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RGUHS Journal of Pharmaceutical Sciences RJPS Contents Vice-Chancellor’S Message

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RGUHS Journal of Pharmaceutical Sciences RJPS Contents Vice-Chancellor’S Message R G U H S Journal of Pharmaceutical Sciences (An Official Publication of RGUHS) April-June 2011 / Vol 1 / Issue 1 Rajiv Gandhi University of Health Sciences, Karnataka 4th ‘T’ Block, Jayanagar, Bangalore 560041 Phone: 080-26961934, 26961935, E-mail: [email protected] Website: www.rjps.in RGUHS Journal of Pharmaceutical Sciences RJPS Contents Vice-Chancellor’s message .......................................................................................................................................................................... 1 Editor-in-Chief ................................................................................................................................................................................................ 2 Executive Editor ............................................................................................................................................................................................. 3 Design and Evaluation of Atenolol Bilayer Buccal Tablets S B Shirsand, P V Swamy and G G Keshavshetti ......................................................................................................................................... 4-10 Evaluation of Disintegrating Properties of Mangifera indica gum Ravi Kumar Nayak, Sachin R Patil, Mrityunjaya B Patil and Mahalaxmi Bhat.............................................................................................. 11-21 A New Reverse Phase High Performance Liquid Chromatographic Method for Determination of Lornoxicam in Bulk and Tablet Dosage Form N C Arjun, J Pavitha and Nagaraj ............................................................................................................................................................... 22-25 Assessment and Evaluation of Drug Information Services provided by the Clinical Pharmcists in a rural tertiary care Teaching Hospital of South India B J Mahendra Kumar, A Sandeep, Bhimaray S Krishnagoudar, Katti Ravi Venkappa and K V Ramanath ................................................... 26-31 Pharmacodynamic interaction of Calcium channel Blockers with garlic during Isoproterenol induced Myocardial Damage in Rat S M B Asdaq, S S Dhamanigi , S Nagpal and R K Rawri .............................................................................................................................. 32-39 Formulation and Evaluation of Orodispersible Tablets of Lansoprazole S S Bushetti, S H Ali, Sunil S Kardame and P P Mane ..................................................................................................................................40-44 Visible Spectro Photometric Determination of Darifenacin Hydrobromide in Bulk and Pharmaceutical dosage forms N K Sathish, Pradeep V Khandelwal, I A Chethan and Ashwinee Kumar Shrestha .......................................................................................45-48 Antihyperglycemic and Antihyperlipidemic effect of Rubia cordifolia leaf extract on Alloxan-induced Diabetes A H M Viswanathaswamy, B C Koti*, A K Singh, and A H M Thippeswamy ................................................................................................... 49-54 Larvicidal and repellent activities of Ethanolic Extract of Pongamia Pinnata Leaves against Mosquitoes S Swathi, G Murugananthan, S K Ghosh and A S Pradeep ......................................................................................................................... 55-57 Physicochemical Properties of flour and isolated starch from Jackfruit seeds (Artocarpus Heterophyllus lam) T Menaka, G Nagaraja, D B Yogesh, U S Sunil Kumar and Prakash L .......................................................................................................... 58-63 Evaluation of Anticonvulsant Activity of Carissa spinarum Root Extract Karunakar Hegde, D Satyanarayana and Arun B Joshi ............................................................................................................................... 64-68 Synthesis and Pharmacological evaluation of Schiff's and Mannich bases of Indole Derivatives P Lohitha, D Giles, C Sreedhar, B Sandhya, A Shravani, T Sunitha and Rajpathi Kumari ............................................................................ 69-78 Antiulcer activity of Ethanolic extract of Gossypium Harbaceum flowers Md. Saifuddin Khalid, S Kamal Hasan, D K Suresh, Raza Hasan, M A Saleem and Zeenath Farooqui ......................................................... 79-84 Preparation and In Vitro Evaluation of Acyclovir Loaded Eudragit® RLPO Nanoparticles as Sustained Release Carriers U V Bhosale and V Kusum Devi .................................................................................................................................................................. 85-92 Instructions to Authors ........................................................................................................................................................................... 93-95 MESSAGE RJPS Our University proved its excellence in the areas of commencement of new courses and programmes, updating curriculum and all other academic related activities such as timely conduct of examinations and announcement of results. With Post Graduate and Ph.D courses in all the disciplines, research was given the due orientation by the university. Research grants were also sanctioned to encourage the fellow researchers, but the publication of research was still in its infancy. Marking the16th Year of its inception, it gives me immense pleasure to announce the year 2011-2012 as the year of “Journal publication” in different disciplines. Continuous surveillance of research activities in the affiliated health institutions of the university, led us to the thought of publication of quality research under one roof. The implementation of the idea was publication of university’s first Journals in Dental as well as Medical Disciplines. These publication received applaud from Academics, Professional and Faculties. The Student Fraternity was not only benefitted but also received encouragement from their own university to move in the direction of publishing their research work. Further, the thought process of publication of journals proliferated into other disciplines and the result is “RGUHS - Journal of Pharmaceutical Sciences” (RJPS). I hope the reader will embrace this publication also and utilize the opportunity to update and upgrade their knowledge. I wish this attempt of publication of scientific work; will also open up a platform for exchange of knowledge within the various disciplines of RGUHS. Dr. S. Ramananda Shetty Vice-Chancellor RGUHS, Karnataka 1 Dear Readers, Rajiv Gandhi University of Health Sciences Journal of Pharmaceutical Sciences, is a new Journal for the pharmaceutical sciences including life sciences, published by Rajiv Gandhi University of Health Sciences. This journal is not beholden to commercial interests or to a scientific society and is therefore free to respond to the needs of authors and readers and offers a truly cost-effective publishing service. RJPS, a quarterly publication, caters for both specialized and interdisciplinary interests and covers all fields related to pharmaceutical sciences. The journal presents research articles and review articles depicting the present status and trends in Pharmaceutical Sciences and related disciplines including Life Sciences. Articles of particular interest covering the areas of pharmaceutical research, teaching & learning, laboratory innovations, education technology, curriculum design, examination reforms, training and other related issues will also be covered. Other notable features of RJPS include fair and transparent evaluation procedures used for acceptability and a double-blind refereeing system. The journal publication is free of cost. This creates the ideal opportunity to try this journal and enjoy the benefits of publishing at no cost. The editorial board along with a large reviewer panel and an experienced advisory board will be involved in evaluating the papers. The members of advisory board and the reviewer panel are drawn from all over India and abroad with proficiency in pharmaceutical sciences and allied fields. I can assure you of a prompt, courteous and unbiased assessment of your manuscript based on clearly stated criteria of acceptability. I am delighted to welcome you to the launch of Rajiv Gandhi University of Health Sciences Journal of Pharmaceutical Sciences. I wish to extend my gratitude to the entire team, Associate editor, Executive editor, the Editorial board members, Reviewer panel and Advisory board as they are the backbone of this scientific endeavor. Editor-in-Chief Prof. B. G. Shivananda Principal Al-Ameen College of Pharmacy Bangalore 2 Dear Readers, “If we knew what it was we were doing, it would not be called research, would it?” – an evocative quote by Albert Einstein Man could well have originated science communication with the early discoveries. Science journalism is the key to the real treasure of the scientific knowledge, by virtue of which scientific knowledge and concepts could be carried to the common man. Thus the common man is benefitted with the new advancements in science and technology. The literature of science is as much about wrong turns, aborted lines of query, failure to flourish, and outright failure as success. Even the greatest of scientists have failed now and again, just like the rest of us. Indeed, unless one is selective to the point of unrepresentativeness, it
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