Fall 2021 CMBB Lecture Series

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Fall 2021 CMBB Lecture Series Mondays 3:30 – 4:50pm via ZOOM Date Guest Speaker Title of Lecture Host Tod Fairbanks, Ph.D. Discover the Way a Biology Degree Can Aug 30 Professor of Biology David Binninger, Ph.D. Guide Your Career Path Palm Beach State College Sept 6 Labor Day (University Closed) Henry Rodriguez, Ph.D., MS, MBA Charting a Federal Career in Molecular Sept 13 Senior Scientific Officer Shailaja Allani, Ph.D. Biology and Biotechnology National Cancer Institute, NIH Jordan Merritt, Ph.D. Malaria and the Immune System: Sept 20 Assistant Director for Partnership Programs Shailaja Allani, Ph.D. What we did, now it’s your Turn! Florida Atlantic University Raul Perez-Olle, M.D., Ph.D. Miguel Lopez-Toledano, Sept 27 Vice President, Medical Affairs Artificial Intelligence in Healthcare Ph.D. MacroGenics, Inc. Saumya Ramanathan, Ph.D. Tumor Specific Antigens (TSA): Letting Oct 4 Assistant Professor of Biochemistry & Molecular Biology Shailaja Allani, Ph.D. Cells go unchecked Fisk University Claudia de Oliveira Rodrigues, Ph.D. Molecular mechanisms of Oct 11 Associate Professor of Biomedical Science Howard Prentice, Ph.D. anthracycline-induced cardiotoxicity Florida Atlantic University Michael Stabin, PhD, CHP Clinical Utility of Radiation Dosimetry Oct 18 Physicist Instructor, NVS/Dade Moeller Gregg Fields, Ph.D. in Radiopharmaceutical Therapy Richland, WA James Foster, Ph.D. Regulation of the Dopamine Assistant Professor Transporter by Palmitoylation: Oct 25 Randy Blakely, Ph.D. School of Medicine and Health Sciences Potential roles in ADHD and University of North Dakota methamphetamine addiction Yangmei Li, Ph.D. Assistant Professor Design and Identification of Novel Nov 1 Mare Cudic, Ph.D. College of Pharmacy Inhibitors targeting DEAD-Box Protein 3 University of South Carolina William G. Kelly, Ph.D. Epigenetic Mechanisms and Nov 8 Professor, Department of Biology Transgenerational “Memory” in C. Lucia Carvelli, Ph.D. Emory University elegans Anne Stone, Ph.D. Tracking a Killer, using ancient DNA to Regents’ Professor Nov 15 understand the Evolutionary History of Kate Detwiller, Ph.D. School of Human Evolution and Social Change Tuberculosis Arizona State University .

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2017 Research Review [PDF]
2017 HIGHLIGHTS Institute of Human Origins Dear Friend of the Institute of Human Origins, It’s hard to believe, but this year marked the 20th anniversary of IHO’s joining Arizona State University, in the hot, hot Phoenix summer of 1997! If you have followed our progress over the past two decades, you will have seen incredible growth and maturation of our organization and our science. Today, we number 15 resident scientists, 8 international affiliates, and 35 PhD students, with field projects around the globe. We have embraced a broad research agenda, from the fossil and archaeological evidence of our origins to the social behavior and genetics of our great ape relatives. And, since 2002, the IHO-affiliated faculty have mentored 26 PhD graduates—17 of them women—who are pursuing their own careers in human origins science, carrying with them the IHO brand of excellence in research and public outreach. IHO’s success is tied to our message that scientific knowledge about human origins is some of the most important knowledge we possess and is particularly relevant in the divisive times we live in. The science of our past shows that our species, Homo sapiens, is linked by common ancestry to all the other species on the Tree of Life; we are not separate from the natural world, we are of it. We are all descended from the same ancestral population that lived in Africa some 200,000 years ago—all groups of people on the planet today are equally related, and none is superior to any other. I find these facts about our origin incredibly exciting—and humbling.
