4/20/2018

Tick-Borne Diseases Awareness, understanding and compassion

Dr. Onnie Thatcher

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AGENDA

• -Borne Disease Epidemic • & Co-Infections • Diagnosis & Testing • Acute Treatment • Chronic Disease Treatment & Support • 3 Tests for Tick-Borne (hands-on)

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1 4/20/2018

AN EPIDEMIC

• Tick-borne disease is the most common vector- borne infectious disease in the U.S. • We need to educate our family, friends & patients • We will discuss & demo tools you can use to help your patients

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6 Source: https://www.cdc.gov/lyme/stats/index.html

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Source: Wisconsin Division of Public Health 7

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U.S. MAPS

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5 4/20/2018

U.S. MAPS

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TickNET A Collaborative Public Health Approach to Tick-Borne Disease Surveillance & Research

Figure 2. US cases of Lyme disease, , , , and spotted-fever group rickettsioses reported to the Centers for Disease Control and Prevention, 2001–2013. Counts include confirmed and probable cases, according to the case definition in effect in each year. Anaplasmosis cases were reported as human granulocytic ehrlichiosis before 2008. Ehrlichiosis refers to infections caused by Ehrlichia chaffeensis, E. ewingii, and undetermined species. *Babesiosis was first designated a nationally notifiable condition during 2011.

Source: www.cdc.gov 12

6 4/20/2018

https://wwwnc.cdc.gov/eid/article/21/9/15-0301_article 13

TICK-BORNE DISEASES OF THE U.S.

• Anaplasmosis • Rickettsia parkeri • Babesiosis rickettsiosis • Borrelia mayonii • Rocky Mountain Spotted • Borrelia miyamotoi Fever (RMSF) • • STARI (Southern Tick- Associated Rash Illness) • • Tickborne • Ehrlichiosis (TBRF) • Heartland virus • • Lyme disease • 364D Rickettsiosis • Powassan disease

Source: https://www.cdc.gov/ticks/diseases/index.html 14

7 4/20/2018

WHY IS IT GETTING WORSE?

• Climate • Encroachment • Wildlife management • Toxic environment

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TICK ID

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8 4/20/2018

TICK ID

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DEER TICK

• scapularis • Can carry co-infections and triple infections • Nymphs have had one blood meal, usually from rodents and small animals • Adults have had two blood meals, the second can be larger animals or humans and can carry more infections • Can transmit: Lyme, babesiosis, anaplasmosis, tick , , tularemia, Rocky Mtn. Spotted Fever, and bartonella

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10 4/20/2018

TICKS SPREAD DISEASE VIA FEEDING

Prepares to feed (10 mins to 2 hours)

Drops off, Grasps skin, prepares for cuts into next life surface stage

Ingests host pathogens or transmits Sucks blood Inserts previously for several barbed acquired days feeding tube pathogens to host Secretes “cement” & Cement-like substance to stay anesthetic attached; saliva with anesthetic properties so host can’t feel it 21

NYMPH CAN YOU SEE IT?

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11 4/20/2018

TICK SPECK

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ADULT DOG/WOOD TICK

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12 4/20/2018

ENGORGED TICKS

Nymph Adult

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TICK ATTACHMENT

• Chemoreceptors in legs & arms – Sense body heat, vibrations such as voices and barking, CO2 (exhalation) & movement • Can release from high areas, jump from grasses, twigs, leaves • Also blow thru wind

CT Dept. of Health: “Ticks are found in grassy and overgrown areas where they wait to grasp onto warm bodies that pass by; they do not jump, fly or drop out of trees.” 26

13 4/20/2018

TICK ON SCREEN

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TICKS ON OUR PETS

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14 4/20/2018

TICKS ON BILL (CASE STUDY)

• Tick magnet • MDs thought heart trouble • Tested for Lyme, , Bartonella • After treatment, no longer a tick magnet • Years later he said, “I’m a tick magnet again” – Re-tested, & positive for ticks

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REMOVING TICKS

1. Use fine tip tweezers 2. Grab close to skin 3. Pull straight up • Don’t twist or jerk • Mouthparts may break off & remain in skin*

*Remove the mouth-parts with clean tweezers If unable to remove the mouth easily, leave it alone and let the skin heal

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15 4/20/2018

AVOID FOLKLORE

• Goal = remove tick as quickly as possible – Don’t wait for it to detach

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THOROUGHLY CLEAN BITE & HANDS

Iodine scrub

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16 4/20/2018

PREVENTION • Avoid tall grass & over-grown areas • When hiking, stay in middle of trails • Tuck pant legs into socks • Wear long-sleeved shirts, closed shoes • Wear light-colored clothing – Easier to see ticks for removal • Talk to your veterinarian – Protect pets from tick bites

