Abstracts Book ISS 2012
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Summary Welcome Message ........................................................................ 3 Symposia Been Held ...................................................................... 4 Programme Structure .................................................................... 5 Summary of Scientific Ativities ...................................................... 6 Scientific Programme .................................................................. 10 Free Theme Programme ............................................................. 19 Poster Programme ...................................................................... 23 Abstracts......................................................................................53 President of Honor Giovanni Gazzinelli Organizing Committee Guilherme Oliveira (President) Roberta Lima Caldeira (Vice-President) Liana K Jannotti Passos (Treasurer) Scientific Committee Carlos Graeff Teixeira (BRA) Charles King (EUA) Constança Barbosa (BRA) Cristina Toscano (BRA) David Rollinson (UK) Glória Regina Franco (BRA) Guilherme Oliveira (BRA) Liana K Jannotti Passos (BRA) Marcelo Fantappie (BRA) Mitermeyer Reis (BRA) Naftale Katz (BRA) Otavio Pieri (BRA) Phil LoVerde (EUA) Renata Guerra (BRA) Roberta Lima Caldeira (BRA) Rosiane A Pereira da Silva (BRA) Sergio Costa Oliveira (BRA) Silvana Thiengo (BRA) Virginia Schall (BRA) Tereza Favre (BRA) Executive Committee Ângela Volpini Cristiano Massara Fernanda Ludolf Larissa Silva Lívia Avelar Luiza Andrade Mariana Magalhães Mariana Oliveira Marina Mourão Ronaldo Scholte Tereza Favre Welcome Message The International Symposium on Schistosomiasis (Simpósio Internacional sobre Esquistossomose) was first held in 1987 and since then there were 12 editions. It is an event that has greatly influenced the scientific community, both nationally and internationally, as has the participation of renowned Brazilian and foreign researchers show that a quality scientific content in their presentations. The International Symposium on Schistosomiasis is the only regular event of its kind worldwide. Historically, the event involved about 350 scientists, undergraduate and graduate students, in addition to professional health services local, state and federal. This year in particular we plan for greater involvement of the international community, with a focus on colleagues from Africa and China. The program of the International Symposium on Schistosomiasis has round tables, conferences, sessions for oral and poster presentations. In addition there will be short courses on molecular biology, epidemiology and genomics. This year, the 13th edition of the event has the theme: “Challenges in the genome era, how to make it deliver”. The event will be held in Belo Horizonte, Minas Gerais. The climate is pleasant with beautiful landscapes and eclectic architecture. The city was considered one of the best cities quality of life in Latin America and is visited by tourists, business tourists, attracted by the local infrastructure and sights in the city and nearby touristic attractions. There will be three awards. The "Pirajá da Silva" award for the best abstract, the "José Pellegrino" award for the best doctoral thesis, and the "Amaury Coutinho" award for the best master thesis defended in the last two years. Welcome to Belo Horizonte! Guilherme Corrêa de Oliveira/President of Organizing Committee Symposia Been Held President City Year 1º Mirian Tendler Rio de Janeiro 1987 2º Naftale Katz Belo Horizonte 1989 3º Amaury Coutinho Recife 1991 4º Mírian Tendler Rio de Janeiro 1993 5º Zilton Andrade Salvador 1995 6º Naftale Katz Belo Horizonte 1997 7º Mírian Tendler Rio de Janeiro 1999 8º Eridan de M. Coutinho Recife 2001 9º Mitermayer Galvão dos Reis Salvador 2003 10º Omar dos Santos Carvalho Belo Horizonte 2005 11º Mitermayer Galvão dos Reis Salvador 2008 12º Carlos Eduardo Grault Rio de Janeiro 2010 Programme Structure Time September 16th September 17 th September 18 th September 19 th Short course Short course Short course 8:00 am 1, 2, 3 1, 2, 3 1, 2, 3 9:00 am Conference Conference Conference Coffee Break Coffee Break Coffee Break 10:00 am Round Round Round 11:00 am Tables Tables Tables Lunch Closing 12:00 am Ceremony Special Lunch Session 1:00 pm 2:00 pm Free Themes Free Themes 3:00 pm Coffee Break Coffee Break 4:00 pm Round Round Tables Tables 5:00 pm Opening Poster Poster 6:00 pm Cerimony Session Session 7:00 pm Cocktail Summary of Scientific Activities Time September 17 th Short course 1 Short course 2 Short course 3 Functional Gene Manipulating the Geoprocessing 08:00 am Analyses by RNA Schistosoma Genomes in Health Conference 09:00 am Chair: Guilherme Oliveira / Speaker: Phil LoVerde Coffee BreaK 10:00 am Round Table 1 Round