Types of Datura Metel
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Evaluation of Antibacterial and Antifungal Activities of Leaf and Seed Extracts of Croton Tiglium Plant Against Skin Disease Causing Microbes
International Journal of Research Studies in Biosciences (IJRSB) Volume 3, Issue 5, May 2015, PP 139-144 ISSN 2349-0357 (Print) & ISSN 2349-0365 (Online) www.arcjournals.org Evaluation of Antibacterial and Antifungal Activities of Leaf and Seed Extracts of Croton Tiglium Plant against Skin Disease Causing Microbes Parbin Iraqui Prof.R.N.S Yadav Dept of Life Sciences, PhD Research Scholar Centre for Studies in Biotechnology Dibrugarh University, Assam, India Director, Centre for Studies in Biotechnology Dibrugarh University, Assam, India [email protected] [email protected] Abstract: Medicinal plants have been used to treat human diseases from the time immemorial. Skin disorders can also be cured using herbal formulations. This study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaf and seed extracts of Croton tiglium plant. The aim of the study was to assesses the antimicrobial activity and to determine the zone of inhibition of leaf and seed extracts of Croton tighlium for potential antimicrobial activity against skin disease causing microbes using agar well diffusion method. The antibacterial and antifungal activities of extracts of Croton tiglium were tested against four bacterial and three fungal strains. Bacterial strains were Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, Pseudomonas aeruginosa and fungal strains were Candida albicans, Trichophyton rubrum and Microsporum canis. Zone of inhibition of extracts were compared with that of standards. The results showed remarkable inhibition of bacterial and fungal growth against tested organisms. The phytochemical analysis was also performed which showed the presence active components like phenol, flavonoids saponins, steroids etc. in the extracts. -
Datura- a Devil Weed Or Angel's Trumpet
Datura- A Devil Weed Or Angel’s Trumpet. Review Article by : Shaheen Bibi Email: [email protected] 1 Datura Inoxia- A Devil weed or Angel’s Trumpet Abstract Datura is a mystery Plant. It belongs to family Solanaceae. There are many important species of genus Datura. Despite of many reports about being toxic, its still debated for its medicinal properties. The genus Datura has a vast history from early time through World War till modern times. Since long time, Datura has been used as a folk medicine in many ancient cultures and even used today. The ethnobotanical information predicts its useful drug value. This plant is well known for its hallucinogenic property. Heiser states that Datura is genus of contrast-from smelly weeds to lovely ornamentals”. 38 Analyzing the chemical profile of Datura , it is reported to be rich in alkaloids. These alkaloids are member of Tropane. Important tropines are Atropine, Scopolamine and Hyoscyamine. The highest in percentage of atropine in D.inoxia is found in its seeds.39 Datura can cause various complications. Some of its effects are systemic. The primary and alarming sign of toxicity with D.inoxia is mydriasis i.e. the change in pupil centration 40,41. Atropine also has the hallucination effect. It blocks the action of acetylcholine at its receptors. Datura inoxia foliage is also harmful for grazing animals or animals that feed on the seeds. Datura inoxia has an anticholinergic property. This property is due to presence of Scopolamine 18. Interestingly, there are beetles and some bees that survive on Datura and they have established certain biochemical mechanisms to defend themselves against the plants intoxicating chemicals. -
Journal of Clinical and Diagnostic Research