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CONSIDER TICK REPELLENT

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17 4/20/2018

PERMETHRIN

• Synthetic chemical that acts like natural extracts from chrysanthemum flower • Affects of insects that eat or touch it – Insects can’t break it down as quickly as people & dogs • Broken down by soil microorganisms • Does not mix well with water (doesn’t break down) – Do NOT use near lakes or rivers – Tiny amount can wipe out fish

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RETURNING HOME • Remove clothing outside • Shower using a washcloth or puff to remove unattached ticks • Put clothes in dryer – Heat kills ticks hiding in clothing

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18 4/20/2018

AGENDA

• Tick-Borne Disease Epidemic • Lyme Disease & Co-Infections • Diagnosis & Testing • Acute Treatment • Chronic Disease Treatment & Support • 3 Tests for Tick-Borne (hands-on)

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HISTORY OF LYME IN U.S.

• Lyme Disease on Plum Island – Fringe or government cover-up?

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LYME DISEASE

• 5 subspecies of – Over 100 strains in the US – 300 strains worldwide • This diversity is thought to contribute to the antigenic variability of the spirochete and its ability to evade the immune system and therapy, leading to chronic infection

(From ILADS)

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SPIROCHETES

• Worm-like, coiled bacteria (around for billions of years) • Eight different genera • Over 200 species & counting – Numerous subspecies (they change their genetic structure) – Difficult to find & research – All need a host to survive • Borrelia burgdorferi (Bb) causes Lyme disease – Discovered by researcher Willy Burgdorfer in 1982 – Lyme discovered in 1975 (Lyme, CT) • B. afzelii & B. garinii are primary causes of Lyme in Europe & Asia

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21 4/20/2018

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Production of filamentous B. burgdorferi by ATc-mediated induction of asftsZ RNA. (A) B. burgdorferi 297/tetR cultured for 24 h in the presence of 1.5 μg of ATc/ml (acridine orange staining; magnification, 1,250).

Lydia Dubytska et al. J. Bacteriol. 2006;188:1969-1978

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PLEOMORPHIC FORMS OF BORRELIA

• “…Taken together, the results indicated that B. burgdorferi can change morphology very quickly, adapt and survive in adverse environments, and have pleomorphic forms consisting of DNA as well as antigenic relevant that are freely recognized by the immune system. In addition, B. burgdorferi and its pleomorphic forms have atypical cell wall characteristics and that these sleath round bodies have the ability to become viable spirochetes.”

26 April 2014, ILADS European Conference, Augsburg, Germany Written text by Leena Meriläinen, and Leona Gilbert from Department of Biological and Environmental Sciences and NanoScience 45 Center, University of Jyväskylä, Jyväskylä, Finland

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TRANSMISSION

• Ticks • Fleas • Other biting insects? • Blood transfusion • Crosses through placenta • Possibility in breast milk • Intercourse

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SHOULD WE LIVE IN A BUBBLE?

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ILADS LYME PREVENTION TIPS

49 Source: http://www.ilads.org/lyme/lyme-tips.php

LYME SIGNS & SYMPTOMS “THE GREAT IMITATOR” • Fatigue, chills, fever, headache, muscle & joint aches, swollen lymph nodes, migrating pain • EM rash • Brain fog • Insomnia • Facial or Bell's palsy • Severe headaches and neck stiffness due to meningitis • Joint swelling • Shooting pains that may interfere with sleep • Heart palpitations & dizziness due to changes in heartbeat • Shortness of breath 50

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COMMON LYME CO-INFECTIONS

1. Bartonella 2. Babesia 3. Anaplasmosis 4. Ehrlichiosis

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1. BARTONELLA

• Gram-negative pleomorphic rods • Slow-growing, but fastidious • Cellular targets: erythrocytes & endothelial cells • Hide in RBC’s • Transmitted via fleas, ticks & many think any biting insect • Cause inflammation, fibrin deposits & biofilms in blood vessels

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BARTONELLAE COMMON INFECTION STRATEGY

Alexander Harms, and Christoph Dehio Clin. Microbiol. Rev. 2012;25:42-78

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FLAGELLATION OF BARTONELLA

Alexander Harms, and Christoph Dehio Clin. Microbiol. Rev. 2012;25:42-78

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BARTONELLA RASH

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BARTONELLA EFFECTS

• Damage collagen fibers, causes skin problems such as striae (longitudinal lines) • Damage spongy bone (creating deep bone pain) • Cause vascular neuropathy (from destroying small blood vessels) • Many neurological & psychological symptoms (especially in adolescent boys) • Reaction time decreases, executive function decreases, OCD, slow response

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2. BABESIOSIS (BABESIA)

Description Signs & Symptoms • Protozoa parasite • High fever transmitted by deer ticks • Muscle aches • Invade RBC’s • Chills • Treatment includes anti- • Fatigue microbial agents: • Headache – Atovaquone, AZT, or clyndamycin are typical • Cough • Herbal remedies (anti- • Athralgia parasitical) • Loss of appetite • Anemia

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MICROSCOPIC VIEW OF BABESIA LENGAU SP. NOV.