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Rc\Jd S£P 23 2015
ARIZONA STATE UNIVERSITY Molecular Anthropology Laboratory Division of Management Authority US Fish and Wildlife Service RC\JD S£P 23 2015 4401 North Fairfax Dr., Room 700 Arlington, VA 22203 fax: (703) 358-2281 September 9, 2015 Dear Sir or Madam, Enclosed please find an updated renewal application for CITES pennit {#14US094332/9). I am not requesting any changes to the original application. This year, the Molecular Anthropology Laboratory did not import any samples under this CITES permit. We hope to import additional DNA samples during the next year from Africa. These DNA samples are being used for long term scientific research on population genetics and the evolutionary history of great apes and to study the impact of mycobacteria such as M. tuberculosis on primate health and conservation. Better understanding of the population genetics and evolutionary history of the great apes as well as how different bacteria affect their health (and whether they are exchanging disease organisms with humans} will facilitate ongoing conservation efforts of these species. Please contact me with any additional questions. Thank you for your assistance. Sincerely, Anne C. Stone, Ph.D. Laboratory Director Professor [email protected] COLLEGE OF LIBERAL ARTS AND SciENCES School of Human Evolution & Social Change PO Box 872402, Tempe, AZ 85287-2402 {480) 965-6213 FAX: (480) 965-7671 Responses to questions on page 2 on the Pennit application fonn (renewal) 1: pennit number 14US094332/9. 2: The original pennit is attached as Appendix A. 3: This past year, the ASU Molecular Anthropology Laboratory did not import specimens under this CITES permit.
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Darwin's Birthday Debate Wednesday 13Th February 2019 16:00 To
Centre for Ecology and Evolution CEE Event – Darwin’s Birthday Debate Wednesday 13th February 2019 16:00 to 19:00 Flett Lecture Theatre, Natural History Museum, Exhibition Road, London, SW7 5BD Agenda 16:00 Eventopens 16:15 Welcome and Introduction by Professor Andrew Pomiankowski 16:30 Talk1byProfessorAnneStone 17.00 Talk2byProfessorVirpiLummaa 17:30 Questions and discussion 18:00 Wine ReceptionandInformal Networking 19:00 Event finishes The next stage of human evolution Speakers: Professor Anne Stone Arizona State University, USA Website: https://stone.lab.asu.edu/ Twitter: @StoneLab_ASU Professor Virpi Lummaa University of Turku, Finland Website: www.human-life-history.science/ Twitter: @HumanLiHisGroup Abstracts: Professor Anne Stone Title: The future of human evolution: we are what we eat if we survive the pathogens we keep? Abstract: We can gain insight into the future of human evolution by looking at our past. Research in my laboratory focuses on evolutionary history and understanding how humans and other primates have adapted to their environments, including their disease and dietary environments. I will discuss how we use genetic data to understand how diet and disease have shaped our genomes and affected our population history. Speaker bio: Anne Stone is Regents’ Professor in the School of Human Evolution and Social Change at the Arizona State University. Currently, her research focuses on population history and understanding how humans and the great apes have adapted to their environments, including their disease and dietary environments. This includes: (a) Native American population history, (b) the evolutionary history of the Great Apes, and (c) understanding the evolutionary history of mycobacteria (specifically the causative agents of tuberculosis and leprosy).
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Terrence B. Ritzman
Curiculum Vitae TERRENCE B. RITZMAN Department of Archaeology Private Bag X1 University of Cape Town Rondebosch 7701 mobile: 072 964 8811 Cape Town, South Africa fax: 021 650 2352 email: [email protected] www.terryritzman.com www.primate-radiograph.com EDUCATION 2014 Ph.D. in Anthropology Arizona State University (Tempe, AZ, USA) Dissertation Title: A Comparative Radiographic Investigation of Facial Projection in Anthropoid Primates 2005 M.A. in Anthropology Colorado State University (Fort Collins, CO, USA) Thesis Title: Opening the Stone: A Multivariate Reassessment of the Neandertal Status of the Teshik-Tash Child 1999 B.A. in Anthropology University of Illinois at Urbana-Champaign (Urbana-Champaign, IL, USA) EMPLOYMENT/APPOINTMENTS Current Post-Doctoral Research Fellow Department of Archaeology University of Cape Town (Cape Town, South Africa) Supervisor: Prof. Becky Ackermann Funded by the Claude Leon Foundation and the National Research Foundation (South Africa) RESEARCH INTERESTS Human and non-human primate skeletal biology, human anatomy, paleoanthropology, primate craniofacial architecture, evolution of the human and primate brain, phylogenetic comparative methods, multivariate statistical methods, modern human origins, human and primate growth and development PEER-REVIEWED PUBLICATIONS 2014 C. Terhune, C. Robinson. T. Ritzman. Ontogenetic variation in the mandibular ramus of great apes and humans. Journal of Morphology 275(6):661-677. 2013 H. Smith, T. Ritzman, E. Otárola-Castillo, C. Terhune. A 3-D geometric morphometric study of intraspecific variation in the ontogeny of the temporal bone in modern Homo sapiens. Journal of Human Evolution 65(5):479-489. 2012 T. Ritzman, L. Stroik, E. Julik, E. Hutchins, E. Lasku, D.