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH How to cite this article : PAUDEL R, PALAIAN S, RAVI SHANKAR P, PAUDEL B, , BHATTARAI S. ACONITE POISONING: A CLINICAL REVIEW OF THE FIRST FOUR CASES FROM NEPAL Journal of Clinical and Diagnostic Research [serial online] 2008 February [cited: 2008 February 4]; 2:651-655. Available from http://www.jcdr.net/back_issues.asp?issn=0973-709x&year=2008&month= February &volume=2&issue=1&page=651-655 &id=137 PAUDEL R et al.: Aconite Poisoning: A Clinical Review Of The First Four Cases From Nepal CASE REPORT Aconite Poisoning: A Clinical Review Of The First Four Cases From Nepal PAUDEL R1, PALAIAN S2,3, RAVI SHANKAR P3, PAUDEL B1, BHATTARAI S1 ABSTRACT Aconite tubers are one of the most toxic plant products. They are taken as medication, and are occasionally confused with some other similar plants which are commonly used as medications. This manuscript describes four cases of aconite poisoning that were managed in the Manipal Teaching Hospital. The patients presented with classical symptoms of aconite poisoning such as perioral paraesthesia, generalized burning sensation, and cardiac manifestations such as hypotension and ventricular tachycardia. Since Aconite is a dangerous life threatening herb, one should be aware of this poison. We report four patients who presented with aconite poisoning after mistakenly ingesting aconite, thinking it to be related to medicinal plants. Keywords: Aconite poisoning, Cardiotoxicity, Nepal 1. Department of Medicine, Manipal Teaching Hospital public. The annual incidence of aconitine / Manipal College of Medical Sciences, Pokhara, Nepal poisoning showed a marked decrease from 0.49 to 2 Department of Hospital and Clinical Pharmacy 3. -
Antinociceptive and Smooth Muscle Relaxant Activity of Croton Tiglium L Seed: an In-Vitro and In-Vivo Study
Iranian Journal of Pharmaceutical Research (2012), 11 (2): 611-620 Copyright © 2012 by School of Pharmacy Received: December 2010 Shaheed Beheshti University of Medical Sciences and Health Services Accepted: August 2011 Original Article Antinociceptive and Smooth Muscle Relaxant Activity of Croton tiglium L Seed: An In-vitro and In-vivo Study Zhen Liua, Wenyuan Gaoa*, Jingze Zhanga and Jing Hua,b aSchool of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China. bSchool of Chinese Medicine, Tianjin University of TCM, Tianjin 300193, China. Abstract The seed of Croton tiglium L. (SCT) is a well known folk medicine. In China, it has used to treat gastrointestinal disorders, intestinal inflammation, rheumatism, and so on. Previous studies established its purgative and inflammation properties. In addition, the effects of essential oil of SCT on intestinal transit and gastrointestinal tract has been studied. In the present study, we evaluated the antinociceptive effect of SCT through the writhing test in mice, investigated the effects of it on spontaneous smooth muscle contractions of isolated rabbit jejunum and examined the in-vitro results through the in-vivo small intestine propulsion. We further investigated the possible compounds using HPLC-MS, and six compounds were tentatively identified as phorbol esters. Furthermore, the possible fragmentation pathways of phorbol esters were proposed, and we also detected the possible compounds in the active parts. Keywords: Croton tiglium L; Intestinal propulsion; Smooth muscle; Rabbit jejunum; Antinociceptive; Phorbol esters. Introduction guinea pig colonic smooth muscle cell has been studied, which regulates the gastrointestinal The genus Croton belongs to the family transit in mice, and affects the inflammatory and Euphorbiaceae. -
A Critical Review on Upavisha- Jayapala (Croton Tiglium) ISSN: 2454-5023 Neethu.P.1, Vijitha Vijayan1, Athulya C.M1, Arathi Rajesh2 J
Journal of Ayurvedic and Herbal Medicine 2019; 5(1): 18-21 Review Article A critical review on Upavisha- Jayapala (Croton tiglium) ISSN: 2454-5023 Neethu.P.1, Vijitha Vijayan1, Athulya C.M1, Arathi Rajesh2 J. Ayu. Herb. Med. 1 PG Scholar, Department of Agada Tantra, MVR Ayurveda Medical College, Kannur, Kerala, India 2019; 5(1): 18-21 2 Associate Professor, Department of Agada Tantra, MVR Ayurveda Medical College, Kannur, Kerala, India © 2019, All rights reserved www.ayurvedjournal.com Received: 28-11-2018 ABSTRACT Accepted: 05-02-2019 The word Upavisha means nearer to visha i.e. drugs which possess the same qualities of visha, but not that much potent. Jayapala (Croton tiglium) is one among the upa vishas and a well-known plant in Indian System of Medicine as certain number of formulations include this drug as an ingredient after proper purification. Also it is one of the known purgative