Anna-Mari Bosman et al. J. Clin. Microbiol. 2010;48:2703- 2708

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BABESIA RASH

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3. ANAPLASMOSIS

Description Symptoms • Discovered in mid 1990s • Typically no rash • Transmitted by deer ticks • Fever • 6 states account for 90% of all • Malaise reported cases (CDC) • Headache – New York, Connecticut, New • Chills Jersey, Rhode Island, Minnesota & Wisconsin • Muscle pain • Needs immediate treatment; • Nausea is recommended • Brain fog antibiotic • Most acute infections feel like – Interestingly, no age limit, as “worst illness they’ve had” with treating Lyme

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ANAPLASMOSIS

Number of annual anaplasmosis cases 1994-2010: The graph displays the number of human cases of anaplasmosis cases reported to CDC annually from 1994 through 2010. Cases of anaplasmosis have generally increased from 350 cases in 2000, when the disease became nationally notifiable, to 1163 cases in 2009. The number of reported cases increased 52% between 2009 and 2010. Source: www.cdc.gov 61

4. EHRLICHIOSIS

Description Symptoms • Transmitted by Lone Star • Malaise • Nausea • Fever • Headache • Muscle pain • Destroys WBC’s • Chills • Used to be considered same • Cough as anaplasmosis • Confusion – They are different

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31 4/20/2018

AGENDA

• Tick-Borne Disease Epidemic • Lyme Disease & Co-Infections • Diagnosis & Testing • Acute Treatment • Chronic Disease Treatment & Support • 3 Tests for Tick-Borne (hands-on)

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“THE GLOBAL SEARCH FOR EDUCATION: TICKS”

“To date in my "Ticks" series, we have learned from leading global experts that tick-borne illnesses (including Lyme disease) are possibly the most complicated and substantial global medical research challenges that exist today and that they threaten to dominate global health care tomorrow. Solutions are tough to find since the bacteria are difficult to diagnose and treat due to the complex multi-disciplinary approach often required.” C.M. Rubin, Huff Post 8/9/13

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LYME TESTING = UNRELIABLE

• Currently there is no reliable test to determine if someone has contracted Lyme disease or is cured of it. False positives and false negatives often occur, though false negatives are far more common. In fact, some studies indicate up to 50% of the patients tested for Lyme disease receive false negative results. As a result, the CDC relies on physicians to make a clinical diagnosis based on a patient's symptoms, health history, and exposure risks. Doctors who are experienced in recognizing Lyme disease will treat when symptoms typical of the illness are present, even without a positive test, in an effort to prevent the development of chronic Lyme disease. (ILADS)

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LAB TESTING FOR LYME

• Enzyme-linked immunosorbent assay (ELISA) – Used most often to detect Lyme disease – Detects antibodies to B. burgdorferi – May not be positive during the early stage of Lyme • Western blot – Used if ELISA is positive, to confirm the diagnosis – Detects antibodies to several proteins of B. burgdorferi • Polymerase chain reaction (PCR) – Detects bacterial DNA in fluid from infected joint • Chronic Lyme arthritis • Persistent infection in the cerebrospinal fluid – Not as effective detecting infection of blood or urine

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LYME TESTING CHALLENGES

• Bacteria hide – Not always detectable in whole blood, even in active disease • Every patient responds differently to infection • Antibodies may only be present for a short time

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IMMUNE-COMPROMISED?

• 4-6 weeks for the antibodies to be produced – Early blood tests may come back negative even if a person is infected

In my opinion, there may never be a positive test if patient is immune-compromised (can’t make antibodies)

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CDC ON ERYTHEMA MIGRANS (EM RASH) aka "bull's-eye" rash

• Occurs in ~70-80% of infected persons • Begins at site of bite after a delay of 3-30 days (avg 7) • Expands gradually over days, up to 12” dia • Feels warm to touch, but rarely itchy or painful • May appear on any area of body

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THE “TYPICAL” BULLSEYE RASH

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CONTROVERSY OVER EM STATS

• ILADS: 35%-60% of cases • CDC: 70%-80% of cases • MN Dept. of Health: “The pathognomonic erythema migrans (EM) rash is present in the majority (but not all) cases of Lyme disease.”

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ILADS ON EM RASH

• Fewer than 50% of patients with Lyme disease recall any rash. Although the erythema migrans (EM) or “bull’s-eye” rash is considered classic, it is not the most common dermatologic manifestation of early-localized Lyme infection. Atypical forms of this rash are seen far more commonly. It is important to know that the EM rash is pathognomonic of Lyme disease and requires no further verification prior to starting an appropriate course of antibiotic therapy.