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Ancient DNA Analysis
Ancient DNA analysis Ludovic Orlando, Robin Allaby, Pontus Skoglund, Clio Der Sarkissian, Philipp Stockhammer, María Ávila-Arcos, Qiaomei Fu, Johannes Krause, Eske Willerslev, Anne Stone, et al. To cite this version: Ludovic Orlando, Robin Allaby, Pontus Skoglund, Clio Der Sarkissian, Philipp Stockhammer, et al.. Ancient DNA analysis. Nature Reviews Methods Primers, 2021, 1 (1), 10.1038/s43586-020-00011-0. hal-03143766 HAL Id: hal-03143766 https://hal.archives-ouvertes.fr/hal-03143766 Submitted on 17 Feb 2021 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Ancient DNA analysis Ludovic Orlando1†, Robin Allaby2, Pontus Skoglund3, Clio Der Sarkissian1, Philipp W. Stockhammer4,5, María C. Ávila-Arcos6, Qiaomei Fu7, Johannes Krause5, Eske Willerslev8,9,10,11, Anne C. Stone12, Christina Warinner5,13 Affiliations 1Centre d’Anthropobiologie et de Génomique de Toulouse, Université Paul Sabatier Toulouse III, Faculté de Médecine Purpan, 37 allées Jules Guesde, Toulouse, France 2School of Life Sciences, University of Warwick, Coventry, United Kingdom 3Ancient
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Neandertals and the Black Swan
Neandertals and the Black Swan DAVID W. FRAYER Department of Anthropology, University of Kansas, Lawrence, KS 66045, USA; [email protected] submitted: 12 January 2019; accepted 20 March 2019 ABSTRACT Neandertals have long been considered remarkably different from modern humans, to the point that most con- sider them a species apart from us. Yet, recent research shows they had many of the same cultural features used to define modernity, such as art and personal ornaments, and, while morphologically different, their behavior be- comes more modern-like with each passing year. We now know they also interbred with moderns and their east- ern relatives, the Denisovans. In many respects these recent discoveries were unanticipated and represent what Taleb calls black swans. A survey of assertions about Neandertals and the subsequent discoveries overturning them should be a lesson for paleoanthropologists when thinking and hypothesizing about their Neandertal cousins. aleb (2010) describes the likelihood of unlikely events what he could say for 20 minutes. I reminded him that Thappening and how it is important for economists to there was a rich database to be mined and he gave an excel- expect the highly improbable. He refers to these as black lent, engaging and, at times, humorous paper. He conclud- swans—unpredicted, unexpected, uncommon events—and ed his abstract by warning that “[s]ince each new critical black swans because the Europeans thought all swans were discovery once again seems to validate the concept that the white until black ones were discovered in Australia. Black data speak for themselves, it is of some interest to carefully swan occurrences so revolutionize a known entity that they discern the messages that are being sent by the fossils.” completely disrupt its perception.
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Origin Stories Episode 12: the Origins of Tuberculosis
Origin Stories Episode 12: The Origins of Tuberculosis Meredith Johnson 0:00:04 This is Origin Stories, The Leakey Foundation podcast. I’m Meredith Johnson. Meredith Johnson Tuberculosis has been part of the human story for a very long time. You might know it as consumption, a turn-of-the-century disease that conjures up images of pale, delicate women coughing into lace handkerchiefs. In the 1800s tuberculosis was causing death and suffering on an incredible scale. In Europe and America, it caused one out of every seven deaths, but people didn’t know what caused it. They thought that consumption maybe ran in families. The only treatments were rest, fresh air, and sunshine and then on March 24, 1882, a scientist named Robert Koch astounded scientific community when he announced he had discovered the cause of tuberculosis. It was a bacteria called Mycobacterium tuberculosis and this announcement was a turning point in our battle against TB. Koch’s discovery gave us an enemy we could fight. It earned him the Nobel Prize and led to advances in hygiene and eventually to the development of antibiotics that worked against the TB pathogen. Now every year on March 24th organizations involved in the fight against TB observe World Tuberculosis Day to raise awareness about this deadly disease. On this episode of Origin Stories, we’re marking World Tuberculosis Day with the first episode in a two-part series about how infectious disease has shaped human evolution. We’ll take a look at our deep history with tuberculosis and hear a surprising story about the origin and evolution of one of the world's deadliest killers and unfortunately, TB isn't only a disease of the past.
