations.- S.F. Ibrahim, an overview of fluorescence applications are also are to meet. This book gives a survey, in systematic G. van den Engh: Flow Cytometry and Cell provided. order, of the terms and concepts by which barrier Sorting.- A.A. Neurauter, M. Bonyhadi, E. Lien, separations operate, and through which practical L. Nokleby, E. Ruud, S. Camacho, T. Aarvak: Cell Features membrane separation processes are designed. Isolation and Expansion Using Dynabeads.- 7 Focusses on the fluorescence of nanosystems, J. Hubble: Affinity Adsorption of Cells to Surfaces polymers and supermolecules and the develop- Features and Strategies for Cell Detachment.- M.B. Dainiak, ment and application of fluorescent probes 7 Exploiting barrier interference is the challenge I.Yu. Galaev, A. Kumar, F.M. Plieva, B. Mattiasson: 7 Special emphasis is placed on the fluorescence of membrane separation science and technology Chromatography of Living Cells Using Super- of artificial and biological nanosystems, single 7 This book is about the principles behind macroporous Hydrogels, Cryogels.- R.E. Nordon: molecule fluorescence, luminescence of polymers, 7 Provides expert knowledge as an survey, in Hollow-Fibre Affinity Cell Separation.- J.M.S. of micro- and nanoparticles, and of nanotubes systematic order, of the terms and concepts by Cabral: Cell Partitioning in Aqueous Two-Phase 7 Fluorescence microscopy and fluorescence which barrier separations operate, and through Polymer Systems.- M. Kamihira, A. Kumar: Devel- correlation spectroscopy are also covered which practical membrane separation processes opment of Separation Technique for Stem Cells. are designed Fields of interest Fields of interest Physical Chemistry; Analytical Chemistry; Nano- Contents Biotechnology; Cell Biology; Analytical Chemistry technology Preface.- Symbols and abbreviations.-An introduc- tion to barrier separation.- The thermodynamic Target groups Target groups connection.- Osmosis et cetera.- Membrane filtra- Libraries and scientists in biomedicine, biotech- Practitioners and researchers in organic and tion.- Pervaporation versus evaporation.- What nology, biochemical/chemical engineering and physical chemistry and in material sciences, membranes are about.- Tracing membrane science, applied microbiology, university institutes, analytical chemists, molecular biologists, biophysi- an historical account.- Appendices. research groups in industry cists, biologists Fields of interest Discount group Discount group Industrial Chemistry/Chemical Engineering; P P Physical Chemistry; Biotechnology

Target groups Graduate students

Discount group P

Due December 2007 Due December 2007 Due November 2007 2008 . Approx . 470 p . 150 illus . (Springer Series on 2008 . XII, 180 p . 78 illus ., 3 in color . Hardcover Fluorescence, Volume 4) Hardcover 2008 . Approx . 130 p . 41 illus . Hardcover 7 approx. $199.00 7 approx. $249.00 7 $69.95 ISBN 978-3-540-75262-2 ISBN 978-3-540-73927-2 ISBN 978-3-540-47451-7 80 Chemistry Springer News 10/2007 springer.com/booksellers