Source: Ilads.org 72

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PATIENT (O.B.) – EM RASH

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PATIENT EM RASH

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PATIENT (H.C.) - RASH

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PATIENT EM RASH

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PATIENT EM RASH

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OTHER TICK-BORNE EM RASHES

• If we take the medium percentage of EM rashes with Lyme disease at 50%, what would the percentage be for ALL tick-borne diseases (Babesia, Bartonella, etc.) and the chance for a rash/lesion? • Most doctors get an ELISA & Western Blot • Bell’s palsy

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EM DIFFERENTIAL DIAGNOSIS

• Shingles • Hives • Allergic rashes • ivy • • & wasp bites • STARI lesions • Other cutaneous lesions

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WHAT IS THIS?

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LEFT EYELID PARALYSIS

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DIFFERENTIAL DIAGNOSING

• Doesn’t mean every patient has Lyme • Example (C.R.): – 28yo female – All signs & symptoms pointed to tick-borne – I was her 35th Dr.! – She actually had terrible parasites from living in New Guinea

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TEST FOR CO-INFECTIONS

• Testing for Babesia, Anaplasma, Ehrlichia and Bartonella (other tick-transmitted organisms) should be performed. The presence of co- infection with these organisms points to probable infection with the Lyme spirochete as well. If these co infections are left untreated, their continued presence increases morbidity and prevents successful treatment of Lyme disease. (ILADS)

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AGENDA

• Tick-Borne Disease Epidemic • Lyme Disease & Co-Infections • Diagnosis & Testing • Acute Treatment • Chronic Disease Treatment & Support • 3 Tests for Tick-Borne (hands-on)

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ACUTE PHASE OF TICK-BORNE DX

• Hx/environment • Pain • Fever • Moving joint pain/swelling • “Can’t hardly get out of bed” due to weakness

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THE ACUTE PATIENT

I feel strongly that if you find an imbedded tick, you should not wait for symptoms.

One should seek medical assistance in taking doxycycline asap. Many practitioners may disagree with this, but I have experienced it personally several times for myself and my family. The sooner the better. Then, seek help in assisting the digestion, tissue help, co-infection help, etc.

I have found that minocycline does not work well and can cause many problems. Often it is given to a patient instead of doxycycline because it does not create sun sensitivity

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THE ACUTE PATIENT, CONT’D

• Astaxanthin can help with sun sensitivity – Not 100 percent, though • Probiotics in higher than usual dosage are essential – Depending on the patient, other digestive support • Glutathione is a must to help detox the die off & prevent mycotoxins • Other antimicrobials may be needed for co-infections • Things to think about: – Curcumin, rosemary, olive leaf, fish oils, MCT oil, antioxidants, joint & soft tissue support for tissue & inflammation

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RECOMMENDED SUPPLEMENTATION

INFLAMMATION TISSUE SUPPORT DIGESTIVE INFLAMMATION

• Curcumin • Multi-minerals • Digestive enzymes • Omega’s • Collagen support • Oil of oregano • D3 • Glucosamine • Probiotics • MCT oil • Chondroitin • Prebiotics • Natural px • MSM • Magnesium relievers • GI support • MCT oil • Gastro-intestinal lining support • Medical foods

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RECOMMENDED SUPPLEMENTATION

INCREASE OXYGEN EYE SUPPORT MITOCHONDRIA SUPPORT

• • Antioxidants • Medical foods • Baking soda • Astaxanthin • Liposomal glutathione • Blood builders • Bilberry • Antioxidants • Nitric oxide • Lutein • Liver support • Zeaxanthin • Curcumin • Schisandra

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RECOMMENDED SUPPLEMENTATION

INSOMNIA ORAL SUPPORT CARDIOVASCULAR SUPPORT

• Passionflower • • CoQ10 • Valerian root • Toothpaste • Nattokinase • Mg/Ca w/broad • Omega’s spectrum • MCT oil botanicals • Red sage • Chrysanthemum • Hawthorne • Red yeast rice • Niacin

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RECOMMENDED SUPPLEMENTATION

BRAIN SUPPORT DEPRESSION ADRENAL SUPPORT

• Taurine • Emotional • Ashwagandha • B vitamins wellness • Licorice • Gut protection • Protein • Adrenal adaptogens • MCT oil • Ashwagandha • Suma • Curcumin • St John’s Wort • Mucuna pruriens • Omega’s • Omega’s • Astaxanthin • MCT oil • Gingko biloba • Mucuna THYROID SUPPORT pruriens • • Star anise • Iodine • Rosemary • Tyrosine • Chrysanthemum • Suma

