Differential Sperm Motility Mediates the Sex Ratio Drive Shaping Mouse
bioRxiv preprint doi: https://doi.org/10.1101/649707; this version posted May 24, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. Differential sperm motility mediates the sex ratio drive shaping mouse sex chromosome evolution Rathje CC1, Johnson EEP2, Drage D3, Patinioti C1, Silvestri G1, Affara NA2, Ialy-Radio C4, Cocquet J4, Skinner BM2,5, Ellis PJI1,5* 1 School of Biosciences, University of Kent, Canterbury, CT2 7NJ, United Kingdom 2 Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, United Kingdom 3 University Biomedical Services, University of Cambridge, Cambridge, United Kingdom 4 Department of Development, Reproduction and Cancer, INSERM, U1016, Institut Cochin, Paris, France; CNRS, UMR8104, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Faculté de Médecine, Paris, France. 5 These authors contributed equally * Corresponding author: Peter Ellis Email: P.J.I.Ellis @kent.ac.uk Tel: +44(0)1227 82 3526 KEYWORDS: Sex ratio, sex chromosomes, transmission ratio, evolution, sperm, fertilisation 1 bioRxiv preprint doi: https://doi.org/10.1101/649707; this version posted May 24, 2019. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. Summary The search for morphological or physiological differences between X- and Y-bearing mammalian sperm has provoked controversy for decades.
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