drug in Ayurveda with huge theraputic values. This review article includes overall information about the plant jayapala, its botanical description, Toxicological aspect, treatment medicolegal aspects in both Ayurveda and Modern toxicology, its shodhana (purification) processes. Keywords: Upavisha, Croton tiglium. INTRODUCTION Ayurveda is the science of health and healing. In ancient classical literatures Ayurveda was known as the science of eight literatures (Astangas). Agada Tantra is one of the incredible branches among astangas which is used for diagnosis of visha (poisons) and thier management. It is also used for medicolegal cases in the court of law for justice. Generally, visha is classified into Sthavara (inanimate poisons) Jangama) and kritrima visha (artificial poisons). -
Chemical Composition of the Seeds of Datura Innoxia
IJISET - International Journal of Innovative Science, Engineering & Technology, Vol. 3 Issue 2, February 2016. www.ijiset.com ISSN 2348 – 7968 Chemical composition of the seeds of Datura innoxia 1 2 1 2 Kendeson Anawuese ChristianaP ,P Iloka Gabriel SundayP ,P Bulama Joshua SamailaP P andP P Dashak Albert DayilP .P 1 2 P DepartmentP of Chemical Sciences, Federal University Kashere, P.M.B 0182, Gombe, Nigeria. P DepartmentP of Chemistry, University of Jos, P.M.B 2084, Jos, Nigeria. Correspondence Author: [email protected] Abstract The elemental analysis carried out on the seeds of the plant Datura innoxia showed the presence of phosphorus, nitrogen and chlorine. The moisture content was determined and found to be 6.61% ± 0.16. The ash content was 3.08% ± 0.13. The total carbohydrate and reducing sugar contents were determined and found to be 25.07% ± 0.88 and 21.69% ± 1.11 respectively. The lignin content was found to be 5.58% ± 0.16 while the crude fibre content was determined to be 42.42% ± 0.02. The percentage crude protein was found to be 8.64% ± 0.05, and the nitrogen content was determined to be 1.52% ±0.01. The non-polar and polar fat contents were found to be 18.24% ± 0.33 and 23.51% ± 0.25 respectively. The mineral composition of the Datura innoxia was determined and found to contain Ca, Mg, K, Na, Cu, Zn, Mn, Fe, Ni, Cd and Pb. The K, Mg and Ca contents were found to be 3450, 2500, and 2000 mg/100g respectively. -
Insertion of Badnaviral DNA in the Late Blight Resistance Gene (R1a)
Insertion of Badnaviral DNA in the Late Blight Resistance Gene (R1a) of Brinjal Eggplant (Solanum melongena) Saad Serfraz, Vikas Sharma, Florian Maumus, Xavier Aubriot, Andrew Geering, Pierre-Yves Teycheney To cite this version: Saad Serfraz, Vikas Sharma, Florian Maumus, Xavier Aubriot, Andrew Geering, et al.. Insertion of Badnaviral DNA in the Late Blight Resistance Gene (R1a) of Brinjal Eggplant (Solanum melongena). Frontiers in Plant Science, Frontiers, 2021, 12, 10.3389/fpls.2021.683681. hal-03328857 HAL Id: hal-03328857 https://hal.inrae.fr/hal-03328857 Submitted on 30 Aug 2021 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Distributed under a Creative Commons Attribution| 4.0 International License fpls-12-683681 July 22, 2021 Time: 17:32 # 1 ORIGINAL RESEARCH published: 23 July 2021 doi: 10.3389/fpls.2021.683681 Insertion of Badnaviral DNA in the Late Blight Resistance Gene (R1a) of Brinjal Eggplant (Solanum melongena) Saad Serfraz1,2,3, Vikas Sharma4†, Florian Maumus4, Xavier Aubriot5, Andrew D. W. Geering6 and Pierre-Yves Teycheney1,2* -
Cocarcinogenic Principles from the Seed Oil of Croton Tiglium and from Other Euphorbiaceae
ICANCERRESEARCH28,2338-2349,November1968] Cocarcinogenic Principles from the Seed Oil of Croton tiglium and from Other Euphorbiaceae Erich Hecker Biochemisches Institut am Deutschen Krebsforschungszentrum, Heidelberg, Germany first or "initiation" stage of Berenblum experiments as the Introduction result of essentially irreversible biologic events was readily ac cepted. However, the interpretation of the second or "pro The spurge family or Euphorbiacea includes some 280 gen motion" stage remained controversial for many years, espe era and 8000 species which occur in tropical and in temperate regions all over the world. These succulent or nonsucculent cially after a weak but definite