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RECOMMENDED SUPPLEMENTATION

ANTIMICROBIALS • Coptis chinensis • Andrographis • Teasel root • Oil of oregano • Star anise • Astragalus • Grapefruit seed extract • Resveratrol • Phllanthus niruri • Colostrum • Iodine (diluted – nasal) • Red sage • Liquid stevia extract • Olive lieaf • Mimosa pudica • D3 • Cistus incanus • Schisandra • Garlic • Mushroom extracts • Smilax • Rosemary • Cat’s claw • Chrysanthemum • Noni • Artemisia • … many more • Neem • Isatis • Tulsi • Pumpkin seed

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ACUTE TREATMENT SUPPORT

• Be careful of any underlying , infections, nutritional depletions, food sensitivities, etc. • Gluten and all sweeteners must be avoided • • Organic • Rest • Plenty of water

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ACUTE SUPPORT SUGGESTIONS

• Preventing Herxheimer effect – Glutathione, mitochondrial support & gut support • Neurological – Taurine, B12 or a complex, nervous system support, amino acids • Sleep aides – Valerian, melatonin, L-tryptophan, passionflower • Tissue repair – Mg, multi-, glucosamine, chondroitin, MSM • Vascular and heart – CoQ10, nattokinase, L-taurine

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DO CURE LYME?

• There has never been a study demonstrating that 30 days of antibiotic treatment cures chronic Lyme disease. However there is a plethora of documentation in the US and European medical literature demonstrating by histology and culture techniques that short courses of antibiotic treatment fail to eradicate the Lyme spirochete. Short treatment courses have resulted in upwards of a 40% relapse rate, especially if treatment is delayed. (ILADS)

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POST-ANTIBIOTICS

• After antibiotic therapy, urgent to: • Rebuild microbiome, support tissue & cognitive function, keep structural integrity, build blood & oxygen levels, exercise, support emotional health & keep immune system strong • You can kill 99% of the infection, but it will never go away until you reclaim your immune system • These infections are stealth fighters • They mutate, exchange info with other bacteria to become resistant, go into cyst forms, hide in biofilms, blood cells, tissue, any soft tissue, aqueous humor of the eyes, etc.

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IMMUNE BUILDING/PREVENTION

• Astaxanthin • Glutathione • Astragalus • Omegas • Cistus Incanus Tea • Prebiotics & • Beta glucan probiotics • Colostrum • Liquid Stevia • Curcumin • Vitamin C • D3 (K) • Mushroom extracts • Garlic (helps repel • Thymus concentrate also)

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ANTI-MICROBIALS

• Golden Thread (Coptis Chinensis) 1,000-1,500 mg TID

• Oil of Oregano- with antimicrobial as catalyst • Probiotics are needed with above two

Cat’s Claw, Artemesia, Grapefruit seed extract, Black Walnut, Pumpkin seed, Teasel Root, Astragalus, Andrographis, Japanese Knotweed (Resveratrol), Red Root, Stephania, Noni, Olive Leaf, Neem, Chinese Skullcap, Isatis, Mimosa, Schisandra, Black Licorice (Star Anise), Tulsi (Holy Basil), Chrysanthemum, Mushroom Extracts, Sarsaparilla….to name a few.

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AGENDA

• Tick-Borne Disease Epidemic • Lyme Disease & Co-Infections • Diagnosis & Testing • Acute Treatment • Chronic Disease Treatment & Support • 3 Tests for Tick-Borne (hands-on)

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CHRONIC LYME, HUFF POST: TICKS

• “The data clearly shows that the major late/chronic forms of Lyme (meningovascular and meningoencephalitis) were clinically and pathologically confirmed and Borrelia burgdorferi was detected in tertiary brain lesions and/or cultivated from the affected brain or cerebrospinal fluid. These observations were made by many authors and in various countries including the USA and Europe. Borrelia burgdorferi is able to evade destruction by the host immune reactions, persist in host tissues and sustain chronic infection and inflammation.” Dr. Judith Miklossy from The Huff Post, “The Global Search for Education: Ticks”, C. M. Rubin. 9/12/13

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TREATING LYME

“Man is a product of nature. What happens to nature happens to us. Polluted, imbalanced nature means polluted, imbalanced people. Secondly, Ultra Dark Field Microscopy (UDFM) is a very advanced science that has been neglected. Currently, I am working with others to make the world aware of Dr. Bela Bozsik from Budapest, who has successfully diagnosed 120,000 Lyme Borreliosis patients with serology and UDFM. Thirdly, antibiotics cannot be half-hearted. You must go all the way with enough to kill but you must supplement with nutrition, minerals, vitamins, enzymes, fatty acids and proper pro-biotics and plant medicines. You have to treat the whole person. I have met with professional herbalists from China, Germany, and Sweden and visited a top modern hospital in Korea where herbalists worked hand in hand with modern chemistry, producing wonders. The Koreans laughed at me when I told them about the low status of in the West. Finally, never neglect the spirit. To get myself healed, I had tremendous help from mental methods. Your mind is capable of feats such as enhancing the immune system beyond what you may believe is possible. So never underestimate the mind to heal. Even Borrelia can be influenced by a properly tuned immune system.”