G. Govil, K. Chary, Tata Institute of Fundamental A. C. Hoffmann, University of Bergen, Norway; N. Kockmann, University of Freiburg, Germany Research, Mumbai, India L. E. Stein, Process Engineering Consultant, Houston, TX, USA Transport Phenomena in NMR in Biological Systems Micro Process Engineering From Molecules to Human Gas Cyclones and Swirl Tubes Principles, Design, and Operation In this book, the fundamentals of chemical During teaching NMR to students and researchers, engineering are presented aiming to applications we felt the need for a text-book which can cover The subject of this book is centrifugal gas cleaning in micro system technology, microfluidics, and modern trends in the application of NMR to devices, namely cyclones used as gas-solid separa- transport processes within microstructures. After a biological systems. This book caters to the needs tors for dedusting and as gas-liquid separators for general overview on both disciplines and common of: (i) graduate students who mostly learn such demisting. The optimization of cyclone perfor- areas, recent projects are shortly presented. The techniques from senior post-docs in the labora- mance for any given task is an often-sought goal combination of different disciplines gives new tory; (ii) those who are not experts in NMR but is seldom achieved in practice. Understanding opportunities in microfluidic devices and process but wish to understand if a particular problem cyclone performance as a function of a cyclone‘s intensification, respectively. in animal, plant, medical and pharmaceutical size, geometry, feed properties, feed flow rates and Special features of the book are the state of the art sciences can be answered by NMR; and (iii) those the system of which it is a part, is essential if one in micro process engineering, a detailed treatment who are experts in chemistry and biochemistry wishes to successfully design, operate, troubleshoot of transport phenomena for engineers, a design and wish to know how NMR can provide them or predict cyclone performance. The information methodology from transport effects to economic information on structural or functional aspect of presented in this book will help to develop this considerations, a detailed treatment of chemical proteins, nucleic acids, cells and tissues, human understanding. reaction in continuous flow microstructured reac- and plant organs and other biological materials. tors, an engineering methodology to treat complex This book builds a means of knowledge transfer Features processes. between the beginners and the experts in NMR as 7 Gas cyclones and swirl tubes are the most The book addresses researchers and graduate applied to all aspects of life sciences. widely used devices for dedusting or demisting students in the field of chemical engineering, in industry 7 First and only book on this topic Microsystems engineering, and chemistry. Features 7 For industrial engineers wishing to design 7 Covers entire area of NMR in Biological cyclones, or to assess their performance and for Features Sciences (Biomolecules, cells and tissues, animals, beginning researchers 7 Wide overview on fundamental processes in plants and drug design) 7 Most of the NMR chemical and process engineering devices 7 A books focus on one or two of the topics covered in Contents consistent picture form molecular processes to the book 7 Excellent book for teaching a course Introduction.- Basic Ideas.- How Cyclones Work.- continuum regimes 7 Recent and actual state-of- on NMR in Biological Systems Cyclone Flow Pattern and Pressure Drop.- Cyclone the-art in micro process engineering 7 Detailed Separation Efficiency.- The Muschelknautz Method treatment of transport phenomena for engineers Fields of interest of Modeling.- Computational Fluid Dynamics.- 7 Design methodology from transport effects Biotechnology; Physical Chemistry; Imaging / Dimensional Analysis and Scaling Rules.- Other to economic considerations 7 Comprehensive Radiology Factors Influencing Performance.- Measurement picture of mixing characterization Techniques.- Underflow Configurations and Target groups Considerations.- Some Special Topics. From the contents Graduate level students (M.S.) as a graduate Micro Process Engineering - An Interdisci- course, Researchers who wish to understand if a Fields of interest plinary Approach.- Fundamentals, Balances, and particular problem they have in medical and phar- Industrial Chemistry/Chemical Engineering; Transport Processes.- Momentum Transfer.- Heat maceutical sciences would be answered by NMR, Engineering Fluid Dynamics Transfer and Micro Heat Exchangers.- Diffusion, but have no intention to become professional NMR Mixing, and Mass Transfer Equipment.- Chemical spectroscopists, Researchers who are experts in Target groups Reactions and Reactive Precipitation. biochemistry and yet do not know how NMR can Mechanical and chemical engineers help to provide them information on structural or Fields of interest functional aspects of proteins, nucleic acids, cells Discount group Industrial Chemistry/Chemical Engineering; Engi- and tissues, human and plant organs and other P neering Fluid Dynamics; Biomedical Engineering biological materials Target groups Discount group Researchers and graduate students in chemical P engineering, microsystems engineering, chemistry; professionals in the same field

Discount group P

Due January 2008 Due November 2007 Due November 2007 2008 . Approx . 510 p . (Focus on Structural Biology, Volume 6) Hardcover 2nd ed . 2008 . XXVI, 422 p . 218 illus . Hardcover 2007 . Approx . 365 p . (Heat and Mass Transfer) Hardcover 7 $169.00 7 $199.00 7 $139.00 ISBN 978-1-4020-6679-5 ISBN 978-3-540-74694-2 ISBN 978-3-540-74616-4 springer.com/librarybooks Springer News 10/2006 Chemistry 81