tumorigenic activity of croton plants range from herbs and shrubs to tree and cactus types. oil was detected (see Refs. 10, 36). In case of irreversible Many of them contain a milky juice which is more or less tumorigenic events caused by croton oil, the oil would be just toxic, especially for cold-blooded animals, and can produce a another carcinogen. In case of reversible tumorigenic events dermatitis similar to that from poison ivy. The fruits are usual caused by croton oil, a special type of cocarcinogenic activity ly three-celled capsules, each cell containing a single seed from would have been demonstrated which could be called tumor- which in some species toxic, vesicating, and irritant seed oils promoting activity (10). If the nature of the biologic activity may be obtained. The largest genera of the spurge family are of croton oil could be established definitely in the sense of a those of Croton, with about 700 species, and of spurge or tumor promoter rather than as a carcinogen, Berenblum exper Euphorbia, with about 1600 species. -
Medicinal Plant Conservation
MEDICINAL Medicinal Plant PLANT SPECIALIST GROUP Conservation Silphion Volume 11 Newsletter of the Medicinal Plant Specialist Group of the IUCN Species Survival Commission Chaired by Danna J. Leaman Chair’s note . 2 Sustainable sourcing of Arnica montana in the International Standard for Sustainable Wild Col- Apuseni Mountains (Romania): A field project lection of Medicinal and Aromatic Plants – Wolfgang Kathe . 27 (ISSC-MAP) – Danna Leaman . 4 Rhodiola rosea L., from wild collection to field production – Bertalan Galambosi . 31 Regional File Conservation data sheet Ginseng – Dagmar Iracambi Medicinal Plants Project in Minas Gerais Lange . 35 (Brazil) and the International Standard for Sus- tainable Wild Collection of Medicinal and Aro- Conferences and Meetings matic Plants (ISSC-MAP) – Eleanor Coming up – Natalie Hofbauer. 38 Gallia & Karen Franz . 6 CITES News – Uwe Schippmann . 38 Conservation aspects of Aconitum species in the Himalayas with special reference to Uttaran- Recent Events chal (India) – Niranjan Chandra Shah . 9 Conservation Assessment and Management Prior- Promoting the cultivation of medicinal plants in itisation (CAMP) for wild medicinal plants of Uttaranchal, India – Ghayur Alam & Petra North-East India – D.K. Ved, G.A. Kinhal, K. van de Kop . 15 Ravikumar, R. Vijaya Sankar & K. Haridasan . 40 Taxon File Notices of Publication . 45 Trade in East African Aloes – Sara Oldfield . 19 Towards a standardization of biological sustain- List of Members. 48 ability: Wildcrafting Rhatany (Krameria lap- pacea) in Peru – Maximilian -
Setting up of Herbal Gardens in Schools Under Prmotional Scheme of National Medicinal Plants Board (Nmpb), Government of India ======
SETTING UP OF HERBAL GARDENS IN SCHOOLS UNDER PRMOTIONAL SCHEME OF NATIONAL MEDICINAL PLANTS BOARD (NMPB), GOVERNMENT OF INDIA ============================================================ (I) Background :- Realising the resurgence of Indian traditional medicines across the world and corresponding increase in demand of medicinal plants, the Department of AYUSH, Ministry of Health & Family Welfare have set up a Medicinal Plants Board in November, 2000 under the Chairmanship of Union Health & Family Welfare Minister for overall development of this sector. The Board is responsible for co-ordination of all matters relating to medicinal plants, including drawing up policies and strategies for in-situ conservation, ex-situ/in-situ cultivation, proper harvesting, research and development, processing and marketing of raw material etc. in order to protect, sustain and develop this sector. The Board has been implementing Promotional and Commercial schemes and providing Central Assistance for such purposes. (II) Objective : In order to sensitize the students about conservation of the rich biodiversity and in particular the role of medicinal plants in providing a holistic health care both in traditional and modern systems of medicine, it is proposed to provide financial assistance for setting up herbal gardens in schools under the promotional scheme of the Board on a pilot basis. (III) Coverage : As decided in the 13th Standing Finance Committee (SFC) meeting held on 6/7/05, it is proposed to take 10 schools each in 50 districts initially. The project seeks to cover schools up to senior secondary/intermediate/10+2 level with preference being given to Kendriya Vidyalayas and Noarvodaya Vidyalayas. Based on the response and experience of implementation the project will be extended to other districts. -