Dr. Bjorn Overbye from Huff Post, C. M. Rubin, “The Global Search for Education: Norway-Ticks” 101

CHIROPRACTIC ROLE

• Support the whole body • Remove subluxations, create homeostasis • Diet, nutrition & lifestyle coaching • Exercise, stretching, rehab

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USE ALL OF YOUR TOOLS

• Thorough history taking (KEY) • Extensive examinations – Physical, neurological, spinal, extremity – Home assessments, workplace assessments • Lab testing (blood, urine, stool, hair, saliva) • Diagnostic tools (imaging, scopes, computer technology, muscle testing, many more) • Lifestyle coaching – Nutrition, meditation, stress reduction, yoga, Chi Gong, EFT, flower remedies

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NUTRACEUTICALS

• We have the ability to prescribe some of the most potent antimicrobials and immune enhancing substances on the planet

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CREATE HOMEOSTASIS

Adjustments & manual therapies

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EXTREMITIES

It’s important to evaluate & keep the whole musculoskeletal system strong and in alignment

Ex: knee pain – foot & ankle integrity

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TREAT THE PATIENT, NOT THE DISEASE

• Must treat each individual – NO protocols – Each patient is different • Chronic tick-borne infection is the most difficult to tease out the order of treatment necessary for recovery • Case study: Jason – Heavy chelation led to wheelchair

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CHRONIC TICK-BORNE PATIENTS

• Most have suffered “medical abuse” – Long medical history with little or no help – Misdiagnosed or told “it’s all in your head” • Weak, tired & sometimes “checked out” • Many have lived with it so long it’s part of their identity – Flower remedies work well

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EVERY PATIENT COMES WITH BAGGAGE

Doctor MUST assess environmental exposures, food sensitivities, hormonal function, digestive issues, sleep patterns, tissue damage, psychological function, detox pathways, etc.

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AUTOIMMUNE

• Many patients with diagnosed autoimmune conditions have underlying tick-borne infection – Part of cause for immune system turning on itself • They could also have a number of toxicities & infections

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PSYCHIATRIC SYMPTOMS

• Many patient’s get depressed, even suicidal • Can cause many problems with relationships, work, treatment compliance • Think: – Gut-brain – Hormones – Chronic pain • Case study: Nathaniel

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CASE STUDY

• 35-year-old woman • 3 months postpartum • Suicidal, depressed, pain, anxiety • Tried multiple meds • Came to me, showed for Borrelia & Babesia • After 3 weeks of anti-microbials & adrenal support, she was back to herself

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TEAM OF SUPPORT

• Team of healthcare providers • Family support • Community support • If still working, understanding at workplace • Having a loved one at appointment can be helpful, but sometimes they will to hide their suffering from that loved one • I write everything down because of memory

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TEAM APPROACH CASE STUDY

• Jenna • Working with team of NDs • Exit strategy = intense lab work in Germany – Discovered a bacteria not active today but common in dormant stage • Started testing other Lyme patients – 50% tested positive for same bacteria – 99% of positives helped by antimicrobials

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LIFESTYLE & ENVIRONMENT

Home & workplace assessments: • Mold exposure, biofilms • Diet • EMRs/EMFs • Heavy metal

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MOLD EXPOSURE & MYCOTOXIN REMOVAL

• Aspergillus (black mold) produces gliotoxin – Depletes glutathione, suppresses immune system • Healthy dose of probiotics & high quality air purifier can usually Band-Aid a mold exposure until removed • Muscle test dust samples from under refrigerator, top of trim or vacuum dust

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MOLD & MYCOTOXIN BIOFILMS

Chronic Illness Associated with Mold and Mycotoxins: Is Naso-Sinus Fungal Biofilm the Culprit? Joseph H. Brewer,1,* Jack D. Thrasher,2 and Dennis Hooper3 Author information ► Article notes ► Copyright and License information ► This article has been cited by other articles in PMC. Go to: Abstract It has recently been demonstrated that patients who develop chronic illness after prior exposure to water damaged buildings (WDB) and mold have the presence of mycotoxins, which can be detected in the urine. We hypothesized that the mold may be harbored internally and continue to release and/or produce mycotoxins which contribute to ongoing chronic illness. The sinuses are the most likely candidate as a site for the internal mold and mycotoxin production. In this paper, we review the literature supporting this concept.

