bioRxiv preprint doi: https://doi.org/10.1101/2020.09.23.309591; this version posted September 23, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. 1 Rad21l1 cohesin subunit is dispensable for spermatogenesis but not 2 oogenesis in zebrafish 3 4 Yana P. Blokhina1,2,¶, Michelle Frees1,¶, An Nguyen1,¶, Masuda Sharifi1,3, Daniel B. 5 Chu1,2, Bruce W. Draper1, Sean M. Burgess1* 6 7 8 1 Department of Molecular and Cellular Biology, University of California, Davis, 9 California, United States of America 10 11 2 Integrative Genetics and Genomics Graduate Group, University of California, Davis, 12 United States of America 13 14 3 Biochemistry, Molecular, Cellular, and Developmental Biology Graduate Group, 15 University of California, Davis, United States of America 16 17 18 * Corresponding author 19 Email:
[email protected] 20 21 22 ¶ These authors contributed equally to this work. 23 1 bioRxiv preprint doi: https://doi.org/10.1101/2020.09.23.309591; this version posted September 23, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY 4.0 International license. 24 Abstract 25 Meiosis produces haploid gametes that will give rise to the next diploid 26 generation. Chromosome segregation errors occurring at one or both meiotic divisions 27 result in aneuploidy, which can lead to miscarriages or birth defects in humans.