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Kirsten I. Bos Curriculum Vitae
Kirsten I. Bos Curriculum Vitae Max Planck Institute for the Science of Human History Kahlaische Str. 10 Jena, Germany 07745 Email: bos[at]shh.mpg.de Personal website: www.kirstenbos.ca Citizenship: Canadian Academic Affiliation Group Leader, Molecular Palaeopathology Max Planck Institute for the Science of Human History, Jena, Germany Research Interests: palaeopathology, infectious disease, ancient DNA, skeletal biology, microbiology, disease resistance Citations since 2013: 1973 h-index since 2013: 15 Education 2012 Doctor of Philosophy, Department of Anthropology, McMaster University Thesis title: Genetic investigations into the Black Death Supervisory committee: Hendrik Poinar (advisor), D. Ann Herring, G. Brian Golding 2006 Ph.D. comprehensive examination completed, “with distinction” 1 2004 Master of Arts, Department of Anthropology, McMaster University Thesis title: Trinitapoli: a preliminary evaluation of the human skeletal material recovered from a Middle Bronze Age burial site in southern Italy Supervisory committee: Shelley R. Saunders (advisor), D. Ann Herring, Anne Keenleyside 2002 pre-Master’s year, University of Manitoba, Department of Anthropology Supervisor: Robert D. Hoppa 2001 Honours Bachelor of Science “with distinction”, Specialized Honours Bio-medical Science, University of Guelph Grants and fellowships Currency shown in Canadian dollars unless otherwise specified 2018 short list, European Research Council (ERC) Starting Grant (requested amount: 1,490,043 euro) 2011 SSHRC postdoctoral fellowship (24 months) ($81,000)
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Kirsten I. Bos Curriculum Vitae
Kirsten I. Bos Curriculum Vitae Max Planck Institute for the Science of Human History Kahlaische Str. 10 Jena, Germany 07745 Email: bos[at]shh.mpg.de Personal website: www.kirstenbos.ca Citizenship: Canadian Academic Affiliation Group Leader, Molecular Palaeopathology Max Planck Institute for the Science of Human History, Jena, Germany Research Interests: palaeopathology, infectious disease, ancient DNA, skeletal biology, microbiology, disease resistance Citations since 2013: 1973 h-index since 2013: 15 Education 2012 Doctor of Philosophy, Department of Anthropology, McMaster University Thesis title: Genetic investigations into the Black Death Supervisory committee: Hendrik Poinar (advisor), D. Ann Herring, G. Brian Golding 2006 Ph.D. comprehensive examination completed, “with distinction” 1 2004 Master of Arts, Department of Anthropology, McMaster University Thesis title: Trinitapoli: a preliminary evaluation of the human skeletal material recovered from a Middle Bronze Age burial site in southern Italy Supervisory committee: Shelley R. Saunders (advisor), D. Ann Herring, Anne Keenleyside 2002 pre-Master’s year, University of Manitoba, Department of Anthropology Supervisor: Robert D. Hoppa 2001 Honours Bachelor of Science “with distinction”, Specialized Honours Bio-medical Science, University of Guelph Grants and fellowships Currency shown in Canadian dollars unless otherwise specified 2018 short list, European Research Council (ERC) Starting Grant (requested amount: 1,490,043 euro) 2011 SSHRC postdoctoral fellowship (24 months) ($81,000)
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Anthroquest Where She Described Her Team’S Prog- Between Physiology and Behavior
no. 32 Fall/Winter 2015 AnthroQ The Newsletter of The Leakeyuest Foundation Leakey Grantee Finds Oldest Jawbone of Genus Homo CHALACHEW MESFIN SEYOUM, INSTITUTE OF HUMAN ORIGINS, ARIZONA STATE UNIVERSITY Arizona State University affiliated researchers and colleagues from other institutions have been searching for hominin remains in Ledi- Geraru, Afar, in the Northeastern part of Ethiopia for the past decade. However, these well-exposed sedimentary outcrops have previ- ously failed to yield any remnants of our ances- tors. While the Ledi-Geraru Research Project was started in 2002, I did not become affili- ated with the project until 2012, when I was invited by Dr. Kaye Reed to work with Dr. Brian Villmoare on any fossil hominins uncov- ered. I joined the fieldwork the following year. In mid-January of 2013, I arrived in Addis Ababa, Ethiopia, unaccompanied by my stowed luggage, which was lost in transit. Unable to claim my baggage, I made the ten-hour trek to Ledi-Geraru in an old Land Cruiser to spend a handful of days in the field before heading back Leakey grantees Brian Villmoare and Chalachew Seyoum at Ledi-Geraru. Photo: J. Rowan to Addis to collect my lost belongings. And hills of coarse sand and loose pebbles. These I held the anterior part of the jaw with part of so, after a week of waiting in Addis, it was on sedimentary hills are separated from each other the third premolar, the roots of the canine, the January 28 that my field season truly began. by water-cut valleys—the erosion of these hills fourth premolar, and the first molar.