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BIOFILMS – THEY’RE COMPLICATED

• Can be nearly anywhere – the infection’s hide-out • Different according to strain of infection • Busting up biofilms can be like opening Pandora’s box • Patient must be strong enough before you start – Digesting well, methylating well, hormones balanced, sleeping well, eating well, etc. • Can use the biofilm tester from Life Works* • Can challenge an organ system, see if any of the three muscles go weak, then test biofilm busters with that challenge * AK docs challenge all digestive indicators, brain and eyes. If you have the Life-Work Potential testers, test again using biofilms and lipopolysaccharide if all indicators are strong. 118

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DILUTED IODINE FOR BIOFILM

“study of 250 patients with chronic fatigue, Lyme, – 98% tested positive for gliotoxin”

• Add diluted iodine drops in nose

Source: Joe Brewer, MD at ILADS 2017 conference 121

OTHER BIOFILM BUSTERS

• Nattokinase • Rosemary • Serratiopeptidase • Tulsi • Trypsin • Andrographis • Berberine • Black cumin oil • Curcumin • Neem • Quercetin • Cinnamon • Earthworm protein extract • Clove • Cistus Incanus • Boswellia • Diluted iodine (2 drops in • Apple cider vinegar each nostril & sniff) • MCT oil • Oil of oregano • Garlic

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GLUTEN SUPPORTS BIOFILMS

• Gluten = family of proteins in grains – Wheat, rye, kamut, spelt & barley – Wheat is by far the most commonly consumed • Two main proteins gluten are glutenin & gliadin – Gliadin responsible for most of the negative health effects • When flour & water mixed, gluten proteins form a sticky network that has a glue-like consistency – Makes dough elastic, gives bread ability to rise when baked; provides a chewy, satisfying texture – Name glu-ten is derived from this glue-like property of wet dough.

Source: Medical News Today 123

FOOD

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SUGAR FEEDS INFECTION

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ANTI-INFLAMMATORY DIET

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EMF/EMR EFFECTS

• Activate voltage-gated calcium channels – Most biological effects due to elevated intracellular calcium & consequent nitric oxide (NO) elevation (ML Pall, 2014) • Deplete minerals, causing: – Bone loss, muscle spasticity, cognitive issues, digestive issues, fatigue, decreased pH, etc.

Pall ML. Microwave electromagnetic fields act by activating voltage-gated calcium channels: why the current international safety 127 standards do not predict biological hazard. Recent Res. Devel. Mol. Cell. Biol. 2014(7). ISBN: 978-81-308-0000-0

BIG SOURCES OF EMF/EMR Exposure decreases exponentially with distance from source Keep sleep area “clean”

Base unit on DECT cordless phones constantly emit high EMRs (keep away from bedroom & living areas) 128

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OTHER SOURCES OF EMF/EMR

• Sleep Number beds • Computer monitors • Ceiling fans • Power lines • Vehicle Bluetooth, OnStar • Vehicle seat warmers • Earthing or grounding sheets • Fitness trackers (FitBit) • “Smart” meters

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HEAVY METAL TOXINS

• Toxic soft tissue accumulation of that may otherwise be essential to body function – Lead, mercury, arsenic, cadmium • Caused by – industrial exposure, air or water pollution, foods, medicines, food container coatings, ingestion of lead-based paints, etc. • Symptoms vary, depending on metal

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SOLVENT TOXINS

Source: “Tox Town” 131

AGENDA

• Tick-Borne Disease Epidemic • Lyme Disease & Co-Infections • Diagnosis & Testing • Acute Treatment • Chronic Disease Treatment & Support • 3 Tests for Tick-Borne (hands-on)

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APPLIED KINESIOLOGY (AK)

• Integrated, interdisciplinary approach to healthcare – Originated by Dr. George J. Goodheart, 1964 – Manual muscle testing (MMT) previously established by Kendall & Kendall in 1952 • American Medical Association (AMA) has accepted that the standard method of MMT used in AK is a reliable tool and advocates its use for the evaluation of disability impairments*

* American Medical Association. Guides to the Evaluation of Permanent Impairment, 5th Edition. 2001:510. 133

AK MODEL

• What distinguishes AK from MMT: – Emphasis on proprioceptive responses of the muscle rather than the strength – Sees muscle function as a transcript of the central integrative state of the anterior horn motoneurons, summing all excitatory and inhibitory inputs – Locus of dysfunction ultimately rests with the nervous system • AK model: – Hypertonic muscle secondary to inhibited muscle & inhibited muscle responsive to chiropractic manipulative therapy

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ORDER OF TREATMENT

• Along with symptoms, history, geography, past treatments, exams & labs, using correctly can weed out the infections & the order of treatment • Which order? – Tick-borne, mold, allergy, heavy metal? – The patient may need to be built up before treating some of these items – Find weak muscle, then challenge