L. Lau, M. A. Brodney, Pfizer, Groton, CT, USA (Eds .) D. Schulze, FH Braunschweig/Wolfenbüttel Alzheimer‘s Disease Powders and Bulk Solids Behavior, Characterization, Storage and Flow Revised by: J. Carson Alzheimer’s disease (AD) is a neurodegenerative Translated by: D. Schulze, J. Schwedes disease that robs the minds of ourelderly popula- tion. Approximately one in every eight adults over the age of 65 andnearly half of those over 85 The book concentrates on powder flow proper- are afflicted with this disease. The aging popula- ties, their measurement and applications. These tion indeveloped societies will impose an ever topics are explained starting from the interactions increasing socioeconomic threat in the future. between individual particles up to the design of Current medicines for AD patients are mainly silos. A wide range of problems are discussed symptomatic treatments and a huge unmetmedical – such as flow obstructions, segregation, and need exists to slow the progression of this disease. vibrations. The goal is to provide a deeper under- A great deal of research hasbeen dedicated to standing of the powder flow, and to show practical understanding the pathogenesis of AD from which solutions. comes many ideasfor intervening with its progres- In the first part the fundamentals of bulk solids sion. Some of these ideas have been fast-tracked flow are outlined: particle-particle interactions, toclinical trials due to the availability of medicines stress, friction, strength, density, flow proper- with proven clinical efficacies for otherdiseases ties and methods of measurement, shear testers (e.g. atorvastatin, simvastatin, rosiglitazone and and other test procedures, specific properties of clioquinol) while othersrepresent novel chemical powders and how they are influenced by moisture, entities (e.g. glycogen synthase kinase-3 inhibi- temperature, and flow agents. tors). The second part deals with the application of the flow properties in the design of properly working Features bulk solid containers like bins, silos, and hoppers. 7 In each volume an overview chapter introduces Other topics include: the technical design of silo the newcomer to the topic covered 7 Series walls, feeders, discharge aids, inserts, the assess- covers hot topics of frontier research summarized ment of stresses in silos. by reputed scientists in the field 7 Review series is topic related 7 Online version available on Features SpringerLink: springerlink.com 7 Helps to understand the fundamental behaviour of powders and bulk solids 7 Identifies suitable Contents test methods and helps to interpret and understand G. Grossberg and J. Kao: Cholinesterase Inhibi- their results 7 Explains how bulk solids flow tors.- H. Soares and L. Sparks: Beyond Choles- influences the design of a plant or an installation terol: Statin Benefits in Alzheimer’s Disease.- G. Landreth, S. Mandrekar and Q. Jiang: PPARg Fields of interest Agonists for the Treatment of Alzheimer’s Industrial Chemistry/Chemical Engineering; Disease.- R. Bhat, J. Burrows, J. Lindquist and Industrial and Production Engineering; Quality S. Berg: GSK3 Inhibitors for the Treatment of Control, Reliability, Safety and Risk Alzheimer’s Disease.- A. Bush and A.R. White: Metal Complexing Agents for the Treatment of Target groups AD. Professionals handling or producing powders: in chemical or pharmaceutical industry, in building Fields of interest materials, automotive, power plants, agriculture, Medicinal Chemistry; Pharmacology/Toxicology; waste management, recycling; scientists in these Organic Chemistry fields

Target groups Medicinal chemists working in chemistry, Discount group medicine, pharmacy and biology P

Discount group P

Due November 2007

Due December 2007 Original German edition published with the title: Pulver und Schüttgüter 2008 . Approx . 415 p . 28 illus . (Topics in Medicinal Chemistry, Volume 2) Hardcover 2008 . Approx . 530 p . 352 illus . Hardcover 7 approx. $169.00 7 $139.00 ISBN 978-3-540-74228-9 ISBN 978-3-540-73767-4