Two-Step Contractions of Inverted Repeat Region and Psai Gene Duplication from the Plastome of Croton Tiglium (Euphorbiaceae)
Preprints (www.preprints.org) | NOT PEER-REVIEWED | Posted: 23 November 2018 doi:10.20944/preprints201807.0458.v2 Two-Step Contractions of Inverted Repeat Region and psaI Gene Duplication from the Plastome of Croton tiglium (Euphorbiaceae) Sangjin Jo and Ki-Joong Kim School of Life Sciences, Korea University, Seoul 02841, Korea Corresponding author Ki-Joong Kim Anam-ro, Seoul, 02841, Korea Email address: [email protected] Abstract Croton L. (Euphorbiaceae) is a very specious genus and consists of about 1,250 species, mainly distributed in the New World. The first complete plastome sequence from the genus, Croton tiglium, is reported in this study (NCBI acc. no. MH394334). The plastome is 150,021 bp in length. The lengths of LSC and SSC are 111,654 bp and 18,167 bp, respectively. However, the length of the IR region is only 10,100 bp and includes only four rrn and four trn genes, and a small part of the ycf1 gene. We propose two-step IR contractions to explain this unique IR region of the C. tiglium plastome. First, the IR contracted from rps19-rpl2 to ycf2-trnL-CAA on the LSC/IRb boundary. Second, the IR contracted from ycf2-trnL-CAA to rrn16-trnV-GAC on the LSC/IRa boundary. In addition, duplicated copies of psaI genes were discovered in the C. tiglium plastome. Both copies were located side by side between accD and ycf4 genes, but one copy was pseudogenized because of a five-basepair (TAGCT) insertion in the middle of the gene and following frameshift mutation. The plastome contains 112 genes, of which 78 are protein-coding genes, 30 are tRNA genes, and four are rRNA genes. -
Phytosociological Features and Threat Categorization of A. Heterophyllum Wall
Vol. 6(3), pp. 111-118, March 2014 DOI: 10.5897/JENE2013.0395 ISSN 2006-9847 ©2014 Academic Journals Journal of Ecology and the Natural Environment http://www.academicjournals.org/JENE Full Length Research Paper Phytosociological features and threat categorization of A. heterophyllum Wall. ex Royle and A. ferox Wall. ex Ser. in Kumaun Himalaya Deepika Bhatt1, G. C. Joshi1, Ravi Kumar1 and L. M. Tewari2 1Regional research Institute of Himalayan Flora, (CCRAS) Tarikhet, Ranikhet -263 663, Uttarakhand, India. 2Department of Botany, D. S. B. Campus, Nainital, Uttarakhand, India. Accepted 7 January, 2014 Alpine and subalpine regions of Kumaun Himalaya were surveyed qualitatively and quantitatively for the population study to determine the status of Aconitum ferox and A. heterophyllum. Low population density across the surveyed populations and restricted distribution to specific pockets indicates poor availability of the species in the study area. Illegal and over exploitation of these species pose threat to their existence. The present study clarifies the population structure of identified aconite species in Kumaun Himalaya. Observations reveal that on the basis of six attributes (that is habitat preference, distribution range, population size, use pattern, extraction trend, native and endemic species) used to assign threat categories, both the Aconitum species are endangered. Key words: Endangered, Himalaya, Aconitum heterophyllum, Aconitum ferox, medicinal plant. INTRODUCTION Since time immemorial, Himalaya is famous for its rich Indian System of Medicine (ISM). According to Red List plant biodiversity including a wide range of medicinal and Categories published by IUCN (1993), threatened aromatic plants. The variety of soils, topography and species are having small geographic area, narrow habitat climatic conditions of the region provide very congenial specificity, commonly sparse and geographically conditions for growth and development of many thera- restricted to special habitat.