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3 AK TESTS FOR TICK-BORNE

• These 3 simple tests will help you determine if the patient needs to seek help 1. Subclavius (immune) 2. Supraspinatus (brain) 3. Quadriceps (hypoxia)

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1. SUBCLAVIUS - IMMUNE

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SUBCLAVIUS TEST

1. Patient sitting or supine 2. Abduct arm 180° to side of head 3. Internally rotate arm so palm faces away from patient – Patient’s biceps should be next to ear with the elbow completely extended 4. Doctor braces the opposite shoulder & abducts the arm away from the head

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2. SUPRASPINATUS - BRAIN

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SUPRASPINATUS TEST

1. Patient seated or supine 2. Abduct the arm 45° & internally rotate so palm faces down (supine) or back (seated) 3. Doctor braces above the wrist & makes sure elbow is in full extension while adducting arm

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3. QUADRICEPS - HYPOXIA

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QUADRICEPS TEST

Test incorporates all four quad muscles & some hip flexors 1. Patient supine, flexes hip & knee to 90° 2. Doctor stands above knee with hand below patella 3. Doctor’s forearm is parallel to ground with elbow at 90° & directs force toward patient’s foot into hip extension

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DETERMINE TREATMENT

If one or more muscles are weak, you can challenge for strength with any supplement, vertebral level or extremity for adjusting, or flower remedy for emotional stability

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DETERMINE DOSING

• Whichever supplements they show for, you can dosage with muscle challenge • Reschedule according to structural needs & timing for finishing supplements • Retest muscles, if still weak, repeat supplement & structural testing

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INSOMNIA & CIRCADIAN RHYTHMS

• To muscle test: – When patient is supine, cover eyes & forehead, which blocks out the pineal gland – If a strong arm goes weak, figure out what is needed

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EXERCISE

• Adrenally fatigued patient should only do gentle exercise – Yoga, walking, tai chi, Gong, etc. • As soon as possible, patient should start higher intensity interval training or burst training for increasing oxygen • Saunas are highly recommended

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DIAPHRAGM & TMJ

• Can cause hernia & digestive problems due to the stress of: – Chronic pain – Holding breath – Clenching teeth, day or night

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CHALLENGES Any kind of trauma or stress can send a message to the bugs to create an attack • To tease out hidden infections when the patient seems better, create body stressors – Muscle fatigue (wall-sit, planks or Superwoman pose), EMF exposure, vagus nerve response, food challenge or wind invasion • Retest the 3 muscles

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TRIGGERS

• Emotional stress – Divorce, death, losing job, moving, etc. • Physical trauma or injury • Illness

Educate patients to make an appointment after any possible trigger; the sooner you find it, the faster it resolves

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CASE STUDIES

• Jon – ALS – Mayo response • Hazel – 11 year-old girl – Strep triggered underlying Lyme – PANDAS

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CAN WE BECOME IMMUNE?

With individualized care, healthy eating and healthy lifestyle habits, I believe we can get stronger and mutate for the better, just as the bugs are doing

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OUR APPROACH

• Life-Work Potential Lyme Plus Test Kit to determine which infections we’re dealing with & to prioritize • Thorough history taking & in-depth AK testing for: – Structure, emotion, EMFs, mycotoxin/fungal, virus, tick- borne, bacteria, parasites, hormone disruptors, heavy metals and solvents, food toxins and foods • Along with psychiatric care, flower remedies can be crucial for chronic patients that are depressed or even suicidal • Creating a team of healthcare practitioners can be most beneficial for the seriously ill patients

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FINAL THOUGHTS

I hope that we, as chiropractors, can emerge and be fully recognized in the mainstream treatment of tick-borne infections. We are experts in how to help the body stay balanced and strong, and we understand the internal mechanisms in which proper nutrition and lifestyle choices can help.

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TAKE HOME POINTS

1. Tick-borne illness is an epidemic 2. Doxycycline is important, but not a cure-all – Still need to address co-infections 3. Treat each patient as an individual – NO protocols, each patient is different 4. When used correctly, 3 AK tests will help you identify tick-borne disease & determine order of treatment

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Dr. Onnie’s email: [email protected] Tina Ashton, Clinic Director: [email protected] www.wholisticfamilyhealthcare.com 715-472-4000 Luck, WI

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ADDITIONAL RESOURCES

• ILADS (International Lyme and Associated Diseases Society) – www.ilads.org • Lyme Disease Association – www.lymediseaseassociation.org • WI Dept of Health Services – https://www.dhs.wisconsin.gov/tickborne/index.htm • MN Dept of Health – http://www.health.state.mn.us/divs/idepc/dtopics/tic kborne/index.html

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