Table 2 Schistosomiasis elimination 1 Schistosome epigenetics 11:00 am 12:00 am Lunch 1:00 pm Free Themes 1 Free Themes 2 2:00 pm Epidemiology, Sanitation, Control, Drug Development, Elimination of Schistosomiasis Resistance and and Intermediary Hosts Molecular Biology 3:00 pm Coffee BreaK 4:00 pm Round Table 4 Round Table 3 Drug development Immunoregulation and resistance 5:00 pm Poster Session "Epidemiology, Sanitation, Control, Elimination of Schistosomiasis and 6:00 pm Intermediary Hosts" (Poster 1 to 90) Time September 18 th Short course 1 Short course 2 Short course 3 8:00 am Functional Gene Manipulating the Geoprocessing Analyses by RNA Schistosoma Genomes in Health Conference: New schistosomiasis control strategies in Brazil 9:00 am Chair: Naftale Katz/Speaker: Rosa Castália França Ribeiro Soares (Brazilian Ministry of Health)/Discussion: Dr. José Alexandre Menezes da Silva (SANAR Project, PE) Coffee BreaK 10:00 am Round Table 6 Round Table 5 Schistosomiasis Diagnostics 11:00 am evolutionary biology Lunch 12:00 am Special Session 1:00 pm Diagnostics: different formats for different needs. Sponsored by Merck Free Themes 1 Free Themes 2 2:00 pm Biomarkers, Post Genomics, Proteomics, Immunoregulation Epigenetics and Diagnostics and Evolution 3:30 pm Coffee BreaK 4:00 pm Round Table 7 Round Table 8 Informatics and Post genomics, immunomics, Epidemiology proteomics and biomarkers 5:00 pm Poster Session "Biomarkers, Immunoregulation and Diagnostics" "Post Genomics, Proteomics, Epigenetics and Evolution" 6:00 pm "Drug Development, Resistance and Molecular Biology" (Poster 91 to 181) Time September 19 th Short course 1 Short course 2 Short course 3 8:00 am Functional Gene Manipulating the Geoprocessing Analyses by RNA Schistosoma Genomes in Health Conference 3 9:00 am Chair: Dan Colley Big Schisto – the large research consortia Coffee BreaK 10:00 am Round Table 9 Round Table 10 Schistosomiasis elimination 2 Intermediary hosts 11:00 am 12:00 am Closing Ceremony Scientific Programme September 17 th Local: Teatro Oromar Moreira 09:00 - Conference Chair: Guilherme Oliveira Speaker: Phil LoVerde Local: Teatro Oromar Moreira 10:30 - Round Table – Schistosomiasis elimination 1 Chair: David Rollinson (Natural History Museum, London) An overview on the elimination of schistosomiasis - Lester Chitsulo (World Health Organization) Control, schistosomiasis, chemotherapy, sanitation - Naftale Katz (Fiocruz-Minas) The characteristics of epidemic and control of the human schistosomiasis - Jiagang Guo (WHO) Schistosomiasis in Venezuela a neglected among the neglected diseases - Oscar Noya (Universidad Central de Venezuela) Local: Auditório Borges da Costa 10:30 - Round Table – Schistosome epigenetics Chair: Marcelo Fantappie (Federal University of Rio de Janeiro) The SEtTReND project: targeting Schistosoma mansoni histone modifying enzymes for drug development - Raymond Pierce (Institute Pasteur, Lille) The epigenome of Schistosoma mansoni and its plastic response to environmental stress - Christoph Grunau (University of Perpignan) Unveiling the global Schistosoma mansoni methylome - Karl Hoffman (Aberystwyth University) Specific gene repositioning in interphase nuclei of the host organism Biomphalaria glabrata after a schistosome infection - Joanna Bridger (Brunel University) Targeting epigenetics to control schistosomiasis - Marcelo Fantappie (Federal University of Rio de Janeiro) Local: Teatro Oromar Moreira 02:00pm - Free Themes - Epidemiology, Sanitation, Control, Elimination of Schistosomiasis and Intermediary Hosts Chair: Vírginia Torres Schall Risk mapping and prediction of schistosomiasis in Brazil using Bayesian geostatistical models - Ronaldo Scholte et al Susceptibility of Biomphalaria straminea from the São Francisco River basin, Northeast of Brazil, to infection with two strains of S.mansoni - Monica A Fernandez et al Archetypal analysis of Schistosomiasis control in Brazil - Valdir Costa et al Effectiveness of physical therapy in improving of sensory and motor conditions in Schistosomal Myeloradiculopathy: Case report - Tiago Carvalho et al Evaluation of schistosomiasis control activities in the Brazilian PSF - Humberto Quites et al Spatial and temporal-time analysis of prevalence of schistosomiasis autochthonous cases in Pernambuco, 2007 – 2011 - Onício Leal Neto et al Local: Auditório Borges da Costa 02:00pm - Free Themes - Drug Development, Resistance and Molecular Biology Chair: Glória Franco Antischistosomal action of derivative of the thiazole heterocyclic ring LpQM/SC-45: An ultrastructural and cytotoxicity study - Edna de Farias Santiago et al Molecular characterization of TNF-α Receptor homolog (SmTNFR) in Schistosoma mansoni: a new player in the signal transduction puzzle between host-pathogen - Katia C. Oliveira et al Molecular characterization