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Towards the Origins of Leprosy: Molecular Approaches to Understand One of Mankind's Oldest Diseases
Institute of Evolutionary Medicine (IEM) Symposium Towards the origins of leprosy: molecular approaches to understand one of mankind's oldest diseases Wednesday, May 23th, 2018 12:15-20:00, Irchel Campus, Room Y16-G-15 12:15 – 12:20 Prof. Dr. Dr. Verena Schünemann (Institute of Evolutionary Medicine, University of Zurich): Welcoming words 12:20 – 13:00 Dr. Sarah Inskip (McDonald Institute for Archaeological Research, University of Cambridge): “Osteoarchaeology and leprosy in Medieval England and Iberia.” 13:00 – 13:40 Dr. Helen Donoghue (Centre for Clinical Microbiology, University College London): “Mycobacterium leprae ancient DNA in different populations.” 13:40 – 14:20 Prof. Dr. Dr. Verena Schünemann (Institute of Evolutionary Medicine, University of Zurich): “Ancient Mycobacterium leprae genomics: tracing back leprosy’s past diversity.” 14:20 – 14:45 Break 14:45 – 15:25 Prof. Dr. Ben Krause-Kyora (Institute of Clinical Molecular Biology, Kiel University): “Insights from ancient DNA on the immunogenetics of leprosy.” 15:25 – 16:05 Prof. Dr. David Minnikin (Institute of Microbiology and Infection, University of Birmingham): “Exploring the origins of leprosy.” 16:05 – 16:45 Dr. Andrej Benjak (Global Health Institute, EPFL Lausanne): “World-wide phylogeography of Mycobacterium leprae.” 16:45 – 17:15 Break 17:15 – 18:30 Keynote talk: Prof. Dr. Anne Stone (School of Human Evolution and Social Change, Arizona State University): “The leper's tale: relationships among strains in humans and other animals.” 18:30 – 20:00 Poster session and Apéro All talks are public events and the participation is for free. Please register for the poster session via email to Prof. Dr. Dr.
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Historical, Skeletal, and Molecular Data Leprosy Was the Scourge Of
Journal of Interdisciplinary History, XLIX:3 (Winter, 2019), 367–395. Samuel Mark The Origin and Spread of Leprosy: Historical, Skeletal, and Molecular Data Leprosy was the scourge of ancient societies and continued to be a signiﬁcant health problem in a number of countries until quite recently. A combination of early diagnosis and treatment with multi-drug therapy has greatly re- duced the number of cases of leprosy worldwide, especially in the last twenty-ﬁve years. Today, nearly 83 percent of the more than 200,000 new cases reported annually are from three countries— India, Brazil, and Indonesia. Nevertheless, many Western countries have not yet been able to eradicate leprosy completely. In the United States, the appearance of three strains of M. leprae—SNP subtypes 3K (nine cases), 3J (one case), and 3M (one case)—indicates that new cases continue to arrive from abroad. Another occasional source of infection is apparent contact with armadillos, ranging from Texas to Florida and Georgia. Hence, leprosy continues to remain a health concern even in developed countries. Employing a variety of methods—with attention to both historical sources and molecular data—this article examines the likely origins of leprosy, indicating what we can know about the spread of a disease that has social as well as medical consequences.1 Prior to 2005, India was widely accepted as the country of origin for Mycobacterium leprae primarily due to detailed descrip- tions of the progressive forms of leprosy in the Sushruta Samhita, Samuel Mark is Professor of Maritime Studies, Texas A&M University at Galveston. He is the author of From Egypt to Mesopotamia: A Study of Predynastic Trade Routes (College Station, 1997); Homeric Seafaring (College Station, 2005).
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